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The arrhythmogenic cardiomyopathy phenotype associated with PKP2 c.1211dup variant

European Reference Network for rare, low prevalence and complex diseases of the heart: ERN GUARD-Heart (Bohn Stafleu van Loghum, 2023-08)

Background: The arrhythmogenic cardiomyopathy (ACM) phenotype, with life-threatening ventricular arrhythmias and heart failure, varies according to genetic aetiology. We aimed to characterise the phenotype associated with ...
Zanubrutinib Versus Ibrutinib in Symptomatic Waldenström Macroglobulinemia: Final Analysis From the Randomized Phase III ASPEN Study

Dimopoulos, Meletios A; Opat, Stephen; D'Sa, Shirley; Jurczak, Wojciech; Lee, Hui-Peng; Cull, Gavin; Owen, Roger G; Marlton, Paula; Wahlin, Björn E; Garcia-Sanz, Ramon; McCarthy, Helen; Mulligan, Stephen; Tedeschi, Alessandra; Castillo, Jorge J; Czyz, Jaroslaw; Fernández de Larrea, Carlos; Belada, David; Libby, Edward; Matous, Jeffrey; Motta, Marina; Siddiqi, Tanya; Tani, Monica; Trněný, Marek; Minnema, Monique C; Buske, Christian; Leblond, Veronique; Treon, Steven P; Trotman, Judith; Chan, Wai Y; Schneider, Jingjing; Allewelt, Heather; Patel, Sheel; Cohen, Aileen; Tam, Constantine S (Lippincott Williams & Wilkins, 2023-11-20)

The phase III ASPEN study demonstrated the comparable efficacy and improved safety of zanubrutinib versus ibrutinib in patients with Waldenström macroglobulinemia (WM). Here, we report long-term follow-up outcomes from ...
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU

Dutch COVID-19 ICU Research Consortium (Elsevier Limited, 2023-09)

BACKGROUND: - Subgroup discovery (SGD) is the automated splitting of the data into complex subgroups. Various SGD methods have been applied to the medical domain, but none have been extensively evaluated. We assess the ...
ESCMID/EUCIC clinical practice guidelines on perioperative antibiotic prophylaxis in patients colonized by multidrug-resistant Gram-negative bacteria before surgery

Righi, Elda; Mutters, Nico T.; Guirao, Xavier; del Toro, Maria Dolores; Eckmann, Christian; Friedrich, Alex W.; Giannella, Maddalena; Kluytmans, Jan; Presterl, Elisabeth; Christaki, Eirini; Cross, Elizabeth L.A.; Visentin, Alessandro; Sganga, Gabriele; Tsioutis, Constantinos; Tacconelli, Evelina (Elsevier, 2023-04)

Scope: The aim of the guidelines is to provide recommendations on perioperative antibiotic prophylaxis (PAP) in adult inpatients who are carriers of multidrug-resistant Gram-negative bacteria (MDR-GNB) before surgery. ...
Long-term immunoprotection after live attenuated measles-mumps-rubella booster vaccination in children with juvenile idiopathic arthritis

Hamad Saied, Mohamad; van Straalen, Joeri W; de Roock, Sytze; de Joode-Smink, Gerrie C J; Verduyn Lunel, Frans M; Swart, Joost F; Wulffraat, Nico M; Jansen, Marc H A (Elsevier, 2023-08-23)

INTRODUCTION: Vaccines, especially live attenuated vaccines, in children with JIA pose a great challenge due to both potential lower immunogenicity and safety as a result of immunosuppressive treatment. For many years, in ...
Immune Responses 6 Months After mRNA-1273 COVID-19 Vaccination and the Effect of a Third Vaccination in Patients with Inborn Errors of Immunity

VACOPID Research Group (Springer New York, 2023-08)

Purpose: Patients with inborn errors of immunity (IEI) are at increased risk of severe coronavirus disease-2019 (COVID-19). Effective long-term protection against COVID-19 is therefore of great importance in these patients, ...
MYH7 p.(Arg1712Gln) is pathogenic founder variant causing hypertrophic cardiomyopathy with overall relatively delayed onset

European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (Bohn Stafleu van Loghum, 2023-08)

INTRODUCTION: The MYH7 c.5135G > A p.(Arg1712Gln) variant has been identified in several patients worldwide and is classified as pathogenic in the ClinVar database. We aimed to delineate its associated phenotype and evaluate ...
Identification of circulating monocytes as producers of tuberculosis disease biomarker C1q

