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Now showing items 8941-8960 of 40729

Perspective-Taking and Perspective-Sharing in Pediatric Education: Exploring Connections Between Strategies of Medical Students and Patients' Caregivers

Eijkelboom, M C L; de Kleijn, R A M; Baten, L; Frenkel, J; van der Schaaf, M F (Ubiquity Press, 2023-10-01)

INTRODUCTION: In pediatric education, caregivers are increasingly involved to share their perspective. Yet, an in-depth understanding of the perspective-taking process between medical students and caregivers is lacking. ...
Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe

PERFORM Consortium (Oxford University Press, 2024-03-15)

Background. Optimization of antimicrobial stewardship is key to tackling antimicrobial resistance, which is exacerbated by overprescription of antibiotics in pediatric emergency departments (EDs). We described patterns of ...
Non-invasive diagnostics of pathogenic bacteria using a breath sampler in children with cystic fibrosis

van Aerde, Koen J.; Leegstraten, Aniek; van den Kieboom, Corné H.; Merkus, Peter; Sintnicolaas, Coosje; Simons, Sami O.; van der Flier, Michiel; de Groot, Ronald; de Jonge, Marien I. (IOP Publishing Ltd., 2022-10)

Cystic fibrosis (CF) is a common autosomal recessive disease causing thick, viscous secretions leading to pulmonary infections with pathogenic bacteria. As part of routine patient care, colonization and infection with these ...
Osteoarticular Infections in Pediatric Hospitals in Europe: A Prospective Cohort Study From the EUCLIDS Consortium

The EUCLIDS consortium (Frontiers Media S. A., 2022-05-04)

Background: Pediatric osteoarticular infections (POAIs) are serious diseases requiring early diagnosis and treatment. Methods: In this prospective multicenter cohort study, children with POAIs were selected from the European ...
External Validation of the Discriminative Validity of the ReSVinet Score and Development of Simplified ReSVinet Scores in Secondary Care

Sheikh, Zakariya; Potter, Ellie; Li, You; Drysdale, Simon B; Wildenbeest, Joanne G; Robinson, Hannah; McGinley, Joseph; Lin, Gu-Lung; Öner, Deniz; Aerssens, Jeroen; Justicia-Grande, Antonio José; Martinón-Torres, Federico; Pollard, Andrew J; Bont, Louis; Nair, Harish (Oxford University Press, 2024-03-15)

Background. There is no consensus on how to best quantify disease severity in infants with respiratory syncytial virus (RSV) and/or bronchiolitis; this lack of a sufficiently validated score complicates the provision of ...
Incorporating data from multiple endpoints in the analysis of clinical trials: example from RSV vaccines

Prunas, Ottavia; Willemsen, Joukje E; Bont, Louis; Pitzer, Virginia E; Warren, Joshua L; Weinberger, Daniel M (Lippincott Williams & Wilkins, 2024-01-01)

BACKGROUND: To meet regulatory approval, interventions must demonstrate efficacy against a primary outcome in randomized clinical trials. However, when there are multiple clinically relevant outcomes, selecting a single ...
Validity of clinical severity scores for respiratory syncytial virus: a systematic review

Sheikh, Zakariya; Potter, Ellie; Li, You; Cohen, Rachel A; Dos Santos, Gaël; Bont, Louis; Nair, Harish (Oxford University Press, 2024-03-15)

Background. Respiratory syncytial virus (RSV) is a widespread respiratory pathogen, and RSV-related acute lower respiratory tract infections are the most common cause of respiratory hospitalization in children <2 years of ...
The respiratory microbiome in childhood asthma

van Beveren, Gina J; Said, Hager; van Houten, Marlies A; Bogaert, Debby (Mosby Inc., 2023-12)

Asthma is the most prevalent noncommunicable disease in childhood, characterized by reversible airway constriction and inflammation of the lower airways. The respiratory tract consists of the upper and lower airways, which ...
Treatment of multiple traumatized adolescents by enhancing regulation skills and reducing trauma related symptoms: rationale, study design, and methods of randomized controlled trial (the Mars-study)

