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Predicting anxiety in hospitalized cancer patients

van den Brekel, Lieke; van der Baan, Frederieke H; Zweers, Danielle; Koldenhof, José J; Vos, J Bernard H; de Graeff, Alexander; Witteveen, Petronella O; Teunissen, Saskia C C M (Elsevier, 2020-09)

Context: Anxiety in patients with cancer is highly prevalent; yet it remains underestimated and inadequately assessed. Little is known about predictors for anxiety in hospitalized patients with cancer. Insight in predictors ...
Neonatal sepsis: need for consensus definition, collaboration and core outcomes

Molloy, Eleanor J; Wynn, J L; Bliss, J; Koenig, J M; Keij, Fleur M.; McGovern, M; Simons, S H P; van den Hoogen, A; Boode, W.P.; Schlapbach, Luregn Jan; Reiss, Irwin K M (Lippincott Williams & Wilkins, 2020-07-01)
Endothelial and Inflammation Biomarker Profiles at Diagnosis Reflecting Clinical Heterogeneity and Serving as a Prognostic Tool for Treatment Response in Two Independent Cohorts of Patients With Juvenile Dermatomyositis

Wienke, Judith; Pachman, Lauren M; Morgan, Gabrielle A; Yeo, Joo Guan; Amoruso, Maria C; Hans, Victoria; Kamphuis, Sylvia S M; Hoppenreijs, Esther P A H; Armbrust, Wineke; van den Berg, J Merlijn; Hissink Muller, Petra C E; Gelderman, Kyra A; Arkachaisri, Thaschawee; van Wijk, Femke; van Royen-Kerkhof, Annet (John Wiley & Sons Inc., 2020-07)

OBJECTIVE: Juvenile dermatomyositis (DM) is a heterogeneous systemic immune-mediated vasculopathy. This study was undertaken to 1) identify inflammation/endothelial dysfunction-related biomarker profiles reflecting disease ...
100 Olanzapine/Samidorphan for Schizophrenia: Weight Gain and Metabolic Outcomes in Phase 3 ENLIGHTEN-2 and Subsequent Long-Term, Open-Label Safety Study

Correll, Christoph U; Newcomer, John W; Silverman, Bernard; DiPetrillo, Lauren; Graham, Christine; Jiang, Ying; Du, Yangchun; Simmons, Adam; Hopkinson, Craig; McDonnell, David; Kahn, Rene (Cambridge University Press, 2020-04-01)

BACKGROUND: Opioid antagonists may mitigate medication-associated weight gain and/or metabolic dysregulation. ENLIGHTEN-2 evaluated a combination of olanzapine and the opioid antagonist samidorphan (OLZ/SAM) vs olanzapine ...
Cannabinoids and psychotic symptoms: A potential role for a genetic variant in the P2X purinoceptor 7 (P2RX7) gene

Boks, Marco P; He, Yujie; Schubart, Chris D; van Gastel, Willemijn; Elkrief, Laurent; Huguet, Guillaume; van Eijk, Kristel; Vinkers, Christiaan H; Kahn, René S; Paus, Tomás; Conrod, Patricia; Hol, Elly M; de Witte, Lot D (Academic Press Inc., 2020-08)

To investigate the biological mechanisms underlying the higher risk for psychosis in those that use cannabis, we conducted a genome-wide environment-interaction study (GWEIS). In a sample of individuals without a psychiatric ...
The resolution revolution: Comparing spikes and high frequency oscillations in high-density and standard intra-operative electrocorticography of the same patient

Zweiphenning, Willemiek J E M; van Diessen, Eric; Aarnoutse, Erik J; Leijten, Frans S S; van Rijen, Peter C; Braun, Kees P J; Zijlmans, Maeike (Elsevier Ireland Ltd, 2020-05-01)
A new microfluidic model that allows monitoring of complex vascular structures and cell interactions in a 3D biological matrix

van Dijk, Christian G M; Brandt, Maarten M; Poulis, Nikolaos; Anten, Jonas; van der Moolen, Matthijs; Kramer, Liana; Homburg, Erik F G A; Louzao-Martinez, Laura; Pei, Jiayi; Krebber, Merle M; van Balkom, Bas W M; de Graaf, Petra; Duncker, Dirk J; Verhaar, Marianne C; Luttge, Regina; Cheng, Caroline (Royal Society of Chemistry, 2020-05-19)

