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UMC Repository: Recent submissions

  • Cost Effectiveness of Rectal Culture-based Antibiotic Prophylaxis in Transrectal Prostate Biopsy: The Results from a Randomized, Nonblinded, Multicenter Trial 
    Tops, Sofie C.M.; Kolwijck, Eva; Koldewijn, Evert L.; Somford, Diederik M.; Delaere, Filip J.M.; van Leeuwen, Menno A.; Breeuwsma, Anthonius J.; de Vocht, Thijn F.; Broos, Hans J.H.P.; Schipper, Rob A.; Steffens, Martijn G.; Wegdam-Blans, Marjolijn C.A.; de Brauwer, Els; van den Bijllaardt, Wouter; Leenders, Alexander C.A.P.; Sedelaar, J. P.Michiel; Wertheim, Heiman F.L.; Adang, Eddy (Elsevier, 2023-04)
    Background: Culture-based antibiotic prophylaxis is a plausible strategy to reduce infections after transrectal prostate biopsy (PB) related to fluoroquinolone-resistant pathogens. Objective: To assess the cost effectiveness ...
  • The impact of the covid-19 pandemic on diabetes care: the perspective of healthcare providers across Europe 
    Van Grondelle, S. E.; Van Bruggen, S.; Rauh, S. P.; Van der Zwan, M.; Cebrian, A.; Seidu, S.; Rutten, G. E.H.M.; Vos, H. M.M.; Numans, M. E.; Vos, R. C. (Elsevier, 2023-04)
    Aims: Covid-19 caused changes on the delivery of diabetes care. This study aimed to explore perceptions of healthcare providers across Europe concerning 1) the impact of covid-19 on delivery of diabetes care; 2) impact of ...
  • Statistical Morphology and Fragment Mapping of Complex Proximal Humeral Fractures 
    Mys, Karen; Visscher, Luke; van Knegsel, Kenneth Petrus; Gehweiler, Dominic; Pastor, Torsten; Bashardoust, Amirsiavosh; Knill, Anna Sophie; Danker, Carolin; Dauwe, Jan; Mechkarska, Rayna; Raykov, Georgi; Karwacki, Grzegorz Marek; Knobe, Matthias; Gueorguiev, Boyko; Windolf, Markus; Lambert, Simon; Nijs, Stefaan; Varga, Peter (Multidisciplinary Digital Publishing Institute (MDPI), 2023-02)
    Background and Objectives: Proximal humerus fractures (PHFs) are common in the elderly, but the treatment results are often poor. A clear understanding of fracture morphology and distribution of cortical bone loss is ...
  • Inhibition of ventral tegmental area projections to the nucleus accumbens shell increases premature responding in the five-choice serial reaction time task in rats 
    Flores-Dourojeanni, Jacques P.; van den Munkhof, Marleen H.; Luijendijk, Mieneke C.M.; Vanderschuren, Louk J.M.J.; Adan, Roger A.H. (Springer-Verlag, 2023-05)
    Exaggerated impulsivity and attentional impairments are hallmarks of certain disorders of behavioural control such as attention-deficit/hyperactivity disorder (ADHD), schizophrenia and addiction. Pharmacological studies ...
  • Antibiotic effectiveness for children with lower respiratory infections: prospective cohort and trial in primary care 
    Little, Paul; Becque, Taeko; Hay, Alastair D.; Francis, Nick A.; Stuart, Beth; O’Reilly, Gilly; Thompson, Natalie; Hood, Kerenza; Moore, Michael; Verheij, Theo (Royal College of General Practitioners, 2023-03)
    Background Antibiotics are commonly prescribed for children with chest infections but there is little randomised evidence and trials commonly recruit selected populations, which undermines their applicability. Aim To ...
  • Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages 
    van Wouw, Suzanne A.E.; van den Berg, Marlene; El Ouraoui, Maroua; Meurs, Amber; Kingma, Jenina; Ottenhoff, Roelof; Loix, Melanie; Hoeksema, Marten A.; Prange, Koen; Pasterkamp, Gerard; Hendriks, Jerome J.A.; Bogie, Jeroen F.J.; van Klinken, Jan B.; Vaz, Frederic M.; Jongejan, Aldo; de Winther, Menno P.J.; Zelcer, Noam (American Society for Biochemistry and Molecular Biology Inc., 2023-02)
    Lysoplasmalogens are a class of vinyl ether bioactive lipids that have a central role in plasmalogen metabolism and membrane fluidity. The liver X receptor (LXR) transcription factors are important determinants of cellular ...
