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UMC Repository: Recent submissions

  • Dextroamphetamine Treatment in Children With Hypothalamic Obesity 
    van Schaik, Jiska; Welling, Mila S.; de Groot, Corjan J.; van Eck, Judith P.; Juriaans, Alicia; Burghard, Marcella; Oude Ophuis, Sebastianus B.J.; Bakker, Boudewijn; Tissing, Wim J.E.; Schouten-van Meeteren, Antoinette Y.N.; van den Akker, Erica L.T.; van Santen, Hanneke M. (Frontiers Media S. A., 2022-03-09)
    Introduction: Hypothalamic obesity (HO) in children has severe health consequences. Lifestyle interventions are mostly insufficient and currently no drug treatment is approved for children with HO. Amphetamines are known ...
  • Oncofertility Perspectives for Girls with Cancer 
    van der Perk, M. E.Madeleine; van der Kooi, Anne Lotte L.F.; Bos, Annelies M.E.; Broer, Simone L.; Veening, Margreet A.; van Leeuwen, Jeanette; van Santen, Hanneke M.; van Dorp, Wendy; van den Heuvel-Eibrink, Marry M. (Elsevier, 2022-10)
    Infertility is a serious early, as well as late, effect of childhood cancer treatment. If addressed in a timely manner at diagnosis, fertility preservation measures can be taken, preferably before the start of cancer ...
  • Diagnostic pitfalls after COVID-19 vaccination in melanoma and breast cancer patients: A case series 
    de Bock, Ellen; Trumpi, Kari; Suijkerbuijk, Karijn P.M.; Vriens, Menno R.; Richir, Milan C. (Elsevier, 2022-04)
    Introduction: During the current Coronavirus Disease 2019 (COVID-19) pandemic, significant COVID-19 disease-reducing developments have been made, culminating in the COVID-19 vaccines. However, COVID-19 vaccines may complicate ...
  • Open multimodal iEEG-fMRI dataset from naturalistic stimulation with a short audiovisual film 
    Berezutskaya, Julia; Vansteensel, Mariska J.; Aarnoutse, Erik J.; Freudenburg, Zachary V.; Piantoni, Giovanni; Branco, Mariana P.; Ramsey, Nick F. (Nature Research, 2022-03-21)
    Intracranial human recordings are a valuable and rare resource of information about the brain. Making such data publicly available not only helps tackle reproducibility issues in science, it helps make more use of these ...
  • The relation between urinary sodium and potassium excretion and risk of cardiovascular events and mortality in patients with cardiovascular disease 
    Groenland, Eline H.; Vendeville, Jean Paul; Bots, Michiel L.; de Borst, Gert Jan; Nathoe, Hendrik M.; Ruigrok, Ynte M.; Blankestijn, Peter J.; Visseren, Frank L.J.; Spiering, Wilko (Public Library of Science, 2022-03)
    Background Most evidence on the relationship between sodium and potassium intake and cardiovascular disease originated from general population studies. This study aimed to evaluate the relation between estimated 24-hour ...
  • Long-term exposure to low ambient air pollution concentrations and mortality among 28 million people: results from seven large European cohorts within the ELAPSE project 
    Stafoggia, Massimo; Oftedal, Bente; Chen, Jie; Rodopoulou, Sophia; Renzi, Matteo; Atkinson, Richard W.; Bauwelinck, Mariska; Klompmaker, Jochem O.; Mehta, Amar; Vienneau, Danielle; Andersen, Zorana J.; Bellander, Tom; Brandt, Jørgen; Cesaroni, Giulia; de Hoogh, Kees; Fecht, Daniela; Gulliver, John; Hertel, Ole; Hoffmann, Barbara; Hvidtfeldt, Ulla A.; Jöckel, Karl Heinz; Jørgensen, Jeanette T.; Katsouyanni, Klea; Ketzel, Matthias; Kristoffersen, Doris Tove; Lager, Anton; Leander, Karin; Liu, Shuo; Ljungman, Petter L.S.; Nagel, Gabriele; Pershagen, Göran; Peters, Annette; Raaschou-Nielsen, Ole; Rizzuto, Debora; Schramm, Sara; Schwarze, Per E.; Severi, Gianluca; Sigsgaard, Torben; Strak, Maciek; van der Schouw, Yvonne T.; Verschuren, Monique; Weinmayr, Gudrun; Wolf, Kathrin; Zitt, Emanuel; Samoli, Evangelia; Forastiere, Francesco; Brunekreef, Bert; Hoek, Gerard; Janssen, Nicole A.H. (Elsevier, 2022-01)
    Background: Long-term exposure to ambient air pollution has been associated with premature mortality, but associations at concentrations lower than current annual limit values are uncertain. We analysed associations between ...
