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  • Reply - Letter to the editor entitled “Letter to editor - Dietary and lifestyle inflammation scores in relation to colorectal cancer recurrence and all-cause mortality: A longitudinal analysis” 
    Wesselink, Evertine; Boshuizen, Hendriek C.; van Lanen, Anne Sophie; Kok, Dieuwertje E.; Derksen, Jeroen W.G.; Smit, Karel C.; de Wilt, Johannes H.W.; Koopman, Miriam; May, Anne M.; Kampman, Ellen; van Duijnhoven, Fränzel J.B. (Churchill Livingstone, 2024-12)
  • Colorectal carcinoma progression is not influenced by the pseudokinase PEAK1 
    Zuidema, Alba; Atherton, Paul; van der Poel, Sabine; Kreft, Maaike; Song, Ji Ying; Bierbooms, Martine; Verhoeven, Sophie; Papagianni, Chrysoula; Kroese, Lona; Ali, Rahmen Bin; Huijbers, Ivo; Carvalho, Beatriz; Sonnenberg, Arnoud (Nature Publishing Group, 2024-11-12)
    The scaffold protein PEAK1 acts downstream of integrin adhesion complexes and the epidermal growth factor receptor, orchestrating signaling events that control cell proliferation and cytoskeletal remodeling. In this study ...
  • Three-year mortality of ICU survivors with sepsis, an infection or an inflammatory illness: an individually matched cohort study of ICU patients in the Netherlands from 2007 to 2019 
    Arbous, Sesmu M.; Termorshuizen, Fabian; Brinkman, Sylvia; de Lange, Dylan W.; Bosman, Rob J.; Dekkers, Olaf M.; de Keizer, Nicolette F. (Springer Science + Business Media, 2024-11-19)
    Background: Sepsis is a frequent reason for ICU admission and a leading cause of death. Its incidence has been increasing over the past decades. While hospital mortality is decreasing, it is recognized that the sequelae ...
  • Pembrolizumab for locally advanced cervical cancer 
    Schmid, Maximilian P.; Petric, Primoz; Mahantshetty, Umesh; Kirisits, Christian; Tanderup, Kari; Jürgenliemk-Schulz, Ina; Lindegaard, Jacob; Pötter, Richard (Elsevier, 2024-11-23)
  • Corrigendum: The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort (Frontiers in Neurology, (2023), 14, (1291020), 10.3389/fneur.2023.1291020) 
    Singh, Sanjula D.; Oreskovic, Tin; Carr, Sinclair; Papier, Keren; Conroy, Megan; Senff, Jasper R.; Chemali, Zeina; Gutierrez-Martinez, Leidys; Parodi, Livia; Mayerhofer, Ernst; Marini, Sandro; Nunley, Courtney; Newhouse, Amy; Ouyang, An; Brouwers, H. Bart; Westover, Brandon; Rivier, Cyprien; Falcone, Guido; Howard, Virginia; Howard, George; Pikula, Aleksandra; Ibrahim, Sarah; Sheth, Kevin N.; Yechoor, Nirupama; Lazar, Ronald M.; Anderson, Christopher D.; Tanzi, Rudolph E.; Fricchione, Gregory; Littlejohns, Thomas; Rosand, Jonathan (Frontiers Media S. A., 2024-11-05)
    In the published article Dr. Westover's disclosure statement was inadvertently omitted. The disclosure should read: “BW has private equity as co-founder of Beacon Biosignals and receives compensation for consulting and ...
  • The mediatory role of androgens on sex differences in glucose homeostasis and incidence of type 2 diabetes: the KORA study 
    Raeisi-Dehkordi, Hamidreza; Thorand, Barbara; Beigrezaei, Sara; Peters, Annette; Rathman, Wolfgang; Adamski, Jerzy; Chatelan, Angeline; van der Schouw, Yvonne T.; Franco, Oscar H.; Muka, Taulant; Nano, Jana (BioMed Central, 2024-11-15)
    Background: Sex differences exist in type 2 diabetes (T2D), and androgens have been implicated in the etiology of T2D in a sex-specific manner. We therefore aimed to investigate whether androgens play a role in explaining ...
