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Now showing items 6761-6780 of 40729

Final 192-Week Efficacy and Safety Results of the ADVANCE Trial, Comparing 3 First-line Antiretroviral Regimens

Sokhela, Simiso; Venter, Willem D.F.; Bosch, Bronwyn; Woods, Joana; McCann, Kaitlyn; Akpomiemie, Godspower; Chandiwana, Nomathemba; Mashabane, Nkuli; Tembo, Angela; Simmons, Bryony; Lalla-Edward, Samanta; Siedner, Mark J.; Sinxadi, Phumla; Hermans, Lucas; Fairlie, Lee; Vos, Alinda; Abrams, Elaine; Manne-Goehler, Jennifer M.; Moorhouse, Michelle; Clayden, Polly; Norris, Shane; Qavi, Ambar; Chersich, Matthew; Masenya, Masebole; Arulappan, Natasha; Hill, Andrew (Oxford University Press, 2024-03-01)

Background. ADVANCE compared 3 World Health Organization–recommended first-line regimens in participants with HIV who were antiretroviral naive. Methods. This randomized, open-label, noninferiority trial enrolled participants ...
Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis

Writing Group for the CKD Prognosis Consortium (American Medical Association, 2023-10-03)

Importance: Chronic kidney disease (low estimated glomerular filtration rate [eGFR] or albuminuria) affects approximately 14% of adults in the US. Objective: To evaluate associations of lower eGFR based on creatinine alone, ...
Loss of the HOPS complex disrupts early-to-late endosome transition, impairs endosomal recycling and induces accumulation of amphisomes

van der Beek, Jan; de Heus, Cilia; Sanza, Paolo; Liv, Nalan; Klumperman, Judith (American Society for Cell Biology, 2024-03-01)

The multisubunit HOPS tethering complex is a well-established regulator of lysosome fusion with late endosomes and autophagosomes. However, the role of the HOPS complex in other stages of endo-lysosomal trafficking is not ...
Footprint of publication selection bias on meta-analyses in medicine, environmental sciences, psychology, and economics

Bartoš, František; Maier, Maximilian; Wagenmakers, Eric-Jan; Nippold, Franziska; Doucouliagos, Hristos; Ioannidis, John P A; Otte, Willem M; Sladekova, Martina; Deresssa, Teshome K; Bruns, Stephan B; Fanelli, Daniele; Stanley, T D (John Wiley & Sons Inc., 2024-05)

Publication selection bias undermines the systematic accumulation of evidence. To assess the extent of this problem, we survey over 68,000 meta-analyses containing over 700,000 effect size estimates from medicine ...
Patient characteristics and reasons for discontinuation in a cardiovascular risk management programme in The Netherlands

Smits, Geert H.J.M.; van Doorn, Sander; Bots, Michiel L.; Hollander, Monika (BioMed Central Ltd., 2024-02-11)

Background: Since 2010, an increasing number of patients have participated in a nurse-led integrated cardiovascular risk management programme in the Netherlands. Because it is important to understand which patients discontinue ...
Dutch pharmacogenetics working group guideline for the gene-drug interaction of ABCG2, HLA-B and Allopurinol, and MTHFR, folic acid and methotrexate

van der Pol, Karel H.; Nijenhuis, Marga; Soree, Bianca; de Boer-Veger, Nienke J.; Buunk, Anne Marie; Guchelaar, Henk Jan; Risselada, Arne; van Schaik, Ron H.N.; Swen, Jesse J.; Touw, Daan; van der Weide, Jan; van Westrhenen, Roos; Deneer, Vera H.M.; Houwink, Elisa J.F.; Rongen, Gerard A. (Springer Nature, 2024-02)

The Dutch Pharmacogenetics Working Group (DPWG) aims to facilitate PGx implementation by developing evidence-based pharmacogenetics guidelines to optimize pharmacotherapy. This guideline describes the gene-drug interaction ...
Correction to: Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression (Molecular Psychiatry, (2024), 29, 2, (229-237), 10.1038/s41380-023-02318-2)