Microfluidic organ-on-a-chip designs are used to mimic human tissues, including the vasculature. Here we present a novel microfluidic device that allows the interaction of endothelial cells (ECs) with pericytes and the ...
The safety and efficacy of a new 20-mm lumen apposing metal stent (lams) for the endoscopic treatment of pancreatic and peripancreatic fluid collections: a large international, multicenter study

Anderloni, Andrea; Fabbri, Carlo; Nieto, Jose; Uwe, Will; Dollhopf, Markus; Aparicio, José Ramón; Perez-Miranda, Manuel; Tarantino, Ilaria; Arlt, Alexander; Vleggaar, Frank; Vanbiervliet, Geoffrey; Hampe, Jochen; Kahaleh, Michel; Vila, Juan J; Dayyeh, Barham K Abu; Storm, Andrew C; Fugazza, Alessandro; Binda, Cecilia; Charachon, Antoine; Sevilla-Ribota, Sergio; Tyberg, Amy; Robert, Moran; Wani, Sachin; Repici, Alessandro; Sethi, Amrita; Khashab, Mouen A; Kunda, Rastislav (Springer New York, 2021-04)

BACKGROUND: Lumen apposing metal stent (LAMS) allows an easy access to peripancreatic fluid collections (PPFCs) and the possibility of performing direct endoscopic necrosectomy (DEN). The aim of our study was to evaluate ...
Cerebral palsy after very preterm birth - an imaging perspective

Gano, Dawn; Cowan, Frances M; de Vries, Linda S (W.B. Saunders Ltd, 2020-06)

Neonatal brain imaging undoubtedly can provide the most accurate information from which to determine whether cerebral palsy is likely to affect an individual infant born preterm. The sensitivity and specificity of that ...
Higher dosage of ciprofloxacin necessary in critically ill patients: a new dosing algorithm based on renal function and pathogen susceptibility

Gieling, Emilie M; Wallenburg, Eveline; Frenzel, Tim; de Lange, Dylan W; Schouten, Jeroen A; Ten Oever, Jaap; Kolwijck, Eva; Burger, David M; Pickkers, Peter; Ter Heine, Rob; Brüggemann, Roger J M (Wiley-Blackwell, 2020-10-01)

The objective of the present study was to develop a dosing algorithm for ciprofloxacin based on both renal function and pathogen susceptibility in critically ill patients. In this observational prospective multicenter ...
Hyperthermia exacerbates the acute effects of psychoactive substances on neuronal activity measured using microelectrode arrays (MEAs) in rat primary cortical cultures in vitro

Zwartsen, Anne; Hondebrink, Laura; de Lange, Dylan W; Westerink, Remco H S (Academic Press Inc., 2020-06-15)

Hyperthermia is a well-known, potentially life-threatening, side effect of stimulant psychoactive substances that worsens the neurological outcome of hospitalized patients. However, current in vitro methods to assess the ...
Compatibility at amino acid position 98 of MICB reduces the incidence of graft-versus-host disease in conjunction with the CMV status

Carapito, Raphael; Aouadi, Ismail; Pichot, Angélique; Spinnhirny, Perrine; Morlon, Aurore; Kotova, Irina; Macquin, Cécile; Rolli, Véronique; Cesbron, Anne; Gagne, Katia; Oudshoorn, Machteld; van der Holt, Bronno; Labalette, Myriam; Spierings, Eric; Picard, Christophe; Loiseau, Pascale; Tamouza, Ryad; Toubert, Antoine; Parissiadis, Anne; Dubois, Valérie; Paillard, Catherine; Maumy-Bertrand, Myriam; Bertrand, Frédéric; von dem Borne, Peter A; Kuball, Jürgen H E; Michallet, Mauricette; Lioure, Bruno; Peffault de Latour, Régis; Blaise, Didier; Cornelissen, Jan J; Yakoub-Agha, Ibrahim; Claas, Frans; Moreau, Philippe; Charron, Dominique; Mohty, Mohamad; Morishima, Yasuo; Socié, Gérard; Bahram, Seiamak (Springer Nature, 2020-07)

Graft-versus-host disease (GVHD) and cytomegalovirus (CMV)-related complications are leading causes of mortality after unrelated-donor hematopoietic cell transplantation (UD-HCT). The non-conventional MHC class I gene MICB, ...
The predictive and prognostic value of low skeletal muscle mass for dose-limiting toxicity and survival in head and neck cancer patients receiving concomitant cetuximab and radiotherapy

Huiskamp, L. F.J.; Chargi, N.; Devriese, L. A.; de Jong, P. A.; de Bree, R. (Springer-Verlag, 2020-10)