  • Cardiometabolic risk factors are affected by interaction between FADS1 rs174556 variant and dietary vegetable oils in patients with diabetes: a randomized controlled trial 
    Fallah, Zahra; Vasmehjani, Azam Ahmadi; Aghaei, Shiva; Amiri, Mojgan; Raeisi-Dekordi, Hamidreza; Moghtaderi, Fatemeh; Zimorovat, Alireza; Yazd, Ehsan Farashahi; Madadizadeh, Farzan; Khayyatzadeh, Sayyed Saeid; Salehi-Abargouei, Amin (Nature Publishing Group, 2024-11-11)
    FADS1 rs174556 polymorphism influences on dietary fats metabolism and type 2 diabetes (T2DM). This study aimed to compare the effect of three oils of sesame, canola and sesame-canola on cardio metabolic factors across ...
  • Brain magnetic resonance imaging of patients with spinal muscular atrophy type 2 and 3 
    Stam, Marloes; Tan, Harold H.G.; Schmidt, Ruben; van den Heuvel, Martijn P.; van den Berg, Leonard H.; Wadman, Renske I.; van der Pol, W. Ludo (Elsevier, 2024-11-21)
    Background and objective: Proximal spinal muscular atrophy (SMA) is caused by deficiency of the ubiquitously expressed survival motor neuron protein. Although primarily a hereditary lower motor neuron disease, it is probably ...
  • The Gastroscopy RAte of Cleanliness Evaluation (GRACE) Scale: an international reliability and validation study 
    Esposito, Gianluca; Dilaghi, Emanuele; Costa-Santos, Cristina; Ligato, Irene; Annibale, Bruno; Dinis-Ribeiro, Mário; Areia, Miguel; Arantes, Vitor N.; Bergman, Jacques; Bisschops, Raf; de Jonge, Pieter J.F.; Matteo, Francesco Di; Ebigbo, Alanna; Ferlitsch, Monika; Giljaca, Vanja; Hassan, Cesare; Hucl, Tomas; Kuvaev, Roman; Leclercq, Philippe; Matysiak-Budnik, Tamara; Mori, Yuichi; Moss, Alan; Pérez-Cuadrado-Robles, Enrique; Pouw, Roos E.; Rex, Douglas K.; de Santiago, Enrique Rodriguez; Siersema, Peter D.; Tham, Tony C.; Triantafyllou, Konstantinos; Voiosu, Andrei; Weusten, Bas; Andrisani, Gianluca; Angeletti, Stefano; Ayoub, Mousa; Bac, Simon; Boonstra, Kirsten; Borren, Nienke; Capogreco, Antonio; Martín Falquina, Irene Chivato; Chaves, Jéssica; Citterio, Nicolò; Buono, Arianna Dal; Dell’Unto, Elisabetta; Dragan, Victor; Elvas, Luís; Filimendikova, Ksenia; Frick, Adrian; Guardiola, John; Halvorsen, Natalie; Le Rhun, Marc; Grace Investigators (Georg Thieme Verlag, 2025-04)
    Background Mucosal visualization during upper gastrointestinal (UGI) endoscopy can be impaired by the presence of foam, bubbles, and mucus. Some UGI endoscopy visibility scales have been proposed but have not undergone ...
  • Higher non-HIV-comorbidity burden in long-term survivors 
    Vonder, Thom W.; Mudrikova, Tania (Lippincott Williams & Wilkins, 2025-03-15)
    Objective:The possible differences in comorbidity burden were examined between people with longstanding HIV infection and those with shorter HIV duration of the same calendar age.Design:We performed a single-centre ...
  • Parameningeal Rhabdomyosarcoma: Results of the European Pediatric Soft Tissue Sarcoma Study Group RMS 2005 Study 
    Schoot, Reineke A.; Taselaar, Pieter; Scarzello, Giovanni; Kolb, Frederic; Coppadoro, Beatrice; Horst, Simone ter; Mandeville, Henry; Ferrari, Andrea; Hladun, Raquel; Helfre, Sylvie; Ferman, Sima; Kelsey, Anna; Hol, Marinka L.F.; Devalck, Christine; Ben-Arush, Myriam; Orbach, Daniel; Chisholm, Julia; Jenney, Meriel; Minard-Colin, Veronique; Bisogno, Gianni; Merks, Johannes H.M. (John Wiley & Sons Inc., 2025-03)
    Background: Parameningeal (PM) site is an unfavorable characteristic in rhabdomyosarcoma (RMS). We described the treatment and outcome for patients with PM RMS and investigated the prognostic value of risk factors. We ...
