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UMC Repository: Recent submissions

  • Prevalence of chronic kidney disease and risk factors in North-Central Nigeria: a population-based survey 
    Ilorin Renal Study Group (BioMed Central, 2020-11-10)
    Background: Chronic kidney disease (CKD) is a growing challenge in low- and middle-income countries, particularly in sub-Saharan Africa. There is insufficient population-based data on CKD in Nigeria that is required to ...
  • Consensus-based recommendations for the management of juvenile systemic sclerosis 
    Foeldvari, Ivan; Culpo, Roberta; Sperotto, Francesca; Anton, Jordi; Avcin, Tadej; Baildam, Eileen; Boros, Christina; Chaitow, Jeffrey; Constantin, Tamas; Kasapcopur, Ozgur; Knupp Feitosa de Oliveira, Sheila; Pilkington, Clarissa; Toplak, Natasa; van Royen, Annet; Saad Magalhaes, Claudia; Vastert, Sebastiaan J; Wulffraat, Nico; Zulian, Francesco (Oxford University Press, 2021-04-01)
    Juvenile systemic sclerosis (JSSc) is a rare disease of childhood and currently no international consensus exists with regard to its assessment and treatment. This SHARE (Single Hub and Access point for paediatric Rheumatology ...
  • Parents’ Perspectives and Societal Acceptance of Implementation of Newborn Screening for SCID in the Netherlands 
    on behalf of the SONNET-Study Group (Springer New York, 2021-01)
    Purpose: While neonatal bloodspot screening (NBS) for severe combined immunodeficiency (SCID) has been introduced more than a decade ago, implementation in NBS programs remains challenging in many countries. Even if ...
  • Patient‐reported outcomes after 10‐year follow‐up of intensive, multifactorial treatment in individuals with screen‐detected type 2 diabetes:: the ADDITION‐Europe trial 
    Dalsgaard, E. M.; Sandbæk, A.; Griffin, S. J.; Rutten, G. E.H.M.; Khunti, K.; Davies, M. J.; Irving, G. J.; Vos, R. C.; Webb, D. R.; Wareham, N. J.; Witte, D. R. (Wiley-Blackwell, 2020-09)
    Aims: To present the longer-term impact of multifactorial treatment of type 2 diabetes on self-reported health status, diabetes-specific quality of life, and diabetes treatment satisfaction at 10-year follow up of the ...
  • Sports participation of patients with haemophilia in the COVID-19 era: The Dutch experience 
    Versloot, Olav; van der Net, Janjaap; Fischer, Kathelijn (Wiley-Blackwell, 2021-03)
  • Bleeding risk of haemodialysis and peritoneal dialysis patients 
    van Eck van der Sluijs, Anita; Abrahams, Alferso C; Rookmaaker, Maarten B; Verhaar, Marianne C; Bos, Willem Jan W; Blankestijn, Peter J; Dekker, Friedo W; van Diepen, Merel; Ocak, Gurbey (Oxford University Press, 2021-01-01)
    BACKGROUND: Dialysis patients have an increased bleeding risk as compared with the general population. However, there is limited information whether bleeding risks are different for patients treated with haemodialysis (HD) ...
  • Plasma Methylglyoxal Levels Are Associated With Amputations and Mortality in Severe Limb Ischemia Patients With and Without Diabetes 
    Hanssen, Nordin M J; Teraa, Martin; Scheijen, Jean L J M; Van de Waarenburg, Marjo; Gremmels, Hendrik; Stehouwer, Coen D A; Verhaar, Marianne C; Schalkwijk, Casper G (American Diabetes Association Inc., 2021-01-01)
    OBJECTIVE: Diabetes is a risk factor for severe limb ischemia (SLI), a condition associated with high mortality, morbidity, and limb loss. The reactive glucose-derived dicarbonyl methylglyoxal (MGO) is a major precursor ...
