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UMC Repository: Recent submissions

  • Does a bounding exercise program prevent hamstring injuries in adult male soccer players? – A cluster-RCT 
    van de Hoef, Peter Alexander; Brink, Michel S.; Huisstede, Bionka M.A.; van Smeden, Maarten; de Vries, Niels; Goedhart, Edwin A.; Gouttebarge, Vincent; Backx, Frank J.G. (Blackwell Munksgaard, 2019-04-01)
    Background: Although the Nordic Hamstring Exercise (NHE) prevents hamstring injury in soccer players effectively, the annual incidence of these injuries still increases. This may be because of poor long-term compliance ...
  • Histone modifications underlie monocyte dysregulation in patients with systemic sclerosis, underlining the treatment potential of epigenetic targeting 
    Van Der Kroef, Maarten; Castellucci, Monica; Mokry, Michal; Cossu, Marta; Garonzi, Marianna; Bossini-Castillo, Lara M.; Chouri, Eleni; Wichers, Catharina G.K.; Beretta, Lorenzo; Trombetta, Elena; Silva-Cardoso, Sandra; Vazirpanah, Nadia; Carvalheiro, Tiago; Angiolilli, Chiara; Bekker, Cornelis P.J.; Affandi, Alsya J.; Reedquist, Kris A.; Bonte-Mineur, Femke; Zirkzee, Els J.M.; Bazzoni, Flavia; Radstake, Timothy R.D.J.; Rossato, Marzia (Elsevier, 2019-04-01)
    Background and objective Systemic sclerosis (SSc) is a severe autoimmune disease, in which the pathogenesis is dependent on both genetic and epigenetic factors. Altered gene expression in SSc monocytes, particularly of ...
  • The Long Non-coding RNA NRIR Drives IFN-Response in Monocytes: Implication for Systemic Sclerosis 
    Mariotti, Barbara; Servaas, Nila Hendrika; Rossato, Marzia; Tamassia, Nicola; Cassatella, Marco A.; Cossu, Marta; Beretta, Lorenzo; van der Kroef, Maarten; Radstake, Timothy R.D.J.; Bazzoni, Flavia (Frontiers Media S. A., 2019-01-01)
    TLR4 activation initiates a signaling cascade leading to the production of type I IFNs and of the downstream IFN-stimulated genes (ISGs). Recently, a number of IFN-induced long non-coding RNAs (lncRNAs) that feed-back ...
  • Associations of the metabolic syndrome and its components with cognitive impairment in older adults 
    Feinkohl, Insa; Janke, Jürgen; Hadzidiakos, Daniel; Slooter, Arjen; Winterer, Georg; Spies, Claudia; Pischon, Tobias (BioMed Central, 2019-03-07)
    Background: The metabolic syndrome (MetS) is an established cardiovascular risk factor. Here, we investigated its role in cognitive impairment. Methods: Baseline data from 202 participants (aged 65 to 87 years) of the ...
  • Corrigendum: Mlplasmids: A user-friendly tool to predict plasmid-and chromosome-derived sequences for single species, (Microbial Genomics), (2018), 4, 10.1099/mgen.0.000224 
    Arredondo-Alonso, Sergio; Rogers, Malbert R.C.; Braat, Johanna C.; Verschuuren, Tess D.; Top, Janetta; Corander, Jukka; Willems, Rob J.L.; Schürch, Anita C. (Microbiology Society, 2019-01-01)
    There was an error in the Funding information section in the published article. The Funding information section should include the following sentence: ‘This study was supported by the Joint Programming Initiative in ...
  • Long-term effects of radioiodine treatment on salivary gland function in adult survivors of pediatric differentiated thyroid carcinoma 
    Dutch Pediatric Thyroid Cancer Study Consortium (Society of Nuclear Medicine Inc., 2019-02-01)
    Pediatric differentiated thyroid cancer (DTC) is a rare disease. Initial treatment of DTC consists of a total or near-total thyroidectomy and131I therapy. Previous studies on adults showed that131I treatment may reduce ...
  • Hydrocracking of vacuum gas oil over NiMo/zeolite-Al2O3: Influence of zeolite properties 
    Dik, P. P.; Danilova, I. G.; Golubev, I. S.; Kazakov, M. O.; Nadeina, K. A.; Budukva, S. V.; Pereyma, V. Yu.; Klimov, O. V.; Prosvirin, I. P.; Gerasimov, E. Yu.; Bok, T. O.; Dobryakova, I. V.; Knyazeva, E. E.; Ivanova, I. I.; Noskov, A. S. (Elsevier, 2019-02-01)
    Hydrocracking of vacuum gas oil has been studied over NiMo/zeolite-Al2O3 catalysts. Three different zeolites have been used for catalysts preparation: zeolites Beta (BEA) and Y (FAU) having small crystal size and zeolite ...
  • Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice 
    Aden, Konrad; Bartsch, Kareen; Dahl, Joseph; Reijns, Martin A.M.; Esser, Daniela; Sheibani-Tezerji, Raheleh; Sinha, Anupam; Wottawa, Felix; Ito, Go; Mishra, Neha; Knittler, Katharina; Burkholder, Adam; Welz, Lina; van Es, Johan; Tran, Florian; Lipinski, Simone; Kakavand, Nassim; Boeger, Christine; Lucius, Ralph; von Schoenfels, Witigo; Schafmayer, Clemens; Lenk, Lennart; Chalaris, Athena; Clevers, Hans; Röcken, Christoph; Kaleta, Christoph; Rose-John, Stefan; Schreiber, Stefan; Kunkel, Thomas; Rabe, Björn; Rosenstiel, Philip (W.B. Saunders, 2019-01-01)
    Background & Aims: RNase H2 is a holoenzyme, composed of 3 subunits (ribonuclease H2 subunits A, B, and C), that cleaves RNA:DNA hybrids and removes mis-incorporated ribonucleotides from genomic DNA through ribonucleotide ...
  • Measurement properties of instruments to assess pain in children and adolescents with cancer: A systematic review protocol 
    Loeffen, Erik A.H.; Stinson, Jennifer N.; Birnie, Kathryn A.; Van Dijk, Monique; Kulkarni, Ketan; Rijsdijk, Mienke; Font-Gonzalez, Anna; Dupuis, L. Lee; Van Dalen, Elvira C.; Mulder, Renée L.; Campbell, Fiona; Tissing, Wim J.E.; Van De Wetering, Marianne D.; Gibson, Faith (BioMed Central, 2019-01-28)
    Background: Pain in children and adolescents with cancer has been identified as an area where many healthcare professionals seek guidance. This protocol details a systematic review whose aim is to explore current knowledge ...
  • Pain management in acute otitis media: A qualitative study of parents' views and expectations 
    Van Uum, Rick T.; Venekamp, Roderick P.; Schilder, Anne G.M.; Damoiseaux, Roger A.M.J.; Anthierens, Sibyl (BioMed Central, 2019-01-23)
    Background: For unclarified reasons, parents tend to be cautious about administering analgesics to their children, potentially leading to suboptimal management of AOM symptoms. We aim to understand parents' views and ...
  • Rituximab in patients with primary CNS lymphoma (HOVON 105/ALLG NHL 24): a randomised, open-label, phase 3 intergroup study 
    Bromberg, Jacoline E.C.; Issa, Samar; Bakunina, Katerina; Minnema, Monique C.; Seute, Tatjana; Durian, Marc; Cull, Gavin; Schouten, Harry C.; Stevens, Wendy B.C.; Zijlstra, Josee M.; Baars, Joke W.; Nijland, Marcel; Mason, Kylie D.; Beeker, Aart; van den Bent, Martin J.; Beijert, Max; Gonzales, Michael; de Jong, Daphne; Doorduijn, Jeanette K. (Elsevier Limited, 2019-02-01)
    Background: The prognosis for primary CNS lymphoma has improved with the use of high-dose methotrexate-based chemotherapy, but patient outcomes remain poor. Rituximab, a chimeric monoclonal antibody that targets the CD20 ...
  • Concordance in Aneurysm Size at Time of Rupture in Familial Intracranial Aneurysms 
    Bourcier, Romain; Lindgren, Antti; Desal, Hubert; L'Allinec, Vincent; Januel, Anne Christine; Koivisto, Timo; Jääskeläinen, Juha E.; Slot, Emma M.H.; Mensing, Liselore; Zuithoff, Nicolaas P.A.; Milot, Geneviève; Algra, Ale; Rinkel, Gabriël J.E.; Ruigrok, Ynte (Lippincott Williams & Wilkins, 2019-02-01)
    Background and Purpose- Intracranial aneurysm (IA) size and location are important determinants of aneurysm rupture risk. In familial IAs there is concordance of location; however, if such concordance exists for size is ...