  • Treatment patterns and survival in older adults with unresected nonmetastatic biliary tract cancers 
    Belkouz, Ali; de Savornin Lohman, Elise; Thumma, Jyothi R.; Groot Koerkamp, Bas; de Reuver, Philip R.; van Oijen, Martijn G.H.; Punt, Cornelis J.A.; Nathan, Hari; Klümpen, Heinz Josef (Elsevier, 2023-04)
    Introduction: The optimal treatment for unresected nonmetastatic biliary tract cancer (uBTC) is not well-established. The objective of this study was to analyze the treatment patterns and compare the differences in overall ...
  • Editor's Choice – Interventions to Achieve Functionality in Newly Created Arteriovenous Fistulas in the Shunt Simulation Study Cohort 
    van Vliet, Letty V.; Zonnebeld, Niek; Bouwman, Lee H.; Cuypers, Philippe W.; Huisman, Laurens C.; Lemson, Susan; Schlösser, Felix J.; de Smet, André A.; Toorop, Raechel J.; Snoeijs, Maarten G.; Delhaas, Tammo; Heinen, Stefan G.; Huberts, Wouter; Mees, Barend M.; Tordoir, Jan H.; Shunt Simulation Study Group (W.B. Saunders Ltd, 2023-04)
    Objective: Although observational cohort studies report that interventions to achieve functionality are clinically successful in 85% of patients, the proportion of newly created autologous arteriovenous fistulas that result ...
  • Unhelpful thoughts and distress regarding symptoms are associated with recovery from upper extremity fracture 
    Teunis, Teun; Ramtin, Sina; Gwilym, Stephen E.; Ring, David; Jayakumar, Prakash (Elsevier, 2023-04)
    Background: There is evidence that thoughts and emotions regarding symptoms are strongly associated with levels of comfort and capability for a given injury or disease. Longitudinal data from a large cohort of people ...
  • Presence of retinopathy and incident kidney and cardiovascular events in type 2 diabetes with normoalbuminuria – A post-hoc analysis of the PRIORITY randomized clinical trial 
    Rotbain Curovic, Viktor; Tofte, Nete; Lindhardt, Morten; Adamova, Katarina; Bakker, Stephan J.L.; Beige, Joachim; Beulens, Joline W.J.; Birkenfeld, Andreas L.; Currie, Gemma; Delles, Christian; Dimos, Ingo; Francová, Lidmila; Frimodt-Møller, Marie; Girman, Peter; Göke, Rüdiger; Hansen, Tine W.; Havrdova, Tereza; Kooy, Adriaan; Laverman, Gozewijnw D.; Mischak, Harald; Navis, Gerjan; Nijpels, Giel; Noutsou, Marina; Ortiz, Alberto; Parvanova, Aneliya; Persson, Frederik; Petrie, John R.; Ruggenenti, Piero L.; Rutters, Femke; Rychlík, Ivan; Siwy, Justyna; Spasovski, Goce; Speeckaert, Marijn; Trillini, Matias; Zürbig, Petra; von der Leyen, Heiko; Rossing, Peter; on the behalf of the PRIORITY Study Group (Elsevier, 2023-04)
    Aims: Baseline diabetic retinopathy (DR) and risk of development of microalbuminuria, kidney function decline, and cardiovascular events (CVEs) in type 2 diabetes. Methods: Post-hoc analysis of the PRIORITY study including ...
  • Hypertension and diabetes control: faith-based centres offer a promise for expanding screening services and linkage to care in Ghana 
    Nonterah, Engelbert A.; Chatio, Samuel T.; Willis, Andy; Alale, Joseph A.; Zakariah-Akoto, Sawudatu; Darko, Natalie; Curtis, Ffion; Kunutsor, Setor K.; Jones, Ceri; Seidu, Samuel; Ansah, Patrick O. (BioMed Central Ltd., 2024-10-24)
    BACKGROUND: Hypertension and type 2 diabetes mellitus (T2DM) are important contributors to noncommunicable disease related morbidity and mortality. Health systems could benefit from exploring the use of Faith-Based Centres ...
