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UMC Repository: Recent submissions

  • Delineating associations of progressive pleuroparenchymal fibroelastosis in patients with pulmonary fibrosis 
    Gudmundsson, Eyjolfur; Zhao, An; Mogulkoc, Nesrin; van Beek, Frouke; Goos, Tinne; Brereton, Christopher J.; Veltkamp, Marcel; Chapman, Robert; van Es, Hendrik W.; Garthwaite, Helen; Gholipour, Bahareh; Heightman, Melissa; Nair, Arjun; Pontoppidan, Katarina; Savas, Recep; Ahmed, Asia; Vermant, Marie; Unat, Omer; Procter, Alex; De Sadeleer, Laurens; Denneny, Emma; Wallis, Timothy; Duncan, Mark; Taylor, Magali; Verleden, Stijn; Janes, Sam M.; Alexander, Daniel C.; Wells, Athol U.; Porter, Joanna; Jones, Mark G.; Stewart, Iain; van Moorsel, Coline H.M.; Wuyts, Wim; Jacob, Joseph (European Respiratory Society, 2023-03-01)
    Background Computer quantification of baseline computed tomography (CT) radiological pleuroparenchymal fibroelastosis (PPFE) associates with mortality in idiopathic pulmonary fibrosis (IPF). We examined mortality associations ...
  • International spinal cord injury socio-demographic basic data set (version 1.0) 
    Chen, Yuying; Charlifue, Susan; Noonan, Vanessa K.; New, Peter W.; Gururaj, Gopalkrishna; Katoh, Shinsuke; Leiulfsrud, Håkon; Post, Marcel W.; Biering-Sørensen, Fin (Springer Nature, 2023-05)
    Study design: Consensus based on the literature. Objective: Create an International Spinal Cord Injury (SCI) Socio-Demographic Basic Data Set (Version 1.0). Setting: International. Methods: The development included an ...
  • Acceleration of GABA-switch after early life stress changes mouse prefrontal glutamatergic transmission 
    Karst, Henk; Droogers, Wouter J.; van der Weerd, Nelleke; Damsteegt, Ruth; van Kroonenburg, Nicky; Sarabdjitsingh, R. Angela; Joëls, Marian (Elsevier Limited, 2023-08-15)
    Early life stress (ELS) alters the excitation-inhibition-balance (EI-balance) in various rodent brain areas and may be responsible for behavioral impairment later in life. The EI-balance is (amongst others) influenced by ...
  • In vivo generation of thrombin in patients with liver disease without apparent evidence of activation of the intrinsic or extrinsic pathway of coagulation 
    Elvers, Fynn L.; Stamouli, Marilena; Adelmeijer, Jelle; Jeyanesan, Dhaarica; Bernal, William; Maas, Coen; Patel, Vishal C.; Lisman, Ton (Wiley-Blackwell, 2023-08)
    Background: Patients with liver diseases are in a hypercoagulable state, as evidenced by enhanced in vitro thrombin generating capacity and elevated plasma levels of markers of in vivo thrombin generation. However, it is ...
  • Validity of Early Outcomes as Indicators for Comparing Hospitals on Quality of Stroke Care 
    Amini, Marzyeh; Eijkenaar, Frank; Lingsma, Hester F.; Den Hartog, Sanne J.; Olthuis, Susanne G.H.; Martens, Jasper; van der Worp, Bart; van Zwam, Wim; van der Hoorn, Anouk; Roosendaal, Stefan D.; Roozenbeek, Bob; Dippel, Diederik; van Leeuwen, Nikki; MR CLEAN Registry Investigators (Wiley-Blackwell, 2023-04-18)
    BACKGROUND: Insight into outcome variation between hospitals could help to improve quality of care. We aimed to assess the validity of early outcomes as quality indicators for acute ischemic stroke care for patients treated ...
  • Recommendations on diagnosis and antimicrobial treatment of infections after anterior cruciate ligament reconstruction (ACL-R) endorsed by ESSKA and EBJIS 
    Renz, Nora; Madjarevic, Tomislav; Ferrari, Matteo; Becker, Roland; Ravn, Christen; Vogely, Charles; Pérez-Prieto, Daniel (W.B. Saunders Ltd, 2023-06)
    Infection after anterior cruciate ligament reconstruction (ACL-R) is a rare but devastating complication affecting predominantly young and sportive individuals. A timely and correct diagnosis as well as optimized management ...
  • Impact of coronary artery disease on clinical outcomes after TAVR: Insights from the BRAVO-3 randomized trial 
    Feldman, Daniel; Cao, Davide; Sartori, Samantha; Zhang, Zhongjie; Hengstenberg, Christian; Tron, Christophe; Anthopoulos, Prodromos; Widder, Julian D.; Meneveau, Nicolas; Stella, Pieter R.; Ferrari, Markus; Jeger, Raban; Violini, Roberto; Dumonteil, Nicolas; Chen, Shiwei; Yan, Ruiqi; Nicolas, Johny; Razuk, Victor; Spirito, Alessandro; Vogel, Birgit; Mehran, Roxana; Dangas, George (John Wiley & Sons Inc., 2023-05-01)
    Objective: To determine the prognostic impact of coronary artery disease (CAD) in patients randomized to bivalirudin or unfractionated heparin (UFH) during transcatheter aortic valve replacement (TAVR). Background: CAD is ...
