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The risk of delayed spinal cord injury in pediatric spinal deformity surgery

Rutges, J. P.H.J.; Renkens, J. J.M.; Kempen, D. H.R.; Faber, C.; Stadhouder, A.; Kruyt, M. C.; Mostert, A.; Horsting, P. P.; de Klerk, L. W.L.; de Kleuver, M.; Castelein, R. M.; Schlösser, T. P.C. (Elsevier, 2023-05)

Delayed spinal cord injury (SCI) hours or days after surgery, with uneventful monitoring and initial normal postoperative neurological examination, is a rare complication. Based on anecdotal evidence, the risk of delayed ...
Indicators of questionable research practices were identified in 163,129 randomized controlled trials

Damen, Johanna A; Heus, Pauline; Lamberink, Herm J; Tijdink, Joeri K; Bouter, Lex; Glasziou, Paul; Moher, David; Otte, Willem M; Vinkers, Christiaan H; Hooft, Lotty (Elsevier, 2023-02)

Objectives: To explore indicators of the following questionable research practices (QRPs) in randomized controlled trials (RCTs): (1) risk of bias in four domains (random sequence generation, allocation concealment, blinding ...
Topology of diffusion changes in corpus callosum in Alzheimer's disease: An exploratory case-control study

Kumar, Sumeet; De Luca, Alberto; Leemans, Alexander; Saffari, Seyed Ehsan; Hartono, Septian; Zailan, Fatin Zahra; Ng, Kok Pin; Kandiah, Nagaendran (Frontiers Media S. A., 2022-11-30)

AIM: This study aims to assess the integrity of white matter in various segments of the corpus callosum in Alzheimer's disease (AD) by using metrics derived from diffusion tensor imaging (DTI), diffusion kurtosis imaging ...
Exercise therapy for fatigue in multiple sclerosis

Heine, Martin; Rietberg, Marc B.; Amaral Gomes, Elvira; Evenhuis, Ernst; Beckerman, Heleen; van de Port, Ingrid; de Groot, Vincent; Kwakkel, Gert; van Wegen, Erwin E.H. (John Wiley & Sons Inc., 2022-12-12)

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. Primary objectives The primary objectives of this review are as follows. 1.1 To determine the immediate (i.e. postintervention; ...
Altered fibrin network structure and fibrinolysis in intensive care unit patients with COVID-19, not entirely explaining the increased risk of thrombosis

de Vries, Judith J; Visser, Chantal; Geers, Lotte; Slotman, Johan A; van Kleef, Nadine D; Maas, Coen; Bax, Hannelore I; Miedema, Jelle R; van Gorp, Eric C M; Goeijenbier, Marco; van den Akker, Johannes P C; Endeman, Henrik; Rijken, Dingeman C; Kruip, Marieke J H A; de Maat, Moniek P M (Wiley-Blackwell, 2022-06)

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 infection is associated with an increased incidence of thrombosis. OBJECTIVES: By studying the fibrin network structure of coronavirus disease 2019 (COVID-19) ...
Nanomedicine platform for targeting activated neutrophils and neutrophil-platelet complexes using an α1-antitrypsin-derived peptide motif

Cruz, Michelle A; Bohinc, Dillon; Andraska, Elizabeth A; Alvikas, Jurgis; Raghunathan, Shruti; Masters, Nicole A; van Kleef, Nadine D; Bane, Kara L; Hart, Kathryn; Medrow, Kathryn; Sun, Michael; Liu, Haitao; Haldeman, Shannon; Banerjee, Ankush; Lessieur, Emma M; Hageman, Kara; Gandhi, Agharnan; de la Fuente, Maria; Nieman, Marvin T; Kern, Timothy S; Maas, Coen; de Maat, Steven; Neeves, Keith B; Neal, Matthew D; Sen Gupta, Anirban; Stavrou, Evi X (Nature Publishing Group, 2022-09)

