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Now showing items 29501-29520 of 40729

Reward anticipation in ventral striatum and individual sensitivity to reward: A pilot study of a child-friendly fMRI task

Van Hulst, Branko M.; de Zeeuw, Patrick; Lupas, Kellina; Bos, Dienke J.; Neggers, Sebastiaan F W; Durston, Sarah (Public Library of Science, 2015-11-01)

Reward processing has been implicated in developmental disorders. However, the classic task to probe reward anticipation, the monetary incentive delay task, has an abstract coding of reward and no storyline and may therefore ...
Resectie van levermetastasen bij borstkanker: Stand van zaken

Ruiz, Aldrick; Wicherts, Dennis; Adam, René; Siesling, Sabine; Linn, Sabine; Van Hillegersberg, Richard (Bohn Stafleu van Loghum, 2015)

Liver metastases have the poorest prognosis of all types of breast cancer metastases, with a 5year survival rate of 0 to 12%. In comparison, the 5year overall survival rate of patients with colorectal liver metastases ...
European neonatal intensive care nursing research priorities: an e-Delphi study

Wielenga, Joke M; Tume, Lyvonne N; Latour, Jos M; van den Hoogen, Agnes (BMJ Publishing Group, 2015-01)

OBJECTIVE: This study aimed to identify and prioritise neonatal intensive care nursing research topics across Europe using an e-Delphi technique. DESIGN: An e-Delphi technique with three questionnaire rounds was performed. ...
A roadmap for paediatric and neonatal critical care nursing science in Europe: engage, action and impact

Tume, Lyvonne N; Ista, Erwin; van den Hoogen, Agnes; Wielenga, Joke; Latour, Jos M (Wiley-Blackwell, 2015-09)
Compliance in oxygen saturation targeting in preterm infants: a systematic review

van Zanten, Henriëtte A; Tan, Ratna N G B; van den Hoogen, Agnes; Lopriore, Enrico; te Pas, Arjan B (Springer-Verlag, 2015-12)

UNLABELLED: During oxygen therapy in preterm infants, targeting oxygen saturation is important for avoiding hypoxaemia and hyperoxaemia, but this can be very difficult and challenging for neonatal nurses. We systematically ...
RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

Best, Myron G.; Sol, Nik; Kooi, Irsan; Tannous, Jihane; Westerman, Bart A.; Rustenburg, François; Schellen, Pepijn; Verschueren, Heleen; Post, Edward; Koster, Jan; Ylstra, Bauke; Ameziane, Najim; Dorsman, Josephine; Smit, Egbert F.; Verheul, Henk M.; Noske, David P.; Reijneveld, Jaap C.; Nilsson, R. Jonas A; Tannous, Bakhos A.; Wesseling, Pieter; Wurdinger, Thomas (Cell Press, 2015-11-09)

Tumor-educated blood platelets (TEPs) are implicated as central players in the systemic and local responses to tumor growth, thereby altering their RNA profile. We determined the diagnostic potential of TEPs by mRNA ...
Increase in Both CD14-Positive and CD15-Positive Myeloid-Derived Suppressor Cell Subpopulations in the Blood of Patients with Glioma but Predominance of CD15-Positive Myeloid-Derived Suppressor Cells in Glioma Tissue

Gielen, Paul R.; Schulte, Barbara M.; Kers-Rebel, Esther D.; Verrijp, Kiek; Petersen-Baltussen, Harriëtte M J M; Ter Laan, Mark; Wesseling, Pieter; Adema, Gosse J. (Lippincott Williams & Wilkins, 2015-05-04)

Myeloid-derived suppressor cells (MDSCs), defined as CD33-positive major histocompatibility complex class II-negative cells, are increased in a variety of human tumors and are associated with immunosuppression. Myeloid-derived ...
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer

Barault, L.; Amatu, A.; Bleeker, F. E.; Moutinho, C.; Falcomatà, C.; Fiano, V.; Cassingena, A.; Siravegna, G.; Milione, M.; Cassoni, P.; de Braud, F.; Rudà, R.; Soffietti, R.; Venesio, T.; Bardelli, A.; Wesseling, P.; de Witt Hamer, P.; Pietrantonio, F.; Siena, S.; Esteller, M.; Sartore-Bianchi, A.; di Nicolantonio, Federica (Oxford University Press, 2015-09-01)

