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Now showing items 11841-11860 of 40729

Development of the SAFETEA Scores for Predicting Risks of Complications of Preventive Endovascular or Microneurosurgical Intracranial Aneurysm Occlusion

Algra, Annemijn M.; Greving, Jacoba P.; De Winkel, Jordi; Kurtelius, Arttu; Laban, Kamil; Verbaan, Dagmar; Van Den Berg, René; Vandertop, William; Lindgren, Antti; Krings, Timo; Woo, Peter Y.M.; Wong, George K.C.; Roozenbeek, Bob; Van Es, Adriaan C.G.M.; Dammers, Ruben; Etminan, Nima; Boogaarts, Hieronymus; Van Doormaal, Tristan; Van Der Zwan, Albert; Van Der Schaaf, Irene C.; Rinkel, Gabriël J.E.; Vergouwen, Mervyn D.I. (Lippincott Williams & Wilkins, 2022-10-18)

Background and ObjectivesPreventive unruptured intracranial aneurysm (UIA) occlusion can reduce the risk of subarachnoid hemorrhage, but both endovascular and microneurosurgical treatment carry a risk of serious complications. ...
Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage

Gaastra, Ben; Duncan, Poppy; Bakker, Mark K.; Hostettler, Isabel C.; Alg, Varinder S.; Houlden, Henry; Ruigrok, Ynte M.; Galea, Ian; Tapper, Will; Werring, David; Bulters, Diederik (Wiley-Blackwell, 2023-01)

Background and purpose: Nuclear factor erythroid 2-related factor 2 (NRF2; encoded by the NFE2L2 gene) has been implicated in outcome following aneurysmal subarachnoid haemorrhage (aSAH) through its activity as a regulator ...
Low risk of local recurrence after a successful en bloc Endoscopic Submucosal Dissection for non-invasive colorectal lesions with positive horizontal resection margins(R-ESD study)

Haasnoot, Krijn; Baldaque-Silva, Francisco; Koch, Arjun Dave; Figueiredo Ferreira, Mariana; Santos-Antunes, João; Dias, Emanuel; Omae, Masami; van Tilburg, Laurelle; Dang, Hao; Lemmers, Arnaud; Boonstra, Jurjen J; Moons, Leon Mg (Georg Thieme Verlag, 2023-03-01)

BACKGROUND : During endoscopic submucosal dissection (ESD), the normal mucosa is cut under constant optical control. We studied whether a positive horizontal resection margin after a complete en bloc ESD predicts local ...
A Uremic Pig Model for Peritoneal Dialysis

de Vries, Joost C.; van Gelder, Maaike K.; Monninkhof, Anneke S.; Ahmed, Sabbir; Hazenbrink, Diënty H.M.; Nguyen, Tri Q.; de Kort, Gèrard A.P.; Vonken, Evert Jan P.A.; Vaessen, Koen R.D.; Joles, Jaap A.; Verhaar, Marianne C.; Gerritsen, Karin G.F. (Multidisciplinary Digital Publishing Institute (MDPI), 2022-09-14)

With increasing interest in home dialysis, there is a need for a translational uremic large animal model to evaluate technical innovations in peritoneal dialysis (PD). To this end, we developed a porcine model with kidney ...
Improved sensitivity and precision in multicentre diffusion MRI network analysis using thresholding and harmonization

de Brito Robalo, Bruno M; de Luca, Alberto; Chen, Christopher; Dewenter, Anna; Duering, Marco; Hilal, Saima; Koek, Huiberdina L; Kopczak, Anna; Lam, Bonnie Yin Ka; Leemans, Alexander; Mok, Vincent; Onkenhout, Laurien P; van den Brink, Hilde; Biessels, Geert Jan (Elsevier, 2022-10-11)

PURPOSE: To investigate if network thresholding and raw data harmonization improve consistency of diffusion MRI (dMRI)-based brain networks while also increasing precision and sensitivity to detect disease effects in ...
Immunosuppressive Therapies in Ear, Nose, and Throat Involvement in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Results From a Multicenter Retrospective Cohort Study

Krol, Roline M; Schaap, Caroline M; Welsing, Paco M J; Klaasen, Ruth; Remmelts, Hilde H F; Hagen, E Christiaan; Heijstek, Marloes W; Spierings, Julia (Journal of Rheumatology, 2023-03-01)

