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Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans

COVIDSurg Collaborative (John Wiley & Sons Inc., 2020-10-01)

Background: The COVID-19 pandemic has disrupted routine hospital services globally. This study estimated the total number of adult elective operations that would be cancelled worldwide during the 12 weeks of peak disruption ...
Adult patient diagnosed with Muckle-Wells syndrome, antiphospholipid syndrome and glomerular haematuria

Blokland, Sofie L.M.; Limper, Maarten; Van Eerde, Albertien M.; Remmelts, Hilde H.F. (BMJ Publishing Group, 2024-01-08)

Muckle-Wells syndrome (MWS) is a genetic periodic fever syndrome characterised by urticaria, fever and malaise starting in childhood with the development of perceptive hearing loss and risk of amyloidosis later in life. ...
Prospective observational cohort study on grading the severity of postoperative complications in global surgery research

International Surgical Outcomes Study (ISOS) group (John Wiley & Sons Inc., 2019-01)

BACKGROUND: The Clavien-Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. ...
Nature and Challenges in the Teaching of Anatomy from a Global Perspective

Chang Chan, Ana (Utrecht University, 2024-08-30)

Human anatomy has played a central role in the evolution of medical sciences. During the 20th century, several changes occurred in anatomy in both science and education. To meet current health needs, low-and-middle-income ...
Bringing clinical research to patients: Ethical aspects of decentralized clinical trials

van Rijssel, Tessa (Utrecht University, 2024-09-17)

Clinical trials with human participants are essential for determining the efficacy and safety of novel drugs and medical treatments. The development of novel drugs and treatments through various phases of clinical trials ...
The effect of postoperative intravenous iron in anaemic, older cardiac surgery patients on disability-free survival (AGE ANEMIA study): study protocol for a multi-centre, double-blind, randomized, placebo-controlled trial

Smoor, R M; Rettig, T C D; Vernooij, L M; Groenewegen, E M; van Dongen, H P A; Noordzij, P G (BioMed Central, 2023-10-26)

Background: Postoperative anaemia is common in older cardiac surgery patients and often caused by iron deficiency. Anaemia may negatively affect recovery after cardiac surgery. This study aims to determine the efficacy of ...
Postoperative Myocardial Injury and Inflammatory Biomarkers in Patients Undergoing Vascular Surgery: A Subanalysis of the Platelet Reactivity and Postoperative Myocardial Injury after Major Vascular Surgery (PROMISE) Study

Zheng, Kailiang; Bor, Willem L; Kelder, Johannes C; Hackeng, Chris M; Kropman, Rogier H J; Ten Berg, Jurrien M; Noordzij, Peter G (Elsevier, 2024-05)

BACKGROUND: Postoperative myocardial injury (PMI) is associated with morbidity and mortality, but the aetiology remains unclear. We studied whether PMI is associated with perioperative systemic inflammation. The objective ...
Overcoming challenges in advanced melanoma treatment: The value of real-world data

van Not, Olivier (Utrecht University, 2024-09-03)

Each year, approximately 800 to 900 patients in the Netherlands are diagnosed with metastatic (i.e. unresectable) melanoma. Several new systemic therapies have become available for the treatment of unresectable melanoma. ...
Harmonizing and Optimizing CT Perfusion Stroke Imaging

Peerlings, D (Utrecht University, 2024-08-27)

This thesis focuses on harmonizing and optimizing CT perfusion (CTP) imaging for stroke. CTP imaging can help select patients with ischemic stroke for thrombectomy. However, due to a lack of consensus on the CTP acquisition ...
Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data

Lau, Cedric; Mohmaed Ali, Ma Ida; Lin, Lishi; van Balen, Dorieke E M; Jacobs, Bart A W; Nuijen, Bastiaan; Smeenk, Robert M; Steeghs, Neeltje; Huitema, Alwin D R (Springer-Verlag, 2024-07)

PURPOSE: The number of patients with bariatric surgery who receive oral anticancer drugs is rising. Bariatric surgery may affect the absorption of oral anticancer drugs. Strikingly, no specific drug dosing recommendations ...
Comparative Performance Analysis of Idylla and Archer in the Detection of Gene Fusions in Spitzoid Melanocytic Tumors

Ebbelaar, Chiel F; van Dijk, Marijke; Breimer, Gerben E; Meijers, Ruud W J; Klein, Laura B C; Petronilia, Maryleen M; de Leng, Wendy W J; Blokx, Willeke A M; Jansen, Anne M L; MOLecular Evaluation of Melanocytic Ambiguous Tumors (MOLEMAT) investigators (Elsevier, 2024-08)

Melanocytic neoplasms with spitzoid histomorphology are often difficult to classify without identifying genetic drivers such as kinase fusions. Traditional diagnostic methods, such as immunohistochemistry, can yield ...
Comprehensive Characterization of Intraductal Oncocytic Papillary Neoplasm of the Pancreas: a systematic and critical review

Paolino, Gaetano; Basturk, Olca; Esposito, Irene; Hong, Seung-Mo; Brosens, Lodewijk A; Tarcan, Zeynep; Wood, Laura D; Gkountakos, Anastasios; Omori, Yuko; Mattiolo, Paola; Ciulla, Calogero; Marchegiani, Giovanni; Pea, Antonio; Bevere, Michele; De Robertis, Riccardo; D'Onofrio, Mirko; Salvia, Roberto; Cheng, Liang; Furukawa, Toru; Scarpa, Aldo; Adsay, Volkan; Luchini, Claudio (Elsevier, 2024-09)

