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Now showing items 15541-15560 of 40729

Radiofrequency ablation and chemotherapy versus chemotherapy alone for locally advanced pancreatic cancer (PELICAN): study protocol for a randomized controlled trial

for the Dutch Pancreatic Cancer Group (BioMed Central, 2021-12)

Background: Approximately 80% of patients with locally advanced pancreatic cancer (LAPC) are treated with chemotherapy, of whom approximately 10% undergo a resection. Cohort studies investigating local tumor ablation with ...
A simplified primary aldosteronism surgical outcome score is a useful prediction model when target organ damage is unknown – Retrospective cohort study

International CONNsortium study group (Elsevier, 2021-05)

Background: Cure of hypertension after adrenalectomy for primary aldosteronism is no certainty and therefore preoperative patient counseling is essential. The Primary Aldosteronism Surgical Outcome (PASO) Score is a useful ...
Complications After Major Surgery for Duodenopancreatic Neuroendocrine Tumors in Patients with MEN1: Results from a Nationwide Cohort

the DutchMEN Study Group (DMSG) (Springer New York, 2021-08)

Background: Little is known about complications after major duodenopancreatic surgery for duodenopancreatic neuroendocrine tumors (dpNETs) in multiple endocrine neoplasia type 1 (MEN1). Therefore, the incidence and severity ...
Information preferences about treatment options in diffuse cutaneous systemic sclerosis: A Delphi consensus study

Spierings, Julia; Nienhuis, Hilde; van Lieshout, Eva; van Laar, Jacob M.; Pieterse, Arwen H. (SAGE Publications Ltd, 2022-02)

Objectives: The aim of this study was to identify and prioritize aspects essential for decision making in patients with diffuse cutaneous systemic sclerosis (dcSSc) and to gain insight into information preferences of ...
Real-time 3D motion estimation from undersampled MRI using multi-resolution neural networks

Terpstra, Maarten; Maspero, Matteo; Bruijnen, T; Verhoeff, Joost; Lagendijk, JJW; van den Berg, CAT (John Wiley & Sons Inc., 2021-11)

Purpose: To enable real-time adaptive magnetic resonance imaging–guided radiotherapy (MRIgRT) by obtaining time-resolved three-dimensional (3D) deformation vector fields (DVFs) with high spatiotemporal resolution and low ...
Risk factors for nodal failure after radiochemotherapy and image-guided brachytherapy in locally advanced cervical cancer: an EMBRACE analysis

EMBRACE Collaborative Group (Elsevier Ireland Ltd, 2021-10)

OBJECTIVE: To assess risk factors for nodal failure (NF) after definitive (chemo)radiotherapy and image-guided brachytherapy for locally advanced cervical cancer (LACC) for patients treated in the EMBRACE I study. MATERIALS ...
Efficacy and safety of cap-assisted endoscopic mucosal resection for treatment of nonlifting colorectal polyps

van der Voort, Veronique R H; Moons, Leon; de Graaf, Wilmar; Schrauwen, Ruud W M; Hazen, Wouter L; Seerden, Tom C; Vleggaar, Frank P; Didden, Paul (Georg Thieme Verlag, 2022-05)

BACKGROUND : Suboptimal lifting increases complexity of endoscopic mucosal resection (EMR) for benign colorectal polyps. Cap-assisted EMR (EMR-C) may allow fibrotic polyp tissue to be captured in the snare. This study ...
Impact of Comorbid Affective Disorders on Longitudinal Clinical Outcomes in Individuals at Ultra-high Risk for Psychosis

EU-GEI High Risk Study Group Authors (Oxford University Press, 2022-01-21)

INTRODUCTION: Diagnoses of anxiety and/or depression are common in subjects at Ultra-High Risk for Psychosis (UHR) and associated with extensive functional impairment. Less is known about the impact of affective comorbidities ...
Successful use of tapering strips for hyperbolic reduction of antidepressant dose: a cohort study

Groot, Peter C; van Os, Jim (SAGE Publications Inc., 2021-08)

Background: Tapering strips facilitate antidepressant discontinuation, allowing for personalised titration of discontinuation to the intensity of withdrawal. A tapering strip consists of antidepressant or other medication, ...
The relationship of symptom dimensions with premorbid adjustment and cognitive characteristics at first episode psychosis: Findings from the EU-GEI study