Argyelan, Miklos; Deng, Zhi-De; Ousdal, Olga Therese; Oltedal, Leif; Angulo, Brian; Baradits, Mate; Spitzberg, Andrew J; Kessler, Ute; Sartorius, Alexander; Dols, Annemiek; Narr, Katherine L; Espinoza, Randall; van Waarde, Jeroen A; Tendolkar, Indira; van Eijndhoven, Philip; van Wingen, Guido A; Takamiya, Akihiro; Kishimoto, Taishiro; Jorgensen, Martin B; Jorgensen, Anders; Paulson, Olaf B; Yrondi, Antoine; Péran, Patrice; Soriano-Mas, Carles; Cardoner, Narcis; Cano, Marta; van Diermen, Linda; Schrijvers, Didier; Belge, Jean-Baptiste; Emsell, Louise; Bouckaert, Filip; Vandenbulcke, Mathieu; Kiebs, Maximilian; Hurlemann, René; Mulders, Peter Cr; Redlich, Ronny; Dannlowski, Udo; Kavakbasi, Erhan; Kritzer, Michael D; Ellard, Kristen K; Camprodon, Joan A; Petrides, Georgios; Malhotra, Anil K; Abbott, Christopher C (Springer Nature, 2024-02)

Correction to: Molecular Psychiatryhttps://doi.org/10.1038/s41380-023-02318-2, published online 20 November 2023 In the original version of this article, the given and family names of Erhan Kavakbasi were incorrectly ...
Communication training for general practitioners aimed at improving antibiotic prescribing: a controlled before-after study in multicultural Dutch cities

Lescure, Dominique L A; Erdem, Özcan; Nieboer, Daan; Huijser van Reenen, Natascha; Tjon-A-Tsien, Aimée M L; van Oorschot, Wilbert; Brouwer, Rob; Vos, Margreet C; van der Velden, Alike W; Richardus, Jan Hendrik; Voeten, Hélène A C M (Frontiers Media S. A., 2024)
Childhood abuse v. neglect and risk for major psychiatric disorders

Alkema, Anne; Marchi, Mattia; Van Der Zaag, Jeroen A.J.; Van Der Sluis, Daniëlle; Warrier, Varun; Ophoff, Roel A.; Kahn, René S.; Cahn, Wiepke; Hovens, Jacqueline G.F.M.; Riese, Harriëtte; Scheepers, Floortje; Penninx, Brenda W.J.H.; Cecil, Charlotte; Oldehinkel, Albertine J.; Vinkers, Christiaan H.; Boks, Marco P.M.; Genetic Risk and Outcome of Psychosis (GROUP) Investigators (Cambridge University Press, 2024-06)

Background Childhood maltreatment (CM) is a strong risk factor for psychiatric disorders but serves in its current definitions as an umbrella for various fundamentally different childhood experiences. As first step toward ...
Cohort profile of BIGPROMISE: a perioperative biobank of a high-risk surgical population

Noordzij, Peter G.; Ruven, Henk Jt; Reniers, Ted; Idema, Rene N.; Thio, Maaike Sy; Cremer, Olaf L.; Hollema, Nynke; Smit, Kyra N.; Vernooij, Lisette M.; Dijkstra, Ineke M.; Rettig, Thijs Cd (BMJ Publishing Group, 2024-06-11)

Purpose Postoperative complications increase mortality, disability and costs. Advanced understanding of the risk factors for postoperative complications is needed to improve surgical outcomes. This paper discusses the ...
Is bewegen na de diagnose kanker veilig en effectief?

Hiensch, Anouk; Monninkhof, Evelyn; May, Anne (Bohn Stafleu van Loghum, 2024-07)
Determinants of Systemic SARS-CoV-2-Specific Antibody Responses to Infection and to Vaccination: A Secondary Analysis of Randomised Controlled Trial Data

Claus, Juana; Ten Doesschate, Thijs; Taks, Esther; Debisarun, Priya A; Smits, Gaby; van Binnendijk, Rob; van der Klis, Fiona; Verhagen, Lilly M; de Jonge, Marien I; Bonten, Marc J M; Netea, Mihai G; van de Wijgert, Janneke H H M (Multidisciplinary Digital Publishing Institute, 2024-06-20)

SARS-CoV-2 infections elicit antibodies against the viral spike (S) and nucleocapsid (N) proteins; COVID-19 vaccines against the S-protein only. The BCG-Corona trial, initiated in March 2020 in SARS-CoV-2-naïve Dutch ...
Association of autoantibodies with the IFN signature and NETosis in patients with systemic lupus erythematosus

Kaan, Ellen D.; Brunekreef, Tammo E.; Drylewicz, Julia; van den Hoogen, Lucas L.; van der Linden, Maarten; Leavis, Helen L.; van Laar, Jacob M.; van der Vlist, Michiel; Otten, Henny G.; Limper, Maarten (Elsevier, 2024-12)

