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UMC Repository: Recent submissions

  • Neurobehavioural mechanisms of threat generalization moderate the link between childhood maltreatment and psychopathology in emerging adulthood 
    Lange, Iris; Goossens, Liesbet; Bakker, Jindra; Michielse, Stijn; van Winkel, Ruud; Lissek, Shmuel; Leibold, Nicole; Marcelis, Machteld; Wichers, Marieke; van Os, Jim; van Amelsvoort, Therese; Schruers, Koen (Canadian Medical Association, 2019-05)
    Background: Childhood maltreatment is a transdiagnostic risk factor for later psychopathology and has been associated with altered brain circuitry involved in the processing of threat and safety. Examining threat generalization ...
  • Vitamin D intake, serum 25-hydroxy vitamin D and pulmonary function in paediatric patients with cystic fibrosis: A longitudinal approach 
    Timmers, Nyanza K.L.M.; Stellato, Rebecca K.; Van Der Ent, Cornelis K.; Houwen, Roderick H.J.; Woestenenk, Janna W. (Cambridge University Press, 2019-01-28)
    Pancreatic-insufficient children with cystic fibrosis (CF) receive age-group-specific vitamin D supplementation according to international CF nutritional guidelines. The potential advantageous immunomodulatory effect of ...
  • Renaming schizophrenia: 5 × 5 
    Guloksuz, Sinan; van Os, Jim (Cambridge University Press, 2019-06)
    There had been a long way to go before we felt comfortable about even discussing the issues revolving around the concept of 'schizophrenia', let alone reckoning on mere semantic revision. In this editorial, we aim to extend ...
  • Concordance of child self-reported psychotic experiences with interview- and observer-based psychotic experiences 
    Gundersen, Steffie V.; Goodman, Robert; Clemmensen, Lars; Rimvall, Martin K.; Munkholm, Anja; Rask, Charlotte Ulrikka; Skovgaard, Anne Mette; Van Os, Jim; Jeppesen, Pia (Wiley-Blackwell, 2019-06)
    Aim: Valid instruments for the early identification of psychotic experiences (PE) and symptoms in youths are urgently needed for large-scale preventive interventions. A new section of The-Development-and-Well-Being Assessment ...
  • Simultaneous Micropatterning of Fibrous Meshes and Bioinks for the Fabrication of Living Tissue Constructs 
    de Ruijter, Mylène; Ribeiro, Alexandre; Dokter, Inge; Castilho, Miguel; Malda, Jos (John Wiley & Sons Inc., 2019-04)
    Fabrication of biomimetic tissues holds much promise for the regeneration of cells or organs that are lost or damaged due to injury or disease. To enable the generation of complex, multicellular tissues on demand, the ...
  • Is BDNF-Val66Met polymorphism associated with psychotic experiences and psychotic disorder outcome?: Evidence from a 6 years prospective population-based cohort study 
    Kirli, Umut; Binbay, Tolga; Drukker, Marjan; Elbi, Hayriye; Kayahan, Bulent; Gokcelli, Duygu Keskin; Ozkinay, Ferda; Onay, Huseyin; Alptekin, Koksal; van Os, Jim (Wiley-Liss Inc., 2019-03)
    There is little research on genetic risk for the extended psychosis phenotype ranging from psychotic experiences (PEs) to psychotic disorders (PDs). In this general population-based prospective cohort study, the longitudinal ...
  • Psychotic experiences are associated with health anxiety and functional somatic symptoms in preadolescence 
    Rimvall, Martin K.; Jespersen, Cecilia Pihl; Clemmensen, Lars; Munkholm, Anja; Skovgaard, Anne Mette; Verhulst, Frank; van Os, Jim; Rask, Charlotte Ulrikka; Jeppesen, Pia (Wiley-Blackwell, 2019-05)
    Background: Health anxiety (HA) is an increasing public health problem related to increased health service costs, and associated with functional somatic symptoms (FSS) and considerable personal suffering. Abnormal bodily ...
  • Uniformity in measuring adherence to reporting guidelines: The example of TRIPOD for assessing completeness of reporting of prediction model studies 
    Heus, Pauline; Damen, Johanna A.A.G.; Pajouheshnia, Romin; Scholten, Rob J.P.M.; Reitsma, Johannes B.; Collins, Gary S.; Altman, Douglas G.; Moons, Karel G.M.; Hooft, Lotty (BMJ Publishing Group, 2019-04-24)
    To promote uniformity in measuring adherence to the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) statement, a reporting guideline for diagnostic and prognostic ...