Background: O6-methyl-guanine-methyl-transferase (MGMT) silencing by promoter methylation may identify cancer patients responding to the alkylating agents dacarbazine or temozolomide. Patients and methods: We evaluated the ...
Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment

van Thuijl, Hinke F.; Mazor, Tali; Johnson, Brett E.; Fouse, Shaun D.; Aihara, Koki; Hong, Chibo; Malmström, Annika; Hallbeck, Martin; Heimans, Jan J.; Kloezeman, Jenneke J.; Stenmark-Askmalm, Marie; Lamfers, Martine L M; Saito, Nobuhito; Aburatani, Hiroyuki; Mukasa, Akitake; Berger, Mitchell S.; Söderkvist, Peter; Taylor, Barry S.; Molinaro, Annette M.; Wesseling, Pieter; Reijneveld, Jaap C.; Chang, Susan M.; Ylstra, Bauke; Costello, Joseph F. (Springer, 2015-04-01)

Temozolomide (TMZ) increases the overall survival of patients with glioblastoma (GBM), but its role in the clinical management of diffuse low-grade gliomas (LGG) is still being defined. DNA hypermethylation of the ...
IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II–III diffuse gliomas

Olar, Adriana; Wani, Khalida M.; Alfaro-Munoz, Kristin D.; Heathcock, Lindsey E.; van Thuijl, Hinke F.; Gilbert, Mark R.; Armstrong, Terri S.; Sulman, Erik P.; Cahill, Daniel P.; Vera-Bolanos, Elizabeth; Yuan, Ying; Reijneveld, Jaap C.; Ylstra, Bauke; Wesseling, Pieter; Aldape, Kenneth D. (Springer, 2015-04-01)

Diffuse gliomas are up till now graded based upon morphology. Recent findings indicate that isocitrate dehydrogenase (IDH) mutation status defines biologically distinct groups of tumors. The role of tumor grade and mitotic ...
Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein

Navis, Anna C.; van Lith, Sanne A M; van Duijnhoven, Sander M J; de Pooter, Maaike; Yetkin-Arik, Bahar; Wesseling, Pieter; Hendriks, Wiljan J A J; Venselaar, Hanka; Timmer, Marco; van Cleef, Patricia; van Bergen en Henegouwen, Paul; Best, Myron G.; Wurdinger, Thomas D.; Tops, Bastiaan B J; Leenders, William P J (Springer, 2015-07)

MET has gained interest as a therapeutic target for a number of malignancies because of its involvement in tumorigenesis, invasion and metastasis. At present, a number of inhibitors, both antibodies against MET or its ...
Mutations in G Protein Encoding Genes and Chromosomal Alterations in Primary Leptomeningeal Melanocytic Neoplasms

Küsters-Vandevelde, Heidi V N; van Engen- van Grunsven, Ilse A C H; Coupland, Sarah E.; Lake, Sarah L.; Rijntjes, Jos; Pfundt, Rolph; Küsters, Benno; Wesseling, Pieter; Blokx, Willeke A M; Groenen, Patricia J T A (Springer Netherlands, 2015-04-28)

Limited data is available on the genetic features of primary leptomeningeal melanocytic neoplasms (LMNs). Similarities with uveal melanoma were recently suggested as both entities harbor oncogenic mutations in GNAQ and ...
IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO

Reuss, David E.; Mamatjan, Yasin; Schrimpf, Daniel; Capper, David; Hovestadt, Volker; Kratz, Annekathrin; Sahm, Felix; Koelsche, Christian; Korshunov, Andrey; Olar, Adriana; Hartmann, Christian; Reijneveld, Jaap C.; Wesseling, Pieter; Unterberg, Andreas; Platten, Michael; Wick, Wolfgang; Herold-Mende, Christel; Aldape, Kenneth; von Deimling, Andreas (Springer, 2015-05-12)

