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UMC Repository: Recent submissions

  • Fauser, Bart C. J. M.; Ahuja, Kamal K. (Elsevier, 2020-03)
  • Griesinger, Georg; Fauser, Bart C. J. M. (Elsevier, 2020-02)
  • Kloosterman, Mariëlle; van Stipdonk, Antonius M.W.; ter Horst, Iris; Rienstra, Michiel; Van Gelder, Isabelle C.; Vos, Marc A.; Prinzen, Frits W.; Meine, Matthias; Vernooy, Kevin; Maass, Alexander H. (2020-04)
    AIMS: Echocardiographic response after cardiac resynchronization therapy (CRT) is often lesser in ischaemic cardiomyopathy (ICM) than non-ischaemic dilated cardiomyopathy (NIDCM) patients. We assessed the association of ...
  • Koster-Brouwer, Maria E.; Rijsdijk, Mienke; Van Os, Wouter K.M.; Soliman, Ivo W.; Slooter, Arjen J.C.; De Lange, Dylan W.; Van Dijk, Diederik; Bonten, Marc J.M.; Cremer, Olaf L. (Lippincott Williams and Wilkins, 2020-05)
    Objectives: Occurrence, risk factors, and impact on daily life of chronic pain after critical illness have not been systematically studied. Design: Cohort study. Setting: A tertiary ICU in The Netherlands. Patients: We ...
  • Tessadori, Federico; Rehman, Atteeq U; Giltay, Jacques C; Xia, Fan; Streff, Haley; Duran, Karen; Bakkers, Jeroen; Lalani, Seema R; van Haaften, Gijs (Nature Publishing Group, 2020-05)
    We report here a de novo missense variant in HIST1H4J resulting in a complex syndrome combining growth delay, microcephaly and intellectual disability. Trio whole exome sequencing (WES) revealed that the proband was ...
  • Bijlsma, Rhode; Wouters, Roel; Wessels, Hester; Sleijfer, Stefan; Beerepoot, Laurens; Ten Bokkel Huinink, Daan; Cruijsen, Hester; Heijns, Joan; Lolkema, Martijn P; Steeghs, Neeltje; van Voorthuizen, Theo; Vulink, Annelie; Witteveen, Els; Ausems, Margreet; Bredenoord, Annelien; May, Anne M; Voest, Emile (2020-04)
    BACKGROUND: In precision medicine, somatic and germline DNA sequencing are essential to make genome-guided treatment decisions in patients with cancer. However, it can also uncover unsolicited findings (UFs) in germline ...
  • Leeneman, Brenda; Uyl-de Groot, Carin A; Aarts, Maureen J B; van Akkooi, Alexander C J; van den Berkmortel, Franchette W P J; van den Eertwegh, Alfons J M; de Groot, Jan Willem B; Herbschleb, Karin H; van der Hoeven, Jacobus J M; Hospers, Geke A P; Kapiteijn, Ellen; Piersma, Djura; van Rijn, Rozemarijn S; Suijkerbuijk, Karijn P M; Ten Tije, Albert J; van der Veldt, Astrid A M; Vreugdenhil, Gerard; Wouters, Michel W J M; Haanen, John B A G; Franken, Margreet G (Multidisciplinary Digital Publishing Institute (MDPI), 2020-04-18)
    Immunotherapeutic and targeted drugs improved survival of patients with metastatic melanoma. There is, however, a lack of evidence regarding their healthcare costs in clinical practice. The aim of our study was to provide ...
  • Celeng, Csilla; Takx, Richard A P; Lessmann, Nikolas; Maurovich-Horvat, Pál; Leiner, Tim; Išgum, Ivana; de Jong, Pim A (Lippincott Williams and Wilkins, 2020-05)
    PURPOSE: The purpose of this study was to elucidate the impact of being unmarried on coronary computed tomography (CT) imaging biomarkers and mortality in a lung cancer screening population. MATERIALS AND METHODS: In this ...
  • Jolink, Wilmar MT; Lindenholz, Arjen; van Etten, Ellis S; van Nieuwenhuizen, Koen M; Schreuder, Floris Hbm; Kuijf, Hugo J; van Osch, Matthias Jp; Hendrikse, Jeroen; Rinkel, Gabriel Je; Wermer, Marieke JH; Klijn, Catharina JM (Nature Publishing Group, 2020-05)
    Disruption of the blood-brain barrier (BBB) might play a role in the pathophysiology of cerebral small vessel disease-related ICH. The aim of this study was to assess presence and extent of contrast agent leakage distant ...
