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UMC Repository: Recent submissions

  • Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly 
    Antonova, Simona V; Haffke, Matthias; Corradini, Eleonora; Mikuciunas, Mykolas; Low, Teck Y; Signor, Luca; van Es, Robert M; Gupta, Kapil; Scheer, Elisabeth; Vos, Harmjan R; Tora, László; Heck, Albert J R; Timmers, H T Marc; Berger, Imre (Nature Research, 2018-12)
    TFIID is a cornerstone of eukaryotic gene regulation. Distinct TFIID complexes with unique subunit compositions exist and several TFIID subunits are shared with other complexes, thereby conveying precise cellular control ...
  • Proteomic Profiling of Two Distinct Populations of Extracellular Vesicles Isolated from Human Seminal Plasma 
    Zhang, Xiaogang; Vos, Harmjan R; Tao, Weiyang; Stoorvogel, Willem (Multidisciplinary Digital Publishing Institute (MDPI), 2020-11-01)
    Body fluids contain many populations of extracellular vesicles (EV) that differ in size, cellular origin, molecular composition, and biological activities. EV in seminal plasma are in majority originating from prostate ...
  • Erratum: Hyperinsulinemia in rats causes impairment of spatial memory and learning with defects in hippocampal synaptic plasticity by involvement of postsynaptic mechanisms (Experimental Brain Research (2013) 226 (45-51) DOI:10.1007/s00221-013-3409-4) 
    Kamal, Amer; Ramakers, Geert M.J.; Gispen, Willem Hendrik; Biessels, Geert Jan (Springer-Verlag, 2013-06)
  • The 2018 correlative microscopy techniques roadmap 
    Ando, Toshio; Bhamidimarri, Satya Prathyusha; Brending, Niklas; Colin-York, H.; Collinson, Lucy; De Jonge, Niels; De Pablo, P. J.; Debroye, Elke; Eggeling, Christian; Franck, Christian; Fritzsche, Marco; Gerritsen, Hans; Giepmans, Ben N.G.; Grunewald, Kay; Hofkens, Johan; Hoogenboom, Jacob P.; Janssen, Kris P.F.; Kaufman, Rainer; Klumpermann, Judith; Kurniawan, Nyoman; Kusch, Jana; Liv, Nalan; Parekh, Viha; Peckys, Diana B.; Rehfeldt, Florian; Reutens, David C.; Roeffaers, Maarten B.J.; Salditt, Tim; Schaap, Iwan A.T.; Schwarz, Ulrich S.; Verkade, Paul; Vogel, Michael W.; Wagner, Richard; Winterhalter, Mathias; Yuan, Haifeng; Zifarelli, Giovanni (Institute of Physics, 2018-08-31)
    Developments in microscopy have been instrumental to progress in the life sciences, and many new techniques have been introduced and led to new discoveries throughout the last century. A wide and diverse range of methodologies ...
  • Cannabis-related treatment demand at the eve of German cannabis legalization - a 20-years trend analysis 
    Stampf, Alisa; Schwarzkopf, Larissa; Batalla, Albert; Feingold, Daniel; Fischer, Benedikt; Hoch, Eva; Advisory Board of the German Addiction Care Statistical Service (D. Steinkopff-Verlag, 2025-03)
    Post-2000, the prevalence of cannabis consumption has been rising internationally. This paper investigates whether cannabis-related treatment demand in German outpatient addiction care facilities (OACFs) has been following ...
  • Reliability of mandibular range of motion measurements in healthy children 
    de Sonnaville, Willemijn F.C.; Steenks, Michel H.; Verkouteren, Daan R.C.; Zuithoff, Nicolaas P.A.; Wulffraat, Nico M.; Rosenberg, Antoine J.W.P.; Speksnijder, Caroline M. (Wiley-Blackwell, 2024-10)
    Background: Mandibular range of motion (MROM) variables are widely used to evaluate oral function. Objective: The aim of this study was to establish the reliability of MROM variables in healthy children. Methods: In this ...
  • ‘This form could give me the courage to address otherwise undiscussed topics’: student reasons for (not) impacting their feedback environment 
    Postmes, Lieselotte; de Kleijn, Renske; Bouwmeester, Rianne; van der Schaaf, Marieke (Taylor and Francis Ltd., 2025)
    Students are increasingly expected to take up proactive roles in feedback processes. While most feedback research focuses on asking, receiving, and engaging with feedback, some suggest that students must also proactively ...
  • Anatomical distribution and treatment of paediatric hand fractures: a multi-centre study of 749 patients in the Netherlands 
    Snapshot Hand Fractures Collaborative Study Group (SAGE Publications Ltd, 2025-02)
    This study describes the anatomical distribution of paediatric metacarpal and phalangeal fractures and evaluates treatment methods for each fracture type. A multicentre study was conducted over a 3-month period in the ...