  • OX40 Agonist BMS-986178 Alone or in Combination With Nivolumab and/or Ipilimumab in Patients With Advanced Solid Tumors 
    Gutierrez, Martin; Moreno, Victor; Heinhuis, Kimberley M; Olszanski, Anthony J; Spreafico, Anna; Ong, Michael; Chu, Quincy S; Carvajal, Richard D; Trigo, José; Ochoa de Olza, Maria; Provencio, Mariano; De Vos, Filip; de Braud, Filippo; Leong, Stephen; Lathers, Deanne; Wang, Rui; Ravindran, Palani; Feng, Yan; Aanur, Praveen; Melero, Ignacio (American Association for Cancer Research Inc., 2021-01-15)
    PURPOSE: This phase I/IIa study (NCT02737475) evaluated the safety and activity of BMS-986178, a fully human OX40 agonist IgG1 mAb, ± nivolumab and/or ipilimumab in patients with advanced solid tumors. PATIENTS AND METHODS: ...
  • Distraction decreases rIFG-putamen connectivity during goal-directed effort for food rewards 
    Duif, Iris; Wegman, Joost; de Graaf, Kees; Smeets, Paul A M; Aarts, Esther (Nature Publishing Group, 2020-12-01)
    Distracted eating can lead to increased food intake, but it is unclear how. We aimed to assess how distraction affects motivated, goal-directed responses for food reward after satiation. Thirty-eight healthy normal-weight ...
  • Digital pathology in the time of corona 
    Stathonikos, Nikolas; van Varsseveld, Nadege C; Vink, Aryan; van Dijk, Marijke R; Nguyen, Tri Q; Leng, Wendy W J de; Lacle, Miangela M; Goldschmeding, Roel; Vreuls, Celien P H; van Diest, Paul J (BMJ Publishing Group, 2020-11-01)
    The 2020 COVID-19 crisis has had and will have many implications for healthcare, including pathology. Rising number of infections create staffing shortages and other hospital departments might require pathology employees ...
  • Multicenter comparison of Molecular Tumor Boards in the Netherlands: definition, composition, methods and targeted therapy recommendations 
    Koopman, Bart; Groen, Harry J M; Ligtenberg, Marjolijn J L; Grünberg, Katrien; Monkhorst, Kim; de Langen, Adrianus J; Boelens, Mirjam C; Paats, Marthe S; von der Thüsen, Jan H; Dinjens, Winand N M; Solleveld, Nienke; van Wezel, Tom; Gelderblom, Hans; Hendriks, Lizza E; Speel, Ernst Jan M; Theunissen, Tom E; Kroeze, Leonie I; Mehra, Niven; Piet, Berber; van der Wekken, Anthonie J; Ter Elst, Arja; Timens, Wim; Willems, Stefan M; Meijers, Ruud W J; de Leng, Wendy W J; van Lindert, Anne S R; Radonic, Teodora; Hashemi, Sayed M S; Heideman, Daniëlle A M; Schuuring, Ed; van Kempen, Léon C (AlphaMed Press, 2021-08)
    Background: Molecular tumor boards (MTBs) provide rational, genomics-driven, patient-tailored treatment recommendations. Worldwide, MTBs differ in terms of scope, composition, methods, and recommendations. This study aimed ...
  • Acute renal and neurotoxicity due to weight-based dosing of intravenous acyclovir: How to dose in obese patients? 
    Sallevelt, Bastiaan; Smeijsters, Erin; Egberts, Toine; van der Elst, Kim; Mudrikova, T (Elsevier, 2020-10)
    Background Acyclovir is a hydrophilic drug that is mainly distributed in the lean compartments of the body. Consequently, dosing on total body weight in obese patients may lead to drug overdosing. Inconsistency in clinical ...
  • Influence of allopurinol on thiopurine associated toxicity: A retrospective population-based cohort study 
    Houwen, Jeroen P A; Egberts, Antoine C G; de Boer, Anthonius; van Maarseveen, Erik M; Houwen, Roderick H J; Lalmohamed, Arief (Wiley-Blackwell, 2021-05)
    Aims: Thiopurines are important for treating inflammatory bowel disease, but are often discontinued due to adverse effects. Concomitant use of allopurinol might lower the risk of these unwanted effects, but large studies ...