  • Tumor to cervical spinal cord standardized uptake ratio (SUR) improves the reproducibility of F-18-FDG-PET based tumor segmentation in head and neck squamous cell carcinoma in a multicenter setting 
    van den Bosch, Sven; Dijkema, Tim; Philippens, Marielle E P; Terhaard, Chris H J; Hoebers, Frank J P; Kaanders, Johannes H A M; Oyen, Wim J G (Elsevier Ireland Ltd, 2019-01)
    BACKGROUND: In quantitative FDG-PET data analysis, normalization of the standardized uptake value (SUV) with an internal image-derived standard improves its reproducibility. In this study, the cervical spinal cord is ...
  • Quantifying cardiac-induced brain tissue expansion using DENSE 
    Adams, Ayodeji L.; Kuijf, Hugo J.; Viergever, Max A.; Luijten, Peter R.; Zwanenburg, Jaco J.M. (John Wiley & Sons Inc., 2019-02)
    Brain tissue undergoes viscoelastic deformation and volumetric strain as it expands over the cardiac cycle due to blood volume changes within the underlying microvasculature. Volumetric strain measurements may therefore ...
  • Geriatric assessment in elderly patients with end-stage kidney disease 
    Goto, Namiko A.; Van Loon, Ismay N.; Morpey, Moira I.; Verhaar, Marianne C.; Willems, Hanna C.; Emmelot-Vonk, Mariëlle H.; Bots, Michiel L.; Boereboom, Franciscus T.J.; Hamaker, Marije E. (S. Karger AG, 2019)
    Background/Aims: Decision-making in elderly patients considering dialysis is highly complex. With the increasing number of elderly with end-stage kidney disease (ESKD), it may be important to assess geriatric impairments ...
  • Accidental falling in community-dwelling elderly with chronic kidney disease 
    Goto, Namiko A.; Hamaker, Marije E.; Willems, Hanna C.; Verhaar, Marianne C.; Emmelot-Vonk, Mariëlle H. (Springer Netherlands, 2019-01)
    Purpose: The aim of the current study was to evaluate the association between a decreased estimated glomerular filtration rate (eGFR) and accidental falling in elderly patients who visited the day clinic of the department ...
  • Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study 
    van Beers, Eduard J.; van Straaten, Stephanie; Morton, D. Holmes; Barcellini, Wilma; Eber, Stefan W.; Glader, Bertil; Yaish, Hassan M.; Chonat, Satheesh; Kwiatkowski, Janet L.; Rothman, Jennifer A.; Sharma, Mukta; Neufeld, Ellis J.; Sheth, Sujit; Despotovic, Jenny M.; Kollmar, Nina; Pospíšilová, Dagmar; Knoll, Christine M.; Kuo, Kevin; Pastore, Yves D.; Thompson, Alexis A.; Newburger, Peter E.; Ravindranath, Yaddanapudi; Wang, Winfred C.; Wlodarski, Marcin W.; Wang, Heng; Holzhauer, Susanne; Breakey, Vicky R.; Verhovsek, Madeleine; Kunz, Joachim; McNaull, Melissa A.; Rose, Melissa J.; Bradeen, Heather A.; Addonizio, Kathryn; Li, Anran; Al-Sayegh, Hasan; London, Wendy B.; Grace, Rachael F. (Ferrata Storti Foundation, 2019-02-01)
  • Glycogen storage disease type IV: A rare cause for neuromuscular disorders or often missed? 
    Schene, Imre F.; Korenke, Christoph G.; Huidekoper, Hidde H.; van der Pol, Ludo; Dooijes, Dennis; Breur, Johannes M.P.J.; Biskup, Saskia; Fuchs, Sabine A.; Visser, Gepke (Springer, 2019-01-01)
    Advancements in genetic testing now allow early identification of previously unresolved neuromuscular phenotypes. To illustrate this, we here present diagnoses of glycogen storage disease IV (GSD IV) in two patients with ...
  • HIV, immune activation and cardiovascular disease in the sub-Saharan African context 
    Vos, A.G. (Utrecht University, 2019-06-20)
    HIV is a public health concern with currently 37 million people living with HIV (PLHIV) globally. Around 70% of PLHIV reside in sub-Saharan Africa (SSA). Antiretroviral therapy (ART) has turned HIV from a deadly disease ...
  • Masticatory ability improves after maxillary implant overdenture treatment: A randomized controlled trial with 1-year follow-up 
    Boven, Geessien C.; Speksnijder, Caroline M.; Meijer, Henny J. A.; Vissink, Arjan; Raghoebar, Gerry M. (Wiley-Blackwell, 2019-04)
    Background The effect of maxillary implant overdentures on masticatory ability in edentulous patients with complaints regarding their conventional maxillary dentures is unknown. Purpose To assess the change in objective ...