OBJECTIVE: The aim of this study was to evaluate the response of ear, nose, and throat (ENT) symptoms to different immunosuppressive therapies in patients with antineutrophil cytoplasmic antibody-associated vasculitis ...
TOFA-PREDICT study protocol: a stratification trial to determine key immunological factors predicting tofacitinib efficacy and drug-free remission in psoriatic arthritis (PsA)

TOFA-PREDICT author group (BMJ Publishing Group, 2022-10-10)

INTRODUCTION: Psoriatic arthritis (PsA) is a chronic, inflammatory, musculoskeletal disease that affects up to 30% of patients with psoriasis. Current challenges in clinical care and research include personalised treatment, ...
Carfilzomib, Pomalidomide, and Dexamethasone As Second-line Therapy for Lenalidomide-refractory Multiple Myeloma

Sonneveld, Pieter; Zweegman, Sonja; Cavo, Michele; Nasserinejad, Kazem; Broijl, Annemiek; Troia, Rosella; Pour, Ludek; Croockewit, Sandra; Corradini, Paolo; Patriarca, Francesca; Wu, Kalung; Droogendijk, Jolanda; Bos, Gerard; Hajek, Roman; Teresa Petrucci, Maria; Ypma, Paula; Zojer, Nicholas; Minnema, Monique C; Boccadoro, Mario (Wolters Kluwer Health, 2022-10)

This phase 2 trial investigated reinduction with carfilzomib, pomalidomide, and dexamethasone (KPd) and continuous pomalidomide/dexamethasone in patients at first progression during lenalidomide maintenance. The second ...
Iberdomide plus dexamethasone in heavily pretreated late-line relapsed or refractory multiple myeloma (CC-220-MM-001): a multicentre, multicohort, open-label, phase 1/2 trial

Lonial, Sagar; Popat, Rakesh; Hulin, Cyrille; Jagannath, Sundar; Oriol, Albert; Richardson, Paul G; Facon, Thierry; Weisel, Katja; Larsen, Jeremy T; Minnema, Monique C; Abdallah, Al-Ola; Badros, Ashraf Z; Knop, Stefan; Stadtmauer, Edward A; Cheng, Yiming; Amatangelo, Michael; Chen, Min; Nguyen, Tuong Vi; Amin, Alpesh; Peluso, Teresa; van de Donk, Niels W C J (Lancet Publishing Group, 2022-11)

BACKGROUND: Iberdomide is a novel cereblon E3 ligase modulator with enhanced tumouricidal and immune-stimulatory effects compared with immunomodulatory drugs. In preclinical myeloma models, iberdomide has shown synergy ...
State-of-the-Art Multimodality Imaging in Sudden Cardiac Arrest with Focus on Idiopathic Ventricular Fibrillation: A Review

Verheul, Lisa M.; Groeneveld, Sanne A.; Kirkels, Feddo P.; Volders, Paul G.A.; Teske, Arco J.; Cramer, Maarten J.; Guglielmo, Marco; Hassink, Rutger J. (Multidisciplinary Digital Publishing Institute (MDPI), 2022-08-10)

Idiopathic ventricular fibrillation is a rare cause of sudden cardiac arrest and a diagnosis by exclusion. Unraveling the mechanism of ventricular fibrillation is important for targeted management, and potentially for ...
New Inhibitors in the Ageing Population: A Retrospective, Observational, Cohort Study of New Inhibitors in Older People with Hemophilia

Astermark, Jan; Ay, Cihan; Carvalho, Manuela; D'Oiron, Roseline; Moerloose, Philippe De; Dolan, Gerard; Fontana, Pierre; Hermans, Cedric; Holme, Pål Andre; Katsarou, Olga; Kenet, Gili; Klamroth, Robert; Mancuso, Maria Elisa; Marquardt, Natascha; Núñez, Ramiro; Pabinger, Ingrid; Tait, Robert; Valk, Paul van der (Schattauer GmbH, 2022-06-01)

INTRODUCTION: A second peak of inhibitors has been reported in patients with severe hemophilia A (HA) aged >50 years in the United Kingdom. The reason for this suggested breakdown of tolerance in the aging population is ...
Rates and Predictors of Treatment Failure in Staphylococcus aureus Prosthetic Joint Infections According to Different Management Strategies: A Multinational Cohort Study—The ARTHR-IS Study Group

The ARTHR-IS Group (Springer Healthcare, 2022-12)

Introduction: Guidelines have improved the management of prosthetic joint infections (PJI). However, it is necessary to reassess the incidence and risk factors for treatment failure (TF) of Staphylococcus aureus PJI (SA-PJI) ...
Vitamin D status in children with a psychiatric diagnosis, autism spectrum disorders, or internalizing disorders