  • Comparing genomic variant identification protocols for Candida auris 
    Li, Xiao; Muñoz, José F.; Gade, Lalitha; Argimon, Silvia; Bougnoux, Marie Elisabeth; Bowers, Jolene R.; Chow, Nancy A.; Cuesta, Isabel; Farrer, Rhys A.; Maufrais, Corinne; Monroy-Nieto, Juan; Pradhan, Dibyabhaba; Uehling, Jessie; Vu, Duong; Yeats, Corin A.; Aanensen, David M.; D’enfert, Christophe; Engelthaler, David M.; Eyre, David W.; Fisher, Matthew C.; Hagen, Ferry; Meyer, Wieland; Singh, Gagandeep; Alastruey-Izquierdo, Ana; Litvintseva, Anastasia P.; Cuomo, Christina A. (Microbiology Society, 2023-04)
    Genomic analyses are widely applied to epidemiological, population genetic and experimental studies of pathogenic fungi. A wide range of methods are employed to carry out these analyses, typically without including controls ...
  • Exploring the Sentence Length and Age of Acquisition of Speech Recognition Test Sentences in Dutch, American English, and Canadian French 
    van der Hoek-Snieders, Hanneke E.M.; Rhebergen, Koenraad S. (American Speech-Language-Hearing Association (ASHA), 2023-04)
    Purpose: The purpose of this study was to examine the differences betthe age of acquisition (AoA) and sentence length of sentences of the srecognition (SR) tests for adults and children in Dutch, American English, Canadian ...
  • Internal Fixation of Unstable Osteochondritis Dissecans of the Knee: Long-term Outcomes in Skeletally Immature and Mature Patients 
    Husen, Martin; Van der Weiden, Goran S.; Custers, Roel J.H.; Poudel, Keshav; Stuart, Michael J.; Krych, Aaron J.; Saris, Daniël B.F. (SAGE Publications Inc., 2023-05)
    Background: Osteochondritis dissecans (OCD) is a disorder originating in the subchondral bone, leading to focal lesions with risk of fragmentation and secondary damage of the articular cartilage. It remains controversial ...
  • Medial Patellofemoral Ligament Reconstruction Using Allografts in Skeletally Immature Patients 
    Husen, Martin; Milbrandt, Todd A.; Shah, Veeraj; Krych, Aaron J.; Stuart, Michael J.; Saris, Daniel B.F. (SAGE Publications Inc., 2023-05)
    Background: Patellar instability has the highest incidence in adolescents aged between 14 and 18 years. The unique relationship between the medial patellofemoral ligament (MPFL) and the distal femoral physis in skeletally ...
  • Trends in molecular diagnostics: 12th European Meeting on Molecular Diagnostics, Noordwijk aan Zee, the Netherlands, 12-14 October 2022 
    Loonen, Anne J.M.; Schuurman, Rob; van den Brule, Adriaan J.C. (Taylor and Francis Ltd., 2023-04)
    This report provides an overview of the highlights of the 12th European Meeting on Molecular Diagnostics held in Noordwijk aan Zee, The Netherlands, 12–14 October 2022. This 3-day conference covered many relevant topics ...
  • PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial 
    Voorwerk, Leonie; Isaeva, Olga I.; Horlings, Hugo M.; Balduzzi, Sara; Chelushkin, Maksim; Bakker, Noor A.M.; Champanhet, Elisa; Garner, Hannah; Sikorska, Karolina; Loo, Claudette E.; Kemper, Inge; Mandjes, Ingrid A.M.; de Maaker, Michiel; van Geel, Jasper J.L.; Boers, Jorianne; de Boer, Maaike; Salgado, Roberto; van Dongen, Marloes G.J.; Sonke, Gabe S.; de Visser, Karin E.; Schumacher, Ton N.; Blank, Christian U.; Wessels, Lodewyk F.A.; Jager, Agnes; Tjan-Heijnen, Vivianne C.G.; Schröder, Carolien P.; Linn, Sabine C.; Kok, Marleen (Nature Research, 2023-04)
    Invasive lobular breast cancer (ILC) is the second most common histological breast cancer subtype, but ILC-specific trials are lacking. Translational research revealed an immune-related ILC subset, and in mouse ILC models, ...
  • Estimation of Respiratory Rate during Biking with a Single Sensor Functional Near-Infrared Spectroscopy (fNIRS) System 
    Shahbakhti, Mohammad; Hakimi, Naser; Horschig, Jörn M.; Floor-Westerdijk, Marianne; Claassen, Jurgen; Colier, Willy N.J.M. (Multidisciplinary Digital Publishing Institute (MDPI), 2023-04)
    Objective: The employment of wearable systems for continuous monitoring of vital signs is increasing. However, due to substantial susceptibility of conventional bio-signals recorded by wearable systems to motion artifacts, ...
