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Now showing items 10481-10500 of 40729

Evidence for a genetic contribution to the ossification of spinal ligaments in Ossification of Posterior Longitudinal Ligament and Diffuse idiopathic skeletal hyperostosis: A narrative review

Couto, Ana Rita; Parreira, Bruna; Power, Deborah M.; Pinheiro, Luís; Madruga Dias, João; Novofastovski, Irina; Eshed, Iris; Sarzi-Puttini, Piercarlo; Pappone, Nicola; Atzeni, Fabiola; Verlaan, Jorrit Jan; Kuperus, Jonneke; Bieber, Amir; Ambrosino, Pasquale; Kiefer, David; Khan, Muhammad Asim; Mader, Reuven; Baraliakos, Xenofon; Bruges-Armas, Jácome (Frontiers Media S. A., 2022-10-07)

Diffuse Idiopathic Skeletal Hyperostosis (DISH) and Ossification of the Posterior Longitudinal Ligament (OPLL) are common disorders characterized by the ossification of spinal ligaments. The cause for this ossification is ...
Prevalence of- and factors associated with limited health literacy in spine patients

Lans, Amanda; Bales, John R.; Tobert, Daniel G.; Rossi, Laura P.; Verlaan, Jorrit Jan; Schwab, Joseph H. (Elsevier, 2023-03)

Background: Limited health literacy exacerbates health inequity and has serious implications for patient care. It hinders successful communication and comprehension of relevant health information, which can lead to suboptimal ...
Reliability of self-reported health literacy screening in spine patients

Lans, Amanda; Bales, John R.; Fourman, Mitchell S.; Tobert, Daniel G.; Verlaan, Jorrit Jan; Schwab, Joseph H. (Elsevier, 2023-05)

BACKGROUND CONTEXT: Limited health literacy has previously been associated with increased health care utilization, worse general health status and self-reported health, and increased mortality. Identifying and accommodating ...
The role of tumour biological factors in technical anatomical resectability assessment of colorectal liver metastases following induction systemic treatment: An analysis of the Dutch CAIRO5 trial

Dutch Colorectal Cancer Group Liver Expert Panel (Elsevier Limited, 2023-04)

Background: Large inter-surgeon variability exists in technical anatomical resectability assessment of colorectal cancer liver-only metastases (CRLM) following induction systemic therapy. We evaluated the role of tumour ...
Programs to Prepare Siblings for Future Roles to Support Their Brother or Sister with a Neurodevelopmental Disability: a Scoping Review

Nguyen, Linda; Bootsma, Jael; Ketelaar, Marjolijn; Di Rezze, Briano; Jack, Susan M; Gorter, Jan Willem (Springer Nature Switzerland AG, 2023)

Purpose of Review: To identify and map the characteristics and outcomes of programs designed to prepare siblings for their future roles with their sibling with a neurodevelopmental disability. Recent Findings: Existing ...
In vivo phosphorus magnetic resonance spectroscopic imaging of the whole human liver at 7 T using a phosphorus whole-body transmit coil and 16-channel receive array: Repeatability and effects of principal component analysis-based denoising

van den Wildenberg, Lieke; Gursan, Ayhan; Seelen, Leonard W.F.; van der Velden, Tijl A.; Gosselink, Mark W.J.M.; Froeling, Martijn; van der Kemp, Wybe J.M.; Klomp, Dennis W.J.; Prompers, Jeanine J. (John Wiley & Sons Inc., 2023-05)

Quantitative three-dimensional (3D) imaging of phosphorus (31P) metabolites is potentially a promising technique with which to assess the progression of liver disease and monitor therapy response. However, 31P magnetic ...
A Systematic Review of Chest Imaging Findings in Long COVID Patients

P4O2 Consortium (MDPI Multidisciplinary Digital Publishing Institute, 2023-02-01)

