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UMC Repository: Recent submissions

  • Candida parapsilosis isolates carrying mutations outside FKS1 hotspot regions confer high echinocandin tolerance and facilitate the development of echinocandin resistance 
    Daneshnia, Farnaz; Arastehfar, Amir; Lombardi, Lisa; Binder, Ulrike; Scheler, Jakob; Vahedi Shahandashti, Roya; Hagen, Ferry; Lass-Flörl, Cornelia; Mansour, Michael K.; Butler, Geraldine; Perlin, David S. (Elsevier, 2023-07)
    Candida parapsilosis is a significant cause of candidemia worldwide. Echinocandin-resistant (ECR) and echinocandin-tolerant (ECT) C. parapsilosis isolates have been reported in various countries but are rare. Resistance ...
  • Molecular Profile of MSH6-Associated Colorectal Carcinomas Shows Distinct Features From Other Lynch Syndrome–Associated Colorectal Carcinomas 
    Helderman, Noah c.; Van Der Werf-’T Lam, Anne Sophie; Terlouw, Diantha; Bajwa-ten Broeke, Sanne W.; Rodríguez-Girondo, Mar; van Egmond, Demi; Langers, Alexandra M.J.; van Leerdam, Monique E.; Rayner, Emily; van Asperen, Christi J.; van Hest, Liselotte P.; Gille, Hans J.P.; Duijkers, Floor A.M.; Wagner, Anja; Eikenboom, Ellis L.; Letteboer, Tom G.W.; de Jong, Mirjam M.; Bleeker, Fonnet E.; Gomez Garcìa, Encarna B.; Suerink, Manon; Tops, Carli M.; de Wind, Niels; Morreau, Hans; Boot, Arnoud; Van Wezel, Tom; Nielsen, Maartje; MSH6 TUMOR GROUP (W.B. Saunders, 2023-07)
  • Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021 
    Harlianto, Netanja I.; GBD 2021 Low Back Pain Collaborators (Elsevier Limited, 2023-06)
    Background: Low back pain is highly prevalent and the main cause of years lived with disability (YLDs). We present the most up-to-date global, regional, and national data on prevalence and YLDs for low back pain from the ...
  • Combining automatic speech recognition with semantic natural language processing in schizophrenia 
    Ciampelli, S.; Voppel, A. E.; de Boer, J. N.; Koops, S.; Sommer, I. E.C. (Elsevier Ireland Ltd, 2023-07)
    Natural language processing (NLP) tools are increasingly used to quantify semantic anomalies in schizophrenia. Automatic speech recognition (ASR) technology, if robust enough, could significantly speed up the NLP research ...
  • Dysregulation of miRNA-30e-3p targeting IL-1β in an international cohort of systemic autoinflammatory disease patients 
    Akbaba, Tayfun Hilmi; Akkaya-Ulum, Yeliz Z.; Batu, Ezgi Deniz; Penco, Federica; Wittkowski, Helmut; Kant, Benjamin; van Gijn, Marielle E.; Foell, Dirk; Gattorno, Marco; Ozen, Seza; Balci-Peynircioglu, Banu (Springer-Verlag, 2023-06)
    Abstract: Autoinflammation is the standard mechanism seen in systemic autoinflammatory disease (SAID) patients. This study aimed to investigate the effect of a candidate miRNA, miR-30e-3p, which was identified in our ...
  • The Dutch Working Party on Antibiotic Policy (SWAB) guideline for the approach to suspected antibiotic allergy 
    Wijnakker, Roos; van Maaren, Maurits S.; Bode, Lonneke G.M.; Bulatovic, Maja; Hendriks, Bart J.C.; Loogman, Masja C.M.; Lutgens, Suzanne P.M.; Middel, Ananja; Nieuwhof, Chris M.G.; Roelofsen, Eveline E.; Schoones, Jan W.; Sigaloff, Kim C.E.; Sprikkelman, Aline B.; de Vrankrijker, Lieke M.M.; de Boer, Mark G.J. (Elsevier, 2023-07)
    Objectives: Prudent handling of reported antibiotic allergies is an important aspect of antibiotic stewardship. The Dutch Working Party on Antibiotic Policy (SWAB) constituted a multidisciplinary expert committee to provide ...
  • Efficacy and Safety of Abrocitinib in Patients with Severe and/or Difficult-to-Treat Atopic Dermatitis: A Post Hoc Analysis of the Randomized Phase 3 JADE COMPARE Trial 
    Simpson, Eric L.; Silverberg, Jonathan I.; Thyssen, Jacob P.; Viguier, Manuelle; Thaçi, Diamant; de Bruin-Weller, Marjolein; Weidinger, Stephan; Chan, Gary; DiBonaventura, Marco; Biswas, Pinaki; Feeney, Claire; Koulias, Christopher; Cork, Michael J. (Adis, 2023-07)
    Background: Traditional systemic immunosuppressants and advanced therapies improve signs and symptoms of moderate-to-severe atopic dermatitis (AD). However, data are limited in severe and/or difficult-to-treat AD. In the ...