Ferraro, Laura; La Cascia, Caterina; La Barbera, Daniele; Sanchez-Gutierrez, Teresa; Tripoli, Giada; Seminerio, Fabio; Sartorio, Crocettarachele; Marrazzo, Giovanna; Sideli, Lucia; Arango, Celso; Arrojo, Manuel; Bernardo, Miguel; Bobes, Julio; Del-Ben, Cristina Marta; Gayer-Anderson, Charlotte; Jongsma, Hannah E.; Kirkbride, James B.; Lasalvia, Antonio; Tosato, Sarah; Llorca, Pierre Michel; Menezes, Paulo Rossi; Rutten, Bart P.; Santos, Jose Luis; Sanjuán, Julio; Selten, Jean Paul; Szöke, Andrei; Tarricone, Ilaria; Muratori, Roberto; Tortelli, Andrea; Velthorst, Eva; Rodriguez, Victoria; Quattrone, Andrea; Jones, Peter B.; Van Os, Jim; Vassos, Evangelos; Morgan, Craig; de Haan, Lieuwe; Reininghaus, Ulrich; Cardno, Alastair G.; Di Forti, Marta; Murray, Robin M.; Quattrone, Diego (Elsevier, 2021-10)

Premorbid functioning and cognitive measures may reflect gradients of developmental impairment across diagnostic categories in psychosis. In this study, we sought to examine the associations of current cognition and premorbid ...
Context v. algorithm: Evidence that a transdiagnostic framework of contextual clinical characterization is of more clinical value than categorical diagnosis

Van Os, Jim; Pries, Lotta Katrin; Ten Have, Margreet; De Graaf, Ron; Van Dorsselaer, Saskia; Bak, Maarten; Kenis, Gunter; Lin, Bochao D.; Gunther, Nicole; Luykx, Jurjen J.; Rutten, Bart P.F.; Guloksuz, Sinan (Cambridge University Press, 2023-04-25)

Background A transdiagnostic and contextual framework of 'clinical characterization', combining clinical, psychopathological, sociodemographic, etiological, and other personal contextual data, may add clinical value over ...
The impact of childhood sexual trauma on intimacy and sexuality needs among people with non-affective psychosis

GROUP Investigators (Elsevier, 2021-10)

Background: Childhood trauma, in particular childhood sexual abuse (CSA), and unmet sexuality and intimacy needs are prevalent among people with psychosis spectrum disorders. The association between CSA and sexuality and ...
Is change over time in psychotic symptoms related to social functioning?

GROUP Investigators (SAGE Publications Ltd, 2022-12)

Objective: In psychosis, treatment often focuses on symptom reduction whereas social functioning is also essential. In this study, we investigate positive psychotic symptoms and medication use in relation to social functioning ...
Predicting Future Service Use in Dutch Mental Healthcare: A Machine Learning Approach

van Mens, Kasper; Kwakernaak, Sascha; Janssen, Richard; Cahn, Wiepke; Lokkerbol, Joran; Tiemens, Bea (Springer, 2022-01)

A mental healthcare system in which the scarce resources are equitably and efficiently allocated, benefits from a predictive model about expected service use. The skewness in service use is a challenge for such models. In ...
The Community Assessment of Psychic Experiences: Optimal cut-off scores for detecting individuals with a psychotic disorder

Jaya, Edo S.; van Amelsvoort, Therese; Bartels-Velthuis, Agna A.; Bruggeman, Richard; Cahn, Wiepke; de Haan, Lieuwe; Kahn, Rene S.; van Os, Jim; Schirmbeck, Frederike; Simons, Claudia J.P.; Lincoln, Tania M. (John Wiley & Sons Inc., 2021-12)

Objectives: The need for a brief screening tool for psychosis is widely recognized. The Community Assessment of Psychic Experiences (CAPE) is a popular self-report measure of psychosis, but a cut-off score that can detect ...
Triple therapy for cystic fibrosis Phe508del-gating and -residual function genotypes

Barry, Peter J.; Mall, Marcus A.; Álvarez, Antonio; Colombo, Carla; de Winter-De Groot, Karin M.; Fajac, Isabelle; McBennett, Kimberly A.; McKone, Edward F.; Ramsey, Bonnie W.; Sutharsan, Sivagurunathan; Taylor-Cousar, Jennifer L.; Tullis, Elizabeth; Ahluwalia, Neil; Jun, Lucy S.; Moskowitz, Samuel M.; Prieto-Centurion, Valentin; Tian, Simon; Waltz, David; Xuan, Fengjuan; Zhang, Yaohua; Rowe, Steven M.; Polineni, Deepika (Massachussetts Medical Society, 2021-08-26)