  • Sex Differences in Cognitive Functioning with Aging in the Netherlands 
    Nooyens, Astrid C.J.; Wijnhoven, Hanneke A.H.; Schaap, Laura S.; Sialino, Lena D.; Kok, Almar A.L.; Visser, Marjolein; Verschuren, W. M.Monique; Picavet, H. Susan J.; Van Oostrom, Sandra H. (S. Karger AG, 2022)
    INTRODUCTION: Dementia prevalence in older women is higher than that in men. The purpose of the present study was to investigate whether there is a female disadvantage in cognitive functioning at adult age and/or whether ...
  • Comparative study of two birth cohorts: did the explanatory role of behavioural, social and psychological factors in educational inequalities in mortality change over time? 
    Klokgieters, Silvia; Kok, Almar; Rijnhart, Judith; Visser, Marjolein; Broese van Groenou, Marjolein; Verschuren, Monique; Picavet, Susan; Huisman, Martijn (BMJ Publishing Group, 2022-03-08)
    OBJECTIVES: To investigate the contribution of behavioural, social and psychological factors to inequalities in mortality by educational level between birth cohorts. DESIGN: Cohort-sequential design. SETTING: Two ...
  • Challenging the silent temporomandibular joint paradigm in children with juvenile idiopathic arthritis 
    de Sonnaville, Willemijn F C; Steenks, Michel H; Speksnijder, Caroline M; Wulffraat, Nico M; Rosenberg, Antoine J W P (BioMed Central Ltd., 2022-12)
  • Validation of In Vivo Nodal Assessment of Solid Malignancies with USPIO-Enhanced MRI: A Workflow Protocol 
    Driessen, Daphne A.J.J.; de Gouw, Didi J.J.M.; Stijns, Rutger C.H.; Litjens, Geke; Israël, Bas; Philips, Bart W.J.; Hermans, John J.; Dijkema, Tim; Klarenbeek, Bastiaan R.; van der Post, Rachel S.; Nagtegaal, Iris D.; van Engen-Van Grunsven, Adriana C.H.; Brosens, Lodewijk A.A.; Veltien, Andor; Zámecnik, Patrik; Scheenen, Tom W.J. (Multidisciplinary Digital Publishing Institute (MDPI), 2022-03-07)
    Background: In various cancer types, the first step towards extended metastatic disease is the presence of lymph node metastases. Imaging methods with sufficient diagnostic accuracy are required to personalize treatment. ...
  • Analytical Validation of a Novel 6-Gene Signature for Prediction of Distant Recurrence in Estrogen Receptor-Positive, HER2-Negative, Early-Stage Breast Cancer 
    Loughman, Tony; Barron, Stephen; Wang, Chan-Ju Angel; Dynoodt, Peter; Fender, Bozena; Lopez-Ruiz, Cesar; Stapleton, Sharon; Fabre, Aurelie; Quinn, Cecily; Nodin, Bjorn; Jirström, Karin; Razmara, Fatemeh; O'Grady, Anthony; Baird, Anne-Marie; Gray, Steven G; Freixo, Ana; Moelans, Cathy B; van Diest, Paul J; Duffy, Michael J; O'Leary, Desmond; Crown, John; Bracken, Adrian P; Gallagher, William M (Oxford University Press, 2022-06-01)
    BACKGROUND: OncoMasTR is a recently developed multigene prognostic test for early-stage breast cancer. The test has been developed in a kit-based format for decentralized deployment in molecular pathology laboratories. The ...
  • Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy 
    de Jong, Vincent M T; Wang, Yuwei; Ter Hoeve, Natalie D; Opdam, Mark; Stathonikos, Nikolas; Jóźwiak, Katarzyna; Hauptmann, Michael; Cornelissen, Sten; Vreuls, Willem; Rosenberg, Efraim H; Koop, Esther A; Varga, Zsuzsanna; van Deurzen, Carolien H M; Mooyaart, Antien L; Córdoba, Alicia; Groen, Emma J; Bart, Joost; Willems, Stefan M; Zolota, Vasiliki; Wesseling, Jelle; Sapino, Anna; Chmielik, Ewa; Ryska, Ales; Broeks, Annegien; Voogd, Adri C; Loi, Sherene; Michiels, Stefan; Sonke, Gabe S; van der Wall, Elsken; Siesling, Sabine; van Diest, Paul J; Schmidt, Marjanka K; Kok, Marleen; Dackus, Gwen M H E; Salgado, Roberto; Linn, Sabine C (Lippincott Williams & Wilkins, 2022-07-20)
    PURPOSE: Triple-negative breast cancer (TNBC) is considered aggressive, and therefore, virtually all young patients with TNBC receive (neo)adjuvant chemotherapy. Increased stromal tumor-infiltrating lymphocytes (sTILs) ...
