Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

  • Clinical Evaluation and Validation of the Dutch Crosslinking for Keratoconus Score 
    Wisse, Robert P.L.; Simons, Rob W.P.; Van Der Vossen, Martijn J.B.; Muijzer, Marc B.; Soeters, Nienke; Nuijts, Rudy M.M.A.; Godefrooij, Daniel A. (American Medical Association, 2019-06-01)
    Importance: Defining keratoconus progression is fundamental in clinical decision making because crosslinking treatments are indicated when the disease is considered progressive. Currently, there is no consensus which ...
  • Octreotide for gastrointestinal bleeding in hereditary hemorrhagic telangiectasia: A prospective case series 
    Kroon, Steven; Snijder, Repke J.; Mager, Johannes J.; Post, Martijn C.; Tenthof van Noorden, Jacco; van Geenen, Erwin J.M.; Drenth, Joost P.H.; Grooteman, Karina V. (John Wiley & Sons Inc., 2019-07-09)
  • A Stimuli-Responsive Nanocomposite for 3D Anisotropic Cell-Guidance and Magnetic Soft Robotics 
    Tognato, Riccardo; Armiento, Angela R.; Bonfrate, Valentina; Levato, Riccardo; Malda, Jos; Alini, Mauro; Eglin, David; Giancane, Gabriele; Serra, Tiziano (Wiley-VCH Verlag, 2019-02-28)
    Stimuli-responsive materials have the potential to enable the generation of new bioinspired devices with unique physicochemical properties and cell-instructive ability. Enhancing biocompatibility while simplifying the ...
  • Dutch Translation and Adaptation of the Treatment Beliefs Questionnaire for Chronic Pain Rehabilitation 
    Wittink, Harriët; Oosterhaven, Janke; Dekker, Jos; Kruitwagen, Cas; Devillé, Walter; Ellens, Else; Schroder, Carin (John Wiley & Sons Inc., 2019-06-27)
    Background: The Treatment Beliefs Questionnaire has been developed to measure patients' beliefs of necessity of and concerns about rehabilitation. Preliminary evidence suggests that these beliefs may be associated with ...
  • Quantification of Double Stranded DNA Breaks and Telomere Length as Proxies for Corneal Damage and Replicative Stress in Human Keratoconus Corneas 
    Wisse, Robert P.L.; Kuiper, Jonas J.W.; Radstake, Timothy R.D.; Broen, Jasper C.A. (Association for Research in Vision and Ophthalmology Inc., 2019-07)
    Purpose: The pathogenesis of keratoconus (KC) is multifactorial, and associated with oxidative stress and subsequent DNA damage. We investigate differences in DNA damage and replicative stress in patients with KC, and in ...
  • Risk of Rhegmatogenous Retinal Detachment in Acute Retinal Necrosis With and Without Prophylactic Intervention 
    Risseeuw, Sara; de Boer, Joke H.; ten Dam – van Loon, Ninette H.; van Leeuwen, Redmer (Elsevier, 2019-10-01)
    Purpose: To study whether preventive laser or preventive vitrectomy is able to lower the risk of rhegmatogenous retinal detachment (RRD) in patients with acute retinal necrosis (ARN). Design: A retrospective, interventional ...
  • Prolonged Cone b-Wave on Electroretinography Is Associated with Severity of Inflammation in Noninfectious Uveitis 
    Brouwer, Anna H.; de Wit, Gerard C.; ten Dam, Ninette H.; Wijnhoven, Ralph; van Genderen, Maria M.; de Boer, Joke H. (Elsevier, 2019-11)
    Purpose: This study sought to investigate retinal function in patients with noninfectious uveitis by using full-field electroretinography (ERG) and correlate the ERG to disease duration and severity of inflammation. Design: ...
  • Cartilage evaluation in finger joints in healthy controls and early hand osteoarthritis patients using high-resolution MRI 
    Saltzherr, M. S.; Muradin, G. S.R.; Haugen, I. K.; Selles, R. W.; van Neck, J. W.; Coert, J. H.; Hazes, J. M.W.; Luime, J. J. (W.B. Saunders Ltd, 2019-08-01)
    Objective: To compare direct evaluation of cartilage with high resolution MRI (hrMRI) to indirect cartilage evaluation using MRI inter-bone distance in hand OA patients and healthy controls. Design: 41 hand OA patients and ...
  • Geen kanker, maar een sjanker 
    Prins, Fieke M.; Lock, M. T.W.T.; Stillebroer, Alexander B.; Dik, Pieter; van der Meer, Gretha T. (Bohn Stafleu van Loghum, 2019-07-18)
    BACKGROUND: Syphilis (lues) is a sexually transmitted infection caused by the spirochete Treponema pallidum. In adolescents, the diagnosis of primary syphilis can be made promptly by taking a sexual medical history and ...
