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Career development of doctorally prepared nurses

van Dongen, Lisa; Hafsteinsdottir, Thóra B.; Broome, Marion E.; Suhonen, Riitta; Leino-Kilpi, Helena (Wiley-Blackwell, 2024-03)

Aim: To integrate research literature regarding careers, career development and factors influencing the career development of doctorally prepared nurses. Design: An integrative review. Data Sources: Medline, CINAHL and ...
The efficacy and tolerability of latency-reversing agents in reactivating the HIV-1 reservoir in clinical studies: a systematic review

Debrabander, Quinten; Hensley, Kathryn S.; Psomas, Christina K.; Bramer, Wichor; Mahmoudi, Tokameh; van Welzen, Berend J.; Verbon, Annelies; Rokx, Casper (Elsevier, 2023-09)

Introduction: Understanding the clinical potency of latency-reversing agents (LRAs) on the HIV-1 reservoir is useful to deploy future strategies. This systematic review evaluated the effects of LRAs in human intervention ...
Global prevalence, cascade of care, and prophylaxis coverage of hepatitis B in 2022: a modelling study

The Polaris Observatory Collaborators (Elsevier Limited, 2023-10)

Background: The 2016 World Health Assembly endorsed the elimination of hepatitis B virus (HBV) infection as a public health threat by 2030; existing therapies and prophylaxis measures make such elimination feasible, even ...
Analysis of complications and revisions after spine surgery in 270 multiple myeloma patients with spinal involvement

Zijlstra, H; Pierik, R J; Crawford, A M; Tobert, D G; Wolterbeek, N; Oosterhoff, J H F; Delawi, D; Terpstra, W E; Kempen, D H R; Verlaan, J J; Schwab, J H (Springer-Verlag, 2023-12)

BACKGROUND CONTEXT: Patients with multiple myeloma (MM) are at increased risk of infections and suffer from poor bone quality due to their disseminated malignant bone disease. Therefore, postoperative complications may ...
The prevalence of vascular and metabolic complications after lung transplant in people with cystic fibrosis in a Dutch cohort

Oppelaar, Lisa M; Luijk, Bart; Heijerman, Harry G M; De Valk, Harold W; van Meerkerk, Gerdien Belle- (Universidade de Sao Paulo. Museu de Zoologia, 2023)

BACKGROUND: With improvements in care for people with Cystic Fibrosis (pwCF), total survival after Lung Transplantation (LTx) will be longer. Therefore, this population's up-to-date analysis of late-onset post-transplant ...
Between theory and practice: educators’ perceptions on assessment quality criteria and its impact on student learning

Schellekens, Lonneke H.; Kremer, Wim D.J.; Van der Schaaf, Marieke F.; Van der Vleuten, Cees P.M.; Bok, Harold G.J. (Frontiers Media S. A., 2023-06)

Introduction: The shift toward an assessment for learning culture includes assessment quality criteria that emphasise the learning process, such as transparency and learning impact, in addition to the traditional validity ...
Continuous infusion of cefiderocol in a critically ill patient with continuous venovenous haemofiltration

Möhlmann, Julia E.; van Luin, Matthijs; Uijtendaal, Esther V.; Zahr, Noël; Sikma, Maaike A. (Wiley-Blackwell, 2023-12)

Cefiderocol is a broad-spectrum cephalosporin antibiotic and is indicated in patients with difficult-to-treat Gram-negative bacterial infections. Cefiderocol is applied as a 2–4-times daily prolonged 3-h infusion. The ...
ASO Visual Abstract: Survival of Patients with Deficient Mismatch Repair Versus Proficient Mismatch Repair Metastatic Colorectal Cancer Receiving Curative-Intent Local Treatment of Metastases in a Nationwide Cohort

