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Now showing items 6181-6200 of 40729

Histone deacetylase inhibition sensitizes p53-deficient B-cell precursor acute lymphoblastic leukemia to chemotherapy

Cox, Willem P.J.; Evander, Nils; van Ingen Schenau, Dorette S.; Stoll, Gawin R.; Anderson, Nadia; de Groot, Lieke; Grünewald, Kari J.T.; Hagelaar, Rico; Butler, Miriam; Kuiper, Roland P.; van der Meer, Laurens T.; van Leeuwen, Frank N. (Ferrata Storti Foundation, 2024-06)

In pediatric acute lymphoblastic leukemia (ALL), mutations/deletions affecting the TP53 gene are rare at diagnosis. However, at relapse about 12% of patients show TP53 aberrations, which are predictive of a very poor ...
Hysterosalpingo-foam sonography versus hysterosalpingography during fertility work-up: an economic evaluation alongside a randomized controlled trial

Kamphuis, Danah; van Eekelen, Rik; van Welie, Nienke; Dreyer, Kim; van Rijswijk, Joukje; van Hooff, Machiel H.A.; de Bruin, Jan Peter; Verhoeve, Harold R.; Mol, Femke; van Baal, Wilhelmina M.; Traas, Maaike A.F.; van Peperstraten, Arno M.; Manger, Arentje P.; Gianotten, Judith; de Koning, Cornelia H.; Koning, Aafke M.H.; Bayram, Neriman; van der Ham, David P.; Vrouenraets, Francisca P.J.M.; Kalafusova, Michaela; van de Laar, Bob I.G.; Kaijser, Jeroen; Lambeek, Arjon F.; Meijer, Wouter J.; Broekmans, Frank J.M.; Valkenburg, Olivier; van der Voet, Lucy F.; van Disseldorp, Jeroen; Lambers, Marieke J.; Tros, Rachel; Lambalk, Cornelis B.; Stoker, Jaap; van Wely, Madelon; Bossuyt, Patrick M.M.; Mol, Ben Willem J.; Mijatovic, Velja (Oxford University Press, 2024-06-01)

STUDY QUESTION: What are the costs and effects of tubal patency testing by hysterosalpingo-foam sonography (HyFoSy) compared to hysterosalpingography (HSG) in infertile women during the fertility work-up? SUMMARY ANSWER: ...
NOTCH1 fusions in pediatric T-cell lymphoblastic lymphoma: A high-risk subgroup with CCL17 (TARC) levels as diagnostic biomarker

Kroeze, Emma; Kleisman, Michelle M.; Kester, Lennart A.; Scheijde-Vermeulen, Marijn A.; Sonneveld, Edwin; Buijs-Gladdines, Jessica G.C.; Hagleitner, Melanie M.; Meyer-Wentrup, Friederike A.G.; Veening, Margreet A.; Beishuizen, Auke; Meijerink, Jules P.P.; Loeffen, Jan L.C.; Kuiper, Roland P. (Wolters Kluwer Health, 2024-07)

Twenty percent of children with T-cell lymphoblastic lymphoma (T-LBL) will relapse and have an extremely poor outcome. Currently, we can identify a genetically low-risk subgroup in pediatric T-LBL, yet these high-risk ...
Morbidity and trends in length of hospitalisation of very and extremely preterm infants born between 2008 and 2021 in the Netherlands: A cohort study

De Bijl-Marcus, Karen; Benders, Manon J.N.L.; Dudink, Jeroen; Ahaus, Kees; Kahlmann, Marijn; Groenendaal, Floris (BMJ Publishing Group, 2024-06-04)

Objectives This study investigated changes in the length of stay (LoS) at a level III/IV neonatal intensive care unit (NICU) and level II neonatology departments until discharge home for very preterm infants and identified ...
An exploratory open-label multicentre phase I/II trial evaluating the safety and efficacy of postnatal or prenatal and postnatal administration of allogeneic expanded fetal mesenchymal stem cells for the treatment of severe osteogenesis imperfecta in infants and fetuses: The BOOSTB4 trial protocol

Sagar, Rachel L.; Åström, Eva; Chitty, Lyn S.; Crowe, Belinda; David, Anna L.; Devile, Catherine; Forsmark, Annabelle; Franzen, Vera; Hermeren, Göran; Hill, Melissa; Johansson, Mats; Lindemans, Caroline; Lindgren, Peter; Nijhuis, Wouter; Oepkes, Dick; Rehberg, Mirko; Sahlin, Nils Eric; Sakkers, Ralph; Semler, O.; Sundin, Mikael; Walther-Jallow, Lilian; Verweij, E. J.T.Joanne; Westgren, Magnus; Götherström, Cecilia (BMJ Publishing Group, 2024-06-04)