Long COVID is the persistence of one or more COVID-19 symptoms after the initial viral infection, and there is evidence supporting its association with lung damage. In this systematic review, we provide an overview of lung ...
Towards Standardisation of a Diffuse Midline Glioma Patient-Derived Xenograft Mouse Model Based on Suspension Matrices for Preclinical Research

't Hart, Elvin; Bianco, John; Besse, Helena C; Chin Joe Kie, Lois A; Cornet, Lesley; Eikelenboom, Kimberly L; van den Broek, Thijs J M; Derieppe, Marc; Su, Yan; Hoving, Eelco W; Ries, Mario G; van Vuurden, Dannis G (MDPI AG, 2023-02-11)

Diffuse midline glioma (DMG) is an aggressive brain tumour with high mortality and limited clinical therapeutic options. Although in vitro research has shown the effectiveness of medication, successful translation to the ...
In Regard to Dennstädt et al

Raaijmakers, Cornelis P J; Roesink, Judith M; Houweling, Anette C; Braam, Petra M; Dijkema, Tim (Elsevier, 2023-03-15)
Recurrence characteristics after focal salvage HDR brachytherapy in prostate cancer

Rasing, Marnix J.A.; Peters, Max; van Son, Marieke; Moerland, Marinus A.; Eppinga, Wietse; van de Pol, Sandrine M.G.; Noteboom, Juus; Lagendijk, Jan; van der Voort van Zyp, Jochem R.N. (Elsevier Ireland Ltd, 2023-03)

Background and purpose: Radiorecurrent prostate cancer is often confined to the prostate, predominantly near the index lesion. The purpose of this study was to look at recurrence characteristics in patients treated with ...
STereotactic Arrhythmia Radioablation: current status of the art. The old world and the new world connected

Trombetta, Mark; Verhoeff, Joost (Cambridge University Press, 2023-01-06)
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

van der Velden, Jolanda; Asselbergs, Folkert W.; Bakkers, Jeroen; Batkai, Sandor; Bertrand, Luc; Bezzina, Connie R.; Bot, Ilze; Brundel, Bianca J.J.M.; Carrier, Lucie; Chamuleau, Steven; Ciccarelli, Michele; Dawson, Dana; Davidson, Sean M.; Dendorfer, Andreas; Duncker, Dirk J.; Eschenhagen, Thomas; Fabritz, Larissa; Falcão-Pires, Ines; Ferdinandy, Péter; Giacca, Mauro; Girao, Henrique; Gollmann-Tepeköylü, Can; Gyongyosi, Mariann; Guzik, Tomasz J.; Hamdani, Nazha; Heymans, Stephane; Hilfiker, Andres; Hilfiker-Kleiner, Denise; Hoekstra, Alfons G.; Hulot, Jean Sébastien; Kuster, Diederik W.D.; van Laake, Linda W.; Lecour, Sandrine; Leiner, Tim; Linke, Wolfgang A.; Lumens, Joost; Lutgens, Esther; Madonna, Rosalinda; Maegdefessel, Lars; Mayr, Manuel; van der Meer, Peter; Passier, Robert; Perbellini, Filippo; Perrino, Cinzia; Pesce, Maurizio; Priori, Silvia; Remme, Carol Ann; Rosenhahn, Bodo; Schotten, Ulrich; Schulz, Rainer; Sipido, Karin R.; Sluijter, Joost P.G.; van Steenbeek, Frank; Steffens, Sabine; Terracciano, Cesare M.; Tocchetti, Carlo Gabriele; Vlasman, Patricia; Yeung, Kak Khee; Zacchigna, Serena; Zwaagman, Dayenne; Thum, Thomas (Oxford University Press, 2022)

Cardiovascular diseases represent a major cause of morbidity and mortality, necessitating research to improve diagnostics, and to discover and test novel preventive and curative therapies, all of which warrant experimental ...
Evaluation and manipulation of tissue and cellular distribution of cardiac progenitor cell-derived extracellular vesicles