Purpose: This study aims to investigate the predictive value of low skeletal muscle mass (SMM) for cetuximab dose-limiting toxicity (DLT) and its prognostic value in head and neck squamous cell carcinoma (HNSCC) patients ...
Cerebral cortical microinfarcts: A novel MRI marker of vascular brain injury in patients with heart failure

Heart-Brain Connection Consortium (Elsevier Ireland Ltd, 2020-07-01)

BACKGROUND: Patients with heart failure (HF) are at risk for vascular brain injury. Cerebral cortical microinfarcts (CMIs) are a novel MRI marker of vascular brain injury. This study aims to determine the occurrence of ...
Interventions for rapid recognition and treatment of sepsis in the emergency department: a narrative review

Uffen, J. W.; Oosterheert, J. J.; Schweitzer, V. A.; Thursky, K.; Kaasjager, H. A.H.; Ekkelenkamp, M. B. (Elsevier, 2021-02)

Background: Sepsis is a major cause of morbidity and mortality worldwide. Early recognition and treatment of sepsis is associated with improved outcome. The emergency department (ED) is the department where patients with ...
Incidence and costs of hospitalized adult influenza patients in The Netherlands: a retrospective observational study

Marbus, Sierk D.; Schweitzer, Valentijn A.; Groeneveld, Geert H.; Oosterheert, Jan J.; Schneeberger, Peter M.; van der Hoek, Wim; van Dissel, Jaap T.; van Gageldonk-Lafeber, Arianne B.; Mangen, Marie Josée (Springer-Verlag, 2020-07)

Objective: Influenza virus infections cause a high disease and economic burden during seasonal epidemics. However, there is still a need for reliable disease burden estimates to provide a more detailed picture of the impact ...
T2 relaxation-time mapping in healthy and diseased skeletal muscle using extended phase graph algorithms

Keene, Kevin R; Beenakker, Jan-Willem M; Hooijmans, Melissa T; Naarding, Karin J; Niks, Erik H; Otto, Louise A M; van der Pol, W Ludo; Tannemaat, Martijn R; Kan, Hermien E; Froeling, Martijn (John Wiley & Sons Inc., 2020-11)

PURPOSE: Multi-echo spin-echo (MSE) transverse relaxometry mapping using multi-component models is used to study disease activity in neuromuscular disease by assessing the T2 of the myocytic component (T2water ). Current ...
Diffusion tensor imaging of the anterior cruciate ligament following primary repair with internal bracing: A longitudinal study

Van Dyck, Pieter; Froeling, Martijn; Heusdens, Christiaan H W; Sijbers, Jan; Ribbens, Annemie; Billiet, Thibo (John Wiley & Sons Inc., 2021-06)

Diffusion tensor imaging (DTI) provides information about tissue microstructure and its degree of organization by quantifying water diffusion. We aimed to monitor longitudinal changes in DTI parameters (fractional isotropy, ...
Long-term effects of ivacaftor on nonpulmonary outcomes in individuals with cystic fibrosis, heterozygous for a S1251N mutation

Burghard, M.; Berkers, G.; Ghijsen, S.; Hollander-Kraaijeveld, F. M.; de Winter-de Groot, K. M.; van der Ent, C. K.; Heijerman, H. G.M.; Takken, T.; Hulzebos, H. J. (John Wiley & Sons Inc., 2020-06)

Objectives: To describe the long-term effects of ivacaftor (Kalydeco®) in individuals with cystic fibrosis (CF) on body mass index (BMI), body composition (BC), pulmonary function (PF), resting energy expenditure (REE), ...
Natural history of lung function in spinal muscular atrophy

Wijngaarde, Camiel A.; Veldhoen, Esther S.; van Eijk, Ruben P.A.; Stam, Marloes; Otto, Louise A.M.; Asselman, Fay Lynn; Wösten-van Asperen, Roelie M.; Hulzebos, Erik H.J.; Verweij-van den Oudenrijn, Laura P.; Bartels, Bart; Cuppen, Inge; Wadman, Renske I.; van den Berg, Leonard H.; van der Ent, Cornelis K.; van der Pol, W. Ludo (BioMed Central, 2020-04-10)

BACKGROUND: Respiratory muscle weakness is an important feature of spinal muscular atrophy (SMA). Progressive lung function decline is the most important cause of mortality and morbidity in patients. The natural history ...

Now showing items 19461-19480 of 40729