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UMC Repository: Recent submissions

  • Predictive models for starting antiseizure medication withdrawal following epilepsy surgery in adults 
    Ferreira-Atuesta, Carolina; de Tisi, Jane; McEvoy, Andrew W; Miserocchi, Anna; Khoury, Jean; Yardi, Ruta; Vegh, Deborah T; Butler, James; Lee, Hamin J; Deli-Peri, Victoria; Yao, Yi; Wang, Feng-Peng; Zhang, Xiao-Bin; Shakhatreh, Lubna; Siriratnam, Pakeeran; Neal, Andrew; Sen, Arjune; Tristram, Maggie; Varghese, Elizabeth; Biney, Wendy; Gray, William P; Peralta, Ana Rita; Rainha-Campos, Alexandre; Gonçalves-Ferreira, António J C; Pimentel, José; Arias, Juan Fernando; Terman, Samuel; Terziev, Robert; Lamberink, Herm J; Braun, Kees P J; Otte, Willem M; Rugg-Gunn, Fergus J; Gonzalez, Walter; Bentes, Carla; Hamandi, Khalid; O'Brien, Terence J; Perucca, Piero; Yao, Chen; Burman, Richard J; Jehi, Lara; Duncan, John S; Sander, Josemir W; Koepp, Matthias; Galovic, Marian (Oxford University Press, 2023-06-01)
    More than half of adults with epilepsy undergoing resective epilepsy surgery achieve long-term seizure freedom and might consider withdrawing antiseizure medications. We aimed to identify predictors of seizure recurrence ...
  • Unrestricted weighted least squares represent medical research better than random effects in 67,308 Cochrane meta-analyses 
    Stanley, T D; Ioannidis, John P A; Maier, Maximilian; Doucouliagos, Hristos; Otte, Willem M; Bartoš, František (Elsevier, 2023-05)
    OBJECTIVES: To evaluate how well meta-analysis mean estimators represent reported medical research and establish which meta-analysis method is better using widely accepted model selection measures: Akaike information ...
  • Transforming epilepsy research: A systematic review on natural language processing applications 
    Yew, Arister N.J.; Schraagen, Marijn; Otte, Willem M.; van Diessen, Eric (Wiley-Blackwell, 2023-02)
    Despite improved ancillary investigations in epilepsy care, patients' narratives remain indispensable for diagnosing and treatment monitoring. This wealth of information is typically stored in electronic health records and ...
  • Not surgical technique, but etiology, contralateral MRI, prior surgery, and side of surgery determine seizure outcome after pediatric hemispherotomy 
    Ramantani, Georgia; Bulteau, Christine; Cserpan, Dorottya; Otte, Willem M.; Dorfmüller, Georg; Cross, J. Helen; Zentner, Josef; Tisdall, Martin; Braun, Kees P.J. (Wiley-Blackwell, 2023-05)
    Objective: We aimed to assess determinants of seizure outcome following pediatric hemispherotomy in a contemporary cohort. Methods: We retrospectively analyzed the seizure outcomes of 457 children who underwent hemispheric ...
  • Analysis of 567,758 randomized controlled trials published over 30 years reveals trends in phrases used to discuss results that do not reach statistical significance 
    Otte, Willem M.; Vinkers, Christiaan H.; Habets, Philippe C.; van IJzendoorn, David G.P.; Tijdink, Joeri K. (Public Library of Science, 2022-02)
    The:power of language to modify the reader’s perception of :interpreting biomedical results cannot be underestimated. Misreporting and misinterpretation are pressing problems in randomized controlled trials (RCT) output. ...
  • Low Risk of Severe Complications after A Single, Post-Operative Instillation of Intravesical Chemotherapy in Patients with TaG1G2 Urothelial Bladder Carcinoma 
    the BlaZIB study group; Meijer, R.P. (IOS Press, 2021-05)
    BACKGROUND: EAU guidelines recommend a single instillation (SI) of intravesical chemotherapy (e.g. Mitomycin C) within 24 hours after transurethral resection of a bladder tumour (TURBT) in patients with low- to intermediate ...
  • Insight into bladder cancer care: study protocol of a large nationwide prospective cohort study (BlaZIB) 
    the BlaZIB study group (BioMed Central, 2020-05-20)
    Background: Despite the embedding of bladder cancer management in European guidelines, large variation in clinical practice exists for applied diagnostics and treatments. This variation may affect patients' outcomes including ...
  • The most efficient and effective BRCA1/2 testing strategy in epithelial ovarian cancer: Tumor-First or Germline-First? 
    Witjes, Vera M; Ligtenberg, Marjolijn J L; Vos, Janet R; Braspenning, Jozé C C; Ausems, Margreet G E M; Mourits, Marian J E; de Hullu, Joanne A; Adang, Eddy M M; Hoogerbrugge, Nicoline (Academic Press Inc., 2023-07)
    OBJECTIVE: Genetic testing in epithelial ovarian cancer (OC) is essential to identify a hereditary cause like a germline BRCA1/2 pathogenic variant (PV). An efficient strategy for genetic testing in OC is highly desired. ...
