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Now showing items 19501-19520 of 40729

Multiparametric Renal MRI: An Intrasubject Test-Retest Repeatability Study

de Boer, Anneloes; Harteveld, Anita A.; Stemkens, Bjorn; Blankestijn, Peter J.; Bos, Clemens; Franklin, Suzanne L.; Froeling, Martijn; Joles, Jaap A.; Verhaar, Marianne C.; van den Berg, Nico; Hoogduin, Hans; Leiner, Tim (John Wiley & Sons Inc., 2021-03)

BACKGROUND: Renal multiparametric magnetic resonance imaging (MRI) is a promising tool for diagnosis, prognosis, and treatment monitoring in kidney disease. PURPOSE: To determine intrasubject test-retest repeatability of ...
Risk factors for calcification of the vertebrobasilar arteries in cardiovascular patients referred for a head CT, the SMART study

UCC-SMART-Studygroup (Elsevier Masson, 2021-06)

BACKGROUND AND PURPOSE: Vertebrobasilar artery calcification (VBAC) has been associated with increased stroke occurrence. Little is known on VBAC risk factors, especially for patients with cardiovascular disease. We aimed ...
Risk factors and clinical outcomes of endoscopic dilation in benign esophageal strictures: a long-term follow-up study

Vermeulen, Bram D.; de Zwart, Merle; Sijben, Jasmijn; Soons, Elsa; van der Weerd, Lucie; Arese, Daniele; von den Hoff, Daan W.; Craviotto, Vincenzo; Tan, Adriaan C.I.T.L.; Groenen, Marcel J.M.; Bogte, Auke; Repici, Alessandro; Spaander, Manon C.W.; Siersema, Peter D. (Mosby Inc., 2020-05)

Background and Aims: Endoscopic dilation (ED) is still the mainstay of therapeutic management of benign esophageal strictures (BESs). This study aimed to establish risk factors for refractory BESs and assess long-term ...
Assessment of motor unit loss in patients with spinal muscular atrophy

Sleutjes, Boudewijn T.H.M.; Wijngaarde, Camiel A.; Wadman, Renske I.; Otto, Louise A.M.; Asselman, Fay Lynn; Cuppen, Inge; van den Berg, Leonard H.; Ludo van der Pol, W.; Stephan Goedee, H. (Elsevier Ireland Ltd, 2020-06)

Objective: To assess motor unit (MU) changes in patients with spinal muscular atrophy (SMA) using compound muscle action potential (CMAP) scans. Methods: We performed CMAP scan recordings in median nerves of 24 treatment-naïve ...
Man-vrouwverschillen in de optimale dosering van medicatie voor hartfalen: De 'one-size-fits-all'-aanpak van richtlijnen lijkt aan herziening toe

Groenewegen, Amy; Mosterd, Arend; Rutten, Frans H. (Bohn Stafleu van Loghum, 2020-03-17)

Er zijn legio aanwijzingen dat de verschillen tussen mannelijke en vrouwelijke fysiologie leiden tot verschillen in farmacokinetiek. Het lijkt waarschijnlijk dat de farmacokinetische verschillen tussen mannen en vrouwen ...
Clinical recommendations for cardiopulmonary exercise testing in children with respiratory diseases

Takken, Tim; Sonbahar Ulu, Hazal; Hulzebos, Erik Hj (Taylor and Francis Ltd., 2020-07-02)

Introduction: Cardiopulmonary exercise testing (CPET) quantitates and qualitates the integrated physiological response of a person to incremental exercise and provides additional information compared to static lung function ...
Socio-ecological correlates of physical activity in breast and colon cancer survivors 4 years after participation in a randomized controlled exercise trial (PACT study)

Hiensch, Anouk E; Peeters, Petra H M; Jansen, Marijke; van der Wall, Elsken; Backx, Frank J G; Velthuis, Miranda J; May, Anne M (Public Library of Science, 2020-04)

Having a physically active lifestyle after cancer diagnosis is beneficial for health, and this needs to be continued into survivorship to optimize long-term benefits. We found that patients, who participated in an 18-week ...
Long-Term in Vivo Performance of Low-Temperature 3D-Printed Bioceramics in an Equine Model

Bolaños, Rafael Vindas; Castilho, Miguel; De Grauw, Janny; Cokelaere, Stefan; Plomp, Saskia; Groll, Jürgen; Van Weeren, P. René; Gbureck, Uwe; Malda, Jos (American Chemical Society, 2020-03-09)

Bone has great self-healing capacity, but above a certain critical size, bone defects will not heal spontaneously, requiring intervention to achieve full healing. Among the synthetic calcium phosphate (CaP) bone replacement ...
Intraoperative Optical Coherence Tomography-Assisted Descemet Membrane Endothelial Keratoplasty: Toward More Efficient, Safer Surgery

Muijzer, Marc B; Soeters, Nienke; Godefrooij, Daniel A; van Luijk, Chantal M; Wisse, Robert P L (Lippincott Williams & Wilkins, 2020-06)

PURPOSE: To evaluate the clinical value of intraoperative optical coherence tomography (iOCT) and prolonged overpressure in Descemet membrane endothelial keratoplasty for surgical safety, efficiency, and outcome. METHODS: ...
Management of Unruptured Cerebral Aneurysms and Arteriovenous Malformations

Ruigrok, Ynte M. (Lippincott Williams and Wilkins Ltd., 2020-04-01)

PURPOSE OF REVIEW: Unruptured intracranial aneurysms and brain arteriovenous malformations (AVMs) may be detected as incidental findings on cranial imaging. This article provides a practical approach to the management of ...
Movement behavior remains stable in stroke survivors within the first two months after returning home

