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UMC Repository: Recent submissions

  • Signal intensity and volume of carotid intraplaque hemorrhage on magnetic resonance imaging and the risk of ipsilateral cerebrovascular events: The Plaque At RISK (PARISK) study 
    Nies, Kelly P.H.; Aizaz, Mueez; van Dam-Nolen, Dianne H.K.; Goring, Timothy C.D.; Schreuder, Tobien A.H.C.M.L.; van Orshoven, Narender P.; Postma, Alida A.; Bos, Daniel; Hendrikse, Jeroen; Nederkoorn, Paul; van der Geest, Rob; van Oostenbrugge, Robert J.; Mess, Werner H.; Kooi, M. Eline (Elsevier, 2024-12-01)
    Background: The Plaque At RISK (PARISK) study demonstrated that patients with a carotid plaque with intraplaque hemorrhage (IPH) have an increased risk of recurrent ipsilateral ischemic cerebrovascular events. It was ...
  • PROGnostic RolE of strain measurements in stress cardiac MRI in predicting major adverse cardiac events 
    Guglielmo, Marco; Fusini, Laura; Baessato, Francesca; Baggiano, Andrea; Mushtaq, Saima; Annoni, Andrea; Carerj, Maria Ludovica; Cilia, Francesco; Fazzari, Fabio; Formenti, Alberto; Gripari, Paola; Mancini, Maria Elisabetta; Marchetti, Francesca; Penso, Marco; Volpe, Alessandra; Tassetti, Luigi; Guaricci, Andrea Igoren; Muscogiuri, Giuseppe; Costantini, Pietro; van der Bilt, Ivo; van der Harst, Pim; Rabbat, Mark G; Rossi, Alexia; Fontana, Marianna; Pontone, Gianluca (Elsevier Ireland Ltd, 2024-10-01)
    Objectives: We aimed to investigate the role of feature-tracking (FT) strain in long-term risk stratification of patients with known or suspected coronary artery disease (CAD) who underwent stress cardiac MRI with dipyridamole; ...
  • Longitudinal associations of air pollution and green space with cardiometabolic risk factor clustering among children in the Netherlands 
    Liu, Mingwei; Vaartjes, Ilonca; Hoek, Gerard; Jaddoe, Vincent W V; Santos, Susana; Schreuder, Anton; Vrijkotte, Tanja G M; Grobbee, Diederick E; Timmermans, Erik J (Elsevier Limited, 2024-08)
    BACKGROUND: This study examines longitudinal associations of air pollution and green space with cardiometabolic risk among children in the Netherlands. METHODS: Three Dutch prospective cohorts with a total of 13,822 ...
  • Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy 
    Dias, Matheus Henrique; Friskes, Anoek; Wang, Siying; Fernandes Neto, Joao M.; van Gemert, Frank; Mourragui, Soufiane; Papagianni, Chrysa; Kuiken, Hendrik J.; Mainardi, Sara; Alvarez-Villanueva, Daniel; Lieftink, Cor; Morris, Ben; Dekker, Anna; van Dijk, Emma; Wilms, Lieke H.S.; da Silva, Marcelo S.; Jansen, Robin A.; Mulero-Sánchez, Antonio; Malzer, Elke; Vidal, August; Santos, Cristina; Salazar, Ramón; Wailemann, Rosangela A.M.; Torres, Thompson E.P.; De Conti, Giulia; Raaijmakers, Jonne A.; Snaebjornsson, Petur; Yuan, Shengxian; Qin, Wenxin; Kovach, John S.; Armelin, Hugo A.; Te Riele, Hein; van Oudenaarden, Alexander; Jin, Haojie; Beijersbergen, Roderick L.; Villanueva, Alberto; Medema, Rene H.; Bernards, Rene (American Association for Cancer Research Inc., 2024-07-01)
    Cancer homeostasis depends on a balance between activated oncogenic pathways driving tumorigenesis and engagement of stress response programs that counteract the inherent toxicity of such aberrant signaling. Although ...
  • Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi study 
    MASCC Mucositis Study Group (Elsevier, 2024-07)
    Background: Mucositis is a common and highly impactful side effect of conventional and emerging cancer therapy and thus the subject of intense investigation. Although common practice, mucositis assessment is heterogeneously ...