Zwart, Koen; van der Baan, Frederieke H; Punt, Cornelis J A; Wensink, G Emerens; Bolhuis, Karen; Laclé, Miangela M; van Grevenstein, Wilhelmina M U; Hagendoorn, Jeroen; de Hingh, Ignace H; Koopman, Miriam; Vink, Geraldine; Roodhart, Jeanine (Springer New York, 2023-10)
Perioperative Systemic Therapy Versus Cytoreductive Surgery and HIPEC Alone for Resectable Colorectal Peritoneal Metastases: Patient-Reported Outcomes of a Randomized Phase II Trial

the Dutch Peritoneal Oncology Group and the Dutch Colorectal Cancer Group (Springer New York, 2023-05)

Background: As part of a randomized phase II trial in patients with isolated resectable colorectal peritoneal metastases (CPMs), the present study compared patient-reported outcomes (PROs) of patients treated with perioperative ...
Evaluation of Intratumoral Response Heterogeneity in Metastatic Colorectal Cancer and Its Impact on Patient Overall Survival: Findings from 10,551 Patients in the ARCAD Database

Ou, Fang Shu; Ahn, Daniel H.; Dixon, Jesse G.; Grothey, Axel; Lou, Yiyue; Kasi, Pashtoon M.; Hubbard, Joleen M.; Van Cutsem, Eric; Saltz, Leonard B.; Schmoll, Hans Joachim; Goldberg, Richard M.; Venook, Alan P.; Hoff, Paulo; Douillard, Jean Yves; Hecht, J. Randolph; Hurwitz, Herbert; Punt, Cornelis J.A.; Koopman, Miriam; Bokemeyer, Carsten; Fuchs, Charles S.; Diaz-Rubio, Eduardo; Tebbutt, Niall C.; Cremolini, Chiara; Kabbinavar, Fairooz F.; Bekaii-Saab, Tanios; Chibaudel, Benoist; Yoshino, Takayuki; Zalcberg, John; Adams, Richard A.; de Gramont, Aimery; Shi, Qian (Multidisciplinary Digital Publishing Institute (MDPI), 2023-08)

Metastatic colorectal cancer (mCRC) is a heterogeneous disease that can evoke discordant responses to therapy among different lesions in individual patients. The Response Evaluation Criteria in Solid Tumors (RECIST) criteria ...
Will standardization kill innovation?

Wijnen, Jannie P.; Seiberlich, Nicole; Golay, Xavier (Springer-Verlag, 2023-08)
Optimization of performance of Dutch newborn screening for cystic fibrosis

Bouva, M J; Dankert-Roelse, J E; van der Ploeg, Cpb; Verschoof-Puite, R K; Zomer-van Ommen, D D; Gille, Jjp; Jakobs, B S; Heijnen, Mla; de Winter-de Groot, K M (Elsevier, 2024-01)

BACKGROUND: Dutch newborn screening (NBS) for Cystic Fibrosis (CF) introduced in 2011 showed a sensitivity of 90% and a positive predictive value (PPV) of 63%. We describe a study including an optimization phase and ...
Desmopressin in nonsevere hemophilia A: patient perspectives on use and efficacy

Romano, Lorenzo G R; van Vulpen, Lize F D; den Exter, Paul L; Heubel-Moenen, Floor C J I; Hooijmeijer, Helene L; Coppens, Michiel; Fijnvandraat, Karin; Schols, Saskia E M; Ypma, Paula F; Smit, Cees; Driessens, Mariëtte H E; Rosendaal, Frits R; van der Bom, Johanna G; Gouw, Samantha C; Kruip, Marieke J H A (Elsevier, 2023-07)

Background: Desmopressin increases plasma factor VIII and von Willebrand factor levels in persons with nonsevere hemophilia A. Patients’ perspectives on desmopressin are relevant to increase and optimize its suboptimal ...
Pre-operative synovial hyperaemia in haemophilia patients undergoing total knee replacement and the effects of genicular artery embolization: A retrospective cohort study

Foppen, Wouter; van der Schaaf, Irene C; van Leeuwen, Flora H P; Verlind, David H; van Vulpen, Lize F D; Vogely, H Charles; Barentsz, Maarten W (Wiley-Blackwell, 2023-09)

