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Is it accurate to classify ALS as a neuromuscular disorder?

van Es, Michael A; Goedee, H Stephan; Westeneng, Henk-Jan; Nijboer, Tanja C W; van den Berg, Leonard H (Taylor and Francis Ltd., 2020-09)

Introduction: Amyotrophic lateral sclerosis (ALS) is a fatal disorder characterized by the progressive loss of upper and lower motor neurons. ALS has traditionally been classified within the domain of neuromuscular diseases, ...
Current trends in the clinical trial landscape for amyotrophic lateral sclerosis

van Eijk, Ruben P A; Kliest, Tessa; van den Berg, Leonard H (Lippincott Williams & Wilkins, 2020-10)

PURPOSE OF REVIEW: To review the current developments in the design and conduct of clinical trials for amyotrophic lateral sclerosis (ALS), illustrated by a critical appraisal of ClinicalTrials.gov. RECENT FINDINGS: In ...
Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage in Patients With a History of Migraine

van Os, Hendrikus J A; Ruigrok, Ynte M; Verbaan, Dagmar; Dennesen, Paul; Müller, Marcella C A; Coert, Bert A; Algra, Ale; Vergouwen, Mervyn D I; Wermer, Marieke J H (Lippincott Williams & Wilkins, 2020-10)

Background and Purpose: Delayed cerebral ischemia (DCI) is a major contributor to the high morbidity in patients with aneurysmal subarachnoid hemorrhage (aSAH). Spreading depolarizations may play a role in DCI pathophysiology. ...
GRADE guidelines: 21 part 2. Test accuracy: inconsistency, imprecision, publication bias, and other domains for rating the certainty of evidence and presenting it in evidence profiles and summary of findings tables

GRADE Working Group (Elsevier, 2020-06)

Objectives: This article provides updated GRADE guidance about how authors of systematic reviews and health technology assessments and guideline developers can rate the certainty of evidence (also known as quality of the ...
Potential impact of missing outcome data on treatment effects in systematic reviews: imputation study

Kahale, Lara A; Khamis, Assem M; Diab, Batoul; Chang, Yaping; Lopes, Luciane Cruz; Agarwal, Arnav; Li, Ling; Mustafa, Reem A; Koujanian, Serge; Waziry, Reem; Busse, Jason W; Dakik, Abeer; Schünemann, Holger J; Hooft, Lotty; Scholten, Rob Jpm; Guyatt, Gordon H; Akl, Elie A (BMJ Publishing Group, 2020-08-26)

AbstractObjective To assess the risk of bias associated with missing outcome data in systematic reviews. Design Imputation study. Setting Systematic reviews. Population 100 systematic reviews that included a group level ...
Meta-Analyses Proved Inconsistent in How Missing Data Were Handled Across Their Included Primary Trials: A Methodological Survey

Kahale, Lara A; Khamis, Assem M; Diab, Batoul; Chang, Yaping; Lopes, Luciane Cruz; Agarwal, Arnav; Li, Ling; Mustafa, Reem A; Koujanian, Serge; Waziry, Reem; Busse, Jason W; Dakik, Abeer; Hooft, Lotty; Guyatt, Gordon H; Scholten, Rob J P M; Akl, Elie A (Dove Medical Press Ltd., 2020)

Background: How systematic review authors address missing data among eligible primary studies remains uncertain. Objective: To assess whether systematic review authors are consistent in the way they handle missing data, ...
Development of a Checklist to Assist Physiotherapists in Determination of Patients' Suitability for a Blended Treatment

Kloek, Corelien J J; Janssen, Joep; Veenhof, Cindy (Mary Ann Liebert Inc., 2020-08-01)

Background: The integration of digital applications within health care is called blended care. Introduction: Despite its potential, physiotherapists experience difficulty in determining which patients are suitable for ...
Discriminative validity of the Core outcome set functional independence in a population of older adults

Dockx, Yvonne J C; Molenaar, Esther A L M; Barten, Di-Janne J A; Veenhof, Cindy (BioMed Central, 2020-08-26)

Background: Clinicians are currently challenged to support older adults to maintain a certain level of Functional Independence (FI). FI is defined as "functioning physically safely and independent from another person, ...
Do therapist effects determine outcome in patients with shoulder pain in a primary care physiotherapy setting?

Kooijman, Margit K.; Buining, Elisah M.; Swinkels, Ilse C.S.; Koes, Bart W.; Veenhof, Cindy (Elsevier, 2020-06)

Objectives: To explore whether a therapist effect exists in physiotherapists treating patients with shoulder pain and to identify if personality traits of the physiotherapist influences patients outcome. Design: Observational ...
One in six physiotherapy practices in primary care offer musculoskeletal ultrasound - An explorative survey

Kooijman, Margit K.; Swinkels, Ilse C.S.; Koes, Bart W.; De Bakker, Dinny; Veenhof, Cindy (BioMed Central, 2020-03-24)

Background: The first aim of this research was to investigate the current prevalence of musculoskeletal ultrasound in Dutch physiotherapy practices. The second aim was to explore experiences of physiotherapists with ...
Feasibility of a stratified blended physiotherapy intervention for patients with non-specific low back pain: a mixed methods study

van Tilburg, Mark L.; Kloek, Corelien J.J.; Staal, J. Bart; Bossen, Daniël; Veenhof, Cindy (Informa Healthcare, 2022-02-01)