Knipschild, Rik; Klip, Helen; van Leeuwaarden, Doenja; van Onna, Mariken J R; Lindauer, Ramon J L; Staal, Wouter G; Bicanic, Iva A E; de Jongh, Ad (BioMed Central, 2023-09-04)

BACKGROUND: There is ongoing debate regarding the treatment of severe and multiple traumatized children and adolescents with post-traumatic stress disorder (PTSD). Many clinicians favor a phase-based treatment approach ...
CFTR Function Restoration upon Elexacaftor/Tezacaftor/Ivacaftor Treatment in Patient-Derived Intestinal Organoids with Rare CFTR Genotypes.

Lefferts, Juliet W; Bierlaagh, Marlou C; Kroes, Suzanne; Nieuwenhuijze, Natascha D A; Sonneveld van Kooten, Heleen N; Niemöller, Paul J; Verburg, Tibo F; Janssens, Hettie M; Muilwijk, Danya; van Beuningen, Sam F B; van der Ent, Cornelis K; Beekman, Jeffrey M (Multidisciplinary Digital Publishing Institute (MDPI), 2023-10)

Cystic fibrosis (CF) is caused by mutations in the Cystic Fibrosis Transmembrane conductance Regulator ( CFTR) gene. The combination of the CFTR modulators elexacaftor, tezacaftor, and ivacaftor (ETI) enables the effective ...
Academic institutions need to do more to support first-generation students

Hehakaya, Charisma (Nature Publishing Group, 2022-07-01)
Trajectories of Adherence to Home-Based Exercise Recommendations Among People With Low Back Pain: A Longitudinal Analysis

Arensman, Remco M; Heymans, Martijn W; Kloek, Corelien J J; Ostelo, Raymond J W G; Veenhof, Cindy; Koppenaal, Tjarco; Pisters, Martijn F (Oxford University Press, 2023-12-06)

Objective. This study aimed to examine the presence of distinct trajectories of adherence to home-based exercise recommendations among people with low back pain (LBP). This study also aimed to identify differences in ...
Characteristics and health outcomes associated with activation for self-management in patients with non-specific low back pain: A cross-sectional study

Koppenaal, T.; van der Heiden, J.; Kloek, C. J.J.; Arensman, R. M.; Ostelo, R. W.J.G.; Veenhof, C.; Pisters, M. F. (Elsevier, 2023-10)

Background: Research has shown that the course of non-specific low back pain (LBP) is influenced by, among other factors, patients' self-management abilities. Therefore, clinical guidelines recommend stimulation of ...
Long-Term Survival Associated with Direct Oral Feeding Following Minimally Invasive Esophagectomy: Results from a Randomized Controlled Trial (NUTRIENT II)

Geraedts, Tessa C M; Weijs, Teus J; Berkelmans, Gijs H K; Fransen, Laura F C; Kouwenhoven, Ewout A; van Det, Marc J; Nilsson, Magnus; Lagarde, Sjoerd M; van Hillegersberg, Richard; Markar, Sheraz R; Nieuwenhuijzen, Grard A P; Luyer, Misha D P (Multidisciplinary Digital Publishing Institute (MDPI), 2023-10-05)

Advancements in perioperative care have improved postoperative morbidity and recovery after esophagectomy. The direct start of oral intake can also enhance short-term outcomes following minimally invasive Ivor Lewis ...
A robust semi-automatic delineation workflow using denoised diffusion weighted magnetic resonance imaging for response assessment of patients with esophageal cancer treated with neoadjuvant chemoradiotherapy

den Boer, Robin; Siang, Kelvin Ng Wei; Yuen, Mandy; Borggreve, Alicia; Defize, Ingmar; van Lier, Astrid; Ruurda, Jelle; van Hillegersberg, Richard; Mook, Stella; Meijer, Gert (Elsevier, 2023-10)