  • Age-dependent white matter disruptions after military traumatic brain injury: Multivariate analysis results from ENIGMA brain injury 
    Bouchard, Heather C.; Sun, Delin; Dennis, Emily L.; Newsome, Mary R.; Disner, Seth G.; Elman, Jeremy; Silva, Annelise; Velez, Carmen; Irimia, Andrei; Davenport, Nicholas D.; Sponheim, Scott R.; Franz, Carol E.; Kremen, William S.; Coleman, Michael J.; Williams, M. Wright; Geuze, Elbert; Koerte, Inga K.; Shenton, Martha E.; Adamson, Maheen M.; Coimbra, Raul; Grant, Gerald; Shutter, Lori; George, Mark S.; Zafonte, Ross D.; McAllister, Thomas W.; Stein, Murray B.; Thompson, Paul M.; Wilde, Elisabeth A.; Tate, David F.; Sotiras, Aristeidis; Morey, Rajendra A. (Wiley-Liss Inc., 2022-06-01)
    Mild Traumatic brain injury (mTBI) is a signature wound in military personnel, and repetitive mTBI has been linked to age-related neurogenerative disorders that affect white matter (WM) in the brain. However, findings of ...
  • Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study 
    Lassman, Andrew B; Sepúlveda-Sánchez, Juan Manuel; Cloughesy, Timothy; Gil-Gil, Miguel J; Puduvalli, Vinay K; Raizer, Jeffrey; De Vos, Filip Y F; Wen, Patrick Y; Butowski, Nicholas; Clement, Paul M J; Groves, Morris D; Belda-Iniesta, Cristobal; Giglio, Pierre; Soifer, Harris S; Rowsey, Steven; Xu, Cindy; Avogadri, Francesca; Wei, Ge; Moran, Susan; Roth, Patrick (American Association for Cancer Research Inc., 2022-06-01)
    Purpose: FGFR genomic alterations (amplification, mutations, and/or fusions) occur in ~8% of gliomas, particularly FGFR1 and FGFR3. We conducted a multicenter open-label, single-arm, phase II study of a selective FGFR1–3 ...
  • GATA-1 Defects in Diamond–Blackfan Anemia: Phenotypic Characterization Points to a Specific Subset of Disease 
    van Dooijeweert, Birgit; Kia, Sima Kheradmand; Dahl, Niklas; Fenneteau, Odile; Leguit, Roos; Nieuwenhuis, Edward; van Solinge, Wouter; van Wijk, Richard; Da Costa, Lydie; Bartels, Marije (Multidisciplinary Digital Publishing Institute (MDPI), 2022-03)
    Diamond–Blackfan anemia (DBA) is one of the inherited bone marrow failure syndromes marked by erythroid hypoplasia. Underlying variants in ribosomal protein (RP) genes account for 80% of cases, thereby classifying DBA as ...
  • Implementation of the Infection Risk Scan (IRIS) in nine hospitals in the Belgian-Dutch border region (i-4-1-Health project) 
    i-4-1-Health Study Group (BioMed Central Ltd., 2022-02-28)
    BACKGROUND: A tool, the Infection Risk Scan has been developed to measure the quality of infection control and antimicrobial use. This tool measures various patient-, ward- and care-related variables in a standardized way. ...
  • Tracing the origins of antibiotic resistance 
    Vandenbroucke-Grauls, Christina M J E; Kluytmans, Jan A J W (Nature Research, 2022-04)
  • Challenges in Von Hippel–Lindau’s disease: PRRT in patients on hemodialysis 
    Ayub, N.; Braat, A. J.A.T.; Timmers, H. J.L.M.; Lam, M. G.E.H.; van Leeuwaarde, R. S. (BioScientifica Ltd., 2022-03-01)
    Von Hippel–Lindau’s disease (VHL) is a hereditary tumor syndrome characterized by its prototype lesions, hemangioblastomas, and renal cell carcinomas. Treatment for renal cell carcinomas can ultimately result in long-term ...
  • Inhibitory control as a potential treatment target for obesity 
    de Klerk, M T; Smeets, Paul; la Fleur, S.E. (Taylor and Francis Ltd., 2023-05)
    OBJECTIVES: Strong reward responsiveness to food and insufficient inhibitory control are thought to be implicated in the development and maintenance of obesity. This narrative review addresses the role of inhibitory control ...
  • Advanced MRI in cerebral small vessel disease 
    van den Brink, Hilde; Doubal, Fergus N; Duering, Marco (SAGE Publications Ltd, 2023-01)
    Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review summarizes recent developments in advanced neuroimaging of cSVD with a focus on clinical and research applications. In the first ...