  • Birthweight charts customised for maternal height optimises the classification of small and large-for-gestational age newborns 
    Zeegers, Bert; Offerhaus, Pien; Hoftiezer, Liset; Groenendaal, Floris; Zimmermann, Luc J.I.; Verhoeven, Corine; Gordijn, Sanne J.; Nieuwenhuijze, Marianne J. (Wiley-Blackwell, 2024-10)
    Aim: To construct birthweight charts customised for maternal height and evaluate the effect of customization on SGA and LGA classification. Methods: Data were extracted (n = 21 350) from the MiCaS project in the Netherlands ...
  • Statistical Analysis Plan for the INTEnsive Ambulance-Delivered Blood Pressure Reduction in Hyper-ACute Stroke Trial 
    Billot, Laurent; Chen, Chen; Song, Lili; Lin, Yapeng; Liu, Feifeng; Chen, Xiaoying; Arima, Hisatomi; Bath, Philip M.; Ford, Gary A.; Robinson, Thompson G.; Sandset, Else Charlotte; Saver, Jeffrey L.; Sprigg, Nikola; Van Der Worp, H. Bart; Yang, Jie; Li, Gang; Anderson, Craig S. (S. Karger AG, 2025)
    Introduction: Recruitment is complete in the fourth INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4), a multicenter, prospective, randomized, open-label, blinded endpoint ...
  • Association between bronchopulmonary dysplasia severity and its risk factors and long-term outcomes in three definitions: A historical cohort study 
    Katz, Trixie A.; Van Kaam, Anton H.; Zuithoff, Nicolaas P.A.; Mugie, S. M.; Beuger, Sabine; Blok, Geert Jan; Van Kempen, Anne A.M.W.; Van Laerhoven, Henriëtte; Lutterman, Claire A.M.; Rijpert, Maarten; Schiering, Irene A.; Ran, Nicolien C.; Visser, Fenna; Van Straaten, Els; Aarnoudse-Moens, Cornelieke S.H.; Van Wassenaer-Leemhuis, Aleid G.; Onland, Wes (BMJ Publishing Group, 2024-12-20)
    Objective: To compare the association of the severity categories of the 2001-National Institutes of Health (NIH), the 2018-NIH and the 2019-Jensen bronchopulmonary dysplasia (BPD) definitions with neurodevelopmental and ...
  • Fecal, Duodenal and Tumor Microbiota Composition of Esophageal Carcinoma Patients, a Longitudinal Prospective Cohort 
    van den Ende, Tom; de Clercq, Nicolien C; Davids, Mark; Goedegebuure, Ruben; Doeve, Benthe H; Ebrahimi, Gati; Buijsen, Jeroen; Hoekstra, Ronald; Mohammad, Nadia Haj; Bijlsma, Maarten F; Nieuwdorp, Max; van Laarhoven, Hanneke W M (Oxford University Press, 2024-11)
    BACKGROUND: The microbiome has been associated with chemotherapy and immune checkpoint inhibitor efficacy. How this pertains to resectable esophageal carcinoma is unknown. Our aim was to identify microbial signatures in ...
  • Gamification in eHealth for Chronic Disease Self-Management in Youth: A Systematic Review 
    Stutvoet, Maartje D.; Levelt, Lisa; Hrehovcsik, Micah M.; van’t Veer, Job; Visch, Valentijn T.; Bramer, Wichor M.; Hillegers, Manon H.J.; Veltkamp, Remco C.; Nijhof, Sanne L.; Estévez-López, Fernando (Mary Ann Liebert Inc., 2024)
    This systematic review primarily aims to provide a summary of the game mechanics implemented in eHealth tools supporting young people’s self-management of their chronic diseases. This review secondarily investigates the ...
  • Predictors of malignancy in melanocytic lesions presenting as new lesions compared to baseline total body photography: A case–control study 
    Chan, S.; Guitera, P.; Ferguson, P.; El Sharouni, M. A.; Teh, R.; Scolyer, R. A.; Glanz, A. (Wiley-Blackwell, 2025-03)
    Background: Only a small per cent of new melanocytic lesions developing in adults are expected to represent melanomas. Total body photography (TBP) has been widely incorporated in clinical practice, especially for follow-up ...
  • International consensus on the management of large (≥20 mm) colorectal laterally spreading tumors: World Endoscopy Organization Delphi study 
    Djinbachian, Roupen; Rex, Douglas K; Chiu, Han-Mo; Fukami, Norio; Aihara, Hiroyuki; Bastiaansen, Barbara A J; Bechara, Robert; Bhandari, Pradeep; Bhatt, Amit; Bourke, Michael J; Byeon, Jeong-Sik; Cardoso, Daniela; Chino, Akiko; Chiu, Philip W Y; Dekker, Evelien; Draganov, Peter V; Elkholy, Shaimaa; Emura, Fabian; Goldblum, John; Haji, Amyn; Ho, Shiaw-Hooi; Jung, Yunho; Kawachi, Hiroshi; Khashab, Mouen; Khomvilai, Supakij; Kim, Eun Ran; Maselli, Roberta; Messmann, Helmut; Moons, Leon; Mori, Yuichi; Nakanishi, Yukihiro; Ngamruengphong, Saowanee; Parra-Blanco, Adolfo; Pellisé, María; Pinto, Rafael Castilho; Pioche, Mathieu; Pohl, Heiko; Rastogi, Amit; Repici, Alessandro; Sethi, Amrita; Singh, Rajvinder; Suzuki, Noriko; Tanaka, Shinji; Vieth, Michael; Yamamoto, Hironori; Yang, Dong-Hoon; Yokoi, Chizu; Saito, Yutaka; von Renteln, Daniel (John Wiley & Sons Inc., 2024-11)
    OBJECTIVES: There have been significant advances in the management of large (≥20 mm) laterally spreading tumors (LSTs) or nonpedunculated colorectal polyps; however, there is a lack of clear consensus on the management of ...
