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Structural changes after ankle joint distraction in haemophilic arthropathy: an explorative study investigating biochemical markers and 3D joint space width

van Bergen, Eline D P; Mastbergen, Simon C; Lafeber, Floris P J G; Bay-Jensen, Anne-Christine; Madsen, Sofie F; Port, Helena; Foppen, Wouter; Schutgens, Roger E G; Jansen, Mylène P; van Vulpen, Lize F D (Wiley-Blackwell, 2023-05)

INTRODUCTION: Ankle joint distraction (AJD) is a promising treatment for patients with severe haemophilic ankle arthropathy (HAA). However, some patients showed no clinical improvement after AJD and these differences may ...
VACCELERATE Site Network: Real-time definition of clinical study capacity in Europe

VACCELERATE Consortium. Electronic address: trialsites@vaccelerate.eu (Elsevier, 2023-06-13)

BACKGROUND: The inconsistent European vaccine trial landscape rendered the continent of limited interest for vaccine developers. The VACCELERATE consortium created a network of capable clinical trial sites throughout Europe. ...
Incidence and outcomes of uterine rupture in women with unscarred, preterm or prelabour uteri: data from the international network of obstetric survey systems

INOSS (the International Network of Obstetrics Survey Systems) (Wiley-Blackwell, 2023-11)

Objective: Analysis of atypical cases of uterine rupture, namely, uterine rupture occurring in unscarred, preterm or prelabour uteri. Design: Descriptive multi-country population-based study. Setting: Ten high-income ...
Randomized controlled study of pain education in patients receiving radiotherapy for painful bone metastases

Geerling, Jenske I; van der Linden, Yvette M; Raijmakers, Natasja J H; Vermeulen, Karin M; de Nijs, Ellen J M; Westhoff, Paulien G; de Bock, Geertruida H; de Graeff, Alexander; Reyners, Anna K L (Elsevier Ireland Ltd, 2023-08)

Background: Although short-course radiotherapy is an effective treatment for patients with painful bone metastases, pain is not always sufficiently controlled. We therefore investigated the additional effect of a nurse-led ...
Diagnostic Utility of Menin Immunohistochemistry in Patients With Multiple Endocrine Neoplasia Type 1 Syndrome

Verschuur, Anna Vera D; Kok, Aranxa S M; Morsink, Folkert H M; de Leng, Wendy W J; van den Broek, Medard F M; Koudijs, Marco J; Offerhaus, Johan A; Valk, Gerlof D; Vriens, Menno R; van Nesselrooij, Bernadette P M; Hackeng, Wenzel M; Brosens, Lodewijk A A (Lippincott Williams & Wilkins, 2023-07-01)

A clinical diagnosis of multiple endocrine neoplasia type 1 (MEN1) syndrome is usually confirmed with genetic testing in the germline. It is expected that menin protein expression is lost in MEN1-related tumors. Therefore, ...
ASO Visual Abstract: Nationwide Impact of Centralization, Neoadjuvant Therapy, Minimally Invasive Surgery, and Standardized Pathology Reporting on R0 Resection and Overall Survival in Pancreatoduodenectomy for Pancreatic Cancer

Dutch Pancreatic Cancer Group (Springer New York, 2023-08)
Nationwide Impact of Centralization, Neoadjuvant Therapy, Minimally Invasive Surgery, and Standardized Pathology Reporting on R0 Resection and Overall Survival in Pancreatoduodenectomy for Pancreatic Cancer

Dutch Pancreatic Cancer Group (Springer New York, 2023-08)

Background: Surgeons aim for R0 resection in patients with pancreatic cancer to improve overall survival. However, it is unclear whether recent changes in pancreatic cancer care such as centralization, increased use of ...
Multimodal nocturnal seizure detection in children with epilepsy: a prospective, multicenter, long-term, in-home trial

Dutch TeleEpilepsy Consortium (Wiley-Blackwell, 2023-08)

OBJECTIVE: There is a pressing need for reliable automated seizure detection in epilepsy care. Performance evidence on ambulatory non-electroencephalography-based seizure detection devices is low, and evidence on their ...
The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study

EU-GEI WP2 Group (Cambridge University Press, 2023-11-02)

Background While cannabis use is a well-established risk factor for psychosis, little is known about any association between reasons for first using cannabis (RFUC) and later patterns of use and risk of psychosis. Methods ...
Tobacco use in first-episode psychosis, a multinational EU-GEI study

EU-GEI WP2 Group (Cambridge University Press, 2023-11)

BACKGROUND: Tobacco is a highly prevalent substance of abuse in patients with psychosis. Previous studies have reported an association between tobacco use and schizophrenia. The aim of this study was to analyze the ...
Outcomes of hyperbolic tapering of antidepressants

van Os, Jim; Groot, Peter C (SAGE Publications Inc., 2023-01-01)

BACKGROUND: In patients attempting to discontinue their antidepressant medication, there have been no prospective studies on patterns of withdrawal as a function of the rate of antidepressant reduction during the tapering ...
Adjusting for population stratification in polygenic risk score analyses: a guide for model specifications in the UK Biobank

Lin, Bochao Danae; Pries, Lotta-Katrin; van Os, Jim; Luykx, Jurjen J; Rutten, Bart P F; Guloksuz, Sinan (Springer Nature, 2023-09)