  • NK Cell Phenotype Is Associated With Response and Resistance to Daratumumab in Relapsed/Refractory Multiple Myeloma 
    Verkleij, Christie P M; Frerichs, Kristine A; Broekmans, Marloes E C; Duetz, Carolien; O'Neill, Chloe A; Bruins, Wassilis S C; Homan-Weert, Paola M; Minnema, Monique C; Levin, Mark-David; Broijl, Annemiek; Bos, Gerard M J; Kersten, Marie José; Klein, Saskia K; Shikhagaie, Medya M; Casneuf, Tineke; Abraham, Yann; Smets, Tina; Vanhoof, Greet; Cortes-Selva, Diana; van Steenbergen, Laure; Ramos, Elena; Verona, Raluca I; Krevvata, Maria; Sonneveld, Pieter; Zweegman, Sonja; Mutis, Tuna; van de Donk, Niels W C J (Wolters Kluwer Health, 2023-05)
    The CD38-targeting antibody daratumumab has marked activity in multiple myeloma (MM). Natural killer (NK) cells play an important role during daratumumab therapy by mediating antibody-dependent cellular cytotoxicity via ...
  • Report of consensus Panel 4 from the 11th International Workshop on Waldenstrom's macroglobulinemia on diagnostic and response criteria 
    Treon, Steven P; Tedeschi, Alessandra; San-Miguel, Jesus; Garcia-Sanz, Ramon; Anderson, Kenneth C; Kimby, Eva; Minnema, Monique C; Benevolo, Giulia; Qiu, Lugui; Yi, Shuhui; Terpos, Evangelos; Tam, Constantine S; Castillo, Jorge J; Morel, Pierre; Dimopoulos, Meletios; Owen, Roger G (W.B. Saunders, 2023-03)
    Consensus Panel 4 (CP4) of the 11th International Workshop on Waldenstrom's Macroglobulinemia (IWWM-11) was tasked with reviewing the current criteria for diagnosis and response assessment. Since the initial consensus ...
  • POU3F3-related disorder: Defining the phenotype and expanding the molecular spectrum 
    Rossi, Alessandra; Blok, Lot Snijders; Neuser, Sonja; Klöckner, Chiara; Platzer, Konrad; Faivre, Laurence Olivier; Weigand, Heike; Dentici, Maria L; Tartaglia, Marco; Niceta, Marcello; Alfieri, Paolo; Srivastava, Siddharth; Coulter, David; Smith, Lacey; Vinorum, Kristin; Cappuccio, Gerarda; Brunetti-Pierri, Nicola; Torun, Deniz; Arslan, Mutluay; Lauridsen, Mathilde F; Murch, Oliver; Irving, Rachel; Lynch, Sally A; Mehta, Sarju G; Carmichael, Jenny; Zonneveld-Huijssoon, Evelien; de Vries, Bert; Kleefstra, Tjitske; Johannesen, Katrine M; Westphall, Ian T; Hughes, Susan S; Smithson, Sarah; Evans, Julie; Dudding-Byth, Tracy; Simon, Marleen; van Binsbergen, Ellen; Herkert, Johanna C; Beunders, Gea; Oppermann, Henry; Bakal, Mert; Møller, Rikke S; Rubboli, Guido; Bayat, Allan (Wiley-Blackwell, 2023-08)
    POU3F3 variants cause developmental delay, behavioral problems, hypotonia and dysmorphic features. We investigated the phenotypic and genetic landscape, and genotype-phenotype correlations in individuals with POU3F3-related ...
  • An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients 
    Stevens Brentjens, L B P M; Obukhova, D; den Hartog, J E; Delvoux, B; Koskivuori, J; Auriola, S; Häkkinen, M R; Bui, B; van Hoogenhuijze, N E; Mackens, S; Mol, F; de Bruin, J P; Besselink, D; Teklenburg, G; Kukushkina, V; Salumets, A; Broekmans, F J M; van Golde, R J T; Zamani Esteki, M; Romano, A (Elsevier, 2023-08)
    Objective: To study the relationship between the steroid concentration in the endometrium, in serum, and the gene expression level of steroid-metabolizing enzymes in the context of endometrial receptivity in in vitro ...
  • Author Correction: Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis (Nature Communications, (2023), 14, 1, (2275), 10.1038/s41467-023-37732-1) 
    Catton, Erin A; Bonsor, Daniel A; Herrera, Carolina; Stålhammar-Carlemalm, Margaretha; Lyndin, Mykola; Turner, Claire E; Soden, Jo; van Strijp, Jos A G; Singer, Bernhard B; van Sorge, Nina M; Lindahl, Gunnar; McCarthy, Alex J (Nature Publishing Group, 2023-05-09)
    In this article the affiliation details for Bernhard B. Singer were incorrectly given as ‘Department of Medical Microbiology and Infection Prevention, Amsterdam UMC location University of Amsterdam, Amsterdam Institute for ...