Targeted drug delivery to disease-associated activated neutrophils can provide novel therapeutic opportunities while avoiding systemic effects on immune functions. We created a nanomedicine platform that uniquely utilizes ...
Factor XII Explored with AlphaFold - Opportunities for Selective Drug Development

Frunt, Rowan; El Otmani, Hinde; Gibril Kaira, Bubacarr; de Maat, Steven; Maas, Coen (Schattauer GmbH, 2023-02-07)

Medical device associated thrombosis is an important clinical problem. This type of thrombosis can result from Factor XII (FXII) binding to non-natural surface materials and subsequent activation of the contact pathway. ...
Erratum: Antihistone properties of C1 esterase inhibitor protect against lung injury (Am J Respir Crit Care Med (2017) 196 (186–199) DOI: 10.1164/rccm.201604-0712OC)

Wygrecka, Malgorzata; Wujak, Lukasz; Markart, Philipp; Kosanovic, Djuro; Müller-Redetzky, Holger C; Witzenrath, Martin; Henneke, Ingrid; Schermuly, Ralph T; Seeger, Werner; Schaefer, Liliana; Kwapiszewska, Grazyna; Marsh, Leigh M; Baal, Nelli; Hackstein, Holger; Maat, Steven de; Maas, Coen (American Thoracic Society, 2022-11-01)

The authors wish to inform the readers that there is an error in their article published in the July 15, 2017 issue of AJRCCM (1). It was brought to their attention that they had inadvertently duplicated a representative ...
Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood

Konrath, Sandra; Mailer, Reiner K; Beerens, Manu; Englert, Hanna; Frye, Maike; Kuta, Piotr; Preston, Roger J S; Maas, Coen; Butler, Lynn M; Roest, Mark; de Laat, Bas; Renné, Thomas (Frontiers Media S. A., 2022-11-28)

Calibrated Automated Thrombography (CAT) is a versatile and sensitive method for analyzing coagulation reactions culminating in thrombin generation (TG). Here, we present a CAT method for analyzing TG in murine whole blood ...
Fetal movement trials: Where is the evidence in settings with a high burden of stillbirths?

Housseine, Natasha; Browne, Joyce; Maaløe, Nanna; Dmello, Brenda Sequeira; Ali, Sam; Abeid, Muzdalifat; Meguid, Tarek; Rijken, Marcus J; Kidanto, Hussein (Wiley-Blackwell, 2023-02)
Effects of race and ethnicity on perinatal outcomes in high-income and upper-middle-income countries: an individual participant data meta-analysis of 2 198 655 pregnancies

Sheikh, Jameela; Allotey, John; Kew, Tania; Fernández-Félix, Borja M; Zamora, Javier; Khalil, Asma; Thangaratinam, Shakila; IPPIC Collaborative Network (Elsevier, 2022-12-10)

BACKGROUND: Existing evidence on the effects of race and ethnicity on pregnancy outcomes is restricted to individual studies done within specific countries and health systems. We aimed to assess the impact of race and ...
Maternal near-miss and mortality associated with hypertensive disorders of pregnancy remote from term: a multicenter observational study in Ghana

Severe Preeclampsia adverse Outcome Triage (SPOT) studies consortium (Elsevier, 2022-05)

BACKGROUND: Maternal death rates remain high in many low- and middle-income countries. Hypertensive disorders of pregnancy account for 18% of maternal mortality in Ghana. The maternal near-miss approach was designed to ...
Health professionals' perspectives on clinical challenges in managing hypertensive disorders of pregnancy and recommendations for improving care: A multi-center qualitative study

Adu-Bonsaffoh, Kwame; Tamma, Evelyn; Nwameme, Adanna Uloaku; Browne, Joyce L (Frontiers Media S. A., 2022-11-10)

BACKGROUND: Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal mortality and morbidity globally despite the intensive international effort to improving maternal care. Substandard clinical care has ...
Development and validation of a prediction rule for patients suspected of acute coronary syndrome in primary care: a cross-sectional study