Objective: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by a variety of disease symptoms and an unpredictable clinical course. To improve treatment outcome, stratification based on immunological ...
A Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel Consultations

Dutch multi-use disease modeling consortium (Adis International Ltd, 2024-07)

BACKGROUND: The current use of health economic decision models in HTA is mostly confined to single use cases, which may be inefficient and result in little consistency over different treatment comparisons, and consequently ...
Blood Pressure Variability and Plasma Biomarkers of Neuronal Injury and Alzheimer's Disease: A Clinic-Based Study of Patients with Diseases Along the Heart-Brain Axis

Heart-Brain Connection Consortium (2024)

Higher blood pressure variability (BPV) predisposes to cognitive decline. To investigate underlying mechanisms, we measured 24-h ambulatory BPV, nocturnal dipping and orthostatic hypotension in 518 participants with vascular ...
LANDMARK comparison of early outcomes of newer-generation Myval transcatheter heart valve series with contemporary valves (Sapien and Evolut) in real-world individuals with severe symptomatic native aortic stenosis: a randomised non-inferiority trial

LANDMARK trial investigators (Elsevier, 2024-06-22)

Background: Transcatheter aortic valve implantation is an established, guideline-endorsed treatment for severe aortic stenosis. Precise sizing of the balloon-expandable Myval transcatheter heart valve (THV) series with the ...
Design and implementation of multicenter pediatric and congenital studies with cardiovascular magnetic resonance: Big data in smaller bodies

DiLorenzo, Michael P; Lee, Simon; Rathod, Rahul H; Raimondi, Francesca; Farooqi, Kanwal M; Jain, Supriya S; Samyn, Margaret M; Johnson, Tiffanie R; Olivieri, Laura J; Fogel, Mark A; Lai, Wyman W; Renella, Pierangelo; Powell, Andrew J; Buddhe, Sujatha; Stafford, Caitlin; Johnson, Jason N; Helbing, Willem A; Pushparajah, Kuberan; Voges, Inga; Muthurangu, Vivek; Miles, Kimberley G; Greil, Gerald; McMahon, Colin J; Slesnick, Timothy C; Fonseca, Brian M; Morris, Shaine A; Soslow, Jonathan H; Grosse-Wortmann, Lars; Beroukhim, Rebecca S; Grotenhuis, Heynric B (Elsevier, 2024-06-01)

Cardiovascular magnetic resonance (CMR) has become the reference standard for quantitative and qualitative assessment of ventricular function, blood flow, and myocardial tissue characterization. There is a preponderance ...
Understanding changes in echocardiographic parameters at different ages following fetal growth restriction: a systematic review and meta-analysis

Van De Meent, Mette; Nijholt, Kirsten T.; Joemmanbaks, Shary C.A.; Kooiman, Judith; Schipper, Henk S.; Wever, Kimberley E.; Lely, A. Titia; Terstappen, Fieke (American Physiological Society, 2024-06)

Fetal growth restriction (FGR) increases cardiovascular risk by cardiac remodeling and programming. This systematic review and meta-analysis across species examines the use of echocardiography in FGR offspring at different ...
Dolphin CONTINUE: a multi-center randomized controlled trial to assess the effect of a nutritional intervention on brain development and long-term outcome in infants born before 30 weeks of gestation

Janson, E.; Koolschijn, P. C.M.P.; Schipper, L.; Boerma, T. D.; Wijnen, F. N.K.; de Boode, W. P.; van den Akker, C. H.P.; Licht-van der Stap, R. G.; Nuytemans, D. H.G.M.; Onland, W.; Obermann-Borst, S. A.; Dudink, J.; de Theije, C. G.M.; Benders, M. J.N.L.; van der Aa, N. E. (BioMed Central, 2024-06-07)

Background: Preterm born infants are at risk for brain injury and subsequent developmental delay. Treatment options are limited, but optimizing postnatal nutrition may improve brain- and neurodevelopment in these infants. ...
Impact of contractures on daily functioning in adolescents with spinal muscular atrophy: a qualitative study

Oude Lansink, I L B; Gorter, J W; van der Pol, W L; Bartels, B; Beelen, A (Informa Healthcare, 2024)

PURPOSE: Exploring the impact of contractures in adolescents and young adults (AYA) with spinal muscular atrophy (SMA) on daily functioning and participation and the impact of received contracture management. METHODS: We ...

Now showing items 6761-6780 of 40729