The current study was conducted to provide a general guidance for model specifications in polygenic risk score (PRS) analyses of the UK Biobank, such as adjusting for covariates (i.e. age, sex, recruitment centers, and ...
The Laban/Bartenieff Movement System in gait-analysis reveals upper-lower body movement dysconnectivity in psychotic disorders

van de Meent, Ilona; Maat, Arija; Boute, Mikel; van Dellen, Edwin; Cahn, Wiepke (Elsevier, 2023-06)
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium; Stanley Global Asia Initiatives; Psychosis Endophenotypes International Consortium; Wellcome Trust Case Control Consortium (Elsevier, 2023-05-19)

Genetics have nominated many schizophrenia risk genes and identified convergent signals between schizophrenia and neurodevelopmental disorders. However, functional interpretation of the nominated genes in the relevant brain ...
Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium

Dwyer, Dominic B; Chand, Ganesh B; Pigoni, Alessandro; Khuntia, Adyasha; Wen, Junhao; Antoniades, Mathilde; Hwang, Gyujoon; Erus, Guray; Doshi, Jimit; Srinivasan, Dhivya; Varol, Erdem; Kahn, Rene S; Schnack, Hugo G; Meisenzahl, Eva; Wood, Stephen J; Zhuo, Chuanjun; Sotiras, Aristeidis; Shinohara, Russell T; Shou, Haochang; Fan, Yong; Schaulfelberger, Maristela; Rosa, Pedro; Lalousis, Paris A; Upthegrove, Rachel; Kaczkurkin, Antonia N; Moore, Tyler M; Nelson, Barnaby; Gur, Raquel E; Gur, Ruben C; Ritchie, Marylyn D; Satterthwaite, Theodore D; Murray, Robin M; Di Forti, Marta; Ciufolini, Simone; Zanetti, Marcus V; Wolf, Daniel H; Pantelis, Christos; Crespo-Facorro, Benedicto; Busatto, Geraldo F; Davatzikos, Christos; Koutsouleris, Nikolaos; Dazzan, Paola (Springer Nature, 2023-05)

Using machine learning, we recently decomposed the neuroanatomical heterogeneity of established schizophrenia to discover two volumetric subgroups-a 'lower brain volume' subgroup (SG1) and an 'higher striatal volume' ...
Gene expression profiling of monocytes in recent-onset schizophrenia

Kübler, Raphael; Ormel, Paul R; Sommer, Iris E C; Kahn, René S; de Witte, Lot D (Academic Press Inc., 2023-07)

Immune-related mechanisms have been suggested to be involved in schizophrenia. Various studies have shown changes in monocytes isolated from the blood of schizophrenia patients, including changes in monocyte numbers, as ...
Coping with Administrative Workload: a Pilot Study in the Usefulness of a Workshop for Psychiatric Trainees

Deschamps, Peter; Seker, Asilay; van der Schaaf, Marieke; Piot, Marie Aude (Springer International Publishing AG, 2023-10)

Objective: Administrative workload may have detrimental effects on medical postgraduate trainee satisfaction, capacity, and quality of care. Best-practice guidelines to help trainees cope have yet to be developed. This ...
Meningococcal ACWY conjugate vaccine immunogenicity and safety in adolescents with juvenile idiopathic arthritis and inflammatory bowel disease: A prospective observational cohort study

Ohm, Milou; van Straalen, Joeri W; Zijlstra, Marieke; de Joode-Smink, Gerrie; Jasmijn Sellies, Anne; Swart, Joost F; Vastert, Sebastiaan J; van Montfrans, Joris M; Bartels, Marije; van Royen-Kerkhof, Annet; Wildenbeest, Joanne G; Lindemans, Caroline A; Wolters, Victorien; Wennink, Roos A W; de Boer, Joke H; Knol, Mirjam J; Heijstek, Marloes W; Sanders, Elisabeth A M; Verduyn-Lunel, Frans M; Berbers, Guy A M; Wulffraat, Nico M; Jansen, Marc H A (Elsevier, 2023-06-07)

Background: Immunogenicity to meningococcal serogroup ACWY (MenACWY) conjugate vaccine has not been studied in immunocompromised minors with juvenile idiopathic arthritis (JIA) or inflammatory bowel disease (IBD). We ...
What matters most to pediatric rheumatologists in deciding whether to discontinue biologics in a child with juvenile idiopathic arthritis?: A best-worst scaling survey

Currie, Gillian R; Groothuis-Oudshoorn, Catherina G M; Twilt, Marinka; Kip, Michelle M A; IJzerman, Maarten J; Benseler, Susanne M; Swart, Joost F; Vastert, Sebastiaan J; Wulffraat, Nico M; Yeung, Rae; Marshall, Deborah A (Springer Science and Business Media Deutschland GmbH, 2023-08)

OBJECTIVES: Care for JIA patients has been transformed in the biologics era; however, biologics carry important (although rare) risks and are costly. Flares after biological withdrawal are seen frequently, yet there is ...
Standardization and quality control of Doppler and fetal biometric ultrasound measurements in low-income setting

Ali, S; Byamugisha, J; Kawooya, M G; Kakibogo, I M; Ainembabazi, I; Biira, E A; Kagimu, A N; Migisa, A; Munyakazi, M; Kuniha, S; Scheele, C; Papageorghiou, A T; Klipstein-Grobusch, K; Rijken, M J (John Wiley & Sons Inc., 2023-04)

OBJECTIVE: The aim of this study was to determine the quality of fetal biometry and pulsed-wave Doppler ultrasound measurements in a prospective cohort study in Uganda. METHODS: This was an ancillary study of the Ending ...

Now showing items 9921-9940 of 40729