  • Identifying distinct clinical clusters in heart failure with mildly reduced ejection fraction 
    Meijs, Claartje; Brugts, Jasper J.; Lund, Lars H.; Linssen, Gerard C.M.; Rocca, Hans Peter Brunner La; Dahlström, Ulf; Vaartjes, Ilonca; Koudstaal, Stefan; Asselbergs, Folkert W.; Savarese, Gianluigi; Uijl, Alicia (Elsevier Ireland Ltd, 2023-09-01)
    Introduction: Heart failure (HF) is a heterogeneous syndrome, and the specific sub-category HF with mildly reduced ejection fraction (EF) range (HFmrEF; 41–49% EF) is only recently recognised as a distinct entity. Cluster ...
  • Gebeten door een pup uit Oekraïne 
    Overgaauw, Paul; van Uum, Rick (Bohn Stafleu van Loghum, 2023-05)
    Rabiës komt wereldwijd nog veel voor. Manifeste infecties zijn vrijwel altijd dodelijk en daarom is adequate preventie van cruciaal belang. In deze bijdrage bespreken we de belangrijkste aandachtspunten voor u als huisarts: ...
  • Retrospective Multicenter Evaluation of the VirClia Galactomannan Antigen Assay for the Diagnosis of Pulmonary Aspergillosis with Bronchoalveolar Lavage Fluid Samples from Patients with Hematological Disease 
    Buil, Jochem B.; Huygens, Sammy; Dunbar, Albert; Schauwvlieghe, Alexander; Reynders, Marijke; Langerak, Diana; van Dijk, Karin; Bruns, Anke; Haas, Pieter Jan; Postma, Douwe F.; Biemond, Bart; Delma, Fatima Zohra; de Kort, Elizabeth; Melchers, Willem J.G.; Verweij, Paul E.; Rijnders, Bart; the Dutch-Belgian Mycosis Study Group (American Society for Microbiology, 2023-05)
    Galactomannan (GM) testing of bronchoalveolar lavage (BAL) fluid samples has become an essential tool to diagnose invasive pulmonary aspergillosis (IPA) and is part of diagnostic guidelines. Enzyme-linked immunosorbent ...
  • The big picture: Mary Dallman, a role model 
    Joëls, Marian (Informa Healthcare, 2023-01)
    Mary Dallman has left a legacy in neuroendocrinology, not only as the scientist who elaborated on new concepts such as rapid corticosteroid feedback pathways, but also as a role model, particularly for women who followed ...
  • Receptor Density-Dependent Motility of Influenza Virus Particles on Surface Gradients 
    Hamming, P. H.Erik; Overeem, Nico J.; Diestelhorst, Kevin; Fiers, Tren; Tieke, Malte; Vos, Gaël M.; Boons, Geert Jan P.H.; Van Der Vries, Erhard; Block, Stephan; Huskens, Jurriaan (American Chemical Society, 2023-05-24)
    Influenza viruses can move across the surface of host cells while interacting with their glycocalyx. This motility may assist in finding or forming locations for cell entry and thereby promote cellular uptake. Because the ...
  • Phospholamban R14del disease: The past, the present and the future 
    Vafiadaki, Elizabeth; Glijnis, Pieter C.; Doevendans, Pieter A.; Kranias, Evangelia G.; Sanoudou, Despina (Frontiers Media S. A., 2023)
    Arrhythmogenic cardiomyopathy affects significant number of patients worldwide and is characterized by life-threatening ventricular arrhythmias and sudden cardiac death. Mutations in multiple genes with diverse functions ...
  • Age-associated systemic factors change central and peripheral immunity in adult male mice 
    van Olst, L.; Kamermans, A.; van der Pol, S. M.A.; Rodríguez, E.; Hulshof, L. A.; van Dijk, R. E.; Vonk, D. N.; Schouten, M.; Witte, M. E.; de Vries, H. E.; Middeldorp, J. (Academic Press Inc., 2023-07)
    Aging coincides with major changes in brain immunity that aid in a decline in neuronal function. Here, we postulate that systemic, pro-aging factors contribute to immunological changes that occur within the brain during ...
  • Efficacy of immune checkpoint inhibitors in microsatellite unstable/mismatch repair-deficient advanced pancreatic adenocarcinoma: an AGEO European Cohort 
    Taïeb, Julien; Sayah, Lina; Heinrich, Kathrin; Kunzmann, Volker; Boileve, Alice; Cirkel, Geert; Lonardi, Sara; Chibaudel, Benoist; Turpin, Anthony; Beller, Tamar; Hautefeuille, Vincent; Vivaldi, Caterina; Mazard, Thibault; Bauguion, Lucile; Niger, Monica; Prager, Gerald W.; Coutzac, Clelia; Benedikt Westphalen, C.; Auclin, Edouard; Pilla, Lorenzo (Elsevier Limited, 2023-07)
    Background: Immune checkpoint inhibitors (ICIs) improve oncological outcomes in patients with microsatellite instability-high (MSI) or mismatch repair-deficient (dMMR) advanced solid tumours. Nevertheless, based on limited ...