  • The Osteoinductive Effect of Controlled Bone Morphogenic Protein 2 Release Is Location Dependent 
    Olthof, Maurits G.L.; Lu, Lichun; Tryfonidou, Marianna A.; Loozen, Loek D.; Pouran, Behdad; Yaszemski, Michael J.; Meij, Björn P.; Dhert, Wouter J.A.; Alblas, Jacqueline; Kempen, Diederik H.R. (Mary Ann Liebert Inc., 2019-02-01)
    The main challenge in bone morphogenic protein 2 (BMP-2)-based application lies in finding strategies that prolong its effective period as it has a short biological half-life. Several BMP-2 release profiles have shown to ...
  • The role of bacterial stimuli in inflammation-driven bone formation 
    Croes, M.; Kruyt, M. C.; Boot, W.; Pouran, B.; Braham, M. V.; Pakpahan, S. A.; Weinans, H.; Vogely, H. C.; Fluit, A. C.; Dhert, W. J.; Alblas, J.; Öner, F. C. (Forum Multimedia Publishing LLC, 2019-05-16)
    Immune cells and their soluble factors regulate skeletal cells during normal bone regeneration and pathological bone formation. Bacterial infections can trigger immune responses that activate pro-osteogenic pathways, but ...
  • Willingness of patients to use unused medication returned to the pharmacy by another patient: a cross-sectional survey 
    Bekker, Charlotte; van den Bemt, Bart; Egberts, Toine CG; Bouvy, Marcel; Gardarsdottir, Helga (BMJ Publishing Group, 2019-05-14)
    OBJECTIVES: Redispensing by pharmacies of medication unused by another patient could contribute to optimal use of healthcare resources. This study aimed to assess patient willingness to use medication returned by another ...
  • Allocation to highly sensitized patients based on acceptable mismatches results in low rejection rates comparable to nonsensitized patients 
    Heidt, Sebastiaan; Haasnoot, Geert W.; Witvliet, Marian D.; van der Linden-van Oevelen, Marissa J.H.; Kamburova, Elena G.; Wisse, Bram W.; Joosten, Irma; Allebes, Wil A.; van der Meer, Arnold; Hilbrands, Luuk B.; Baas, Marije C.; Spierings, Eric; Hack, Cornelis E.; van Reekum, Franka E.; van Zuilen, Arjan D.; Verhaar, Marianne C.; Bots, Michiel L.; Drop, Adriaan C.A.D.; Plaisier, Loes; Seelen, Marc A.J.; Sanders, Jan Stephan; Hepkema, Bouke G.; Lambeck, Annechien J.A.; Bungener, Laura B.; Roozendaal, Caroline; Tilanus, Marcel G.J.; Voorter, Christina E.; Wieten, Lotte; van Duijnhoven, Elly M.; Gelens, Marielle A.C.J.; Christiaans, Maarten H.L.; van Ittersum, Frans J.; Nurmohamed, Shaikh A.; Lardy, Neubury M.; Swelsen, Wendy; van der Pant, Karlijn A.M.I.; van der Weerd, Neelke C.; ten Berge, Ineke J.M.; Bemelman, Frederike J.; Hoitsma, Andries; van der Boog, Paul J.M.; de Fijter, Johan W.; Betjes, Michiel G.H.; Otten, Henny G.; Roelen, Dave L.; Claas, Frans H.J. (Elsevier, 2019-10)
    Whereas regular allocation avoids unacceptable mismatches on the donor organ, allocation to highly sensitized patients within the Eurotransplant Acceptable Mismatch (AM) program is based on the patient's HLA phenotype plus ...
  • Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine 
    Groenland, Stefanie L; Mathijssen, Ron H J; Beijnen, Jos H; Huitema, Alwin D R; Steeghs, Neeltje (Springer-Verlag, 2019-09-01)
    PURPOSE: While in the era of precision medicine, the right drug for each patient is selected based on molecular tumor characteristics, most novel oral targeted anticancer agents are still being administered using a ...
  • Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study 
    Baumeister, Sebastian E; Schlesinger, Sabrina; Aleksandrova, Krasimira; Jochem, Carmen; Jenab, Mazda; Gunter, Marc J; Overvad, Kim; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Fournier, Agnès; Kühn, Tilman; Kaaks, Rudolf; Pischon, Tobias; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; La Vecchia, Carlo; Masala, Giovanna; Panico, Salvatore; Fasanelli, Francesca; Tumino, Rosario; Grioni, Sara; Bueno de Mesquita, Bas; Vermeulen, Roel; May, Anne M; Borch, Kristin B; Oyeyemi, Sunday O; Ardanaz, Eva; Rodríguez-Barranco, Miguel; Dolores Chirlaque López, María; Felez-Nobrega, Mireia; Sonestedt, Emily; Ohlsson, Bodil; Hemmingsson, Oskar; Werner, Mårten; Perez-Cornago, Aurora; Ferrari, Pietro; Stepien, Magdalena; Freisling, Heinz; Tsilidis, Konstantinos K; Ward, Heather; Riboli, Elio; Weiderpass, Elisabete; Leitzmann, Michael F (Elsevier, 2019-05)
    Background & Aims: To date, evidence on the association between physical activity and risk of hepatobiliary cancers has been inconclusive. We examined this association in the European Prospective Investigation into Cancer ...