Muskens, Jet; Klip, Helen; Zinkstok, Janneke R.; van Dongen-Boomsma, Martine; Staal, Wouter G. (Frontiers Research Foundation, 2022-09-14)

Background and objective: Multiple studies suggest that children with Autism Spectrum Disorders (ASD) have significantly lower vitamin D3 levels than typically developing children. However, whether vitamin D3 deficiency ...
Genetic determinants associated with response to clozapine in schizophrenia: An umbrella review

Van Der Horst, Marte Z.; Papadimitriou, Georgia; Luykx, Jurjen J. (Lippincott Williams & Wilkins, 2022-10-01)

Objective Clozapine response varies widely from person to person, which may be due to inter-individual genetic variability. This umbrella review aims to summarize the current evidence on associations between pharmacodynamic ...
Neuroprotective therapies in the NICU in term infants: present and future

Newborn Brain Society Guidelines and Publications Committee (Lippincott Williams & Wilkins, 2023-06)

Abstract: Outcomes of neonatal encephalopathy (NE) have improved since the widespread implementation of therapeutic hypothermia (TH) in high-resource settings. While TH for NE in term and near-term infants has proven ...
Delayed Surgical Closure of the Patent Ductus Arteriosus: does the Brain pay the Price?

Lemmers, Petra; Vijlbrief, Daniel; Benders, Manon; Alderliesten, Thomas; Veldhuis, Moniek; Baerts, Wim; Koopman-Esseboom, Corine; Groenendaal, Floris; van Bel, Frank (Mosby Inc., 2023-03)

Objective: To investigate the relation between duration of hemodynamically significant patent ductus arteriosus (PDA), cerebral oxygenation, magnetic resonance imaging–determined brain growth, and 2-year neurodevelopmental ...
Screening, diagnosis and follow-up of Brugada syndrome in children: a Dutch expert consensus statement

Peltenburg, P J; Hoedemaekers, Y M; Clur, S A B; Blom, N A; Blank, A C; Boesaard, E P; Frerich, S; van den Heuvel, F; Wilde, A A M; Kammeraad, J A E (Bohn Stafleu van Loghum, 2023-04)

Brugada syndrome (BrS) is a rare inherited arrhythmia syndrome. Affected children may experience life-threatening symptoms, mainly during fever. The percentage of SCN5A variant carriers in children is higher than in adults. ...
Human neutrophil kinetics: a call to revisit old evidence

Koenderman, Leo; Tesselaar, Kiki; Vrisekoop, Nienke (Elsevier Limited, 2022-11)

The half-life of human neutrophils is still controversial, with estimates ranging from 7–9 h to 3.75 days. This debate should be settled to understand neutrophil production in the bone marrow (BM) and the potential and ...
Low-grade carotid artery stenosis is associated with progression of brain atrophy and cognitive decline. The SMART-MR study

UCC-SMART Study Group (SAGE Publications Inc., 2023-02)

Asymptomatic low-grade carotid artery stenosis (LGCS) is a common finding in patients with manifest arterial disease, however its relationship with brain MRI changes and cognitive decline is unclear. We included 902 patients ...
Food processing and risk of Crohn's disease and ulcerative colitis: A European Prospective Cohort Study

Meyer, Antoine; Dong, Catherine; Casagrande, Corinne; Chan, Simon; Huybrechts, Inge; Nicolas, Geneviève; Rauber, Fernanda; Levy, Renata Bertazzi; Millett, Christopher; Oldenburg, Bas; Weiderpass, Elisabete; Heath, Alicia K; Tong, Tammy Yn; Tjønneland, Anne; Kyrø, Cecilie; Kaaks, Rudolf; Katzke, Verena A; Bergman, Manuela M; Palli, Domenico; Masala, Giovanna; Tumino, Rosario; Sacerdote, Carlotta; Colorado-Yohar, Sandra M; Sánchez, Maria-Jose; Grip, Olof; Lindgren, Stefan; Luben, Robert; Gunter, Marc J; Mahamat-Saleh, Yahya; Boutron-Ruault, Marie-Christine; Carbonnel, Franck (W.B. Saunders, 2023-06)

BACKGROUND & AIMS: Industrial foods have been associated with increased risks of several chronic conditions. We investigated the relationship between the degree of food processing and risks of Crohn's disease (CD) and ...

Now showing items 11841-11860 of 40729