Introduction Severe osteogenesis imperfecta (OI) is a debilitating disease with no cure or sufficiently effective treatment. Mesenchymal stem cells (MSCs) have good safety profile, show promising effects and can form bone. ...
Brain-age prediction: Systematic evaluation of site effects, and sample age range and size

ENIGMA Lifespan Working Group (Wiley-Liss Inc., 2024-07-15)

Structural neuroimaging data have been used to compute an estimate of the biological age of the brain (brain-age) which has been associated with other biologically and behaviorally meaningful measures of brain development ...
Cervical cancer screening outcomes for HIVpositive women in the Lubombo and Manzini regions of Eswatini-Prevalence and predictors of a positive visual inspection with acetic acid (VIA) screen

Mapaona, Rufaro; Williams, Victor; Musarapasi, Normusa; Kibwana, Sharon; Maseko, Thokozani; Chekenyere, Rhinos; Gumbo, Sidumo; Mdluli, Phetsile; Byarugaba, Hugben; Galagedera, Dileepa; Mafukidze, Arnold; Hurtado-De-Mendoza, Alejandra; Adsul, Prajakta; Bongomin, Pido; Loffredo, Christopher; Dlamini, Xolisile; Bazira, Deus; Ojoo, Sylvia; Haumba, Samson (Public Library of Science, 2024-04)

This study aimed to describe the prevalence and predictors of a positive VIA (visual inspection with acetic acid) cervical cancer screening test in women living with human immunodeficiency virus (HIV). We retrospectively ...
Regional disparities in the use of intensive chemotherapy for AML in the Netherlands: Does it influence survival?

Kaplan, Z. L.Rana; Van Leeuwen, Nikki; Van Klaveren, David; Visser, Otto; Posthuma, Eduardus F.M.; Van Lammeren-Venema, Danielle; Snijders, Tjeerd J.F.; Van Elssen, Catharina H.M.J.; Van Rhenen, Anna; Von Dem Borne, Peter A.; Blijlevens, Nicole M.A.; Cornelissen, Jan J.; Raaijmakers, Marc H.G.P.; Van De Loosdrecht, Arjan A.; Huls, Gerwin; Lemmens, Valery E.P.P.; Lingsma, Hester F.; Dinmohamed, Avinash G. (BMJ Publishing Group, 2024-07-05)

Objective Acute myeloid leukaemia (AML) prognosis is enhanced with intensive remission induction chemotherapy (ICT) in eligible patients. However, ICT eligibility perceptions may differ among healthcare professionals. This ...
Perspectives and Update on the Global Shortage of Verteporfin (Visudyne®)

Sirks, Marc J.; Subhi, Yousif; Rosenberg, Noa; Hollak, Carla E.M.; Boon, Camiel J.F.; Diederen, Roselie M.H.; Yzer, Suzanne; Ossewaarde-van Norel, Jeannette; de Jong-Hesse, Yvonne; Schlingemann, Reinier O.; Moss, Rob J.; van Dijk, Elon H.C. (Springer London, 2024-07)

An ongoing global shortage of verteporfin (Visudyne®) limits the treatment possibilities for several chorioretinal diseases, including central serous chorioretinopathy, choroidal hemangioma, and polypoidal choroidal ...
Outpatient and Ambulatory Extended Recovery Robotic Hepatectomy: Multinational Study of 307 Cases

Park, James O.; Lafaro, Kelly; Hagendoorn, Jeroen; Melstrom, Laleh; Gerhards, Michael F.; Görgec, Burak; Marsman, Hendrik A.; Thornblade, Lucas W.; Pilz da Cunha, Gabriela; Yang, Frank F.; Labadie, Kevin P.; Sham, Jonathan G.; Swijnenburg, Rutger Jan; He, Jin; Fong, Yuman (Elsevier, 2024-07-01)

BACKGROUND: For open minor hepatectomy, morbidity and recovery are dominated by the incision. The robotic approach may transform this "incision dominant procedure" into a safe outpatient procedure. STUDY DESIGN: We audited ...
Lateralized modulation of cortical beta power during human gait is related to arm swing

Borhanazad, Marzieh; van Wijk, Bernadette C.M.; Buizer, Annemieke I.; Kerkman, Jennifer N.; Bekius, Annike; Dominici, Nadia; Daffertshofer, Andreas (Elsevier, 2024-07-19)

Human gait is a complex behavior requiring dynamic control of upper and lower extremities that is accompanied by cortical activity in multiple brain areas. We investigated the contribution of beta (15–30 Hz) and gamma ...
Preventie van efficiënte transmissie van zoönotische ziektekiemen tussen veehouderijbedrijven

Hagenaars, Thomas J; de Jong, M.C.M.; van Schaik, G.; Fischer, Egil A J; Bonten, Marc; Koopmans, Marion P G; Klinkenberg, Don; Kretzschmar, Mirjam; van der Poel, Wim H M; Smit, Lidwien AM; Stegeman, Arjan; Heederik, Dick (Utrecht University, 2022-10-10)
Measurement and Modeling: Infectious Disease Modeling