BACKGROUND Elexacaftor-tezacaftor-ivacaftor is a small-molecule cystic fibrosis transmembrane conductance regulator (CFTR) modulator regimen shown to be efficacious in patients with at least one Phe508del allele, which ...
Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study

Cordova, Reynalda; Kliemann, Nathalie; Huybrechts, Inge; Rauber, Fernanda; Vamos, Eszter P.; Levy, Renata Bertazzi; Wagner, Karl Heinz; Viallon, Vivian; Casagrande, Corinne; Nicolas, Geneviève; Dahm, Christina C.; Zhang, Jie; Halkjær, Jytte; Tjønneland, Anne; Boutron-Ruault, Marie Christine; Mancini, Francesca Romana; Laouali, Nasser; Katzke, Verena; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B.; Masala, Giovanna; Grioni, Sara; Panico, Salvatore; van der Schouw, Yvonne T.; Derksen, Jeroen W.G.; Rylander, Charlotta; Skeie, Guri; Jakszyn, Paula; Rodriguez-Barranco, Miguel; Huerta, José María; Barricarte, Aurelio; Brunkwall, Lousie; Ramne, Stina; Bodén, Stina; Perez-Cornago, Aurora; Heath, Alicia K.; Vineis, Paolo; Weiderpass, Elisabete; Monteiro, Carlos Augusto; Gunter, Marc J.; Millett, Christopher; Freisling, Heinz (Churchill Livingstone, 2021-09)

Background: There is a worldwide shift towards increased consumption of ultra-processed foods (UPF) with concurrent rising prevalence of obesity. We examined the relationship between the consumption of UPF and weight gain ...
Bipolar episodes after reproductive events in women with bipolar I disorder, A study of 919 pregnancies

Gilden, Janneke; Poels, Eline M.P.; Lambrichts, Simon; Vreeker, Annabel; Boks, Marco P.M.; Ophoff, Roel A.; Kahn, René S.; Kamperman, Astrid M.; Bergink, Veerle (Elsevier, 2021-12-01)

Background: Women with bipolar I disorder are at high risk for severe episodes after childbirth, but there is no study that provides an overview on bipolar episode risk both during pregnancy and after childbirth, miscarriage ...
Disease management with home telemonitoring aimed at substitution of usual care in the Netherlands: Post-hoc analyses of the e-Vita HF study

Brons, Maaike; Rutten, Frans H.; Zuithoff, Nicolaas P.A.; Oerlemans, Marish I.F.J.; Asselbergs, Folkert W.; Koudstaal, Stefan (Japanese College of Cardiology (Nippon-Sinzobyo-Gakkai), 2022-01)

Background: Home telemonitoring in heart failure (HF) patients may reduce workload of HF nurses by reducing face-to-face contacts. The aim of this study is to assess whether telemonitoring as a substitution could have ...
Perioperative Systemic Therapy vs Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Alone for Resectable Colorectal Peritoneal Metastases: A Phase 2 Randomized Clinical Trial

Rovers, Koen P.; Bakkers, Checca; Nienhuijs, Simon W.; Burger, Jacobus W.A.; Creemers, Geert Jan M.; Thijs, Anna M.J.; Brandt-Kerkhof, Alexandra R.M.; Madsen, Eva V.E.; Van Meerten, Esther; Tuynman, Jurriaan B.; Kusters, Miranda; Versteeg, Kathelijn S.; Aalbers, Arend G.J.; Kok, Niels F.M.; Buffart, Tineke E.; Wiezer, Marinus J.; Boerma, Djamila; Los, Maartje; De Reuver, Philip R.; Bremers, Andreas J.A.; Verheul, Henk M.W.; Kruijff, Schelto; De Groot, Derk Jan A.; Witkamp, Arjen J.; Van Grevenstein, Wilhelmina M.U.; Koopman, Miriam; Nederend, Joost; Lahaye, Max J.; Kranenburg, Onno; Fijneman, Remond J.A.; Van 'T Erve, Iris; Snaebjornsson, Petur; Hemmer, Patrick H.J.; Dijkgraaf, Marcel G.W.; Punt, Cornelis J.A.; Tanis, Pieter J.; De Hingh, Ignace H.J.T. (American Medical Association, 2021-08)

Importance: To date, no randomized clinical trials have investigated perioperative systemic therapy relative to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) alone for resectable colorectal ...

Now showing items 15541-15560 of 40729