  • Are food and beverage purchases reflective of dietary intake? Validity of supermarket purchases as indicator of diet quality in the Supreme Nudge Trial 
    Colizzi, Chiara; Stuber, Josine M.; Van Der Schouw, Yvonne T.; Beulens, Joline W.J. (Cambridge University Press, 2024-11-28)
    Dietary intake assessment is often complicated by intrinsic bias. This study investigated whether food purchase data could constitute a valid indication of dietary intake, by evaluating the extent to which diet quality as ...
  • Impact of hypertension on mortality in patients with ST-elevation myocardial infarction undergoing primary angioplasty: insights from the international multicenter ISACS-STEMI registry 
    De Luca, Giuseppe; Nardin, Matteo; Algowhary, Magdy; Uguz, Berat; Oliveira, Dinaldo C.; Ganyukov, Vladimir; Zimbakov, Zan; Cercek, Miha; Okkels Jensen, Lisette; Loh, Poay Huan; Calmac, Lucian; Roura I Ferrer, Gerard; Quadros, Alexandre; Milewski, Marek; Scotto D'Uccio, Fortunato; Von Birgelen, Clemens; Versaci, Francesco; Ten Berg, Jurrien; Casella, Gianni; Lung, Aaron Wong Sung; Kala, Petr; Díez Gil, José Luis; Carrillo, Xavier; Dirksen, Maurits; Becerra-Munoz, Victor M.; Lee, Michael Kang Yin; Juzar, Dafsah Arifa; De Moura Joaquim, Rodrigo; Paladino, Roberto; Milicic, Davor; Davlouros, Periklis; Bakraceski, Nikola; Zilio, Filippo; Donazzan, Luca; Kraaijeveld, Adriaan; Galasso, Gennaro; Lux, Arpad; Marinucci, Lucia; Guiducci, Vincenzo; Menichelli, Maurizio; Scoccia, Alessandra; Yamac, Aylin Hatice; Mert, Kadir Ugur; Flores Rios, Xacobe; Kovarnik, Tomas; Kidawa, Michal; Moreu, Josè; Flavien, Vincent; Fabris, Enrico; Lozano Martínez-Luengas, Iñigo; Boccalatte, Marco; Bosa Ojeda, Francisco; Arellano-Serrano, Carlos; Caiazzo, Gianluca; Cirrincione, Giuseppe; Kao, Hsien Li; Sanchis Forés, Juan; Vignali, Luigi; Pereira, Helder; Manzo, Stephane; Ordoñez, Santiago; Arat Özkan, Alev; Scheller, Bruno; Lehtola, Heidi; Teles, Rui; Mantis, Christos; Antti, Ylitalo; Brum Silveira, João António; Zoni, Rodrigo; Bessonov, Ivan; Savonitto, Stefano; Kochiadakis, George; Alexopulos, Dimitrios; Uribe, Carlos E.; Kanakakis, John; Faurie, Benjamin; Gabrielli, Gabriele; Gutierrez Barrios, Alejandro; Bachini, Juan Pablo; Rocha, Alex; Tam, Frankie Chor Cheung; Rodriguez, Alfredo; Lukito, Antonia Anna; Saint-Joy, Veauthyelau; Pessah, Gustavo; Parodi, Guido; Burgadha, Mohammed Abed; Kedhi, Elvin; Lamelas, Pablo; Suryapranata, Harry; Verdoia, Monica (Lippincott Williams & Wilkins, 2025-02)
    Background: Hypertension is the most prevalent cardiovascular risk factor, with several detrimental effects on the cardiovascular system. Contrasting results have been reported so far on its prognostic role in patients ...
  • Validation of SynthSeg segmentation performance on CT using paired MRI from radiotherapy patients 
    Huisman, Selena; Maspero, Matteo; Philippens, Marielle; Verhoeff, Joost; David, Szabolcs (Academic Press Inc., 2024-12-01)
    Introduction: Manual segmentation of medical images is labor intensive and especially challenging for images with poor contrast or resolution. The presence of disease exacerbates this further, increasing the need for an ...