  • Dieleman, Jan M; Myles, Paul S; Bulfone, Liliana; Younie, Sandra; van Zaane, Bas; McGiffin, David; Moodie, Marj; Gao, Lan (Oxford University Press, 2020-02)
    BACKGROUND: The aim of this study was to simulate and compare the healthcare and economic outcomes associated with routine use of intraoperative transoesophageal echocardiography (TOE) in patients undergoing cardiac surgery ...
  • van Oers, Jos A H; de Jong, Evelien; Kemperman, Hans; Girbes, Armand R J; de Lange, Dylan W (2020-01)
    BACKGROUND: New Sepsis-3 definitions facilitate early recognition of patients with sepsis. In this study we investigated whether a single initial determination of procalcitonin (PCT) or C-reactive protein (CRP) in plasma ...
  • de Savornin Lohman, Elise; de Bitter, Tessa; Verhoeven, Rob; van der Geest, Lydia; Hagendoorn, Jeroen; Mohammad, Nadia Haj; Daams, Freek; Heinz-Josef Klümpen, Klümpen; van Gulik, Thomas; Erdmann, Joris; de Boer, Marieke; Hoogwater, Frederik; Koerkamp, Bas Groot; Braat, Andries; Verheij, Joanne; Nagtegaal, Iris; van Laarhoven, Cornelis; van den Boezem, Peter; van der Post, Rachel; de Reuver, Philip (Multidisciplinary Digital Publishing Institute (MDPI), 2020-04-09)
    Gallbladder cancer (GBC) is rare in Western populations and data about treatment and outcomes are scarce. This study aims to analyze survival and identify opportunities for improvement using population-based data from a ...
  • Dutch Pancreatic Cancer Group (BioMed Central, 2020-04-16)
    BACKGROUND: Pancreatic cancer has a very poor prognosis. Best practices for the use of chemotherapy, enzyme replacement therapy, and biliary drainage have been identified but their implementation in daily clinical practice ...
  • Busslinger, Georg A; Lissendorp, Fianne; Franken, Ingrid A; van Hillegersberg, Richard; Ruurda, Jelle P; Clevers, Hans; de Maat, Michiel F G (Royal Society Publishing, 2020-04)
    The incidence of adenocarcinoma at the gastrooesophageal junction increased over the last years. Curative treatment for patients with upper gastrointestinal (UGI) malignancies, such as oesophageal and gastric tumours, is ...
  • van Geel, Robin M J M; van Brummelen, Emilie M J; Eskens, Ferry A L M; Huijberts, Sanne C F A; de Vos, Filip Y F L; Lolkema, Martijn P J K; Devriese, Lot A; Opdam, Frans L; Marchetti, Serena; Steeghs, Neeltje; Monkhorst, Kim; Thijssen, Bas; Rosing, Hilde; Huitema, Alwin D R; Beijnen, Jos H; Bernards, René; Schellens, Jan H M (Nature Publishing Group, 2020-04)
    BACKGROUND: Mutations in KRAS result in a constitutively activated MAPK pathway. In KRAS-mutant tumours existing treatment options, e.g. MEK inhibition, have limited efficacy due to resistance through feedback activation ...
  • Konstantinides, Stavros V.; Meyer, Guy; Bueno, Hector; Galié, Nazzareno; Gibbs, J. Simon R.; Ageno, Walter; Agewall, Stefan; Almeida, Ana G.; Andreotti, Felicita; Barbato, Emanuele; Baumbach, Andreas; Beygui, Farzin; Carlsen, Jørn; De Carlo, Marco; Delcroix, Marion; Subias, Pilar Escribano; Gaine, Sean; Goldhaber, Samuel Z.; Gopalan, Deepa; Habib, Gilbert; Jenkins, David; Kjellström, Barbro; Lainscak, Mitja; Lee, Geraldine; Le Gal, Grégoire; Messas, Emmanuel; Morais, Joao; Piepoli, Massimo Francesco; Price, Susanna; Salvi, Aldo; Sanchez, Olivier; Stortecky, Stefan; Thielmann, Matthias; Noordegraaf, Anton Vonk; Becattini, Cecilia; Bueno, Héctor; Geersing, Geert Jan; Harjola, Veli Pekka; Huisman, Menno V.; Humbert, Marc; Jennings, Catriona Sian; Jiménez, David; Kucher, Nils; Lang, Irene