  • Cardiac Function After Radiation Therapy for Breast Cancer 
    van den Bogaard, Veerle A B; van Luijk, Peter; Hummel, Yoran M; van der Meer, Peter; Schuit, E; Boerman, Liselotte M; Maass, Saskia W M C; Nauta, Jan F; Steggink, Lars C; Gietema, Jourik A; de Bock, Geertruida H; Berendsen, Annette J; Smit, Wilma G J M; Sijtsema, Nanna M; Kierkels, Roel G J; Langendijk, Johannes A; Crijns, Anne P G; Maduro, John H (Elsevier, 2019-06-01)
    Purpose: The main purpose of this study was to test the hypothesis that incidental cardiac irradiation is associated with changes in cardiac function in breast cancer (BC) survivors treated with radiation therapy (RT). ...
  • Association of menopausal characteristics and risk of coronary heart disease: A pan-European case-cohort analysis 
    Dam, Veerle; Van Der Schouw, Yvonne T.; Onland-Moret, N. Charlotte; Groenwold, Rolf H.H.; Peters, Sanne A.E.; Burgess, Stephen; Wood, Angela M.; Chirlaque, Maria Dolores; Moons, Karel G.M.; Oliver-Williams, Clare; Schuit, Ewoud; Tikk, Kaja; Weiderpass, Elisabete; Holm, Marianne; Tjønneland, Anne; Kühn, Tilman; Fortner, Renée T.; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Ferrari, Pietro; Gunter, Marc; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Panico, Salvatore; Boer, Jolanda M.A.; Monique Verschuren, W. M.; Salamanca-Fernández, Elena; Arriola, Larraitz; Moreno-Iribas, Conchi; Engström, Gunnar; Melander, Olle; Nordendahl, Maria; Wennberg, Patrik; Key, Timothy J.; Colorado-Yohar, Sandra; Matullo, Giuseppe; Overvad, Kim; Clavel-Chapelon, Francoise; Boeing, Heiner; Ramon Quiros, J.; Di Angelantonio, Emanuele; Langenberg, Claudia; Sweeting, Michael J.; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Butterworth, Adam (Oxford University Press, 2019-08-01)
    Background: Earlier age at menopause has been associated with increased risk of coronary heart disease (CHD), but the shape of association and role of established cardiovascular risk factors remain unclear. Therefore, we ...
  • Does pneumococcal conjugate vaccination affect onset and risk of first acute otitis media and recurrences?: A primary care-based cohort study 
    Fortanier, Alexandre C; Venekamp, Roderick P; Hoes, Arno W; Schilder, Anne G M (Elsevier, 2019-03-07)
    Background: It has been hypothesized that widespread implementation of pneumococcal conjugate vaccination (PCV) in infancy reduces early AOM and thereby prevents further AOM episodes and associated health care resource ...
  • Dairy Product Intake and Risk of Type 2 Diabetes in EPIC-InterAct: A Mendelian Randomization Study 
    Vissers, Linda E.T.; Sluijs, Ivonne; van der Schouw, Yvonne T.; Forouhi, Nita G.; Imamura, Fumiaki; Burgess, Stephen; Barricarte, Aurelio; Boeing, Heiner; Bonet, Catalina; Chirlaque, Maria Dolores; Fagherazzi, Guy; Franks, Paul W.; Freisling, Heinz; Gunter, Marc J.; Ramón Quirós, J.; Ibsen, Daniel B.; Kaaks, Rudolf; Key, Timothy; Khaw, Kay T.; Kühn, Tilman; Mokoroa, Olatz; Nilsson, Peter M.; Overvad, Kim; Pala, Valeria; Palli, Domenico; Panico, Salvatore; Sacerdote, Carlotta; Spijkerman, Annemieke M.W.; Tjonneland, Anne; Tumino, Rosario; Rodríguez-Barranco, Miguel; Rolandsson, Olov; Riboli, Elio; Sharp, Stephen J.; Langenberg, Claudia; Wareham, Nicholas J. (American Diabetes Association Inc., 2019-04-01)
    OBJECTIVE To estimate the causal association between intake of dairy products and incident type 2 diabetes. RESEARCH DESIGN AND METHODS The analysis included 21,820 European individuals (9,686 diabetes cases) of the European ...
  • Potential benefit of MRI-guided IMRT for flank irradiation in pediatric patients with Wilms' tumor 
    Guerreiro, F; Seravalli, E; Janssens, G O; van den Heuvel-Eibrink, M M; Lagendijk, J J W; Raaymakers, B W (Informa Healthcare, 2019-02-01)
    PURPOSE/OBJECTIVE: Flank irradiation for Wilms' tumor (WT) is currently performed at our institute using a cone-beam computed tomography-guided volumetric modulated arc (VMATCBCT) workflow. By adding real-time magnetic ...