  • Multifunctional nanostructures: Intelligent design to overcome biological barriers 
    Azizi, Mehdi; Jahanban-Esfahlan, Rana; Samadian, Hadi; Hamidi, Masoud; Seidi, Khaled; Dolatshahi-Pirouz, Alireza; Yazdi, Amirhossein Ahmadieh; Shavandi, Amin; Laurent, Sophie; Be Omide Hagh, Mahsa; Kasaiyan, Nahid; Santos, Hélder A.; Shahbazi, Mohammad Ali (Elsevier, 2023-06)
    Over the past three decades, nanoscience has offered a unique solution for reducing the systemic toxicity of chemotherapy drugs and for increasing drug therapeutic efficiency. However, the poor accumulation and pharmacokinetics ...
  • Computer-Assisted Surgical Anatomical Mapping of the Antebrachial Cutaneous Nerves: An Anatomical Study with a Proposition for Alternative, Cutaneous Nerve-Sparing Anterior Elbow Incisions 
    Langenberg, Lisette C.; Poublon, Alexander R.; Hofman, Lieke; Kleinrensink, Gert Jan; Eygendaal, Denise (Lippincott Williams & Wilkins, 2023-05-15)
    Background:It is common practice to assess the distance from nerves to anatomical structures in centimeters, but patients have various body compositions and anatomical variations are common. The purpose of this study was ...
  • Human and chimpanzee shared and divergent neurobiological systems for general and specific cognitive brain functions 
    van den Heuvel, Martijn P.; Ardesch, Dirk Jan; Scholtens, Lianne H.; de Lange, Siemon C.; van Haren, Neeltje E.M.; Sommer, Iris E.C.; Dannlowski, Udo; Repple, Jonathan; Preuss, Todd M.; Hopkins, William D.; Rilling, James K. (National Academy of Sciences, 2023-05-30)
    A long-standing topic of interest in human neurosciences is the understanding of the neurobiology underlying human cognition. Less commonly considered is to what extent such systems may be shared with other species. We ...
  • Sex-based differences in cardiovascular proteomic profiles and their associations with adverse outcomes in patients with chronic heart failure 
    de Bakker, Marie; Petersen, Teun B.; Akkerhuis, K. Martijn; Harakalova, Magdalena; Umans, Victor A.; Germans, Tjeerd; Caliskan, Kadir; Katsikis, Peter D.; van der Spek, Peter J.; Suthahar, Navin; de Boer, Rudolf A.; Rizopoulos, Dimitris; Asselbergs, Folkert W.; Boersma, Eric; Kardys, Isabella (BioMed Central, 2023-12)
    Background: Studies focusing on sex differences in circulating proteins in patients with heart failure with reduced ejection fraction (HFrEF) are scarce. Insight into sex-specific cardiovascular protein profiles and their ...
  • Primary SARS-CoV-2 infection in patients with immune-mediated inflammatory diseases: long-term humoral immune responses and effects on disease activity 
    van Dam, Koos P.J.; Volkers, Adriaan G.; Wieske, Luuk; Stalman, Eileen W.; Kummer, Laura Y.L.; van Kempen, Zoé L.E.; Killestein, Joep; Tas, Sander W.; Boekel, Laura; Wolbink, Gerrit J.; van der Kooi, Anneke J.; Raaphorst, Joost; Takkenberg, R. Bart; D’Haens, Geert R.A.M.; Spuls, Phyllis I.; Bekkenk, Marcel W.; Musters, Annelie H.; Post, Nicoline F.; Bosma, Angela L.; Hilhorst, Marc L.; Vegting, Yosta; Bemelman, Frederike J.; Voskuyl, Alexandre E.; Broens, Bo; Sanchez, Agner Parra; van Els, Cécile A.C.M.; de Wit, Jelle; Rutgers, Abraham; de Leeuw, Karina; Horváth, Barbara; Verschuuren, Jan J.G.M.; Ruiter, Annabel M.; van Ouwerkerk, Lotte; van der Woude, Diane; Allaart, Renée C.F.; Teng, Y. K.Onno; van Paassen, Pieter; Busch, Matthias H.; Jallah, Papay B.P.; Brusse, Esther; van Doorn, Pieter A.; Baars, Adája E.; Hijnen, Dirk Jan; Schreurs, Corine R.G.; van der Pol, W. Ludo; Goedee, H. Stephan; Steenhuis, Maurice; Keijzer, Sofie; Keijser, Jim B.D.; Cristianawati, Olvi; on behalf of the T2B! Immunity against SARS-CoV-2 study group (BioMed Central, 2023-12)
    Background: Patients with immune-mediated inflammatory diseases (IMIDs) on immunosuppressants (ISPs) may have impaired long-term humoral immune responses and increased disease activity after SARS-CoV-2 infection. We aimed ...