Marthe; Lankeit, Mareike; Lorusso, Roberto; Mazzolai, Lucia; Meneveau, Nicolas; Áinle, Fionnuala Ní; Prandoni, Paolo; Pruszczyk, Piotr; Righini, Marc; Torbicki, Adam; Van Belle, Eric; Zamorano, José Luis; Windecker, Stephan; Aboyans, Victor; Baigent, Colin; Collet, Jean Philippe; Dean, Veronica; Delgado, Victoria; Fitzsimons, Donna; Gale, Chris P.; Grobbee, Diederick E.; Hindricks, Gerhard; Iung, Bernard; Jüni, Peter; Katus, Hugo A.; Landmesser, Ulf; Leclercq, Christophe; Lettino, Maddalena; Lewis, Basil S.; Merkely, Bela; Mueller, Christian; Petersen, Steffen E.; Petronio, Anna Sonia; Richter, Dimitrios J.; Roffi, Marco; Shlyakhto, Evgeny; Simpson, Iain A.; Sousa-Uva, Miguel; Touyz, Rhian M.; Hammoudi, Naima; Hayrapetyan, Hamlet; Mascherbauer, Julia; Ibrahimov, Firdovsi; Polonetsky, Oleg; Lancellotti, Patrizio; Tokmakova, Mariya; Skoric, Bosko; Michaloliakos, Ioannis; Hutyra, Martin; Mellemkjaer, Søren; Mansour, Mostafa; Reinmets, Julia; Jääskeläinen, Pertti; Angoulvant, Denis; Bauersachs, Johann; Giannakoulas, George; Zima, Endre; Vizza, Carmine Dario; Sugraliyev, Akhmetzhan; Bytyçi, Ibadete; Maca, Aija; Ereminiene, Egle; Huijnen, Steve; Xuereb, Robert; Diaconu, Nadejda; Bulatovic, Nebojsa; Asfalou, Ilyasse; Bosevski, Marijan; Halvorsen, Sigrun; Sobkowicz, Bozena; Ferreira, Daniel; Petris, Antoniu Octavian; Moiseeva, Olga; Zavatta, Marco; Obradovic, Slobodan; Šimkova, Iveta; Radsel, Peter; Ibanez, Borja; Wikström, Gerhard; Aujesky, Drahomir; Kaymaz, Cihangir; Parkhomenko, Alexander; Pepke-Zaba, Joanna (Oxford University Press, 2020-01-21)
    Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing the best management strategies for an individual patient with a given condition. Guidelines and their ...
  • Young, Peter W; Zielinski-Gutierrez, Emily; Wamicwe, Joyce; Mukui, Irene; Kim, Andrea A; Waruru, Anthony; Zeh, Clement; Kretzschmar, Mirjam E; De Cock, Kevin M (Lippincott Williams and Wilkins, 2020-03-15)
    Objective:To compare alternative methods of adjusting self-reported knowledge of HIV-positive status and antiretroviral (ARV) therapy use based on undetectable viral load (UVL) and ARV detection in blood.Design:Post hoc ...
  • Konradsson, M; van Berge Henegouwen, M I; Bruns, C; Chaudry, M A; Cheong, E; Cuesta, M A; Darling, G E; Gisbertz, S S; Griffin, S M; Gutschow, C A; van Hillegersberg, R; Hofstetter, W; Hölscher, A H; Kitagawa, Y; van Lanschot, J J B; Lindblad, M; Ferri, L E; Low, D E; Luyer, M D P; Ndegwa, N; Mercer, S; Moorthy, K; Morse, C R; Nafteux, P; Nieuwehuijzen, G A P; Pattyn, P; Rosman, C; Ruurda, J P; Räsänen, J; Schneider, P M; Schröder, W; Sgromo, B; Van Veer, H; Wijnhoven, B P L; Nilsson, M (Wiley-Blackwell, 2020-04-15)
    Delayed gastric conduit emptying (DGCE) after esophagectomy for cancer is associated with adverse outcomes and troubling symptoms. Widely accepted diagnostic criteria and a symptom grading tool for DGCE are missing. This ...
  • Kroeze, S G C; Fritz, C; Kaul, D; Blanck, O; Kahl, K; Roeder, F; Siva, S; Verhoeff, J J C; Grosu, A L; Schymalla, M M; Glatzer, M; Szuecs, M; Geier, M; Skazikis, G; Sackerer, I; Lohaus, F; Eckert, F; Guckenberger, M (Oxford University Press, 2019-04)
  • Boekhoff, M. R.; Defize, I. L.; Borggreve, A. S.; Takahashi, N.; van Lier, A. L.H.M.W.; Ruurda, J. P.; van Hillegersberg, R.; Lagendijk, J. J.W.; Mook, S.; Meijer, G. J. (Elsevier Ireland Ltd, 2020-06-01)
    Purpose: This study aimed to quantify the coverage probability for esophageal cancer radiotherapy as a function of a preset margin for online MR-guided and (CB)CT-guided radiotherapy. Methods: Thirty esophageal cancer ...