Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

Now showing items 6561-6580 of 40729

Exploring needs and requirements for a prototype device measuring physical activity in pediatric physical therapy: A qualitative study

Engels, Barbara; Kloek, Corelien J.J.; Sol, Marleen E.; Bolster, Eline A.M.; Kotte, Elles M.W.; Wittink, Harriët; Engelbert, Raoul H.H.; Gorter, Jan Willem; Bloemen, Manon A.T. (Public Library of Science, 2024-06)

Aims To analyze needs and requirements of Pediatric Physical Therapists (PPTs), parents, children and adolescents with and without developmental disabilities in the future use of an activity monitor prototype (AM-p) in ...
TWO-YEAR MORTALITY AND END-OF-LIFE DECISIONS AFTER TRAUMATIC SPINAL CORD INJURY: DATA FROM A LEVEL 1 TRAUMA CENTRE IN THE NETHERLANDS

Niemeyer, Menco J.S.; Peuker, Felix; Sadiqi, Said; Kerckhoffs, Monika C.; Houwert, R. Marijn; Van Wessem, Karlijn J.P.; Post, Marcel W.M.; Stolwijk, Janneke M. (Medical Journals Sweden AB, 2023)

Objective: Literature shows high in-hospital mortality rates following end-of-life decisions in patients with traumatic spinal cord injury. This study investi-gated 2-year mortality and end-of-life decisions in patients ...
Assessing accuracy of ChatGPT in response to questions from day to day pharmaceutical care in hospitals

van Nuland, Merel; Lobbezoo, Anne Fleur H.; van de Garde, Ewoudt M.W.; Herbrink, Maikel; van Heijl, Inger; Bognàr, Tim; Houwen, Jeroen P.A.; Dekens, Marloes; Wannet, Demi; Egberts, Toine; van der Linden, Paul D. (2024-09)

Background: The advent of Large Language Models (LLMs) such as ChatGPT introduces opportunities within the medical field. Nonetheless, use of LLM poses a risk when healthcare practitioners and patients present clinical ...
Ablative treatments for locally advanced pancreatic cancer: the CROSSFIRE trial

Westerhoff, Jasmijn Maria; Sanford, Nina Niu; Hall, William Adrian (Elsevier Limited, 2024-08)
CRISPR/Cas9-mediated genome editing of the thymidine kinase gene in a clinical HSV-1 isolate identifies F289S as novel acyclovir-resistant mutation

Zheng, Shuxuan; Verjans, Georges M.G.M.; Evers, Anouk; van den Wittenboer, Ellen; Tjhie, Jeroen H.T.; Snoeck, Robert; Wiertz, Emmanuel J.H.J.; Andrei, Graciela; van Kampen, Jeroen J.A.; Lebbink, Robert Jan (Elsevier, 2024-08)

Herpes simplex virus type 1 (HSV-1) is a neurotropic alphaherpesvirus that establishes a lifelong infection in sensory neurons of infected individuals, accompanied with intermittent reactivation of latent virus causing ...
A consensus molecular subtypes classification strategy for clinical colorectal cancer tissues

de Back, Tim R.; Wu, Tan; Schafrat, Pascale J.M.; Hoorn, Sanne Ten; Tan, Miaomiao; He, Lingli; van Hooff, Sander R.; Koster, Jan; Nijman, Lisanne E.; Vink, Geraldine R.; Beumer, Inès J.; Elbers, Clara C.; Lenos, Kristiaan J.; Sommeijer, Dirkje W.; Wang, Xin; Vermeulen, Louis (Life Science Alliance, LLC, 2024-08)

Consensus Molecular Subtype (CMS) classification of colorectal cancer (CRC) tissues is complicated by RNA degradation upon formalin-fixed paraffin-embedded (FFPE) preservation. Here, we present an FFPE-curated CMS classifier. ...
Erratum: Correction: A consensus molecular subtypes classification strategy for clinical colorectal cancer tissues (Life science alliance (2024) 7 8 PII: e202402889 DOI: 10.26508/lsa.202402730)

de Back, Tim R.; Wu, Tan; Schafrat, Pascale Jm; Ten Hoorn, Sanne; Tan, Miaomiao; He, Lingli; van Hooff, Sander R.; Koster, Jan; Nijman, Lisanne E.; Vink, Geraldine R.; Beumer, Inès J.; Elbers, Clara C.; Lenos, Kristiaan J.; Sommeijer, Dirkje W.; Wang, Xin; Vermeulen, Louis (Life Science Alliance, LLC, 2024-09-01)
The effect of guideline-based antimicrobial therapy on the outcome of fracture-related infections (EAT FRI Study)

Corrigan, Ruth; Sliepen, Jonathan; Rentenaar, Rob J; IJpma, Frank; Hietbrink, Falco; Atkins, Bridget L; Dudareva, Maria; Govaert, Geertje Am; McNally, Martin A; Wouthuyzen-Bakker, Marjan (W.B. Saunders Ltd, 2023-03)

AIM: This study investigated the compliance with a guideline-based antibiotic regimen on the outcome of patients surgically treated for a fracture-related infection (FRI). METHOD: In this international multicenter observational ...
Feasibility, safety, and efficacy of dietary or lifestyle interventions for hypothalamic obesity: A systematic review

Van Roessel, I. M.A.A.; Van Den Brink, M.; Dekker, J.; Ruitenburg-van Essen, B. G.; Tissing, W. J.E.; van Santen, H. M. (Churchill Livingstone, 2024-08)