  • The effect of computerized decision support systems on cardiovascular risk factors: A systematic review and meta-analysis 
    Groenhof, T. Katrien J.; Asselbergs, Folkert W.; Groenwold, Rolf H. H.; Grobbee, Diederick E.; Visseren, Frank L. J.; Bots, Michiel L.; Asselbergs, Folkert W.; Nathoe, H. M.; de Borst, G. J.; Bots, Michiel L.; Geerlings, M. I.; Emmelot, M. H.; de Jong, P. A.; Leiner, T.; Lely, A. T.; van der Kaaij, N. P.; Kappelle, L. J.; Ruigrok, Y. M.; Verhaar, M. C.; Visseren, Frank L. J.; Westerink, J. (BioMed Central, 2019-06-10)
    BACKGROUND: Cardiovascular risk management (CVRM) is notoriously difficult because of multi-morbidity and the different phenotypes and severities of cardiovascular disease. Computerized decision support systems (CDSS) ...
  • Discovery of pyridoxal reductase activity as part of human vitamin B6 metabolism 
    Ramos, Rúben J; Albersen, Monique; Vringer, Esmee; Bosma, Marjolein; Zwakenberg, Susan; Zwartkruis, Fried; Jans, Judith J M; Verhoeven-Duif, Nanda M (Elsevier, 2019-06)
    BACKGROUND: Pyridoxal 5'-phosphate (PLP) is the active form of vitamin B6. Mammals cannot synthesize vitamin B6, so they rely on dietary uptake of the different B6 forms, and via the B6 salvage pathway they interconvert ...
  • Equivalent Long-term Transplantation Outcomes for Kidneys Donated After Brain Death and Cardiac Death: Conclusions From a Nationwide Evaluation 
    Schaapherder, Alexander; Wijermars, Leonie G M; de Vries, Dorottya K; de Vries, Aiko P J; Bemelman, Frederike J; van de Wetering, Jacqueline; van Zuilen, Arjan D; Christiaans, Maarten H L; Hilbrands, Luuk H; Baas, Marije C; Nurmohamed, Azam S; Berger, Stefan P; Alwayn, Ian P; Bastiaannet, Esther; Lindeman, Jan H N (Elsevier, 2019-06-14)
    Background: Despite growing waiting lists for renal transplants, hesitations persist with regard to the use of deceased after cardiac death (DCD) renal grafts. We evaluated the outcomes of DCD donations in The Netherlands, ...
  • Understanding of and perceptions towards cardiovascular diseases and their risk factors: a qualitative study among residents of urban informal settings in Nairobi 
    Wekesah, Frederick Murunga; Kyobutungi, Catherine; Grobbee, Diederick E; Klipstein-Grobusch, Kerstin (BMJ Publishing Group, 2019-06-16)
    OBJECTIVES: The study explored the understanding of and perception towards cardiovascular disease (CVD) and risk factors, and how they influence prevention and development of the conditions, care-seeking and adhering to ...
  • Equity in maternal health outcomes in a middle-income urban setting: a cohort study 
    De Groot, Amanda; Van de Munt, Lisanne; Boateng, Daniel; Savitri, Ary I; Antwi, Edward; Bolten, Nienke; Klipstein-Grobusch, Kerstin; Uiterwaal, Cuno S P M; Browne, Joyce L (BioMed Central Ltd., 2019-06-18)
    BACKGROUND: Low socioeconomic status (SES) is associated with more adverse perinatal health outcomes, risk factors and lower access to and use of maternal health care services. However, evidence for the association between ...
  • ESMO-ESGO consensus conference recommendations on ovarian cancer: pathology and molecular biology, early and advanced stages, borderline tumours and recurrent disease 
    Colombo, N.; Sessa, C.; du Bois, A.; Ledermann, J.; McCluggage, W. G.; McNeish, I.; Morice, P.; Pignata, S.; Ray-Coquard, I.; Vergote, I.; Baert, T.; Belaroussi, I.; Dashora, A.; Olbrecht, S.; Planchamp, F.; Querleu, D.; Banerjee, S.; Blecharz, P.; Bruchim, I.; Cibula, D.; Concin, N.; Davidson, B.; Devouassoux-Shisheboran, M.; Ferrero, A.; Glasspool, R.; Gonzalez-Martin, A.; Heinzelmann-Schwarz, V.; Joly, F.; Kim, J. W.; Kridelka, F.; Lorusso, D.; Mahner, S.; Mikami, M.; Mirza, M. R.; Nicum, S.; O'Donnell, D. M.; Pautier, P.; Rodolakis, A.; Sehouli, J.; Selcukbiricik, F.; Singh, N.; Tan, D. S. P.; Timmerman, D.; Tognon, G.; van der Velden, J.; Witteveen, P. O.; Zeimet, A. G. (Lippincott Williams & Wilkins, 2019-05)
    The development of guidelines is one of the core activities of the European Society for Medical Oncology (ESMO) and European Society of Gynaecologial Oncology (ESGO), as part of the mission of both societies to improve the ...