  • Attitudes of Dutch intensive care unit clinicians towards oxygen therapy 
    Grim, C C A; Cornet, A D; Kroner, A; Meiners, A J; Brouwers, A J B W; Reidinga, A C; van Westerloo, D J; Bergmans, D C J J; Gommers, D; Versluis, D; Weller, D; Christiaan Boerma, E; van Driel, E; de Jonge, E; Schoonderbeek, F J; Helmerhorst, H J F; Jongsma-van Netten, H G; Weenink, J; Woittiez, K J; Simons, K S; van Ewelie, L; Petjak, M; Sigtermans, M J; van der Woude, M; Cremer, O L; Bijlstra, P; van der Heiden, P; So, R K L; Vink, R; Jansen, T; de Ruijter, W (Van Zuiden Communications BV, 2020-07)
    BACKGROUND: Over the last decade, there has been an increasing awareness for the potential harm of the administration of too much oxygen. We aimed to describe self-reported attitudes towards oxygen therapy by clinicians ...
  • A Higher Fluid Balance in the Days After Septic Shock Reversal Is Associated With Increased Mortality: An Observational Cohort Study 
    van Mourik, Niels; Geerts, Bart F; Binnekade, Jan M; Veelo, Denise P; Bos, Lieuwe D J; Wiersinga, W Joost; van der Poll, Tom; Cremer, Olaf L; Schultz, Marcus J; Vlaar, Alexander P J (Lippincott Williams & Wilkins, 2020-10)
    Objectives: Previous studies demonstrated that extensive fluid loading and consequently positive fluid balances during sepsis resuscitation are associated with adverse outcome. Yet, the association between fluid balance ...
  • Eosinophilic inflammation in COPD: from an inflammatory marker to a treatable trait 
    David, Benjamin; Bafadhel, Mona; Koenderman, Leo; De Soyza, Antony (BMJ Publishing Group, 2021-02-01)
    The heterogeneity of chronic obstructive pulmonary disease (COPD) creates many diagnostic, prognostic, treatment and management challenges, as the pathogenesis of COPD is highly complex and the underlying cellular and ...
  • Endocrine Health in Childhood Cancer Survivors 
    van Santen, Hanneke M; Chemaitilly, Wassim; Meacham, Lillian R; Tonorezos, Emily S; Mostoufi-Moab, Sogol (W.B. Saunders, 2020-12)
    Endocrine late effects, including reproductive disorders and secondary thyroid cancer, have been reported in up to 50 %childhood cancer survivors (CCS) more than 5 years after treatment. Most endocrine disorders are amenable ...
  • Reproductive Complications in Childhood Cancer Survivors 
    van Santen, Hanneke M; van de Wetering, Marianne D; Bos, Annelies M E; Vd Heuvel-Eibrink, Marry M; van der Pal, Helena J; Wallace, William Hamish (W.B. Saunders, 2020-12)
    Gonadal dysfunction and infertility after cancer treatment are major concerns for childhood cancer survivors and their parents. Uncertainty about fertility or being diagnosed with infertility has a negative impact on quality ...
  • Safety of GH after treatment for childhood cancer 
    van Santen, Hanneke M (Oxford University Press, 2020-12)
  • Evolution of colistin resistance in the Klebsiella pneumoniae complex follows multiple evolutionary trajectories with variable effects on fitness and virulence characteristics 
    Janssen, Axel B; Doorduijn, Dennis J; Mills, Grant; Rogers, Malbert R C; Bonten, Marc J M; Rooijakkers, Suzan H M; Willems, Rob J L; Bengoechea, Jose A; van Schaik, Willem (American Society for Microbiology, 2021-01)
    The increasing prevalence of multidrug-resistant Klebsiella pneumoniae has led to a resurgence in the use of colistin as a last-resort drug. Colistin is a cationic antibiotic that selectively acts on Gram-negative bacteria ...