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Now showing items 8501-8520 of 40729

The diagnostic accuracy of local staging in colon cancer based on computed tomography (CT): evaluating the role of extramural venous invasion and tumour deposits

van den Berg, K; Wang, S; Willems, J M W E; Creemers, G J; Roodhart, J M L; Shkurti, J; Burger, J W A; Rutten, H J T; Beets-Tan, R G H; Nederend, J (Springer, 2024-02)

PURPOSE: The shift from adjuvant to neoadjuvant treatment in colon cancer demands the radiological selection of patients for systemic therapy. The aim of this study was to evaluate the accuracy of the CT-based TNM stage ...
Personalized neck irradiation guided by sentinel lymph node biopsy in patients with squamous cell carcinoma of the oropharynx, larynx or hypopharynx with a clinically negative neck: (Chemo)radiotherapy to the PRIMary tumor only. Protocol of the PRIMO study

van den Bosch, S; Takes, R P; de Ridder, M; de Bree, R; Al-Mamgani, A; Schreuder, W H; Hoebers, F J P; van Weert, S; Elbers, J B W; Hardillo, J A; Center Groningen, Groningen, The Netherlands, University; Plaat, B E C; de Jong, M A; Jansen, J C; Wellenstein, D J; van den Broek, G B; Vogel, W V; Arens, A I J; Kaanders, J H A M (Elsevier Ireland Ltd, 2024-01)

BACKGROUND: Elective neck irradiation (ENI) is performed in head and neck cancer patients treated with definitive (chemo)radiotherapy. The aim is to eradicate nodal metastases that are not detectable by pretreatment imaging ...
Mental healthcare utilization among head and neck cancer patients: A longitudinal cohort study

Jansen, Femke; Lissenberg-Witte, Birgit I.; Hardillo, Jose A.; Takes, Robert P.; de Bree, Remco; Lamers, Femke; Langendijk, Johannes A.; Leemans, C. René; Verdonck-de Leeuw, Irma M. (John Wiley & Sons Inc., 2024-01)

Objective: To investigate utilization of mental healthcare among head and neck cancer (HNC) patients from diagnosis to 2 years after treatment, in relation to psychological symptoms, mental disorders, need for mental ...
Solid: a novel similarity metric for mono-modal and multi-modal deformable image registration

Tzitzimpasis, Paris; Zachiu, Cornel; Raaymakers, Bas W; Ries, Mario G (IOP Publishing Ltd., 2024-01-07)

Medical image registration is an integral part of various clinical applications including image guidance, motion tracking, therapy assessment and diagnosis. We present a robust approach for mono-modal and multi-modal medical ...
Bayes and the Evidence Base: Re-Analyzing Trials Using Many Priors Does Not Contribute to Consensus

de Grooth, Harm-Jan; Cremer, Olaf L (American Thoracic Society, 2024-03-01)
Predicting adverse outcomes in adults with a community-acquired lower respiratory tract infection: a protocol for the development and validation of two prediction models for (i) all-cause hospitalisation and mortality and (ii) cardiovascular outcomes

Rijk, Merijn H; Platteel, Tamara N; Geersing, Geert-Jan; Hollander, Monika; Dalmolen, Bert L G P; Little, Paul; Rutten, Frans H; van Smeden, Maarten; Venekamp, Roderick P (2023-12-07)

BACKGROUND: Community-acquired lower respiratory tract infections (LRTI) are common in primary care and patients at particular risk of adverse outcomes, e.g., hospitalisation and mortality, are challenging to identify. ...
Relationship Between Pain and Delirium in Critically Ill Adults

Wu, Ting Ting; Vernooij, Lisette M; Duprey, Matthew S; Zaal, Irene J; Gélinas, Céline; Devlin, John W; Slooter, Arjen J C (Lippincott Williams & Wilkins, 2023-12-01)

OBJECTIVES: Although opioids are frequently used to treat pain, and are an important risk for ICU delirium, the association between ICU pain itself and delirium remains unclear. We sought to evaluate the relationship between ...
SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells

Sluimer, Lilian M.; Bullock, Esme; Rätze, Max A.K.; Enserink, Lotte; Overbeeke, Celine; Hornsveld, Marten; Brunton, Valerie G.; Derksen, Patrick W.B.; Tavares, Sandra (Company of Biologists Ltd, 2023-02)

High expression of the non-receptor tyrosine kinase FER is an independent prognostic factor that correlates with poor survival in breast cancer patients. To investigate whether the kinase activity of FER is essential for ...
Tacrolimus induces a pro-fibrotic response in donor-derived human proximal tubule cells dependent on common variants of the CYP3A5 and ABCB1 genes

Knops, Noël; Ramazani, Yasaman; De Loor, Henriëtte; Goldschmeding, Roel; Nguyen, Tri Q; van den Heuvel, Lambert P; Levtchenko, Elena; Kuypers, Dirk J (Oxford University Press, 2023-02-28)

BACKGROUND: Common genetic variants of the enzymes and efflux pump involved in tacrolimus disposition have been associated with calcineurin inhibitor nephrotoxicity, but their importance is unclear because of the multifactorial ...
CCN2 Activates RIPK3, NLRP3 Inflammasome, and NRF2/Oxidative Pathways Linked to Kidney Inflammation

Rayego-Mateos, Sandra; Marquez-Exposito, Laura; Basantes, Pamela; Tejedor-Santamaria, Lucia; Sanz, Ana B; Nguyen, Tri Q; Goldschmeding, Roel; Ortiz, Alberto; Ruiz-Ortega, Marta (Multidisciplinary Digital Publishing Institute (MDPI), 2023-08)