  • Clinical outcomes of uninterrupted embryo culture with or without time-lapse-based embryo selection versus interrupted standard culture (SelecTIMO): a three-armed, multicentre, double-blind, randomised controlled trial 
    Kieslinger, D. C.; Vergouw, C. G.; Ramos, L.; Arends, B.; Curfs, M. H.J.M.; Slappendel, E.; Kostelijk, E. H.; Pieters, M. H.E.C.; Consten, D.; Verhoeven, M. O.; Besselink, D. E.; Broekmans, F.; Cohlen, B. J.; Smeenk, J. M.J.; Mastenbroek, S.; de Koning, C. H.; van Kasteren, Y. M.; Moll, E.; van Disseldorp, J.; Brinkhuis, E. A.; Kuijper, E. A.M.; van Baal, W. M.; van Weering, H. G.I.; van der Linden, P. J.Q.; Gerards, M. H.; Bossuyt, P. M.; van Wely, M.; Lambalk, C. B. (Elsevier, 2023-04-29)
    Background: Time-lapse monitoring is increasingly used in fertility laboratories to culture and select embryos for transfer. This method is offered to couples with the promise of improving pregnancy chances, even though ...
  • Patients as Feedback Providers: Exploring Medical Students' Credibility Judgments 
    Eijkelboom, M. C.L.; de Kleijn, R. A.M.; van Diemen, W. J.M.; Maljaars, C. D.N.; van der Schaaf, M. F.; Frenkel, J. (Ubiquity Press, 2023)
    Introduction: Patient feedback is becoming ever more important in medical education. Whether students engage with feedback is partly determined by how credible they think the feedback provider is. Despite its importance ...
  • Antibacterial and anti-inflammatory properties of host defense peptides against Staphylococcus aureus 
    Cecotto, Leonardo; van Kessel, Kok; Wolfert, Margreet A.; Vogely, Charles; van der Wal, Bart; Weinans, Harrie; van Strijp, Jos; Amin Yavari, Saber (Elsevier, 2022-10-21)
    Cationic host defense peptides (HDPs) are a promising alternative to antibiotics in the fight against Staphylococcus aureus infections. In this study, we investigated the antibacterial and immunomodulatory properties of ...
  • Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant Staphylococcus aureus to Human Group IIA-Secreted Phospholipase A2and Daptomycin 
    Kuijk, Marieke M.; Wu, Yongzheng; Van Hensbergen, Vincent P.; Shanlitourk, Gizem; Payré, Christine; Lambeau, Gérard; Man-Bovenkerk, Sandra; Herrmann, Jennifer; Müller, Rolf; Van Strijp, Jos A.G.; Pannekoek, Yvonne; Touqui, Lhousseine; Van Sorge, Nina M. (S. Karger AG, 2023)
    Methicillin-resistant Staphylococcus aureus (MRSA) has been classified as a high priority pathogen by the World Health Organization underlining the high demand for new therapeutics to treat infections. Human group IIA-secreted ...
  • Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis 
    Catton, Erin A.; Bonsor, Daniel A.; Herrera, Carolina; Stålhammar-Carlemalm, Margaretha; Lyndin, Mykola; Turner, Claire E.; Soden, Jo; van Strijp, Jos A.G.; Singer, Bernhard B.; van Sorge, Nina M.; Lindahl, Gunnar; McCarthy, Alex J. (Nature Publishing Group, 2023-04-20)
    Life-threatening bacterial infections in women after childbirth, known as puerperal sepsis, resulted in classical epidemics and remain a global health problem. While outbreaks of puerperal sepsis have been ascribed to ...
  • MABTRAINS: Numerous anti-infective modalities ride together 
    van Strijp, Jos A.G. (Cell Press, 2023-05-10)
    In this issue of Cell Host & Microbe, Buckley et al. report a biological entity called a mAbtyrin, which combines various antimicrobial functions. The authors demonstrate through in vitro and in vivo experiments that this ...
  • Impact of network treatment in patients with resected pancreatic cancer on use and timing of chemotherapy and survival 
    Hopstaken, Jana S; Vissers, Pauline A J; Quispel, Rutger; de Vos-Geelen, Judith; Brosens, Lodewijk A A; de Hingh, Ignace H J T; van der Geest, Lydia G; Besselink, Marc G; van Laarhoven, Kees J H M; Stommel, Martijn W J (John Wiley & Sons Inc., 2023-06-01)
    Background: Centralization of pancreatic cancer surgery aims to improve postoperative outcomes. Consequently, patients with pancreatic cancer may undergo pancreatic surgery in an expert centre and adjuvant chemotherapy in ...