  • Myocardial Scarring and Sudden Cardiac Death in Young Patients with Hypertrophic Cardiomyopathy: A Multicenter Cohort Study 
    Chan, Raymond H.; Van Der Wal, Laurine; Liberato, Gabriela; Rowin, Ethan; Soslow, Jonathan; Maskatia, Shiraz; Chan, Sherwin; Shah, Amee; Fogel, Mark; Hernandez, Lazaro; Anwar, Shafkat; Voges, Inga; Carlsson, Marcus; Buddhe, Sujatha; Laser, Kai Thorsten; Greil, Gerald; Valsangiacomo-Buechel, Emanuela; Olivotto, Iacopo; Wong, Derek; Wolf, Cordula; Grotenhuis, Heynric; Rickers, Carsten; Hor, Kan; Rutz, Tobias; Kutty, Shelby; Samyn, Margaret; Johnson, Tiffanie; Hasbani, Keren; Moore, Jeremy P.; Sieverding, Ludger; Detterich, Jon; Parra, Rodrigo; Chungsomprasong, Paweena; Toro-Salazar, Olga; Roest, Arno A.W.; Dittrich, Sven; Brun, Henrik; Spinner, Joseph; Lai, Wyman; Dyer, Adrian; Jablonowsk, Robert; Meierhofer, Christian; Gabbert, Dominik; Prsa, Milan; Patel, Jyoti Kandlikar; Hornung, Andreas; Diab, Simone Goa; House, Aswathy Vaikom; Rakowski, Harry; Benson, Lee; Maron, Martin S.; Grosse-Wortmann, Lars (American Medical Association, 2024-11-13)
    Importance: The ability to predict sudden cardiac death (SCD) in children and adolescents with hypertrophic cardiomyopathy (HCM) is currently inadequate. Late gadolinium enhancement (LGE) by cardiovascular magnetic resonance ...
  • mTORC1 restricts TFE3 activity by auto-regulating its presence on lysosomes 
    Zwakenberg, Susan; Westland, Denise; van Es, Robert M.; Rehmann, Holger; Anink, Jasper; Ciapaite, Jolita; Bosma, Marjolein; Stelloo, Ellen; Liv, Nalan; Sobrevals Alcaraz, Paula; Verhoeven-Duif, Nanda M.; Jans, Judith J.M.; Vos, Harmjan R.; Aronica, Eleonora; Zwartkruis, Fried J.T. (Cell Press, 2024-11-21)
    To stimulate cell growth, the protein kinase complex mTORC1 requires intracellular amino acids for activation. Amino-acid sufficiency is relayed to mTORC1 by Rag GTPases on lysosomes, where growth factor signaling enhances ...
  • Corrigendum to “Antihypertensive medication classes and risk of incident dementia in primary care patients: a longitudinal cohort study in the Netherlands” [The Lancet Regional Health—Europe, Volume 42, July 2024, 100927] (The Lancet Regional Health - Europe (2024) 42, (S2666776224000942), (10.1016/j.lanepe.2024.100927)) 
    Schroevers, Jakob L.; Hoevenaar-Blom, Marieke P.; Busschers, Wim B.; Hollander, Monika; Van Gool, Willem A.; Richard, Edo; Van Dalen, Jan Willem; Moll van Charante, Eric P. (Elsevier, 2024-12)
    The authors have identified an error in the introduction of the main text. The correct statement should read: “Hypertension is an important risk factor for all-cause dementia, including Alzheimer's disease (AD). It affects ...
  • A yeast love triangle: multiple hybridizations shape genome evolution in the Pichia cactophila species complex 
    Mixão, V.; Saus, E.; Hagen, F.; Boekhout, T.; Stevens, R. W.; Gabaldón, T. (Zhongkai University, 2024-08-27)
    Hybrids are chimeric organisms carrying genetic material from at least two divergent parental lineages. Hybridization can contribute to the emergence of novel lineages with unique phenotypic traits that may facilitate their ...
  • Radiographic Assessment of Bone Union in Proximal Tibia and Distal Femur Osteotomies A Systematic Review 
    Bax, Eva A.; Harlianto, Netanja I.; Custers, Roel J.H.; van Egmond, Nienke; Foppen, Wouter; Kruyt, Moyo C. (Lippincott Williams & Wilkins, 2024-11-05)
    Background: Osteotomies around the knee are a well-established treatment option for early and moderate unicompartmental osteoarthritis combined with a lower extremity malalignment. Moreover, osteotomies are often combined ...
  • The Adherence Mediterranean Diet and the Quality of Sperm Parameters in Men with Infertility: A Cross-Sectional Study 
    Beigrezaei, Sara; Darabi, Zahra; Babaie, Syavash; Hosseinzadeh, Mahdieh (Shahid Sadoughi University of Medical Sciences, 2024-11-02)
    Background: It is well known that dietary factors can affect male fertility. The aim of this study was investigating the effect of Mediterranean diet on sperm quality. Methods: This cross-sectional study was conducted on ...