Niewold, Paula; Dijkstra, Douwe J; Cai, Yi; Goletti, Delia; Palmieri, Fabrizio; van Meijgaarden, Krista E; Verreck, Frank A W; Akkerman, Onno W; Hofland, Regina W; Delemarre, Eveline M; Nierkens, Stefan; Verheul, Marije K; Pollard, Andrew J; van Dissel, Jaap T; Ottenhoff, Tom H M; Trouw, Leendert A; Joosten, Simone A (Nature Publishing Group, 2023-07-18)

Tuberculosis (TB) is a prevalent disease causing an estimated 1.6 million deaths and 10.6 million new cases annually. Discriminating TB disease from differential diagnoses can be complex, particularly in the field. Increased ...
Association between diabetes overtreatment in older multimorbid patients and clinical outcomes: an ancillary European multicentre study

Christiaens, Antoine; Baretella, Oliver; Del Giovane, Cinzia; Rodondi, Nicolas; Knol, Wilma; Peters, Mike; Jennings, Emma; O'Mahony, Denis; Spinewine, Anne; Boland, Benoit; Henrard, Séverine (Oxford University Press, 2023-01-01)

Background: Diabetes overtreatment is a frequent and severe issue in multimorbid older patients with type 2 diabetes (T2D). Objective: This study aimed at assessing the association between diabetes overtreatment and 1-year ...
Psychosocial functioning of adult siblings of Dutch very long-term survivors of childhood cancer: DCCSS-LATER 2 psycho-oncology study

Dutch LATER Study group (John Wiley & Sons Inc., 2023-09)

OBJECTIVE: To describe psychosocial outcomes among adult siblings of very long-term childhood cancer survivors (CCS), to compare these outcomes to reference populations and to identify factors associated with siblings' ...
Radical skeletal metastatic site irradiation in highrisk neuroblastoma: systematic review and proposal for a randomised trial: a report from the SIOPEN Radiotherapy Committee

Keshwani, Karimali; Boterberg, Tom; Dieckmann, Karin; Janssens, Geert O.; Laprie, Anne; Timmermann, Beate; Gaze, Mark N. (OAE Publishing Inc., 2023-02-14)

Aim: Neuroblastoma has a variable outcome depending on age, stage, and molecular pathology. Distant metastatic disease is the central feature of high-risk disease. Recommendations for irradiating persistent metastatic ...
The healthy beverage index is not associated with insulin resistance, prediabetes and type 2 diabetes risk in the Rotterdam Study

Jacobo Cejudo, Maria G; Ochoa-Rosales, Carolina; Ahmadizar, Fariba; Kavousi, Maryam; Geleijnse, Johanna M; Voortman, Trudy (Springer Science and Business Media Deutschland GmbH, 2023-10)

PURPOSE: Whether beverage quality affects changes in glycaemic traits and type 2 diabetes (T2D) risk is unknown. We examined associations of a previously developed Healthy Beverage Index (HBI) with insulin resistance, and ...
Glial cell response and microthrombosis in aneurysmal subarachnoid hemorrhage patients: An autopsy study

Koopman, Inez; Van Dijk, Bart J.; Zuithoff, Nicolaas P.A.; Sluijs, Jacqueline A.; Van Der Kamp, Marije J.; Baldew, Zelonna A.V.; Frijns, Catharina J.M.; Rinkel, Gabriel J.E.; Hol, Elly M.; Vergouwen, Mervyn D.I. (Lippincott Williams & Wilkins, 2023-08-21)

Neuroinflammation and microthrombosis may be underlying mechanisms of brain injury after aneurysmal subarachnoid hemorrhage (aSAH), but they have not been studied in relation to each other. In postmortem brain tissue, we ...
'It's communication between people who are going through the same thing': experiences of informal interactions in hospital cancer treatment settings

P Grant, Matthew; A M Philip, Jennifer; Deliens, Luc; Komesaroff, Paul A (Springer-Verlag, 2023-07-03)

PURPOSE: In hospital settings, patients, visitors, and staff engage in many interactions outside formal clinical encounters. Whilst many of these may be inconsequential, others contribute significantly to how patients and ...
Systematic Review of Active Surveillance for Clinically Localised Prostate Cancer to Develop Recommendations Regarding Inclusion of Intermediate-risk Disease, Biopsy Characteristics at Inclusion and Monitoring, and Surveillance Repeat Biopsy Strategy

