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Now showing items 11961-11980 of 40729

Carotid Artery Stenosis and Progression of Hemispheric Brain Atrophy: The SMART-MR Study

UCC-SMART Study Group (S. Karger AG, 2023-04-01)

INTRODUCTION: It has been hypothesized that carotid artery stenosis (CAS) may lead to greater atrophy of subserved brain regions; however, prospective studies on the impact of CAS on progression of hemispheric brain atrophy ...
Image quality and subject experience of quiet T1-weighted 7-T brain imaging using a silent gradient coil

Jacobs, Sarah M.; Versteeg, Edwin; van der Kolk, Anja G.; Visser, Leonie N.C.; Oliveira, Ícaro A.F.; van Maren, Emiel; Klomp, Dennis W.J.; Siero, Jeroen C.W. (Springer Science and Business Media Deutschland GmbH, 2022-08-31)

OBJECTIVES: Acoustic noise in magnetic resonance imaging (MRI) negatively impacts patients. We assessed a silent gradient coil switched at 20 kHz combined with a T 1-weighted magnetisation prepared rapid gradient-echo ...
Transfusion-induced red blood cell alloimmunisation is unhampered in elderly patients

Oud, Josine A; Evers, Dorothea; de Haas, Masja; de Vooght, Karen M K; van de Kerkhof, Daan; Som, Nel; Péquériaux, Nathalie C V; Hudig, Francisca; van der Bom, Johanna G; Zwaginga, Jaap Jan (Wiley-Blackwell, 2022-10)
Neurodevelopmental consequences of preterm punctate white matter lesions: a systematic review

de Bruijn, Clara Adriana Maria; Di Michele, Stefano; Tataranno, Maria Luisa; Ramenghi, Luca Antonio; Rossi, Andrea; Malova, Mariya; Benders, Manon; van den Hoogen, Agnes; Dudink, Jeroen (Lippincott Williams & Wilkins, 2023-05)

OBJECTIVES: To evaluate punctate white matter lesion (PWML) influence in preterm infants on the long-term neurodevelopmental outcome (NDO). METHODS: PubMed and EMBASE were searched from January 1, 2000, to May 31, 2021. ...
Oxidative Stress Biomarkers and Early Brain Activity in Extremely Preterm Infants: A Prospective Cohort Study

Coviello, Caterina; Perrone, Serafina; Buonocore, Giuseppe; Negro, Simona; Longini, Mariangela; Groenendaal, Floris; Vijlbrief, Daniel C; Dani, Carlo; Benders, Manon J N L; Tataranno, Maria Luisa (MDPI AG, 2022-09-12)

Early brain activity, measured using amplitude-integrated EEG (aEEG), is correlated with neurodevelopmental outcome in preterm newborns. F 2-isoprostanes (IPs) are early biomarkers predictive for brain damage. We aimed to ...
Correction: Slow recruitment in the HIMALAIA study: lessons for future clinical trials in patients with delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage based on feasibility data (Pilot and Feasibility Studies, (2022), 8, 1, (193), 10.1186/s40814-022-01155-4)

HIMALAIA Study Group (BioMed Central Ltd., 2022-09-22)

An amendment to this paper has been published and can be accessed via the original article.
Inhaled aviptadil for the possible treatment of COVID-19 in patients at high risk for ARDS: study protocol for a randomized, placebo-controlled, and multicenter trial

Boesing, Maria; Abig, Kristin; Brändle, Michael; Brutsche, Martin; Burri, Emanuel; Frye, Björn C; Giezendanner, Stéphanie; Grutters, Jan C; Haas, Philippe; Heisler, Justian; Jaun, Fabienne; Leuppi-Taegtmeyer, Anne B; Lüthi-Corridori, Giorgia; Müller-Quernheim, Joachim; Nüesch, Reto; Pohl, Wolfgang; Rassouli, Frank; Leuppi, Jörg D (BioMed Central, 2022-12)

BACKGROUND: Despite the fast establishment of new therapeutic agents in the management of COVID-19 and large-scale vaccination campaigns since the beginning of the SARS-CoV-2 pandemic in early 2020, severe disease courses ...
Efficacy and Safety of Tacrolimus as Treatment for Bleeding Caused by Hereditary Hemorrhagic Telangiectasia: An Open-Label, Pilot Study

Hessels, Josefien; Kroon, Steven; Boerman, Sanne; Nelissen, Rik C; Grutters, Jan C; Snijder, Repke J; Lebrin, Franck; Post, Marco C; Mummery, Christine L; Mager, Johannes-Jurgen (Multidisciplinary Digital Publishing Institute (MDPI), 2022-09-07)

Haploinsufficiency for Endoglin (ENG) and activin A receptor type II-like I ( ACVRL1/ALK1) lead to the formation of weak and abnormal vessels in hereditary hemorrhagic telangiectasia (HHT). These cause epistaxis (nosebleeds) ...
The importance of informal support and a listening ear: A narrative analysis of emotional conflict and support needs of siblings of children with a psychiatric disorder

Veldhuizen, Elien E.; Franssen, Gaston; Schothorst, Patricia F.; Scheepers, Floortje E. (SAGE Publications Ltd, 2023-10)