  • Antenatal Workup of Early Megacystis and Selection of Candidates for Fetal Therapy 
    Fontanella, Federica; Duin, Leonie; Adama Van Scheltema, Phebe N.; Cohen-Overbeek, Titia E.; Pajkrt, Eva; Bekker, Mireille; Willekes, Christine; Bax, Caroline J.; Oepkes, Dick; Bilardo, Catia M. (S. Karger AG, 2019-03-01)
    To investigate the best criteria for discriminating fetuses with isolated posterior urethral valves from those theoretically not eligible for fetal treatment because of complex megacystis, high chance of spontaneous ...
  • Development of Nationwide Recommendations to Support Prenatal Counseling in Extreme Prematurity 
    Geurtzen, Rosa; Van Heijst, Arno F.J.; Draaisma, Jos M.T.; Kuijpers, Lindie J.M.K.; Woiski, Mallory; Scheepers, Hubertina C.J.; Van Kaam, Anton H.; Oudijk, Martijn A.; Lafeber, Harrie N.; Bax, Caroline J.; Koper, Jan F.; Duin, Leonie K.; Van der Hoeven, Marc A.; Kornelisse, René F.; Duvekot, Johannes J.; Andriessen, Peter; Van Runnard Heimel, Pieter J.; Van der Heide-Jalving, Marja; Bekker, Mireille N.; Mulder-De Tollenaer, Susanne M.; Van Eyck, Jim; Eshuis-Peters, Ellis; Graatsma, Margo; Hermens, Rosella P.M.G.; Hogeveen, Marije (American Academy of Pediatrics, 2019-06)
    OBJECTIVES: To develop a nationwide, evidence-based framework to support prenatal counseling in extreme prematurity, focusing on organization, decision-making, content, and style aspects. METHODS: A nationwide multicenter ...
  • How Do Different Forms of Vascular Brain Injury Relate to Cognition in a Memory Clinic Population: The TRACE-VCI Study 
    Boomsma, Jooske M F; Exalto, Lieza G; Barkhof, Frederik; Berg, Esther van den; Bresser, Jeroen de; Heinen, Rutger; Leeuwis, Anna E; Prins, Niels D; Scheltens, Philip; Weinstein, Henry C; van der Flier, Wiesje M; Biessels, Geert Jan; The TRACE-VCI study group (IOS Press, 2019-03-18)
    Memory clinic patients frequently present with different forms of vascular brain injury due to different etiologies, often co-occurring with Alzheimer's disease (AD) pathology. Objective: We studied how cognition was ...
  • One-fits-all pretreatment protocol facilitating Fluorescence In Situ Hybridization on formalin-fixed paraffin-embedded, fresh frozen and cytological slides 
    Richardson, Shivanand O; Huibers, Manon M H; de Weger, Roel A; de Leng, Wendy W J; Hinrichs, John W J; Meijers, Ruud W J; Willems, Stefan M; Peeters, Ton L M G (BioMed Central, 2019)
    Background: The Fluorescence In Situ Hybridization (FISH) technique is a very useful tool for diagnostic and prognostic purposes in molecular pathology. However, clinical testing on patient tissue is challenging due to ...
  • Direct-infusion based metabolomics unveils biochemical profiles of inborn errors of metabolism in cerebrospinal fluid 
    Haijes, Hanneke A; van der Ham, Maria; Gerrits, Johan; van Hasselt, Peter M; Prinsen, Hubertus C M T; de Sain-van der Velden, Monique G M; Verhoeven-Duif, Nanda M; Jans, Judith J M (Academic Press Inc., 2019-05-01)
    Background: For inborn errors of metabolism (IEM), metabolomics is performed for three main purposes: 1)development of next generation metabolic screening platforms, 2)identification of new biomarkers in predefined patient ...
  • Focal epilepsy with fear-related behavior as primary presentation in Boerboel dogs 
    Stassen, Quirine E M; Grinwis, Guy C M; van Rhijn, Nieke C; Beukers, Martjin; Verhoeven-Duif, Nanda M; Leegwater, Peter A J (Wiley-Blackwell, 2019-03)
    BACKGROUND: Focal seizures with fear as a primary ictal manifestation, their diagnostic challenges, and impact on quality of life are well described in human medicine. Reports focusing on ictal fear-like behavior in animals ...