The WHO 2007 classification of tumors of the CNS distinguishes between diffuse astrocytoma WHO grade II (A IIWHO2007) and anaplastic astrocytoma WHO grade III (AA IIIWHO2007). Patients with A IIWHO2007 are significantly ...
Pregnancy outcome after fetal reduction in women with a dichorionic twin pregnancy

van de Mheen, L; Everwijn, S M P; Knapen, M F C M; Haak, M C; Engels, M A J; Manten, G T R; Zondervan, H A; Wirjosoekarto, S A M; van Vugt, J M G; Erwich, J J H M; Bilardo, C M; van Pampus, M G; de Groot, C J M; Mol, B W J; Pajkrt, E (Oxford University Press, 2015-08)

STUDY QUESTION: What are the pregnancy outcomes for women with a twin pregnancy that is reduced to a singleton pregnancy? SUMMARY ANSWER: Fetal reduction of a twin pregnancy significantly improves gestational age at birth ...
Intrauterine insemination or intracervical insemination with cryopreserved donor sperm in the natural cycle: A cohort study

Kop, P. A L; Van Wely, M.; Mol, B. W.; De Melker, A. A.; Janssens, P. M W; Arends, B.; Curfs, M. H J M; Kortman, M.; Nap, A.; Rijnders, E.; Roovers, J. P W R; Ruis, H.; Simons, A. H M; Repping, S.; Van Der Veen, F.; Mochtar, M. H. (Oxford University Press, 2015)

studyquestion: Does intrauterine insemination in the natural cycle lead to better pregnancy rates than intracervical insemination (ICI) in the natural cycle in women undergoing artificial insemination with cryopreserved ...
A 43-year-old female with multifocal cerebral lesions

Nieuwenhuis, Marieke B B; Van Der Salm, Sandra M A; Verhoeff, Joost J C; Van Der Kooi, Anneke J.; Slavujecvic-Letic, Ivana; Pals, Steven T.; Vos, Josephine M I (Wiley-Blackwell, 2015-05-01)
Bevacizumab in combination with radiotherapy and temozolomide for patients with newly diagnosed glioblastomamultiforme

Van Linde, Myra E.; Verhoeff, Joost J C; Richel, Dirk J.; Van Furth, Wouter R.; Reijneveld, Jaap C.; Verheul, Henk M W; Stalpers, Lukas J A (AlphaMed Press, 2015-01-12)

Background. Patients with a newly diagnosed glioblastoma multiforme (GBM) have a high risk of recurrent disease with a dismal outcome despite intensive treatment of sequential surgery and chemoradiotherapy with temozolomide ...
The minimum spanning tree: An unbiased method for brain network analysis

Tewarie, P.; van Dellen, E.; Hillebrand, A.; Stam, C. J. (Academic Press Inc., 2015-01-01)

The brain is increasingly studied with graph theoretical approaches, which can be used to characterize network topology. However, studies on brain networks have reported contradictory findings, and do not easily converge ...
Learning of anticipatory responses in single neurons of the human medial temporal lobe

Reddy, Leila; Poncet, Marlene; Self, Matthew W.; Peters, Judith C.; Douw, Linda; Van Dellen, Edwin; Claus, Steven; Reijneveld, Jaap C.; Baayen, Johannes C.; Roelfsema, Pieter R. (Nature Publishing Group, 2015-10-09)

Neuronal processes underlying the formation of new associations in the human brain are not yet well understood. Here human participants, implanted with depth electrodes in the brain, learned arbitrary associations between ...
Effects of blocking D2/D3 receptors on mismatch negativity and P3a amplitude of initially antipsychotic naïve, first episode schizophrenia patients

Düring, Signe; Glenthøj, Birte Yding; Oranje, Bob (Oxford University Press, 2015-05-19)

Background: Reduced mismatch negativity and P3a amplitude have been suggested to be among the core deficits in schizophrenia since the late 1970s. Blockade of dopamine D2 receptors play an important role in the treatment ...

Now showing items 29501-29520 of 40729