Intraductal oncocytic papillary neoplasm (IOPN) of the pancreas is a recently recognized pancreatic tumor. Here, we aimed to determine its most essential features with the systematic review tool. PubMed, Scopus, and Embase ...
Myopia progression in children during home confinement in the COVID-19 pandemic: A systematic review and meta-analysis

Laan, Daisy; Tan, Emily T C; Huis In Het Veld, Paulien I; Jellema, Hinke Marijke; Jenniskens, Kevin (2024-03)

PURPOSE: Myopia is a growing pandemic, especially in children, who risk low vision later in life. Home confinement during the COVID-19 pandemic may have increased myopia progression through increased screentime, decreased ...
A functional polymorphism in UGT1A1 related to hyperbilirubinemia is associated with a decreased risk for Crohn's disease

de Vries, Hilbert S.; te Morsche, Rene H.M.; Jenniskens, Kevin; Peters, Wilbert H.M.; de Jong, Dirk J. (Elsevier, 2012-06)

Background: An imbalance between the production of reactive oxygen species (ROS) and their capturing by antioxidants results in oxidative stress, this may play an important role in the pathogenesis of inflammatory bowel ...
A Network Meta-Analysis of Clinical Management Strategies for Treatment-Resistant Hypertension: Making Optimal Use of the Evidence

Makai, Peter; IntHout, Joanna; Deinum, Jaap; Jenniskens, Kevin; Wilt, Gert Jan van der (Springer New York, 2017-08)

BACKGROUND: With the addition of surgical interventions to current medicinal treatments, it is increasingly challenging for clinicians to rationally choose among the various options for treating patients with apparent ...
Extracellular vesicles from seminal plasma interact with T cells in vitro and drive their differentiation into regulatory T-cells

Zhang, Xiaogang; Greve, Patrick F; Minh, Thi Tran Ngoc; Wubbolts, Richard; Demir, Ayşe Y; Zaal, Esther A; Berkers, Celia R; Boes, Marianne; Stoorvogel, Willem (John Wiley & Sons Inc., 2024-07-16)

Seminal plasma induces immune tolerance towards paternal allogenic antigens within the female reproductive tract and during foetal development. Recent evidence suggests a role for extracellular vesicles in seminal plasma ...
Did aetiology matter in illness duration and complications in patients presenting in primary care with acute respiratory tract infections early in the COVID-19 pandemic: An observational study in nine countries

Venekamp, Roderick P; Eijkemans, Marinus J C; Zuithoff, Nicolaas P A; Böhmer, Femke; Chlabicz, Slawomir; Colliers, Annelies; García-Sangenís, Ana; Malania, Lile; Pauer, Jozsef; Tomacinschii, Angela; Verheij, Theo J; Goossens, Herman; Vellinga, Akke; Butler, Christopher C; van der Velden, Alike W (Informa Healthcare, 2024-07-12)

Background: Despite considerable research into COVID-19 sequelae, little is known about differences in illness duration and complications in patients presenting in primary care with symptoms of acute respiratory tract ...
Ablation of Small Liver Metastases Presenting as Foci of Diffusion Restriction on MRI-Results from the Prospective Minimally Invasive Thermal Ablation (MITA) Study

Wijnen, Niek; Bruijnen, Rutger C G; Thelissen, Annelou A B; de Jong, Hugo W A M; van Leeuwaarde, Rachel S; Hagendoorn, Jeroen; Bol, Guus M; Smits, Maarten L J (Multidisciplinary Digital Publishing Institute (MDPI), 2024-07-01)

PURPOSE: Liver metastases presenting as small hyperintense foci on diffusion-weighted imaging (DWI) pose a therapeutic challenge. Ablation is generally not possible since these lesions are often occult on ultrasound and ...
Age-specific SARS-CoV-2 transmission differed from human rhinovirus in households during the early COVID-19 pandemic

Boom, Trisja T; de Hoog, Marieke L A; Westerhof, Ilse; Jaddoe, Vincent; Heuvelman, Valerie D; Fourie, Elandri; Sluiter-Post, Judith G C; Badoux, Paul; Euser, Sjoerd; Herpers, Bjorn; Sanders, Elisabeth A M; Eggink, Dirk; Reusken, Chantal; Bont, Louis J; Wildenbeest, Joanne G; van Houten, Marlies A; Duijts, Liesbeth; Bruijning-Verhagen, Patricia C J L (W.B. Saunders Ltd, 2024-08)

Objectives: Children are generally considered main drivers of transmission for respiratory viruses, but the emergence of SARS-CoV-2 challenged this paradigm. Human rhinovirus (RV) continued to co-circulate throughout the ...
Personalized 3D printed scaffolds: The ethical aspects

van Daal, Manon; de Kanter, Anne-Floor J; Bredenoord, Annelien L; de Graeff, Nienke (Elsevier, 2023-12-25)

Personalized 3D printed scaffolds are a new generation of implants for tissue engineering and regenerative medicine purposes. Scaffolds support cell growth, providing an artificial extracellular matrix for tissue repair ...

Now showing items 6041-6060 of 40729