  • Interobserver agreement of current and new proposed endoscopic scores for postoperative recurrence in Crohn's disease 
    Bak, Michiel T J; Hammoudi, Nassim; Allez, Matthieu; Silverberg, Mark S; Schellekens, Isa M; Erler, Nicole S; Dijkstra, Gerard; Romberg-Camps, Mariëlle; de Boer, Nanne K H; Jansen, Sita V; van der Marel, Sander; Horjus, Carmen S; Visschedijk, Marijn C; Goetgebuer, Rogier L; van Dop, Willemijn A; Hoekstra, Jildou; Bodelier, Alexander G L; Molendijk, Ilse; Derikx, Lauranne A A P; van Schaik, Fiona D M; West, Rachel L; Duijvestein, Marjolijn; van der Woude, C Janneke; van Ruler, Oddeke; de Vries, Annemarie C; Dutch Initiative on Crohn and Colitis and the RAP-CD study group (Mosby Inc., 2024-10)
    Background and Aims: The modified Rutgeerts score (mRS) is widely used for the assessment of endoscopic postoperative recurrence (ePOR) in Crohn's disease (CD) after ileocolic resection to guide therapeutic decisions. To ...
  • High Neuraxial Block in Obstetrics: A 2.5-Year Nationwide Surveillance Approach in the Netherlands 
    Beenakkers, Ingrid C M; Schaap, Timme P; van den Bosch, Oscar F C (Lippincott Williams & Wilkins, 2024-12)
    BACKGROUND: High neuraxial block is a rare but serious adverse event in obstetric anesthesia that can ultimately lead to respiratory insufficiency and cardiac arrest. Previous reports on its incidence are limited to ...
  • Consistencies in Follow-up After Radical Cystectomy for Bladder Cancer: A Framework Based on Expert Practices Collaboratively Developed by the European Association of Urology Bladder Cancer Guideline Panels 
    Mertens, Laura S; Bruins, Harman Maxim; Contieri, Roberto; Babjuk, Marek; Rai, Bhavan P; Puig, Albert Carrión; Escrig, Jose Luis Dominguez; Gontero, Paolo; van der Heijden, Antoine G; Liedberg, Fredrik; Martini, Alberto; Masson-Lecomte, Alexandra; Meijer, Richard P; Mostafid, Hugh; Neuzillet, Yann; Pradere, Benjamin; Redlef, John; van Rhijn, Bas W G; Rouanne, Matthieu; Rouprêt, Morgan; Sæbjørnsen, Sæbjørn; Seisen, Thomas; Shariat, Shahrokh F; Soria, Francesco; Soukup, Viktor; Thalmann, George; Xylinas, Evanguelos; Mariappan, Paramananthan; Alfred Witjes, J (Elsevier, 2025-02)
    BACKGROUND AND OBJECTIVE: There is no standardized regimen for follow-up after radical cystectomy (RC) for bladder cancer (BC). To address this gap, we conducted a multicenter study involving urologist members from the ...
  • Topical or oral antibiotics in childhood acute otitis media and ear discharge: a randomized controlled non-inferiority trial 
    Hullegie, Saskia; Damoiseaux, Roger A M J; Hay, Alastair D; Zuithoff, Nicolaas P A; van Dongen, Thijs M A; Little, Paul; Schilder, Anne G M; Venekamp, Roderick P (Oxford University Press, 2024-10-01)
    BACKGROUND: Current guidance suggests oral antibiotics can be considered for children with acute otitis media (AOM) and ear discharge, but there is an absence of evidence regarding the relative effectiveness of ...
  • Vasodilator reactive oxygen species ameliorate perturbed myocardial oxygen delivery in exercising swine with multiple comorbidities 
    van Drie, R W A; van de Wouw, J; Zandbergen, L M; Dehairs, J; Swinnen, J V; Mulder, M T; Verhaar, M C; MaassenVanDenBrink, A; Duncker, D J; Sorop, O; Merkus, D (Springer Science and Business Media Deutschland GmbH, 2024-10)
    Multiple common cardiovascular comorbidities produce coronary microvascular dysfunction. We previously observed in swine that a combination of diabetes mellitus (DM), high fat diet (HFD) and chronic kidney disease (CKD) ...