  • Cost-effectiveness of a new ACI technique for the treatment of articular cartilage defects of the knee compared to regularly used ACI technique and microfracture 
    Snow, Martyn; Mandalia, Vipul; Custers, Roel; Emans, Pieter J.; Kon, Elizaveta; Niemeyer, Philipp; Verdonk, René; Gaissmaier, Christoph; Roeder, André; Weinand, Sina; Zöllner, York; Schubert, Tino (Informa Healthcare, 2023)
    Aims: For patients with cartilage defects of the knee, a new biocompatible and in situ cross-linkable albumin-hyaluronan-based hydrogel has been developed for matrix-associated autologous chondrocyte implantation ...
  • Single-cell T cell receptor sequencing of paired human atherosclerotic plaques and blood reveals autoimmune-like features of expanded effector T cells 
    Depuydt, Marie A.C.; Schaftenaar, Frank H.; Prange, Koen H.M.; Boltjes, Arjan; Hemme, Esmeralda; Delfos, Lucie; de Mol, Jill; de Jong, Maaike J.M.; Bernabé Kleijn, Mireia N.A.; Peeters, Judith A.H.M.; Goncalves, Lauren; Wezel, Anouk; Smeets, Harm J.; de Borst, Gert J.; Foks, Amanda C.; Pasterkamp, Gerard; de Winther, Menno P.J.; Kuiper, Johan; Bot, Ilze; Slütter, Bram (Nature Publishing Group, 2023-02)
    Atherosclerosis is a lipid-driven chronic inflammatory disease; however, whether it can be classified as an autoimmune disease remains unclear. In this study, we applied single-cell T cell receptor seqencing (scTCR-seq) ...
  • Protocol compliance in a multicentric phase III trial investigating scheduled adaptive radiotherapy and dose painting in head and neck cancer 
    de Leeuw, Anna Liza M.P.; Giralt, Jordi; Tao, Yungan; Benavente, Sergi; Nguyen, Thanh Vân F.; Hoebers, Frank J.P.; Hoeben, Ann; Terhaard, Chris H.J.; Lee, Lip Wai; Friesland, Signe; Steenbakkers, Roel J.H.M.; Tans, Lisa; van Kranen, Simon R.; van de Kamer, Jeroen B.; Bartelink, Harry; Rasch, Coen R.N.; Sonke, Jan Jakob; Hamming-Vrieze, Olga (Elsevier Ireland Ltd, 2025-01)
    Purpose: To report on quality assurance (QA) and protocol adherence (PA) in a multicentre phase III trial for head and neck cancer, evaluate patterns of protocol deviations and investigate the effect of PA on study outcomes. ...
  • Psychometric properties of the English language version of the C-BiLLT evaluated in typically developing Canadian children 
    Bootsma, Jael N.; Campbell, Fiona; McCauley, Dayle; Hopmans, Sarah; Grahovac, Danijela; Cunningham, B. J.; Phoenix, Michelle; De Camargo, Olaf Kraus; Geytenbeek, Johanna; Gorter, Jan Willem (IOS Press, 2023)
    PURPOSE: This study aimed to 1) investigate the convergent and discriminant validity, internal consistency, and test-retest reliability of the Canadian English version of the Computer-Based instrument for Low motor Language ...
  • Neurocognitive, Psychosocial, and Quality of Life Outcomes After Multisystem Inflammatory Syndrome in Children Admitted to the PICU 
    Otten, Marieke H.; Buysse, Corinne M.P.; Buddingh, Emmeline P.; Terheggen-Lagro, Suzanne W.J.; Von Asmuth, Erik G.J.; De Sonnaville, Eleonore S.V.; Ketharanathan, Naomi; Bunker-Wiersma, Heleen E.; Haverman, Lotte; Hogenbirk, Karin; De Hoog, Matthijs; Humblet, Martien; Joosten, Koen F.M.; Kneyber, Martin C.J.; Krabben, Geanne; Lemson, Joris; Maas, Nienke M.; Maebe, Sofie; Roeleveld, Peter P.; Van Schooneveld, Monique; Timmers-Raaijmaakers, Brigitte; Van Waardenburg, Dick; Walker, Jennifer C.; Wassenberg, Renske; Van Woensel, Job B.M.; De Wit, Esther; Wolthuis, Diana W.; Van Zwol, Annelies; Oostrom, Kim J.; Knoester, Hennie; Dulfer, Karolijn (Lippincott Williams & Wilkins, 2023-04-01)
    OBJECTIVES: To investigate neurocognitive, psychosocial, and quality of life (QoL) outcomes in children with Multisystem Inflammatory Syndrome in Children (MIS-C) seen 3-6 months after PICU admission. DESIGN: National ...
  • Therapeutic potential of minor cannabinoids in psychiatric disorders: A systematic review 
    Cammà, Guido; Verdouw, Monika P.; van der Meer, Pim B.; Groenink, Lucianne; Batalla, Albert (Elsevier, 2025-02)
    Interest in cannabinoids’ therapeutic potential in mental health is growing, supported by evidence of the involvement of the endocannabinoid system in psychiatric disorders such as anxiety, depression, and addiction. While ...