Recently added

DSpace/Manakin Repository

UMC Repository: Recent submissions

  • Muscle diffusion tensor imaging in glycogen storage disease V (McArdle disease) 
    Rehmann, R.; Schlaffke, L.; Froeling, M.; Kley, R. A.; Kuehnle, E.; De Marees, M.; Forsting, J.; Rohm, M.; Tegenthoff, M.; Schmidt-Wilcke, T.; Vorgerd, M. (Springer-Verlag, 2019-06)
    PURPOSE: To evaluate differences in diffusion parameters in thigh muscles in patients with glycogen storage disease type V (McArdle disease) using muscle diffusion tensor imaging (mDTI) compared to healthy controls METHODS: ...
  • The value of a 1-day multidisciplinary robot surgery training for novice robot surgeons 
    Beulens, Alexander J.W.; Brinkman, Willem M.; Porte, Petra J.; Meijer, Richard P.; van Merriënboer, Jeroen J.G.; Van der Poel, Henk G.; Wagner, Cordula (Springer London, 2019-06-01)
    Introduction: To fulfil the need for a basic level of competence in robotic surgery (Brinkman et al., Surg Endosc Other Interv Tech 31(1):281–287, 2017; Dutch Health inspectorate (Inspectie voor de gezondheidszorg), ...
  • Comparing signal-to-noise ratio for prostate imaging at 7T and 3T 
    Steensma, Bart R.; Luttje, Mariska; Voogt, Ingmar J.; Klomp, Dennis W.J.; Luijten, Peter R.; van den Berg, Cornelis A.T.; Raaijmakers, Alexander J.E. (John Wiley & Sons Inc., 2019-05)
    Background: In MRI, the signal-to-noise ratio (SNR) theoretically increases with B0 field strength. However, because of attenuation of the radiofrequency (RF) fields at 7T, it is not certain if this SNR gain can be realized ...
  • Preliminary evidence for cerebral capillary shunting in adults with sickle cell anemia 
    Juttukonda, Meher R; Donahue, Manus J.; Davis, Larry T; Gindville, Melissa C; Lee, Chelsea A; Patel, Niral J; Kassim, Adetola A; Pruthi, Sumit; Hendrikse, Jeroen; Jordan, Lori C. (SAGE Publications Inc., 2019-06-01)
    Elevated flow velocities in adults with sickle cell anemia (SCA) may cause rapid erythrocyte transit through capillaries. This phenomenon could present as dural venous sinus hyperintensity on arterial spin labeling (ASL)-MRI ...
  • Regulation of spindle assembly checkpoint signalling and silencing during mitosis 
    Kuijt, Timoteo Enrique Felipe (Utrecht University, 2020-02-20)
    The development, growth and maintenance of a healthy body depends on structural replenishment and renewal of cells, the units of which our body is composed. Through cell division or mitosis, one mother cell splits into two ...
  • Engineering Gelatin-Based Biomatrices for Pre-vascularisation of Bone Analogues 
    Klotz, Barbara Judith (Utrecht University, 2020-02-07)
    The current treatment to replace a large missing bone segment is by transplantation with autologous tissue. Such reconstructive surgeries are accompanied by long operation times and donor site morbidity. To overcome these ...
  • Design, safety and applications of radio-frequency antennas for ultra-high field MRI of the body 
    Steensma, Bart Romke (Utrecht University, 2019-01-16)
    Researchers in the field of MRI (Magnetic resonance imaging) are pushing towards the use of stronger and stronger magnets in MRI scanners. These extremely strong magnets are used because the signal-to-noise ratio in MRI ...
  • Intra-tumoral holmium-166 therapy: Feasibility in head and neck cancer 
    Bakker, Robbert Christiaan (Utrecht University, 2020-01-15)
    Head and neck cancer (HNC) has a high incidence, the prognosis in case of advanced stage disease is poor, and over the past decades, the overall survival has only slightly increased. This thesis, provide insight into the ...
