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Now showing items 17081-17100 of 40729

Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment

Rasmussen, Eva Rye; Hallberg, Pär; Baranova, Ekaterina V; Eriksson, Niclas; Karawajczyk, Malgorzata; Johansson, Caroline; Cavalli, Marco; Maroteau, Cyrielle; Veluchamy, Abirami; Islander, Gunilla; Hugosson, Svante; Terreehorst, Ingrid; Asselbergs, Folkert W; Norling, Pia; Johansson, Hans-Erik; Kohnke, Hugo; Syvänen, Ann-Christine; Siddiqui, Moneeza K; Lang, Chim C; Magnusson, Patrik K E; Yue, Qun-Ying; Wadelius, Claes; von Buchwald, Christian; Bygum, Anette; Alfirevic, Ana; Maitland-van der Zee, Anke H; Palmer, Colin N A; Wadelius, Mia (Springer Nature, 2020-12)

Angioedema in the mouth or upper airways is a feared adverse reaction to angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blocker (ARB) treatment, which is used for hypertension, heart failure and ...
Model selection for metabolomics: predicting diagnosis of coronary artery disease using automated machine learning

Orlenko, Alena; Kofink, Daniel; Lyytikäinen, Leo-Pekka; Nikus, Kjell; Mishra, Pashupati; Kuukasjärvi, Pekka; Karhunen, Pekka J; Kähönen, Mika; Laurikka, Jari O; Lehtimäki, Terho; Asselbergs, Folkert W; Moore, Jason H (Oxford University Press, 2020-03-01)

Motivation: Selecting the optimal machine learning (ML) model for a given dataset is often challenging. Automated ML (AutoML) has emerged as a powerful tool for enabling the automatic selection of ML methods and parameter ...
Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes: A Mendelian Randomization Analysis

Peters, Tricia M; Holmes, Michael V; Richards, J Brent; Palmer, Tom; Forgetta, Vincenzo; Lindgren, Cecilia M; Asselbergs, Folkert W; Nelson, Christopher P; Samani, Nilesh J; McCarthy, Mark I; Mahajan, Anubha; Davey Smith, George; Woodward, Mark; O'Keeffe, Linda M; Peters, Sanne A E (American Diabetes Association Inc., 2021-02)

OBJECTIVE: Observational studies have demonstrated that type 2 diabetes is a stronger risk factor for coronary heart disease (CHD) in women compared with men. However, it is not clear whether this reflects a sex differential ...
Usefulness of a Double-Blind Placebo-Controlled Response Test to Demonstrate Rapid Onset Analgesia with Phenytoin 10% Cream in Polyneuropathy

Kopsky, David J; Vrancken, Alexander F J E; Keppel Hesselink, Jan M; van Eijk, Ruben P A; Notermans, Nicolette C (Dove Medical Press Ltd., 2020)

Purpose: Topical analgesics are an upcoming treatment option for neuropathic pain. In this observational study, we performed a double-blind placebo-controlled response test (DOBRET) in patients with polyneuropathy to ...
Performance and Self-reported Functioning of People With Chronic Idiopathic Axonal Polyneuropathy: A 4-Year Follow-up Study

van Oeijen, Karlijn; Teunissen, Laurien L.; van Leeuwen, Christel; van Opstal, Marleen; José van der Putten, Marie; Notermans, Nicolette C.; van Meeteren, Nico L.U.; Schröder, Carin D. (W.B. Saunders, 2020-11)

Objective: To describe the course of performance of activities (observed and self-reported) of people with chronic idiopathic axonal polyneuropathy (CIAP) over 4 years and to assess the associations with muscle strength, ...
Randomized trial of intravenous immunoglobulin maintenance treatment regimens in chronic inflammatory demyelinating polyradiculoneuropathy

Kuitwaard, K.; Brusse, E.; Jacobs, B. C.; Vrancken, A. F.J.E.; Eftimov, F.; Notermans, N. C.; van der Kooi, A. J.; Fokkink, W. J.R.; Nieboer, D.; Lingsma, H. F.; Merkies, I. S.J.; van Doorn, P. A. (Wiley-Blackwell, 2021-01)

Background and purpose: High peak serum immunoglobulin G (IgG) levels may not be needed for maintenance intravenous immunoglobulin (IVIg) treatment in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and ...
Evolution of renal function and predictive value of serial renal assessments among patients with acute coronary syndrome: BIOMArCS study