  • Mechansm study of structural functonal dual bommetc composte bone scaffold for repar of mandbular defects n rabbts 
    Hu, Jiaqi; Zhu, Hong; He, Chongqing; Liu, Xiaochuan; Man, Kenny; Liang, Shanqin; Zhang, Jingying (Whioce Publishing Pte. Ltd, 2024-08-16)
    The present study amsto explore the potental mechansms of bonetssue-engneered trply perodc mnmal surfaces (TPMS) scaffolds contanng njectable plateletrch fibrn and stromal cell-derved factor-1 (n short, SIT scaffolds) n ...
  • Association of busulfan exposure and outcomes after HCT for patients with an inborn error of immunity 
    Bognàr, Tim; Garcia-Rosa, Moises; Lalmohamed, Arief; Güngör, Tayfun; Hauri-Hohl, Mathias; Prockop, Susan; Oram, Layne; Pai, Sung Yun; Brooks, Jordan; Savic, Rada M.; Dvorak, Christopher C.; Long-Boyle, Janel R.; Krajinovic, Maja; Bittencourt, Henrique; Teyssier, Anne Charlotte; Théoret, Yves; Martinez, Cary; Egberts, Toine C.G.; Morales, Erin; Slatter, Mary; Cuvelier, Geoffrey D.E.; Chiesa, Robert; Wynn, Robert F.; Coussons, Mary; Cicalese, Maria P.; Ansari, Marc; Long, Susan E.; Ebens, Christen L.; Lust, Hannah; Chaudhury, Sonali; Nath, Christa E.; Shaw, Peter J.; Keogh, Steven J.; van der Stoep, M. Y.C.Eileen; Bredius, Robbert; Lindemans, Caroline A.; Boelens, Jaap Jan; Bartelink, Imke H. (The American Society of Hematology, 2024-10-08)
    Allogeneic hematopoietic cell transplantation (HCT) is a potentially curative treatment strategy for patients with inborn errors of immunities (IEIs). The objective of this study was to assess the optimal busulfan exposure ...
  • MARK2 variants cause autism spectrum disorder via the downregulation of WNT/β-catenin signaling pathway 
    Gong, Maolei; Li, Jiayi; Qin, Zailong; Machado Bressan Wilke, Matheus Vernet; Liu, Yijun; Li, Qian; Liu, Haoran; Liang, Chen; Morales-Rosado, Joel A.; Cohen, Ana S.A.; Hughes, Susan S.; Sullivan, Bonnie R.; Waddell, Valerie; van den Boogaard, Marie José H.; van Jaarsveld, Richard H.; van Binsbergen, Ellen; van Gassen, Koen L.; Wang, Tianyun; Hiatt, Susan M.; Amaral, Michelle D.; Kelley, Whitley V.; Zhao, Jianbo; Feng, Weixing; Ren, Changhong; Yu, Yazhen; Boczek, Nicole J.; Ferber, Matthew J.; Lahner, Carrie; Elliott, Sherr; Ruan, Yiyan; Mignot, Cyril; Keren, Boris; Xie, Hua; Wang, Xiaoyan; Popp, Bernt; Zweier, Christiane; Piard, Juliette; Coubes, Christine; Mau-Them, Frederic Tran; Safraou, Hana; Innes, A. Micheil; Gauthier, Julie; Michaud, Jacques L.; Koboldt, Daniel C.; Sylvie, Odent; Willems, Marjolaine; Tan, Wen Hann; Cogne, Benjamin; Rieubland, Claudine; Braun, Dominique; McLean, Scott Douglas; Platzer, Konrad; Zacher, Pia; Oppermann, Henry; Evenepoel, Lucie; Blanc, Pierre; El Khattabi, Laïla; Haque, Neshatul; Dsouza, Nikita R.; Zimmermann, Michael T.; Urrutia, Raul; Klee, Eric W.; Shen, Yiping; Du, Hongzhen; Rappaport, Leonard; Liu, Chang Mei; Chen, Xiaoli (Cell Press, 2024-11-07)
    Microtubule affinity-regulating kinase 2 (MARK2) contributes to establishing neuronal polarity and developing dendritic spines. Although large-scale sequencing studies have associated MARK2 variants with autism spectrum ...