Kretzschmar, Mirjam (Elsevier, 2017)

After some historical remarks about the development of mathematical theory for infectious disease dynamics, we introduce a basic mathematical model for the spread of an infection with immunity. The concepts of the model ...
Infectious Disease Epidemiology

Straif-Bourgeois, Susanne; Tonzel, Julius L.; Kretzschmar, Mirjam; Ratard, Raoult (Springer, 2023-09-11)

Most textbooks dealing with the epidemiology of infectious diseases address the epidemiological features (also called biology) of specific infectious diseases. In this chapter, the focus is placed on the concepts and methods ...
Sex-related Outcomes After Thoracic Endovascular Repair for Intact Isolated Descending Thoracic Aortic Aneurysm: A Retrospective Cohort Study

Allievi, Sara; Rastogi, Vinamr; Yadavalli, Sai Divya; Mandigers, Tim J.; Gomez-Mayorga, Jorge L.; Deery, Sarah E.; Lo, Ruby C.; Verhagen, Hence J.M.; Trimarchi, Santi; Schermerhorn, Marc L. (Lippincott Williams & Wilkins, 2024-07-01)

Objective: The aim of this study was to evaluate the association between sex and outcomes following thoracic endovascular aortic repair (TEVAR) for intact isolated descending thoracic aortic aneurysms (iiDTAA). Background: ...
Lifestyle factors and metabolomic aging biomarkers: Meta-analysis of cross-sectional and longitudinal associations in three prospective cohorts

Kuiper, L. M.; Smit, A. P.; Bizzarri, D.; van den Akker, E. B.; Reinders, M. J.T.; Ghanbari, M.; van Rooij, J. G.J.; Voortman, T.; Rivadeneira, F.; Dollé, M. E.T.; Herber, G. C.M.; Rietman, M. L.; Picavet, H. S.J.; van Meurs, J. B.J.; Verschuren, W. M.M. (Elsevier Ireland Ltd, 2024-08)

Biological age uses biophysiological information to capture a person's age-related risk of adverse outcomes. MetaboAge and MetaboHealth are metabolomics-based biomarkers of biological age trained on chronological age and ...
Clinical Validation of Multiparametric Ultrasound for Detecting Clinically Significant Prostate Cancer Using Computer-Aided Diagnosis: A Direct Comparison with the Magnetic Resonance Imaging Pathway

van den Kroonenberg, Daniel L.; Jager, Auke; Garrido-Utrilla, Anna; Reitsma, Johannes B.; Postema, Arnoud W.; Beerlage, Harrie P.; Oddens, Jorg R. (Elsevier, 2024-08)

We present the protocol for a study testing the hypothesis that a computer-aided diagnosis (CAD) system for three-dimensional multiparametric ultrasound (3D mpUS) is noninferior to magnetic resonance imaging (MRI) in guiding ...
Occupational exposure to benzene and mortality risk of lymphohaematopoietic cancers in the Swiss National Cohort

Ge, Calvin; Spoerri, Adrian; Egger, Matthias; Rothman, Nathaniel; Lan, Qing; Huss, Anke; Vermeulen, Roel; for the Swiss National Cohort (Finnish Institute of Occupational Health, 2024-07-01)

Objectives Previous studies established a causal relationship between occupational benzene exposure and acute myeloid leukemia (AML). However, mixed results have been reported for associations between benzene exposure and ...
Healthcare professionals as change agents: Factors influencing bottom-up, personal initiatives on appropriate care, a qualitative study in the Netherlands

Krijgsheld, Marcel; Schmidt, Eduard (J E.T.).; Levels, Edwin; Schuurmans, Marieke (M J.). (Elsevier Ireland Ltd, 2024-09)

Introduction: Healthcare organisations face multiple challenges, often conceptualised as appropriate care. It requires change on different levels: healthcare systems (macro), healthcare organisations (meso), and healthcare ...
Recurrence and Survival after Minimally Invasive and Open Esophagectomy for Esophageal Cancer: A Post Hoc Analysis of the Ensure Study

Henckens, Sofie P.G.; Schuring, Nannet; Elliott, Jessie A.; Johar, Asif; Markar, Sheraz R.; Gantxegi, Amaia; Lagergren, Pernilla; Hanna, George B.; Pera, Manuel; Reynolds, John V.; Van Berge Henegouwen, Mark I.; Gisbertz, Suzanne S.; ENSURE Study Group (Lippincott Williams & Wilkins, 2024-08-01)

Objective: To determine the impact of operative approach [open (OE), hybrid minimally invasive (HMIE), and total minimally invasive (TMIE) esophagectomy] on operative and oncologic outcomes for patients treated with curative ...

Now showing items 6181-6200 of 40729