  • Connecting through ISEV's developing social media landscape 
    Driedonks, Tom A P; Goberdhan, Deborah C I; Mohanty, Sujata; Williams, Sarah; Nieuwland, Rienk; Witwer, Kenneth W; Torrecilhas, Ana Claudia (John Wiley & Sons Inc., 2024-07-08)
  • Implementation of long-acting cabotegravir and rilpivirine: primary results from the perspective of staff study participants in the Cabotegravir And Rilpivirine Implementation Study in European Locations 
    Gutner, Cassidy A.; Hocqueloux, Laurent; Jonsson-Oldenbüttel, Celia; Vandekerckhove, Linos; van Welzen, Berend J.; Slama, Laurence; Crusells-Canales, María; Sierra, Julián Olalla; DeMoor, Rebecca; Scherzer, Jenny; Ait-Khaled, Mounir; Bontempo, Gilda; Gill, Martin; Patel, Natasha; D'Amico, Ronald; Hove, Kai; Baugh, Bryan; Barnes, Nicola; Hadi, Monica; Low, Emma L.; Anand, Savita Bakhshi; Hamilton, Alison; Garges, Harmony P.; Czarnogorski, Maggie (International AIDS Society, 2024-07)
    Introduction: Cabotegravir plus rilpivirine (CAB + RPV) is the first complete long-acting (LA) regimen recommended for maintaining HIV-1 virological suppression. Cabotegravir And Rilpivirine Implementation Study in European ...
  • Mechanism-based interventions for ASD cannot be implemented using conventional trial designs 
    Sprengers, Jan J.; Geertjens, Lisa; Bruining, Hilgo (John Wiley & Sons Inc., 2024-02)
  • Adjuvant Hyperthermic Intraperitoneal Chemotherapy in Patients With Locally Advanced Colon Cancer (COLOPEC): 5-Year Results of a Randomized Multicenter Trial 
    van Grevenstein, Wilhemina M.U.; COLOPEC collaborators group (Lippincott Williams & Wilkins, 2024-01-10)
    Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are ...
  • Exploring silk fibroin aerogels via different coagulation approaches 
    Viola, Martina; Chartier, Coraline; Mihajlovic, Marko; Buwalda, Sijtze; Pradille, Christophe; Budtova, Tatiana; Vermonden, Tina (Elsevier Limited, 2024-02-07)
    Aerogels are highly porous nanostructured materials with a high specific surface area, a very low density and a low thermal conductivity. Bio-aerogels, prepared from biopolymers, have gained interest for biomedical ...
  • Impact of fatigue in surgeons on performance and patient outcome: systematic review 
    Reijmerink, Iris M.; van der Laan, Maarten J.; Götz Wietasch, J. K.; Hooft, Lotty; Cnossen, Fokie (John Wiley & Sons Inc., 2024-01-01)
    Background: While fatigue is an inevitable aspect of performing surgical procedures, lack of consensus remains on its effect on surgical performance. The aim of this systematic review was to assess the effect of non-muscular ...
  • Identifying risk factors and analyzing reconstructive outcomes in patients with lower-extremity soft-tissue sarcoma 
    Krijgh, David D.; Smith, J. Michael; Tilney, Gordon; Lyu, Heather; Traweek, Raymond S.; Witt, Russell G.; Roubaud, Margaret J.; Correa, Arlene M.; Roland, Christina L.; Mericli, Alexander F. (Churchill Livingstone, 2024-02)
    Purpose: Reconstructing defects after resecting soft-tissue sarcoma (STS) can be challenging. The aim of this retrospective study was to analyze the reconstructive outcomes and identify the potential risk factors in patients ...
  • Early COVID-19 vaccine effectiveness of XBB.1.5 vaccine against hospitalisation and admission to intensive care, the Netherlands, 9 October to 5 December 2023 
    van Werkhoven, C. Henri; Valk, Anne Wil; Smagge, Bente; de Melker, Hester E.; Knol, Mirjam J.; Hahné, Susan JM; van den Hof, Susan; de Gier, Brechje (Centre Europeen pour la Surveillance Epidemiologique du SIDA, 2024-01-04)
    We present early vaccine effectiveness (VE) estimates of the 2023 seasonal COVID-19 XBB.1.5 vaccine against COVID-19 hospitalisation and admission to an intensive care unit (ICU) in previously vaccinated adults≥60 years ...
  • CRUSE®—An innovative mobile application for patient monitoring and management in chronic spontaneous urticaria 
    Neisinger, Sophia; Sousa Pinto, Bernardo; Ramanauskaite, Aiste; Bousquet, Jean; Weller, Karsten; Metz, Martin; Magerl, Markus; Kocatürk, Emek; Cherrez-Ojeda, Ivan; Gimenez-Arnau, Ana M.; Parisi, Claudio Alberto S.; Altrichter, Sabine; Ensina, Luis Felipe; Bouillet, Laurence; Asero, Riccardo; Gonçalo, Margarida; Guillet, Carole; Rutkowski, Krzysztof; Bernstein, Jonathan A.; Hardin, Hannah; Godse, Kiran; Brzoza, Zenon; Sousa, Jose Ignacio Larco; Thomsen, Simon Francis; van Doorn, Martijn; Hide, Michihiro; Ye, Young Min; Vanderse, Staffan; Lapiņa, Lāsma; Peter, Jonny; Zhao, Zuotao; Han, Lianyi; Nasr, Iman; Rockmann-Helmbach, Heike; Sørensen, Jennifer Astrup; Kara, Rabia Öztaş; Kurjāne, Natalja; Kurchenko, Andrii I.; Kaidashev, Igor; Tsaryk, Vladyslav; Stepanenko, Roman; Maurer, Marcus (BioMed Central, 2024-01)
    Background: Chronic spontaneous urticaria (CSU) is unpredictable and can severely impair patients' quality of life. Patients with CSU need a convenient, user-friendly platform to complete patient-reported outcome measures ...