This study investigates the self-reported impact of children’s psychiatric disorders on their siblings and assesses what forms of support such children most value. We used a qualitative research design with open interviews ...
Impact of the COVID-19 pandemic on surgical care in the Netherlands

de Graaff, Michelle R.; Hogenbirk, Rianne N. M.; Janssen, Yester F.; Elfrink, Arthur K. E.; Liem, Ronald S. L.; Nienhuijs, Simon W.; de Vries, Jean-Paul P. M.; Elshof, Jan-Willem; Verdaasdonk, Emiel; Melenhorst, Jarno; van Westreenen, H. L.; Besselink, Marc G. H.; Ruurda, Jelle P.; Henegouwen, Mark I. van Berge; Klaase, Joost M.; den Dulk, Marcel; van Heijl, Mark; Hegeman, Johannes H.; Braun, Jerry; Voeten, Daan M.; Wurdemann, Franka S.; Warps, Anne-Loes K.; Alberga, Anna J.; Suurmeijer, J. Annelie; Akpinar, Erman O.; Wolfhagen, Nienke; van den Boom, Anne Loes; Bolster-van Eenennaam, Marieke J.; van Duijvendijk, Peter; Heineman, David J.; Wouters, Michel W. J. M.; Kruijff, Schelto (John Wiley & Sons Inc., 2022-12-01)

Background: The COVID-19 pandemic caused disruption of regular healthcare leading to reduced hospital attendances, repurposing of surgical facilities, and cancellation of cancer screening programmes. This study aimed to ...
Early Determinants of Adverse Motor Outcomes in Preschool Children with a Critical Congenital Heart Defect

Sprong, Maaike C A; Huijgen, Barbara C H; de Vries, Linda S; Talacua, Hanna; van Loon, Kim; Eijsermans, Rian M J C; Nijman, Joppe; Breur, Johannes M P J; van Brussel, Marco; Slieker, Martijn G (Multidisciplinary Digital Publishing Institute (MDPI), 2022-09-16)

Neurodevelopmental disabilities are common in infants with critical congenital heart disease (CCHD). A prospective, longitudinal cohort study was conducted to establish the prevalence and early determinants of adverse motor ...
Long-COVID and long-term cancer survivorship-Shared lessons and opportunities

Harada, Taku; Schmitz, Kathryn; Helsper, Charles W; Campbell, Grace; Nekhlyudov, Larissa (Wiley-Blackwell, 2022-11)

As of 2022, close to 90 million persons in the United States, 243 million persons in Europe and 585 million worldwide have been infected with the novel SARS-CoV-2 (COVID-19) virus and survived. Estimates vary but suggest ...
Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells

on behalf of the IciStem Consortium (Multidisciplinary Digital Publishing Institute (MDPI), 2022-09-17)

Allo-HSCT with CCR5Δ32/Δ32 donor cells is the only curative HIV-1 intervention. We investigated the impact of allo-HSCT on the viral reservoir in PBMCs and post-mortem tissue in two patients. IciS-05 and IciS-11 both ...
Requests for euthanasia or assisted suicide of people without (severe) illness

van den Berg, Vera E; Zomers, Margot L; van Thiel, Ghislaine Jmw; Leget, Carlo Jw; van Delden, Johannes Jm; van Wijngaarden, Els J (Elsevier Ireland Ltd, 2022-08)

BACKGROUND: Some people request euthanasia or assisted suicide (EAS) even though they are not (severely) ill. In the Netherlands the presence of sufficient medical ground for the suffering is a strict prerequisite for EAS. ...
Impact of phosphate binders on quality of life in dialysis patients: Results from the prospective Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes study

Colombijn, Julia M T; Vonk, Sanne; Cornelis, Tom; Boorsma, Siska; Krekels, Marielle M E; Abrahams, Alferso C; van Jaarsveld, Brigit C (Wiley-Blackwell, 2022-10)

BACKGROUND: Phosphate binders cause high pill burden for dialysis patients, complicate medication regimens, and have unpleasant taste and large size which may affect patients' quality of life. This study explores the ...
Mesodiencephalic junction GABAergic inputs are processed separately from motor cortical inputs in the basilar pons

Khalil, Ayoub J.; Mansvelder, Huibert D.; Witter, Laurens (Elsevier, 2022-07-15)

The basilar pontine nuclei (bPN) are known to receive excitatory input from the entire neocortex and constitute the main source of mossy fibers to the cerebellum. Various potential inhibitory afferents have been described, ...
Time-dependent uncertainty of critical care transitions in very old patients - lessons for time-limited trials

Beil, Michael; Flaatten, Hans; Guidet, Bertrand; Joskowicz, Leo; Jung, Christian; de Lange, Dylan; Leaver, Susannah; Fjølner, Jesper; Szczeklik, Wojciech; Sviri, Sigal; van Heerden, Peter Vernon (Elsevier, 2022-10)

PURPOSE: Prognostication for patients with critical conditions remains challenging, especially for very old individuals. Time-limited trials (TLT) are used to decrease prognostic uncertainty in the individual patient by ...
Performance of existing definitions and tests for the diagnosis of invasive aspergillosis in critically ill, non-neutropenic, adult patients: An update including COVID-19 data

Bassetti, Matteo; Zuccaro, Valentina; Asperges, Erika; Scudeller, Luigia; Giacobbe, Daniele Roberto; FUNDICU investigators (collaborators) (W.B. Saunders Ltd, 2022-11)
Poisoning in older adults: characterization of exposures reported to the Dutch Poisons Information Center

Rietjens, Saskia J; van der Heijden, Joyce E M; de Lange, Dylan W (Informa Healthcare, 2022-11)

Introduction: The annual number of patients > 65 years old about whom the Dutch Poisons Information Center (DPIC) was consulted has more than doubled in the last decade. We aimed to gain insight in the type and circumstances ...
Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

Abdominal Sepsis Study (AbSeS) group and the Trials Group of the European Society of Intensive Care Medicine (Springer-Verlag, 2022-11)

Purpose: To describe data on epidemiology, microbiology, clinical characteristics and outcome of adult patients admitted in the intensive care unit (ICU) with secondary peritonitis, with special emphasis on antimicrobial ...

Now showing items 11961-11980 of 40729