BIOMArCS Investigators (Elsevier Ireland Ltd, 2020-01-15)

BACKGROUND: Impaired renal function predicts mortality in acute coronary syndrome (ACS), but its evolution immediately following index ACS and preceding next ACS has not been described in detail. We aimed to describe this ...
Diagnosing arrhythmogenic right ventricular cardiomyopathy by 2010 Task Force Criteria: clinical performance and simplified practical implementation

Bosman, Laurens P; Cadrin-Tourigny, Julia; Bourfiss, Mimount; Aliyari Ghasabeh, Mounes; Sharma, Apurva; Tichnell, Crystal; Roudijk, Rob W; Murray, Brittney; Tandri, Harikrishna; Khairy, Paul; Kamel, Ihab R; Zimmerman, Stefan L; Reitsma, Johannes B; Asselbergs, Folkert W; van Tintelen, J Peter; van der Heijden, Jeroen F; Hauer, Richard N W; Calkins, Hugh; James, Cynthia A; Te Riele, Anneline S J M (Oxford University Press, 2020-05-01)

Aims Arrhythmogenic right ventricular cardiomyopathy (ARVC) is diagnosed by a complex set of clinical tests as per 2010 Task Force Criteria (TFC). Avoiding misdiagnosis is crucial to prevent sudden cardiac death as well ...
Risk Factors and Prevalence of Dilated Cardiomyopathy in Sub-Saharan Africa: Protocol for a Systematic Review

Fundikira, Lulu Said; Chillo, Pilly; van Laake, Linda W; Mutagaywa, Reuben Kato; Schmidt, Amand Floriaan; Kamuhabwa, Appolinary; Kwesigabo, Gideon; Asselbergs, Folkert W (JMIR Publications Inc., 2021-01-21)

Background: Cardiomyopathies, defined as diseases involving mainly the heart muscles, are linked to an estimated 5.9 of 100,000 deaths globally. In sub-Saharan Africa, cardiomyopathies constitute 21.4% of heart failure ...
Quantification of disease progression in spinal muscular atrophy with muscle MRI-a pilot study

Otto, Louise A M; Froeling, Martijn; van Eijk, Ruben P A; Asselman, Fay-Lynn; Wadman, Renske; Cuppen, Inge; Hendrikse, Jeroen; van der Pol, W-Ludo (John Wiley & Sons Inc., 2021-04)

Objectives: Quantitative MRI (qMRI) of muscles is a promising tool to measure disease progression or to assess therapeutic effects in neuromuscular diseases. Longitudinal imaging studies are needed to show sensitivity of ...
Erratum: ESHRE guideline: ovarian stimulation for IVF/ICSI

ESHRE Guideline Group on Ovarian Stimulation (2020)

[This corrects the article DOI: 10.1093/hropen/hoaa009.][This corrects the article DOI: 10.1093/hropen/hoaa009.].
Chloroquine-induced QTc prolongation in COVID-19 patients

van den Broek, M P H; Möhlmann, J E; Abeln, B G S; Liebregts, M; van Dijk, V F; van de Garde, E M W (Bohn Stafleu van Loghum, 2020-07)

BACKGROUND: In the battle against the SARS-CoV‑2 pandemic, chloroquine has emerged as a new potential therapeutic option for the treatment of infected patients. A safety consideration for the application of chloroquine is ...
Developing excellence in biostatistics leadership, training and science in Africa: How the Sub-Saharan Africa Consortium for Advanced Biostatistics (SSACAB) training unites expertise to deliver excellence

Chirwa, Tobias F; Matsena Zingoni, Zvifadzo; Munyewende, Pascalia; Manda, Samuel O; Mwambi, Henry; Kandala, Ngianga-Bakwin; Kinyanjui, Samson; Young, Taryn; Musenge, Eustasius; Simbeye, Jupiter; Musonda, Patrick; Mahande, Michael Johnson; Weke, Patrick; Onyango, Nelson Owuor; Kazembe, Lawrence; Tumwesigye, Nazarius Mbona; Zuma, Khangelani; Yende-Zuma, Nonhlanhla; Omanyondo Ohambe, Marie-Claire; Kweku, Emmanuel Nakua; Maposa, Innocent; Ayele, Birhanu; Achia, Thomas; Machekano, Rhoderick; Thabane, Lehana; Levin, Jonathan; Eijkemans, Marinus J C; Carpenter, James; Chasela, Charles; Klipstein-Grobusch, Kerstin; Todd, Jim (F1000 Research Ltd., 2020-12-22)