  • Ethnic and socioeconomic inequalities in air pollution exposure: a cross-sectional analysis of nationwide individual-level data from the Netherlands 
    van den Brekel, Lieke; Lenters, Virissa; Mackenbach, Joreintje D.; Hoek, Gerard; Wagtendonk, Alfred; Lakerveld, Jeroen; Grobbee, Diederick E.; Vaartjes, Ilonca (Elsevier, 2024-01)
    Background: Air pollution contributes to a large disease burden and some populations are disproportionately exposed. We aimed to evaluate ethnic and socioeconomic differences in exposure to air pollution in the Netherlands. ...
  • Molecular and Phenotypic Characterization of the RORB-Related Disorder 
    Gokce-Samar, Zeynep; Vetro, Annalisa; De Bellescize, Julitta; Pisano, Tiziana; Monteiro, Laloe; Penaud, Noémie; Korff, Christian M.; Fluss, Joel; Marini, Carla; Cesaroni, Elisabetta; Alvarez, Blanca Mercedes; Sanlaville, Damien; Chatron, Nicolas; Arzimanoglou, Alexis A.; Labalme, Audrey; Cuddapah, Vishnu A.; Ruggiero, Sarah M.; Lecoquierre, Francois; Nicolas, Gael; Marie, Guerrot Anne; Lebas, Axel; Testard, Herve O.; Helbig, Katherine L.; Ruiz, Anna; Ngoh, Adeline; Kurian, Manju A.; Reid, Kimberley; Spaull, Robert; Joset, Pascal; Ramantani, Georgia; Steindl, Katharina; Krenn, Martin; Gerstl, Lucia; Vieker, Silvia; Craiu, Dana; Pendziwiat, Manuela; Haldeman-Englert, Chad; Kanivets, Ilya; Romanova, Irina; Rajan, Deepa S.; Rosenfeld, Jill A.; Au, Margaret; Grand, Katheryn; Graham, John M.; Isapof, Arnaud; Villeneuve, Nathalie; Smol, Thomas; Caumes, Roseline; Zacher, Pia; Neuser, Sonja; Tinschert, Sigrid; Platzer, Konrad; Bartolomaeus, Tobias; Mohnke, Ines; Radtke, Maximilian; Jamra, Rami Abou; Helbig, Ingo; Jansen, Floortje E.; Koop, Klaas; Rudolf, Gabrielle; Küry, Sebastien; Courchet, Julien; Guerrini, Renzo; Lesca, Gaetan (Lippincott Williams & Wilkins, 2024-01-23)
    Background and ObjectivesHeterozygous variants in RAR-related orphan receptor B (RORB) have recently been associated with susceptibility to idiopathic generalized epilepsy. However, few reports have been published so far ...
  • Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children 
    Spaan, András N.; COVID Clinicians; GEN-COVID Study Group; COVID Human Genetic Effort (Rockefeller University Press, 2024)
    We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19 pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-α2 in 10 patients: IFN-α2 only in three, IFN-α2 plus IFN-ω in five, and ...
  • A comparison of hyperparameter tuning procedures for clinical prediction models: A simulation study 
    Dunias, Zoë S.; Van Calster, Ben; Timmerman, Dirk; Boulesteix, Anne Laure; van Smeden, Maarten (John Wiley & Sons Inc., 2024-03-15)
    Tuning hyperparameters, such as the regularization parameter in Ridge or Lasso regression, is often aimed at improving the predictive performance of risk prediction models. In this study, various hyperparameter tuning ...
  • Neural stem cell homeostasis is affected in cortical organoids carrying a mutation in Angiogenin 
    Ferguson, Ross; van Es, Michael A.; van den Berg, Leonard H.; Subramanian, Vasanta (John Wiley & Sons Inc., 2024-04)
    Mutations in Angiogenin (ANG) and TARDBP encoding the 43 kDa transactive response DNA binding protein (TDP-43) are associated with amyotrophic lateral sclerosis and frontotemporal dementia (ALS-FTD). ANG is neuroprotective ...
  • Shared decision-making with older adults with cancer: Adaptation of a model through literature review and expert opinion 
    Gans, Emma A.; Pieterse, Arwen H.; Klapwijk, Maartje S.; van Stiphout, Feikje; van Steenbergen, Irma J.; Portielje, Johanneke E.A.; de Groot, Janke F.; van Munster, Barbara C.; van den Bos, Frederiek (John Wiley & Sons Inc., 2024-01)
    Objective: To provide a literature overview of characteristics of Shared Decision Making (SDM) with specific importance to the older adult population with cancer and to tailor an existing model of SDM in patients with ...