Wouters, Loes T. C. M.; Zwart, Dorien L. M.; Erkelens, Daphne C. A.; Adriaansen, Elisabeth J. M.; den Ruijter, Hester M.; De Groot, Esther; Damoiseaux, Roger A. M. J.; Hoes, Arno W.; van Smeden, Maarten; Rutten, Frans H. (BMJ Publishing Group, 2022-10-05)

Objective To develop and validate a symptom-based prediction rule for early recognition of acute coronary syndrome (ACS) in patients with acute chest discomfort who call out-of-hours services for primary care (OHS-PC). ...
Missed Acute Coronary Syndrome During Telephone Triage at Out-of-Hours Primary Care: Lessons From A Case-Control Study

Erkelens, Daphne C.; Rutten, Frans H.; Wouters, Loes T.; Kirkels, Harmke G.; Poldervaart, Judith M.; de Groot, Esther; Damoiseaux, Roger A.; Hoes, Arno W.; Zwart, Dorien L. (Lippincott Williams & Wilkins, 2022-01-01)

OBJECTIVES: Serious adverse events at out-of-hours services in primary care (OHS-PC) are rare, and the most often concern is missed acute coronary syndrome (ACS). Previous studies on serious adverse events mainly concern ...
Cancer detection during the COVID-19 pandemic—Experiences in primary care and recommendations for the future

COVID and Cancer-NL consortium (Wiley-Blackwell Publishing Ltd, 2023-03-14)

Background: To describe general practitioners (GPs) experiences with the impact COVID-19 on the duration of cancer detection. Methods: Cross-sectional survey study among Dutch GPs. Results: Fifty-eight GPs participated. ...
Improved Selectivity in 7 T Digit Mapping Using VASO-CBV

de Oliveira, Ícaro A.F.; Siero, Jeroen C.W.; Dumoulin, Serge O.; van der Zwaag, Wietske (Kluwer Academic/Human Sciences Press Inc., 2023-01)

Functional magnetic resonance imaging (fMRI) at Ultra-high field (UHF, ≥ 7 T) benefits from significant gains in the BOLD contrast-to-noise ratio (CNR) and temporal signal-to-noise ratio (tSNR) compared to conventional ...
[18F]mFBG PET/CT imaging outperforms MRI and [68 Ga]Ga-DOTA-TOC PET/CT in identifying recurrence pheochromocytoma.

Suurd, Diederik P.D.; Poot, Alex J.; van Leeuwaarde, Rachel S.; Windhorst, Albert D.; Vriens, Menno R.; de Keizer, Bart (Springer-Verlag, 2023-04)
Constipation and cystic fibrosis. Slow movement

van der Doef, H. P.J.; Houwen, R. H.J. (Elsevier, 2022-05)
Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial

Thompson, Richard J; Arnell, Henrik; Artan, Reha; Baumann, Ulrich; Calvo, Pier Luigi; Czubkowski, Piotr; Dalgic, Buket; D'Antiga, Lorenzo; Durmaz, Özlem; Fischler, Björn; Gonzalès, Emmanuel; Grammatikopoulos, Tassos; Gupte, Girish; Hardikar, Winita; Houwen, Roderick H J; Kamath, Binita M; Karpen, Saul J; Kjems, Lise; Lacaille, Florence; Lachaux, Alain; Lainka, Elke; Mack, Cara L; Mattsson, Jan P; McKiernan, Patrick; Özen, Hasan; Rajwal, Sanjay R; Roquelaure, Bertrand; Shagrani, Mohammad; Shteyer, Eyal; Soufi, Nisreen; Sturm, Ekkehard; Tessier, Mary Elizabeth; Verkade, Henkjan J; Horn, Patrick (Elsevier Limited, 2022-09)

BACKGROUND: Progressive familial intrahepatic cholestasis (PFIC) is a group of inherited paediatric liver diseases resulting from mutations in genes that impact bile secretion. We aimed to evaluate the effects of odevixibat, ...

Now showing items 11101-11120 of 40729