Introduction: Integrating web-based or mobile components and face-to-face components within a treatment process is called blended care. As part of the participatory development of a blended physiotherapeutic intervention ...
Effectiveness of Anticoagulation in Critically Ill Patients With Antiphospholipid Syndrome Immortal Time Bias in Cox Proportional Hazard Model Reply

Pineton de Chambrun, Marc; Mathian, Alexis; Donker, Dirk W; Luyt, Charles-Edouard; Combes, Alain; Amoura, Zahir (Elsevier, 2020-07)
Venoarterial Extracorporeal Membrane Oxygenation: If You Cannot Measure It, You Cannot Improve It

Shekar, Kiran; Donker, Dirk W; Brodie, Daniel (Lippincott Williams & Wilkins, 2020-10)
Powerful spin-offs … fostering flexibility, creativity and individualised critical care!

Donker, D. W. (Netherlands Society of Intensive Care, 2020-05)
Harmonization of diffusion MRI data sets with adaptive dictionary learning

St-Jean, Samuel; Viergever, Max A; Leemans, Alexander (Wiley-Liss Inc., 2020-11-01)

Diffusion magnetic resonance imaging can indirectly infer the microstructure of tissues and provide metrics subject to normal variability in a population. Potentially abnormal values may yield essential information to ...
Comparison of three PD-L1 immunohistochemical assays in head and neck squamous cell carcinoma (HNSCC)

de Ruiter, Emma J.; Mulder, Frans J.; Koomen, Bregje M.; Speel, Ernst Jan; van den Hout, Mari F.C.M.; de Roest, Reinout H.; Bloemena, Elisabeth; Devriese, Lot A.; Willems, Stefan M. (Elsevier, 2021-06)

Expression of programmed cell death-ligand 1 (PD-L1) is being used as predictive biomarker for immunotherapy in head and neck squamous cell carcinoma (HNSCC). Several antibodies are available for PD-L1 testing and multiple ...
Deep learning for automatic calcium scoring in CT: Validation using multiple cardiac CT and chest CT protocols

van Velzen, Sanne G.M.; Lessmann, Nikolas; Velthuis, Birgitta K.; Bank, Ingrid E.M.; van den Bongard, Desiree H.J.G.; Leiner, Tim; de Jong, Pim A.; Veldhuis, Wouter B.; Correa, Adolfo; Terry, James G.; Carr, John Jeffrey; Viergever, Max A.; Verkooijen, Helena M.; Išgum, Ivana (Radiological Society of North America Inc., 2020-04)

Background Although several deep learning (DL) calcium scoring methods have achieved excellent performance for specific CT protocols, their performance in a range of CT examination types is unknown. Purpose To evaluate the ...
Meerwaarde van MRI-screening bij zeer dicht borstweefsel in het bevolkingsonderzoek borstkanker

de Lange, Stéphanie V.; Bakker, Marije F.; Pijnappel, Ruud M.; Mann, Ritse M.; Peeters, Petra H.M.; Monninkhof, Evelyn M.; Emaus, Marleen J.; Loo, Claudette E.; Bisschops, Robertus H.C.; Lobbes, Marc B.I.; de Jong, Mathijn D.F.; Duvivier, Katya M.; Veltman, Jeroen; Karssemeijer, Nico; de Koning, Harry J.; van Diest, Paul J.; Mali, Willem P.T.M.; van den Bosch, Maurice A.A.J.; Veldhuis, Wouter B.; van Gils, Carla H. (Bohn Stafleu van Loghum, 2020-04)

Doel Het onderzoeken van de aanvullende waarde van MRI-screening voor de reductie van intervalkankers in het bevolkingsonderzoek borstkanker bij vrouwen met zeer dicht borstweefsel. Opzet Multicentrische gerandomiseerde, ...
Anti-tumor necrosis factor therapy in patients with inflammatory bowel disease; comorbidity, not patient age, is a predictor of severe adverse events

Asscher, Vera E R; van der Vliet, Quirine; van der Aalst, Karen; van der Aalst, Anniek; Brand, Eelco C; van der Meulen-de Jong, Andrea E; Oldenburg, Bas; Pierik, Marieke J; van Tuyl, Bas; Mahmmod, Nofel; Maljaars, P W Jeroen; Fidder, Herma H; Dutch ICC (Springer-Verlag, 2020-12)

Purpose: To assess safety and effectiveness of anti-tumor necrosis factor (anti-TNF) therapy in IBD patients ≥ 60 years. Methods: Ninety IBD patients ≥ 60 years at initiation of anti-TNF therapy, 145 IBD patients ≥ 60 years ...
BIOFABRICATION OF LIVER CONSTRUCTS FOR DRUG TOXICITY STUDIES

Schneeberger, Kerstin; Bouwmeester, Manon; Levato, Riccardo; Kramer, Nynke; Malda, Jos; Spee, Bart (Japanese Society for the Study of Xenobiotics, 2020)

Now showing items 18681-18700 of 40729