  • The intra- and interobserver variability of PSMA-expression scores in patients with primary prostate cancer 
    Donswijk, Maarten L.; Ettema, Rosemarijn H.; van der Gaag, Suzanne; Wondergem, Maurits; Cheung, Zing; van der Poel, Henk G.; Vis, André N.; Oprea-Lager, Daniela E. (Springer Berlin, 2024-10-24)
  • Disparities in management of symptomatic osteoporotic vertebral compression fractures: a nationwide multidisciplinary survey 
    Weber, A.; Vercoulen, T.F.G.; Jacobs, E.; Buizer, A. T.; Bours, S. P.G.; van den Bergh, J. P.; Jeuken, R. M.; van Kuijk, S. M.J.; Evers, S. M.A.A.; Willems, P. C. (Springer London, 2024-10-23)
    Summary : This nationwide multidisciplinary survey found dissatisfaction among physicians with current osteoporotic vertebral compression fracture care, revealing significant disparities in diagnosis, treatment, and follow-up ...
  • Performance of the Aptis distal radioulnar joint implant: kinematic and geometric analysis 
    Oonk, Joris G.M.; Stougie, Shirley D.; Dobbe, Johannes G.G.; Ritt, Marco J.P.F.; Coert, J. Henk; Streekstra, Geert J. (SAGE Publications Ltd, 2025-03)
    This study reviews the performance of the Aptis distal radioulnar joint arthroplasty by comparing multiple kinematic and geometric measurements in the operated and contralateral healthy forearm to elucidate whether these ...
  • A comprehensive transcriptome characterization of individual nuclear receptor pathways in the human small intestine 
    Willemsen, Sam; Yengej, Fjodor A Yousef; Puschhof, Jens; Rookmaaker, Maarten B; Verhaar, Marianne C; van Es, Johan; Beumer, Joep; Clevers, Hans (National Academy of Sciences, 2024-11-05)
    Nuclear receptors (NRs) are widely expressed transcription factors that bind small, lipophilic compounds and regulate diverse biological processes. In the small intestine, NRs are known to act as sensors that control ...
  • Evaluation and management of hepatic dysfunction, portal hypertension and portal/splanchnic vein thrombosis in patients with myelofibrosis undergoing allogeneic haematopoietic cell transplantation: A practice based survey on behalf of the Chronic Malignancies Working Party of the EBMT 
    Battipaglia, Giorgia; Polverelli, Nicola; Tuffnell, Joe; Chiusolo, Patrizia; Robin, Marie; Gambella, Massimiliano; Broers, Annoek; Sala, Elisa; Passweg, Jakob; Furst, Sabine; Friis, Lone Smidtrup; Dulery, Remy; de Witte, Moniek; Srour, Micha; Finazzi, Maria Chiara; Wehr, Claudia; Nagler, Arnon; Richardson, Deborah; Bethge, Wolfgang; Clark, Andrew; Drozd-Sokolowska, Joanna; Raj, Kavita; Czerw, Tomasz; Hernández-Boluda, Juan Carlos; McLornan, Donal P. (2025-01-01)
    Heterogeneous approaches exist in regard to the management of disease-related co-morbidities in potential allogeneic haematopoietic cell transplantation (allo-HCT) candidates with myelofibrosis (MF). The EBMT Chronic ...
  • Cerebral small vessel disease and its relationship with all-cause mortality risk: Results from the Amsterdam Ageing cohort 
    Wiersinga, Julia H.I.; Diab, Hadil M.; Peters, Mike J.L.; Trappenburg, Marijke C.; Rhodius-Meester, Hanneke F.M.; Muller, Majon (Elsevier Ireland Ltd, 2025-02)
    Introduction: Cerebral Small-Vessel Disease (CSVD) is a complex condition affecting the brain's vascular network, linked to cognitive and physical decline, cerebrovascular disease, and death. This study assesses the ...