BACKGROUND AND PURPOSE: Diffusion weighted magnetic resonance imaging (DW-MRI) can be prognostic for response to neoadjuvant chemotherapy (nCRT) in patients with esophageal cancer. However, manual tumor delineation is labor ...
Hospital practice variation in the proportion of patients with esophagogastric cancer discussed during an expert multidisciplinary team meeting

Luijten, Josianne C H B M; Vissers, Pauline A J; Geerts, Julie; Lemmens, Valery E P; van Hillegersberg, Richard; Beerepoot, Laurens; Walraven, Janneke E W; Curvers, Wouter; Voncken, Francine E M; van der Sangen, Maurice; Verhoeven, Rob H A; Nieuwenhuijzen, Grard A P (W.B. Saunders Ltd, 2023-09)

Background: Multidisciplinary team meetings (MDTM) and especially MDTMs in which expert centres are involved (expert MDTMs) are a key element in adequate cancer care. However, variation among hospitals in the proportion ...
A three-dimensional Magnetic Resonance Spin Tomography in Time-domain protocol for high-resolution multiparametric quantitative magnetic resonance imaging

Liu, Hongyan; van der Heide, Oscar; Versteeg, Edwin; Froeling, Martijn; Fuderer, Miha; Xu, Fei; van den Berg, Cornelis A T; Sbrizzi, Alessandro (John Wiley & Sons Inc., 2024-02)

Magnetic Resonance Spin TomogrAphy in Time-domain (MR-STAT) is a multiparametric quantitative MR framework, which allows for simultaneously acquiring quantitative tissue parameters such as T1, T2, and proton density from ...
High-dose alkylating chemotherapy in BRCA-altered triple-negative breast cancer: the randomized phase III NeoTN trial

Vliek, Sonja; Hilbers, Florentine S; van Werkhoven, Erik; Mandjes, Ingrid; Kessels, Rob; Kleiterp, Sieta; Lips, Esther H; Mulder, Lennart; Kayembe, Mutamba T; Loo, Claudette E; Russell, Nicola S; Vrancken Peeters, Marie-Jeanne T F D; Holtkamp, Marjo J; Schot, Margaret; Baars, Joke W; Honkoop, Aafke H; Vulink, Annelie J E; Imholz, Alex L T; Vrijaldenhoven, Suzan; van den Berkmortel, Franchette W P J; Meerum Terwogt, Jetske M; Schrama, Jolanda G; Kuijer, Philomeen; Kroep, Judith R; van der Padt-Pruijsten, Annemieke; Wesseling, Jelle; Sonke, Gabe S; Gilhuijs, Kenneth G A; Jager, Agnes; Nederlof, Petra; Linn, Sabine C (Elsevier, 2023-12)

Exploratory analyses of high-dose alkylating chemotherapy trials have suggested that BRCA1 or BRCA2-pathway altered (BRCA-altered) breast cancer might be particularly sensitive to this type of treatment. In this study, ...
ESMO Guidance for Reporting Oncology real-World evidence (GROW)

Castelo-Branco, L; Pellat, A; Martins-Branco, D; Valachis, A; Derksen, J W G; Suijkerbuijk, K P M; Dafni, U; Dellaporta, T; Vogel, A; Prelaj, A; Groenwold, R H H; Martins, H; Stahel, R; Bliss, J; Kather, J; Ribelles, N; Perrone, F; Hall, P S; Dienstmann, R; Booth, C M; Pentheroudakis, G; Delaloge, S; Koopman, M (Oxford University Press, 2023-12)
Increased endorsement of TRIPOD and other reporting guidelines by high impact factor journals: survey of instructions to authors

Heus, Pauline; Idema, Demy L; Kruithof, Emma; Damen, Johanna Aag; Verhoef-Jurgens, Maud S; Reitsma, Johannes B; Moons, Karel Gm; Hooft, Lotty (Elsevier, 2024-01)

OBJECTIVES: To assess the endorsement of reporting guidelines by high impact factor journals over the period 2017-2022, with a specific focus on the Transparent Reporting of a multivariable prediction model for Individual ...

Now showing items 8941-8960 of 40729