Background & aims: A dysfunctional hypothalamus may result in decreased feelings of satiety (hyperphagia), decreased energy expenditure, and increased fat storage as a consequence of hyperinsulinemia. Hypothalamic dysfunction ...
Quality of MALDI-TOF mass spectra in routine diagnostics: results from an international external quality assessment including 36 laboratories from 12 countries using 47 challenging bacterial strains

ESGMD study group (Elsevier, 2023-02)

Objectives: Matrix assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (MS) is a widely used method for bacterial species identification. Incomplete databases and mass spectral quality (MSQ) ...
Clonidine for post-traumatic stress disorder: a systematic review of the current evidence

Marchi, Mattia; Grenzi, Pietro; Boks, Marco P. (Co-Action Publishing, 2024)

Background: Clonidine is a centrally acting anti-adrenergic agent that may have applications in post-traumatic stress disorder (PTSD), particularly for sleep.Objective: In this systematic review, we aimed to summarize the ...
The effectiveness of a protocol without routine radiographs for follow-up of adolescent idiopathic scoliosis patients (CURVE): a study protocol

De Kleuver, Marinus; Dutch AIS consortium (Informa Healthcare, 2024-06-17)

Background and purpose — Current follow-up proto-cols for adolescent idiopathic scoliosis (AIS) are based on consensus and consist of regular full-spine radiographs to monitor curve progression and surgical complications. ...
Comparing automated surveillance systems for detection of pathogen-related clusters in healthcare settings

Sim, Jean Xiang Ying; Pinto, Susanne; van Mourik, Maaike S.M. (BioMed Central Ltd., 2024-06-26)

BACKGROUND: Detection of pathogen-related clusters within a hospital is key to early intervention to prevent onward transmission. Various automated surveillance methods for outbreak detection have been implemented in ...
Vitamin K2 Supplementation in Hospitalised COVID-19 Patients: A Randomised Controlled Trial

Visser, Margot P.J.; Dofferhoff, Anton S.M.; van den Ouweland, Jody M.W.; de Jong, Pim A.; Zanen, Pieter; van Daal, Henny; Theeuwen, Eline B.; Kramers, Cornelis; Janssen, Rob; Walk, Jona (Multidisciplinary Digital Publishing Institute (MDPI), 2024-06)

Background: In observational studies, high levels of desphospho-uncarboxylated matrix gla protein (dp-ucMGP) that result from vitamin K deficiency were consistently associated with poor clinical outcomes during COVID-19. ...
Osteochondritis Dissecans of the Knee Associated With Mechanical Overload

van der Weiden, Goran S.; van Cruchten, Stijn; van Egmond, Nienke; Mastbergen, Simon C.; Husen, Martin; Saris, Daniël B.F.; Custers, Roel J.H. (SAGE Publications Inc., 2024-01)

Background: Osteochondritis dissecans (OCD) of the knee is a rare but potentially incapacitating disorder in which subchondral bone detaches, leading to an osteochondral fragment that can become unstable and progress into ...
Better spiritual support for people living with early stage dementia: Developing the diamond conversation model

Haufe, Marc; Leget, Carlo; Potma, Marieke; Teunissen, Saskia (SAGE Publications Ltd, 2024-01)

Background: People with early-stage dementia could benefit greatly from on-going spiritual support. However, health care professionals working in dementia care often do not have a clear idea of what such support might ...
How to provide existential and spiritual support to people with mild to moderate dementia and their loved ones. A pilot study

Haufe, Marc; Teunissen, Saskia; Leget, Carlo (Public Library of Science, 2024-03)

Background People with mild to moderate dementia and their loved ones may experience strong existential and spiritual challenges due to the disease. People with dementia could therefore benefit greatly from ongoing ...
‘It is important to feel invited’: what patients require when using the Utrecht Symptom Diary – 4 Dimensional, a qualitative exploration

Lormans, Tom; de Graaf, Everlien; de Vries, Sita; Leget, Carlo; Teunissen, Saskia (SAGE Publications Ltd, 2024-01-01)

Background: In palliative care, the Utrecht Symptom Diary – 4 Dimensional (USD-4D), a Dutch-adapted and validated patient-reported outcome measure, supports multidimensional symptom management through identification and ...
In vitro T cell responses to PD-1 blockade are reduced by IFN-α but do not predict therapy response in melanoma patients

Timmerman, Laura M.; Hensen, Lobke C.M.; van Eijs, Mick J.M.; Verheijden, Rik J.; Suijkerbuijk, Karijn P.M.; Meyaard, Linde; van der Vlist, Michiel; on behalf of the UNICIT consortium (Springer Science and Business Media Deutschland GmbH, 2024-09)

PD-1 blockade therapy has revolutionized melanoma treatment, but still not all patients benefit and pre-treatment identification of those patients is difficult. Increased expression of inflammatory markers such as interleukin ...
Association between progression of knee osteoarthritis pathology and gait changes over two years: Data from the IMI-APPROACH cohort

Jansen, Mylène; Hodgins, Diana; Mastbergen, Simon; Kloppenburg, M.; Blanco, Francisco J; Haugen, Ida K; Berenbaum, Francis; Eckstein, Felix; Roemer, Frank W; Wirth, Wolfgang (2024-09)

Objective Gait alterations in knee osteoarthritis (OA) patients are potentially related to structural progression of joint tissues, of which some are modifiable. The current objective was to determine whether progression ...

Now showing items 6561-6580 of 40729