  • Check Your Checklist: The Danger of Over- and Underestimating the Quality of Economic Evaluations 
    Frederix, Geert W J (Springer International Publishing, 2019-12)
  • Estimating Morbidity Rates Based on Routine Electronic Health Records in Primary Care: Observational Study 
    Nielen, Mark M. J.; Spronk, Inge; Davids, Rodrigo; Korevaar, Joke C.; Poos, Rene; Hoeymans, Nancy; Opstelten, Wim; van der Sande, Marianne A. B.; Biermans, Marion C. J.; Schellevis, Francois G.; Verheij, Robert A. (JMIR Publications Inc., 2019-07-26)
    Background: Routinely recorded electronic health records (EHRs) from general practitioners (GPs) are increasingly available and provide valuable data for estimating incidence and prevalence rates of diseases in the population. ...
  • Powerful testing via hierarchical linkage disequilibrium in haplotype association studies 
    Balliu, Brunilda; Houwing-Duistermaat, Jeanine J.; Böhringer, Stefan (Wiley-VCH Verlag, 2019-05-01)
    Marginal tests based on individual SNPs are routinely used in genetic association studies. Studies have shown that haplotype-based methods may provide more power in disease mapping than methods based on single markers when, ...
  • Estimating Constraints for Protection Factors from HDX-MS Data 
    Skinner, Simon P.; Radou, Gael; Tuma, Roman; Houwing-Duistermaat, Jeanine J.; Paci, Emanuele (Elsevier, 2019-04-02)
    Hydrogen/deuterium exchange monitored by mass spectrometry is a promising technique for rapidly fingerprinting structural and dynamical properties of proteins. The time-dependent change in the mass of any fragment of the ...
  • Role of timing of exposure to pets and dampness or mould on asthma and sensitization in adolescence 
    Milanzi, Edith B; Koppelman, Gerard H; Smit, Henriette A; Wijga, Alet H; Vonk, Judith M; Brunekreef, Bert; Gehring, Ulrike (Wiley-Blackwell, 2019-10)
    BACKGROUND: Pet and dampness or mould exposure are considered risk factors for asthma and sensitization. It is unclear whether timing of exposure to these factors is differentially associated with asthma risk and sensitization ...
  • The pathways from parental and neighbourhood socioeconomic status to adolescent educational attainment: An examination of the role of cognitive ability, teacher assessment, and educational expectations 
    Weinberg, Dominic; Stevens, Gonneke W J M; Finkenauer, Catrin; Brunekreef, Bert; Smit, Henriëtte A; Wijga, Alet H (Public Library of Science, 2019-05-22)
    Adolescents with high educational attainment generally have better outcomes across the lifespan than adolescents with lower educational attainment. This study investigated how three measures of socioeconomic status ...
  • Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA) 
    Burton, Martin J; Pollard, Andrew J; Ramsden, James D; Chong, Lee-Yee; Venekamp, Roderick P (John Wiley & Sons Inc., 2019-12-30)
    BACKGROUND: Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome is a rare clinical syndrome of unknown cause usually identified in children. Tonsillectomy is considered a potential ...
  • Safety of switching from vitamin K antagonist to non-vitamin K antagonist oral anticoagulant in frail elderly with atrial fibrillation: rationale and design of the FRAIL-AF randomised controlled trial 
    Joosten, Linda P T; van Doorn, Sander; Hoes, Arno W; Nierman, Melchior C; Wiersma, Nynke M; Koek, Huiberdina L; Hemels, Martin E W; Huisman, Menno V; Roes, Kit C; van den Bor, Rutger M; Buding, Wim F; Rutten, Frans H; Geersing, Geert-Jan (BMJ Publishing Group, 2019-12-29)
    INTRODUCTION: Clinical guidelines recommend non-vitamin K antagonist oral anticoagulants (NOACs) over vitamin K antagonists (VKAs) for stroke prevention in most patients with atrial fibrillation (AF). Frail elderly were ...
  • Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells 
    Fontaine, Margaux A.C.; Westra, Marijke M.; Bot, Ilze; Jin, Han; Franssen, Aimée J.P.M.; Bot, Martine; de Jager, Saskia C.A.; Dzhagalov, Ivan; He, You Wen; van Vlijmen, Bart J.M.; Gijbels, Marion J.J.; Reutelingsperger, Chris P.; van Berkel, Theo J.C.; Sluimer, Judith C.; Temmerman, Lieve; Biessen, Erik A.L. (Nature Publishing Group, 2019-10-10)
    The anti-apoptotic protein myeloid cell leukemia 1 (Mcl-1) plays an important role in survival and differentiation of leukocytes, more specifically of neutrophils. Here, we investigated the impact of myeloid Mcl-1 deletion ...
  • Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells 
    Frodermann, Vanessa; Rohde, David; Courties, Gabriel; Severe, Nicolas; Schloss, Maximilian J.; Amatullah, Hajera; McAlpine, Cameron S.; Cremer, Sebastian; Hoyer, Friedrich F.; Ji, Fei; van Koeverden, Ian D.; Herisson, Fanny; Honold, Lisa; Masson, Gustavo Santos; Zhang, Shuang; Grune, Jana; Iwamoto, Yoshiko; Schmidt, Stephen P.; Wojtkiewicz, Gregory R.; Lee, I. Hsiu; Gustafsson, Karin; Pasterkamp, Gerard; de Jager, Saskia C.A.; Sadreyev, Ruslan I.; MacFadyen, Jean; Libby, Peter; Ridker, Paul; Scadden, David T.; Naxerova, Kamila; Jeffrey, Kate L.; Swirski, Filip K.; Nahrendorf, Matthias (Nature Research, 2019-11-01)
    A sedentary lifestyle, chronic inflammation and leukocytosis increase atherosclerosis; however, it remains unclear whether regular physical activity influences leukocyte production. Here we show that voluntary running ...
  • Self-Management Education for Bipolar Disorders: A Hermeneutic-Phenomenological Study on the Tacit Knowledge of Mental Health Nurses 
    van den Heuvel, S. C.G.H.; Goossens, P. J.J.; Terlouw, C.; Schoonhoven, L.; van Achterberg, T. (Informa Healthcare, 2019-11-02)
    Background: Self-management of bipolar disorder (BD) education is a complex nursing intervention in which patients and informal caregivers are taught to be actively involved in self-monitoring and self-regulating activities. ...
  • Heterogeneity of Colorectal Cancer Risk Factors by Anatomical Subsite in 10 European Countries: A Multinational Cohort Study 
    Murphy, Neil; Ward, Heather A.; Jenab, Mazda; Rothwell, Joseph A.; Boutron-Ruault, Marie Christine; Carbonnel, Franck; Kvaskoff, Marina; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Aleksandrova, Krasimira; Weiderpass, Elisabete; Skeie, Guri; Borch, Kristin Benjaminsen; Tjønneland, Anne; Kyrø, Cecilie; Overvad, Kim; Dahm, Christina C.; Jakszyn, Paula; Sánchez, Maria Jose; Gil, Leire; Huerta, José M.; Barricarte, Aurelio; Quirós, J. Ramón; Khaw, Kay Tee; Wareham, Nick; Bradbury, Kathryn E.; Trichopoulou, Antonia; La Vecchia, Carlo; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Fasanelli, Francesca; Panico, Salvatore; Bueno-de-Mesquita, Bas; Peeters, Petra H.; Gylling, Björn; Myte, Robin; Jirström, Karin; Berntsson, Jonna; Xue, Xiaonan; Riboli, Elio; Cross, Amanda J.; Gunter, Marc J. (W.B. Saunders, 2019-06-01)
    Background & Aims: Colorectal cancer located at different anatomical subsites may have distinct etiologies and risk factors. Previous studies that have examined this hypothesis have yielded inconsistent results, possibly ...