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UMC Repository: Recent submissions

  • Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2′-Fucosyllactose and 3-Fucosyllactose 
    Zuurveld, Marit; Kiliaan, Pien C.J.; Van Grinsven, Sophie E.L.; Folkerts, Gert; Garssen, Johan; Van't Land, Belinda; Willemsen, Linette E.M. (S. Karger AG, 2023-10-10)
    Allergic sensitization starts with epithelial cell activation driving dendritic cells (DCs) to instruct T helper 2 (Th2) cell polarization. Food allergens trigger intestinal epithelial cell (IEC) activation. Human milk ...
  • Standards of care for CFTR variant-specific therapy (including modulators) for people with cystic fibrosis 
    Southern, Kevin W.; Castellani, Carlo; Lammertyn, Elise; Smyth, Alan; VanDevanter, Donald; van Koningsbruggen-Rietschel, Silke; Barben, Jürg; Bevan, Amanda; Brokaar, Edwin; Collins, Sarah; Connett, Gary J.; Daniels, Thomas W.V.; Davies, Jane; Declercq, Dimitri; Gartner, Silvia; Gramegna, Andrea; Hamilton, Naomi; Hauser, Jenny; Kashirskaya, Nataliya; Kessler, Laurence; Lowdon, Jacqueline; Makukh, Halyna; Martin, Clémence; Morrison, Lisa; Nazareth, Dilip; Noordhoek, Jacquelien; O'Neill, Ciaran; Owen, Elizabeth; Oxley, Helen; Raraigh, Karen S.; Raynal, Caroline; Robinson, Karen; Roehmel, Jobst; Schwarz, Carsten; Sermet, Isabelle; Shteinberg, Michal; Sinha, Ian; Takawira, Constance; van Mourik, Peter; Verkleij, Marieke; Waller, Michael D.; Duff, Alistair (Elsevier, 2023-01)
    Cystic fibrosis (CF) has entered the era of variant-specific therapy, tailored to the genetic variants in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. CFTR modulators, the first variant-specific ...
  • mGlu3 Metabotropic Glutamate Receptors as a Target for the Treatment of Absence Epilepsy: Preclinical and Human Genetics Data 
    Celli, Roberta; Striano, Pasquale; Citraro, Rita; Di Menna, Luisa; Cannella, Milena; Imbriglio, Tiziana; Koko, Mahmoud; De Sarro, Giovambattista; Monn, James A.; Battaglia, Giuseppe; van Luijtelaar, Gilles; Nicoletti, Ferdinando; Russo, Emilio; Koeleman, Bobby; Euro Epinomics-Cogie Consortium (Bentham Science Publishers, 2023-01)
    Background: Previous studies suggest that different metabotropic glutamate (mGlu) receptor subtypes are potential drug targets for treating absence epilepsy. However, no information is available on mGlu3 receptors. Objective: ...
  • Loss of bone morphogenetic protein signaling in fibroblasts results in CXCL12-driven serrated polyp development 
    Ouahoud, Sarah; Westendorp, Barbara Florien; Voorneveld, Philip Willen; Abudukelimu, Subinuer; Koelink, Pim Johan; Pascual Garcia, Elena; Buuren, Jessica Flora Isabella; Harryvan, Tom Jacob; Lenos, Kristiaan Jan; van Wezel, Tom; Offerhaus, Johan Arnold; Fariña-Sarasqueta, Arantza; Crobach, Stijn; Slingerland, Marije; Hardwick, James Christopher Henry; Hawinkels, Lukas Jacobus Antonius Christiaan (Springer, 2023-01)
    Mutations in Bone Morphogenetic Protein (BMP) Receptor (BMPR)1A and SMAD4 are detected in 50% of juvenile polyposis syndrome (JPS) patients, who develop stroma-rich hamartomatous polyps. The established role of stromal ...
  • International Spinal Cord Injury Core Data Set (version 3.0)—including standardization of reporting 
    Biering-Sørensen, Fin; Charlifue, Susan; Chen, Yuying; New, Peter W.; Noonan, Vanessa; Post, Marcel W.M.; Rupp, Rüdiger; Vogel, Lawrence (Springer Nature, 2023-01)
    Study design: Expert opinion, feedback, revisions and final consensus. Objectives: To update the International Spinal Cord Injury (SCI) Core Data Set while still retaining recommended standardization of data reporting. ...
  • Atypical STAT5B deficiency, severe short stature and mild immunodeficiency associated with a novel homozygous STAT5B Variant 
    Catli, Gonul; Gao, Wen; Foley, Corinne; Özyilmaz, Berk; Edeer, Neslihan; Diniz, Gulden; Losekoot, Monique; van Doorn, Jaap; Dauber, Andrew; Dundar, Bumin N.; Wit, Jan M.; Hwa, Vivian (Elsevier Ireland Ltd, 2023-01-01)
    STAT5B deficiency, a rare autosomal recessive disorder characterized by severe growth hormone insensitivity (GHI) and immunodeficiency, can manifest as fatal pulmonary complications. We describe atypical STAT5B deficiency ...