Willemse, Peter Paul M.; Davis, Niall F.; Grivas, Nikolaos; Zattoni, Fabio; Lardas, Michael; Briers, Erik; Cumberbatch, Marcus G.; De Santis, Maria; Dell'Oglio, Paolo; Donaldson, James F.; Fossati, Nicola; Gandaglia, Giorgio; Gillessen, Silke; Grummet, Jeremy P.; Henry, Ann M.; Liew, Matthew; MacLennan, Steven; Mason, Malcolm D.; Moris, Lisa; Plass, Karin; O'Hanlon, Shane; Omar, Muhammad Imran; Oprea-Lager, Daniela E.; Pang, Karl H.; Paterson, Catherine C.; Ploussard, Guillaume; Rouvière, Olivier; Schoots, Ivo G.; Tilki, Derya; van den Bergh, Roderick C.N.; Van den Broeck, Thomas; van der Kwast, Theodorus H.; van der Poel, Henk G.; Wiegel, Thomas; Yuan, Cathy Yuhong; Cornford, Philip; Mottet, Nicolas; Lam, Thomas B.L. (Elsevier, 2022-04)

Context: There is uncertainty regarding the most appropriate criteria for recruitment, monitoring, and reclassification in active surveillance (AS) protocols for localised prostate cancer (PCa). Objective: To perform a ...
The short and long-term effects of a lifestyle intervention in children with mental illnesses: a randomized controlled trial (Movementss study)

van Tetering, Emilie M A; Muskens, Jet B; Deenik, Jeroen; Pillen, Sigrid; Cahn, Wiepke; von Rosenstiel, Inès; Oomen, Mieke; Rommelse, Nanda N; Staal, Wouter G; Klip, Helen (BioMed Central, 2023-07-21)

BACKGROUND: A lifestyle including poor diet, physical inactivity, excessive gaming and inadequate sleep hygiene is frequently seen among Dutch children. These lifestyle behaviors can cause long-term health problems later ...
Differences in Patterns of Stimulant Use and Their Impact on First-Episode Psychosis Incidence: An Analysis of the EUGEI Study

EU-GEI WP2 Group (Oxford University Press, 2023-09-07)

Background: Use of illegal stimulants is associated with an increased risk of psychotic disorder. However, the impact of stimulant use on odds of first-episode psychosis (FEP) remains unclear. Here, we aimed to describe ...
The within-person bidirectional association between physical activity and loneliness in the daily lives of adolescents and young adults

Jennen, Lise; Mazereel, Victor; Vansteelandt, Kristof; Menne-Lothmann, Claudia; Decoster, Jeroen; Derom, Catherine; Thiery, Evert; Rutten, Bart P.F.; Jacobs, Nele; van Os, Jim; Wichers, Marieke; De Hert, Marc; Vancampfort, Davy; van Winkel, Ruud (Elsevier, 2023-03)

Adolescents and young adults are at high risk for experiencing loneliness, a well-established risk factor for mental health symptoms. Being physically active is known to reduce feelings of loneliness. We explored the ...
Coping and sleep quality in youth: An Experience Sampling study

Hagemann, Noëmi; Kirtley, Olivia J.; Lafit, Ginette; Vancampfort, Davy; Wampers, Martien; Decoster, Jeroen; Derom, Catherine; Gülöksüz, Sinan; De Hert, Marc; Jacobs, Nele; Menne-Lothmann, Claudia; Rutten, Bart P.F.; Thiery, Evert; van Os, Jim; van Winkel, Ruud; Wichers, Marieke; Myin-Germeys, Inez (John Wiley & Sons Inc., 2023-04)

Introduction: Sleep quality is closely linked with mental health. Two factors that influence sleep are coping style and locus of control, yet these have not been investigated in daily life. In this study, we examined ...
Speech Illusions in People at Clinical High Risk for Psychosis Linked to Clinical Outcome

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands (GJB, GJER) (Oxford University Press, 2023-03-01)

Background and hypothesis: Around 20% of people at clinical high risk (CHR) for psychosis later develop a psychotic disorder, but it is difficult to predict who this will be. We assessed the incidence of hearing speech ...

Now showing items 9501-9520 of 40729