Inflammation is a key characteristic of both acute and chronic kidney diseases. Preclinical data suggest the involvement of the NLRP3/Inflammasome, receptor-interacting protein kinase-3 (RIPK3), and NRF2/oxidative pathways ...
Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials

Collaboration of Controlled Randomised Trials of Long-Term Oral Antithrombotic Agents After Spontaneous Intracranial Haemorrhage (COCROACH) (Elsevier Limited, 2023-12)

Background: The safety and efficacy of oral anticoagulation for prevention of major adverse cardiovascular events in people with atrial fibrillation and spontaneous intracranial haemorrhage are uncertain. We planned to ...
Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts

Alzheimer's Disease Neuroimaging Initiative (Elsevier, 2023)

INTRODUCTION: The spatial distribution of white matter hyperintensities (WMH) on MRI is often considered in the diagnostic evaluation of patients with cognitive problems. In some patients, clinicians may classify WMH ...
Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry

EORP EURO-ENDO Registry Investigators Group (Oxford University Press, 2022-07-01)

Aims: To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry. Methods ...
A Lumped Two-Compartment Model for Simulation of Ventricular Pump and Tissue Mechanics in Ischemic Heart Disease

Koopsen, Tijmen; Van Osta, Nick; Van Loon, Tim; Van Nieuwenhoven, Frans A; Prinzen, Frits W; Van Klarenbosch, Bas R; Kirkels, Feddo P; Teske, Arco J; Vernooy, Kevin; Delhaas, Tammo; Lumens, Joost (Frontiers Research Foundation, 2022-05-11)

Introduction: Computational modeling of cardiac mechanics and hemodynamics in ischemic heart disease (IHD) is important for a better understanding of the complex relations between ischemia-induced heterogeneity of myocardial ...
Continuation of fluoropyrimidine treatment with S-1 after cardiotoxicity on capecitabine- or 5-fluorouracil-based therapy in patients with solid tumours: a multicentre retrospective observational cohort study

Osterlund, P; Kinos, S; Pfeiffer, P; Salminen, T; Kwakman, J J M; Frödin, J-E; Shah, C H; Sorbye, H; Ristamäki, R; Halonen, P; Soveri, L M; Heervä, E; Ålgars, A; Bärlund, M; Hagman, H; McDermott, R; O'Reilly, M; Röckert, R; Liposits, G; Kallio, R; Flygare, P; Teske, A J; van Werkhoven, E; Punt, C J A; Glimelius, B (Elsevier, 2022-06)

BACKGROUND: Capecitabine- or 5-fluorouracil (5-FU)-based chemotherapy is widely used in many solid tumours, but is associated with cardiotoxicity. S-1 is a fluoropyrimidine with low rates of cardiotoxicity, but evidence ...
Candidate Plasma Biomarkers to Detect Anthracycline-Related Cardiomyopathy in Childhood Cancer Survivors: A Case Control Study in the Dutch Childhood Cancer Survivor Study

Leerink, Jan M; Feijen, Elizabeth A M; Moerland, Perry D; de Baat, Esmee C; Merkx, Remy; van der Pal, Helena J H; Tissing, Wim J E; Louwerens, Marloes; van den Heuvel-Eibrink, Marry M; Versluys, A Birgitta; Asselbergs, Folkert W; Sammani, Arjan; Teske, Arco J; van Dalen, Elvira C; van der Heiden-van der Loo, Margriet; van Dulmen-den Broeder, Eline; de Vries, Andrica C H; Kapusta, Livia; Loonen, Jacqueline; Pinto, Yigal M; Kremer, Leontien C M; Mavinkurve-Groothuis, Annelies M C; Kok, Wouter E M (Wiley-Blackwell, 2022-07-19)

Background Plasma biomarkers may aid in the detection of anthracycline-related cardiomyopathy (ACMP). However, the currently available biomarkers have limited diagnostic value in long-term childhood cancer survivors. This ...
Correction to: Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry (Infection, (2022), 50, 5, (1191-1202), 10.1007/s15010-022-01792-0)

EURO-ENDO Investigators group (Urban und Vogel, 2022-10-01)
Aortic regurgitation: A multimodality approach

Siani, Agnese; Perone, Francesco; Costantini, Pietro; Rodolfi, Sara; Muscogiuri, Giuseppe; Sironi, Sandro; Carriero, Serena; Pavon, Anna Giulia; van der Bilt, Ivo; van Rosendael, Philippe; Broekhuizen, Lysette; Teske, Arco; Cramer, Maarten Jan; Guglielmo, Marco (John Wiley & Sons Inc., 2022-10)

Aortic regurgitation (AR) is a common valvular pathology. Multimodality noninvasive cardiovascular imaging is routinely used to assess the mechanism of AR, degree, and its hemodynamic impact on the cardiovascular system. ...
Leveraging innovation, education, and technology for prevention and health equity: Proceedings from the cardiology oncology innovation ThinkTank 2021

Brown, Sherry-Ann; Berman, Generika; Logan, Jim; Sadler, Diego; Moudgil, Rohit; Patel, Brijesh; Scherrer-Crosbie, Marielle; Addison, Daniel; Cheng, Richard K; Teske, Arco J (Frontiers Media S. A., 2022-09-29)
The role of immune checkpoints in cardiovascular disease

Yousif, Laura I; Tanja, Anniek A; de Boer, Rudolf A; Teske, Arco J; Meijers, Wouter C (Frontiers Media S. A., 2022-10-03)

Immune checkpoint inhibitors (ICI) are monoclonal antibodies which bind to immune checkpoints (IC) and their ligands to prevent inhibition of T-cell activation by tumor cells. Currently, multiple ICI are approved targeting ...

Now showing items 8501-8520 of 40729