Wondergem, Roderick; Pisters, Martijn F; Heijmans, Martijn W; Wouters, Eveline J M; de Bie, Rob A; Veenhof, Cindy; Visser-Meily, Johanna M A (Public Library of Science, 2020)

BACKGROUND AND PURPOSE: The aim of this study is to investigate changes in movement behaviors, sedentary behavior and physical activity, and to identify potential movement behavior trajectory subgroups within the first two ...
Using machine learning to predict mental healthcare consumption in non-affective psychosis

GROUP Investigators (Elsevier, 2020-04)

OBJECTIVE: The main goal of the study was to predict individual patients' future mental healthcare consumption, and thereby enhancing the design of an efficient demand-oriented mental healthcare system by focusing on a ...
Low-Density Lipoprotein Cholesterol Target Attainment in Patients With Established Cardiovascular Disease: Analysis of Routine Care Data

Groenhof, T Katrien J; Kofink, Daniel; Bots, Michiel L; Nathoe, Hendrik M; Hoefer, Imo E; Van Solinge, Wouter W; Lely, A Titia; Asselbergs, Folkert W; Haitjema, Saskia (JMIR Publications Inc., 2020-04-02)

BACKGROUND: Direct feedback on quality of care is one of the key features of a learning health care system (LHS), enabling health care professionals to improve upon the routine clinical care of their patients during practice. ...
Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms

Hodskinson, Michael R.; Bolner, Alice; Sato, Koichi; Kamimae-Lanning, Ashley N.; Rooijers, Koos; Witte, Merlijn; Mahesh, Mohan; Silhan, Jan; Petek, Maya; Williams, David M.; Kind, Jop; Chin, Jason W.; Patel, Ketan J.; Knipscheer, Puck (Nature Research, 2020-03-26)

Acetaldehyde is a highly reactive, DNA-damaging metabolite that is produced upon alcohol consumption1. Impaired detoxification of acetaldehyde is common in the Asian population, and is associated with alcohol-related ...
The Moderate Alcohol and Cardiovascular Health Trial (MACH15): Design and methods for a randomized trial of moderate alcohol consumption and cardiometabolic risk

Spiegelman, Donna; Lovato, Laura C; Khudyakov, Polyna; Wilkens, Trine L; Adebamowo, Clement A; Adebamowo, Sally N; Appel, Lawrence J; Beulens, Joline Wj; Coughlin, Janelle W; Dragsted, Lars Ove; Edenberg, Howard J; Eriksen, Jane N; Estruch, Ramon; Grobbee, Diederick E; Gulayin, Pablo E; Irazola, Vilma; Krystal, John H; Lazo, Mariana; Murray, Margaret M; Rimm, Eric B; Schrieks, Ilse C; Williamson, Jeff D; Mukamal, Kenneth J (Oxford University Press, 2020-12)

Background: Observational studies have documented lower risks of coronary heart disease and diabetes among moderate alcohol consumers relative to abstainers, but only a randomized clinical trial can provide conclusive ...
Colonic mucosal kinase activity, cytokine and chemokine profiles in inflammatory bowel disease

Brand, E.; Roosenboom, B.; Fernandez, B. Malvar; Lutter, L.; van Koolwijk, E.; van Lochem, E. G.; Horje, C. S. Horjus Talabur; Reedquist, K. A.; van Wijk, F.; Oldenburg, B. (Elsevier, 2020-01)

Background With the approval of tofacitinib, an oral Janus Kinase (JAK) inhibitor, modulation of kinase activity has been added to the therapeutic armamentarium of inflammatory bowel disease (IBD). Despite its established ...
Development of Mucosal PNAd+ and MAdCAM-1+ Venules during Disease Course in Ulcerative Colitis

Roosenboom, Britt; Lochem, Ellen G van; Meijer, Jos; Smids, Carolijn; Nierkens, Stefan; Brand, Eelco C; Erp, Liselot W van; Kemperman, Larissa G J M; Groenen, Marcel J M; Horje, Carmen S Horjus Talabur; Wahab, Peter J (Multidisciplinary Digital Publishing Institute (MDPI), 2020-04-06)

PNAd and MAdCAM-1 addressins on venules are of importance in T-cell homing and potential therapeutic targets in ulcerative colitis (UC). Normally, PNAd+ high endothelial venules (HEVs) are only present in lymphoid organs, ...
The balancing perspective of hard-to-reach hepatitis C patients who were lost to follow-up: A qualitative study

Kracht, Patricia A M; Arends, Joop E; Hoepelman, Andy I M; Vervoort, Sigrid C J M (Public Library of Science, 2020-04-13)

BACKGROUND: In the foreseeable future, patients with hepatitis C virus (HCV) with good healthcare access will all have been cured and the lost to follow-up (LFU) HCV-population will increasingly exist of hard-to-reach ...
Prospective Validation of Gallium-68 Prostate Specific Membrane Antigen-Positron Emission Tomography/Computerized Tomography for Primary Staging of Prostate Cancer. Reply: Prospective validation of Gallium-68 PSMA-PET/CT in primary staging of prostate

van Kalmthout, Ludwike; van Melick, Harm; Lavalaye, Jules; Meijer, Richard; Kooistra, Anko; de Klerk, John; Braat, Arthur; Kaldeway, Peter; de Keizer, Bart; Lam, Marnix (Elsevier, 2021-06-01)
Movement behaviour patterns in adults with haemophilia

Timmer, Merel A; Veenhof, Cindy; de Kleijn, Piet; de Bie, Rob A; Schutgens, Roger E G; Pisters, Martijn F (SAGE Publications Inc., 2020-03)

Background: Joint bleeds are the hallmark of haemophilia, and can lead to disabling haemophilic arthropathy. Consequently, the movement behaviour of adults with haemophilia differs from that of healthy adults. It seems ...

Now showing items 19501-19520 of 40729