AIM: Haemophilia is characterized by recurrent joint bleeding caused by a lack of clotting factor VIII or IX. Due to repeated joint bleeding, end-stage arthropathy occurs in relatively young patients. A total knee replacement ...
Transition readiness among adolescents and young adults with haemophilia in the Netherlands: Nationwide questionnaire study

Brands, Martijn R; Janssen, Ebony A M; Cnossen, Marjon H; Smit, Cees; van Vulpen, Lize F D; van der Valk, Paul R; Eikenboom, Jeroen; Heubel-Moenen, Floor C J I; Hooimeijer, Louise; Ypma, Paula; Nieuwenhuizen, Laurens; Coppens, Michiel; Schols, Saskia E M; Laros-van Gorkom, Britta A P; Leebeek, Frank W G; Driessens, Mariëtte H E; Rosendaal, Frits R; van der Bom, Johanna G; Fijnvandraat, Karin; Gouw, Samantha C (Wiley-Blackwell, 2023-09)

INTRODUCTION: Care for adolescents with haemophilia is transferred from paediatric to adult care around the age of 18 years. Transition programs help to prepare adolescents for this transfer and prevent declining treatment ...
Deep neural networks reveal novel sex-specific electrocardiographic features relevant for mortality risk

Siegersma, Klaske R.; Van De Leur, Rutger R.; Onland-Moret, N. Charlotte; Leon, David A.; Diez-Benavente, Ernest; Rozendaal, Liesbeth; Bots, Michiel L.; Coronel, Ruben; Appelman, Yolande; Hofstra, Leonard; Van Der Harst, Pim; Doevendans, Pieter A.; Hassink, Rutger J.; Den Ruijter, Hester M.; Van Es, Rene (Oxford University Press, 2022-06)

Aims: Incorporation of sex in study design can lead to discoveries in medical research. Deep neural networks (DNNs) accurately predict sex based on the electrocardiogram (ECG) and we hypothesized that misclassification of ...
Machine-learning-derived heart and brain age are independently associated with cognition

Iakunchykova, Olena; Schirmer, Henrik; Vangberg, Torgil; Wang, Yunpeng; Benavente, Ernest D.; van Es, René; van de Leur, Rutger R.; Lindekleiv, Haakon; Attia, Zachi I.; Lopez-Jimenez, Francisco; Leon, David A.; Wilsgaard, Tom (Wiley-Blackwell, 2023-09)

Background and purpose: A heart age biomarker has been developed using deep neural networks applied to electrocardiograms. Whether this biomarker is associated with cognitive function was investigated. Methods: Using 12-lead ...
Variational auto-encoders improve explainability over currently employed heatmap methods for deep learning-based interpretation of the electrocardiogram

Van De Leur, Rutger R.; Hassink, Rutger J.; Van Es, Rene (Oxford University Press, 2022-12)
Electrocardiogram Devices for Home Use: Technological and Clinical Scoping Review

Zepeda-Echavarria, Alejandra; de van Leur, Rutger R.van; van Sleuwen, Meike; Hassink, Rutger J.; Wildbergh, Thierry X.; Doevendans, Pieter A.; Jaspers, Joris; van Es, René (JMIR Publications Inc., 2023)

Background: Electrocardiograms (ECGs) are used by physicians to record, monitor, and diagnose the electrical activity of the heart. Recent technological advances have allowed ECG devices to move out of the clinic and into ...
Deep neural network-based clustering of deformation curves reveals novel disease features in PLN pathogenic variant carriers

Taha, Karim; van de Leur, Rutger R.; Vessies, Melle; Mast, Thomas P.; Cramer, Maarten J.; Cauwenberghs, Nicholas; Verstraelen, Tom E.; de Brouwer, Remco; Doevendans, Pieter A.; Wilde, Arthur; Asselbergs, Folkert W.; van den Berg, Maarten P.; D’hooge, Jan; Kuznetsova, Tatiana; Teske, Arco J.; van Es, René (Springer Netherlands, 2023-11)

Echocardiographic deformation curves provide detailed information on myocardial function. Deep neural networks (DNNs) may enable automated detection of disease features in deformation curves, and improve the clinical ...

Now showing items 9081-9100 of 40729