The increase in health research in sub-Saharan Africa (SSA) has led to a high demand for biostatisticians to develop study designs, contribute and apply statistical methods in data analyses. Initiatives exist to address ...
Post-stroke cognitive impairment on the Mini-Mental State Examination primarily relates to left middle cerebral artery infarcts

Weaver, Nick A; Kancheva, Angelina K; Lim, Jae-Sung; Biesbroek, J Matthijs; Wajer, Irene Mc Huenges; Kang, Yeonwook; Kim, Beom J; Kuijf, Hugo J; Lee, Byung-Chul; Lee, Keon-Joo; Yu, Kyung-Ho; Biessels, Geert Jan; Bae, Hee-Joon (SAGE Publications Ltd, 2021-10)

Background: Post-stroke cognitive impairment can occur after damage to various brain regions, and cognitive deficits depend on infarct location. The Mini-Mental State Examination (MMSE) is still widely used to assess ...
Quantitative investigation of dose accumulation errors from intra-fraction motion in MRgRT for prostate cancer

Bosma, Lando; Zachiu, Cornel; Ries, Mario G; Denis de Senneville, Baudouin; Raaymakers, Bas W (IOP Publishing Ltd., 2021-03-21)

Accurate spatial dose delivery in radiotherapy is frequently complicated due to changes in the patient's internal anatomy during and in-between therapy segments. The recent introduction of hybrid MRI radiotherapy systems ...
The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants

Mous, Rogier; . (Nature Publishing Group, 2020-12-01)

The inclusion of familial myeloid malignancies as a separate disease entity in the revised WHO classification has renewed efforts to improve the recognition and management of this group of at risk individuals. Here we ...
Surgical anatomy of the upper esophagus related to robot-assisted cervical esophagectomy

Wedel, Thilo; Heinze, Tillmann; Möller, Thorben; van Hillegersberg, Richard; Bleys, Ronald L A W; Weijs, Teun J; van der Sluis, Pieter Christian; Grimminger, Peter P; Sallum, Rubens A; Becker, Thomas; Egberts, Jan-Hendrik (Wiley-Blackwell, 2021-12-24)

Robot-assisted cervical esophagectomy (RACE) enables radical surgery for tumors of the middle and upper esophagus, avoiding a transthoracic approach. However, the cervical access, narrow working space, and complex topographic ...
Five Years of the CC-ERUS Fellowship: A Survey of the Experiences and Post-fellowship Work of the Fellows

Beulens, Alexander J.W.; Dell'Oglio, Paulo; Kiss, Hannah; Brinkman, Willem M.; Larcher, Alessandro; Mottrie, Alexandre; Wagner, Christian; van der Poel, Henk G. (Elsevier, 2020-07)
A Prospective, Observational, Multicentre Study Concerning Nontechnical Skills in Robot-assisted Radical Cystectomy Versus Open Radical Cystectomy

Beulens, Alexander J.W.; Brinkman, Willem M.; Koldewijn, Evert L.; Hendrikx, Ad J.M.; van Basten, Jean Paul A.; van Merriënboer, Jeroen J.G.; Van der Poel, Henk G.; Bangma, Chris H.; Wagner, Cordula (Elsevier, 2020-07)

INTRODUCTION AND HYPOTHESES: valuation of surgical skills, both technical and nontechnical, is possible through observations and video analysis. Besides technical failures, adverse outcomes in surgery can also be related ...
Procedural Surgical RCTs in Daily Practice: Do Surgeons Adopt or Is It Just a Waste of Time?

Oberkofler, Christian E.; Hamming, Jacob F.; Staiger, Roxane D.; Brosi, Philippe; Biondo, Sebastiano; Farges, Olivier; Legemate, Dink A.; Morino, Mario; Pinna, Antonio D.; Pinto-Marques, Hugo; Reynolds, John V.; Campos, Ricardo Robles; Rogiers, Xavier; Soreide, Kjetil; Puhan, Milo A.; Clavien, Pierre Alain; Rinkes, Inne Borel (Lippincott Williams & Wilkins, 2019-11)

OBJECTIVE: To assess the adoption of recommendation from randomized clinical trials (RCTs) and investigate factors favoring or preventing adoption. BACKGROUND: RCT are considered to be the cornerstone of evidence-based ...

Now showing items 17081-17100 of 40729