  • The cost-effectiveness of a uniform versus age-based threshold for one-off screening for prevention of cardiovascular disease 
    Špacírová, Zuzana; Kaptoge, Stephen; García-Mochón, Leticia; Rodríguez Barranco, Miguel; Sánchez Pérez, María José; Bondonno, Nicola P.; Tjønneland, Anne; Weiderpass, Elisabete; Grioni, Sara; Espín, Jaime; Sacerdote, Carlotta; Schiborn, Catarina; Masala, Giovanna; Colorado-Yohar, Sandra M.; Kim, Lois; Moons, Karel G.M.; Engström, Gunnar; Schulze, Matthias B.; Bresson, Léa; Moreno-Iribas, Concepción; Epstein, David (Springer-Verlag, 2023-09)
    The objective of this article was to assess the cost-effectiveness of screening strategies for cardiovascular diseases (CVD). A decision analytic model was constructed to estimate the costs and benefits of one-off screening ...
  • A systematic scoping review on contextual factors associated with communicative participation among children with developmental language disorder 
    Singer, Ingrid; de Wit, Ellen; Gorter, Jan Willem; Luinge, Margreet; Gerrits, Ellen (Wiley-Blackwell, 2023-03-01)
    Background: Variations in communicative participation of children with developmental language disorder (DLD) cannot be wholly explained by their language difficulties alone and may be influenced by contextual factors. ...
  • Variables associated with in-hospital and postdischarge outcomes after postcardiotomy extracorporeal membrane oxygenation: Netherlands Heart Registration Cohort 
    Mariani, Silvia; van Bussel, Bas C.T.; Ravaux, Justine M.; Roefs, Maaike M.; De Piero, Maria Elena; Di Mauro, Michele; Willers, Anne; Segers, Patrique; Delnoij, Thijs; van der Horst, Iwan C.C.; Maessen, Jos; Lorusso, Roberto; Van der Kaaij, Niels P.; The Netherlands Heart Registration Cardiothoracic Surgery Registration Committee (Mosby Inc., 2023-03)
    Objectives: Extracorporeal membrane oxygenation (ECMO) for postcardiotomy cardiogenic shock has been increasingly used without concomitant mortality reduction. This study aims to investigate determinants of in-hospital and ...
  • Maxillary overdentures supported by four or six implants in the anterior region: 10-year randomized controlled trial results 
    Slot, Wim; Raghoebar, Gerry M.; Cune, Marco S.; Vissink, Arjan; Meijer, Henny J.A. (Blackwell Munksgaard, 2023-01)
    Aim: To evaluate bar-supported maxillary implant overdenture treatment when supported by either four or six implants after 10 years. Materials and Methods: Edentulous subjects with maxillary denture complaints and ample ...
  • Cranial ultrasound screening in term and late preterm neonates born by vacuum-assisted delivery: Is it worthwhile? 
    Gallo, Dario; Bresesti, Ilia; Bossi, Angela; Lissoni, Donatella; Cromi, Antonella; Tataranno, Maria Luisa; Bertù, Lorenza; Ghezzi, Fabio; Agosti, Massimo (Elsevier (Singapore) Pte Ltd, 2023-01)
    Background: Vacuum extraction is the most common choice to assist vaginal delivery, but there are still concerns regarding the neonatal injuries it may cause. This study aimed to evaluate the rate of intracranial injuries ...
  • A genetics-first approach to understanding autism and schizophrenia spectrum disorders: the 22q11.2 deletion syndrome 
    Fiksinski, Ania M.; Hoftman, Gil D.; Vorstman, Jacob A.S.; Bearden, Carrie E. (Springer Nature, 2023-01)
    Recently, increasing numbers of rare pathogenic genetic variants have been identified that are associated with variably elevated risks of a range of neurodevelopmental outcomes, notably including Autism Spectrum Disorders ...
  • Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohorts 
    Katrinli, Seyma; Wani, Agaz H; Maihofer, Adam X; Ratanatharathorn, Andrew; Daskalakis, Nikolaos P; Montalvo-Ortiz, Janitza; Núñez-Ríos, Diana L; Zannas, Anthony S; Zhao, Xiang; Aiello, Allison E; Ashley-Koch, Allison E; Avetyan, Diana; Baker, Dewleen G; Beckham, Jean C; Boks, Marco P; Brick, Leslie A; Bromet, Evelyn; Champagne, Frances A; Chen, Chia-Yen; Dalvie, Shareefa; Dennis, Michelle F; Fatumo, Segun; Fortier, Catherine; Galea, Sandro; Garrett, Melanie E; Geuze, Elbert; Grant, Gerald; Michael A Hauser; Hayes, Jasmeet P; Hemmings, Sian Mj; Huber, Bertrand Russel; Jajoo, Aarti; Jansen, Stefan; Kessler, Ronald C; Kimbrel, Nathan A; King, Anthony P; Kleinman, Joel E; Koen, Nastassja; Koenen, Karestan C; Kuan, Pei-Fen; Liberzon, Israel; Linnstaedt, Sarah D; Lori, Adriana; Luft, Benjamin J; Luykx, Jurjen J; Marx, Christine E; McLean, Samuel A; Rutten, Bart P F; Vermetten, Eric; Vinkers, Christiaan H; PGC-PTSD Epigenetics Workgroup, PsychENCODE PTSD Brainomics Project, Traumatic Stress Brain Research Group (medRxivCold Spring Harbor Laboratory Press, 2024-07-15)
    BACKGROUND: The occurrence of post-traumatic stress disorder (PTSD) following a traumatic event is associated with biological differences that can represent the susceptibility to PTSD, the impact of trauma, or the sequelae ...
  • Hereditary spherocytosis without pronounced spherocytes on the peripheral blood smear 
    van Asten, Ivar; de Wit, Harry; van Oirschot, Brigitte; van Wijk, Richard; de Vries, Tjalling (Wiley-Blackwell, 2023-02)
  • Twist alters the breast tumor microenvironment via choline kinase to facilitate an aggressive phenotype 
    Vesuna, Farhad; Penet, Marie France; Mori, Noriko; Bhujwalla, Zaver M.; Raman, Venu (Springer Netherlands, 2023-04)
    Twist (TWIST1) is a gene required for cell fate specification in embryos and its expression in mammary epithelium can initiate tumorigenesis through the epithelial-mesenchymal transition. To identify downstream target genes ...
  • Wearable and implantable artificial kidney devices for end-stage kidney disease treatment: Current status and review 
    Groth, Thomas; Stegmayr, Bernd G.; Ash, Stephen R.; Kuchinka, Janna; Wieringa, Fokko P.; Fissell, William H.; Roy, Shuvo (Wiley-Blackwell, 2023-04)
    Background: Chronic kidney disease (CKD) is a major cause of early death worldwide. By 2030, 14.5 million people will have end-stage kidney disease (ESKD, or CKD stage 5), yet only 5.4 million will receive kidney replacement ...
  • Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS 
    Salomon-Zimri, Shiran; Pushett, Avital; Russek-Blum, Niva; Van Eijk, Ruben P.A.; Birman, Nurit; Abramovich, Beatrice; Eitan, Erez; Elgrart, Katya; Beaulieu, Danielle; Ennist, David L.; Berry, James D.; Paganoni, Sabrina; Shefner, Jeremy M.; Drory, Vivian E. (Informa Healthcare, 2023-05)
    Objective: This study aimed to evaluate the safety and tolerability of a fixed-dose co-formulation of ciprofloxacin and celecoxib (PrimeC) in patients with amyotrophic lateral sclerosis (ALS), and to examine its effects ...
  • Endovascular navigation with Fiber Optic RealShape technology 
    Panuccio, Giuseppe; Schanzer, Andres; Rohlffs, Fiona; Heidemann, Franziska; Wessels, Bart; Schurink, Geert W.; van Herwaarden, Joost A.; Kölbel, Tilo (Mosby Inc., 2023-01)
    Objective: Fiber Optic RealShape (FORS) technology has recently been introduced as an adjunctive guidance technology that allows real-time three-dimensional visualization of dedicated endovascular devices while avoiding ...
  • Successful stem cell transplantation in two children with acute leukemia and disseminated, non-resectable Mucorales infection prior to transplantation 
    Beudeker, Coco R.; Froon-Torenstra, Denise; Bresters, Dorine; Loeffen, Yvette G.T.; van Ewijk, Roelof; Goemans, Bianca F. (Wiley-Liss Inc., 2023-02)
  • Primary nonadherence to drugs prescribed by general practitioners: A Dutch database study 
    Hempenius, Mirjam; Rijken, Simone; Groenwold, Rolf H.H.; Hek, Karin; de Boer, Anthonius; Klungel, Olaf H.; Gardarsdottir, Helga (Wiley-Blackwell, 2023-01)
    Aim: Primary nonadherence (PNA) is defined as not filling the first prescription for a drug treatment. PNA can lead not only to poor patient outcomes but also to exposure misclassification in written prescription databases. ...