Roefs, Marieke T.; Heusermann, Wolf; Brans, Maike A.D.; Snijders Blok, Christian; Lei, Zhiyong; Vader, Pieter; Sluijter, Joost P.G. (Frontiers Media S. A., 2022-11-24)

Cardiac progenitor cell-derived extracellular vesicles (CPC-EVs) have been successfully applied via different delivery routes for treating post-myocardial infarction injury in several preclinical models. Hence, understanding ...
NLRP3-Inflammasome Inhibition with IZD334 Does Not Reduce Cardiac Damage in a Pig Model of Myocardial Infarction

Silvis, Max J.M.; Demkes, Evelyne J.; Timmers, Leo; Arslan, Fatih; de Jager, Saskia C.A.; Sluijter, Joost P.G.; Mosterd, Arend; de Kleijn, Dominique P.V.; Bosch, Lena; van Hout, Gerardus P.J. (MDPI AG, 2022-12)

NLRP3-inflammasome-mediated signaling is thought to significantly contribute to the extent of myocardial damage after myocardial infarction (MI). The purpose of this study was to investigate the effects of the NLRP3-inflammasome ...
Elevated Plasma Immunoglobulin Levels Prior to Heart Transplantation Are Associated with Poor Post-Transplantation Survival

van den Hoogen, Patricia; Huibers, Manon M.H.; van den Dolder, Floor W.; de Weger, Roel; Siera-de Koning, Erica; Oerlemans, Marish I.F.; de Jonge, Nicolaas; van Laake, Linda W.; Doevendans, Pieter A.; Sluijter, Joost P.G.; Vink, Aryan; de Jager, Saskia C.A. (MDPI Multidisciplinary Digital Publishing Institute, 2023-01)

Cardiac allograft vasculopathy (CAV) and antibody-mediated rejection are immune-mediated, long-term complications that jeopardize graft survival after heart transplantation (HTx). Interestingly, increased plasma levels of ...
Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases

Li, Guoping; Chen, Tianji; Dahlman, James; Eniola-Adefeso, Lola; Ghiran, Ionita C.; Kurre, Peter; Lam, Wilbur A.; Lang, Jennifer K.; Marbán, Eduardo; Martín, Pilar; Momma, Stefan; Moos, Malcolm; Nelson, Deborah J.; Raffai, Robert L.; Ren, Xi; Sluijter, Joost P.G.; Stott, Shannon L.; Vunjak-Novakovic, Gordana; Walker, Nykia D.; Wang, Zhenjia; Witwer, Kenneth W.; Yang, Phillip C.; Lundberg, Martha S.; Ochocinska, Margaret J.; Wong, Renee; Zhou, Guofei; Chan, Stephen Y.; Das, Saumta; Sundd, Prithu (John Wiley & Sons Inc., 2023-02-01)

Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids, proteins, lipids and metabolites that play versatile roles in intercellular and interorgan communication. The capability to modulate ...
TOP-EVs: Technology of Protein delivery through Extracellular Vesicles is a versatile platform for intracellular protein delivery

Ilahibaks, Nazma F.; Ardisasmita, Arif I.; Xie, Songpu; Gunnarsson, Anders; Brealey, Joseph; Vader, Pieter; de Jong, Olivier G.; de Jager, Saskia; Dekker, Niek; Peacock, Ben; Schiffelers, Raymond M.; Sluijter, Joost P.G.; Lei, Zhiyong (Elsevier, 2023-03)

Extracellular vesicles (EVs) have emerged as biocompatible drug delivery vehicles due to their native ability to deliver bioactive cargo to recipient cells. However, the application of EVs as a therapeutic delivery vehicle ...
High-Grade Serous Carcinoma at Risk-Reducing Salpingo-Oophorectomy in Asymptomatic Carriers of BRCA1/2 Pathogenic Variants: Prevalence and Clinical Factors.

HEBON Investigators (Lippincott Williams & Wilkins, 2023-05-10)

PURPOSE: To investigate the prevalence of and clinical factors associated with high-grade serous carcinoma (HGSC) at risk-reducing salpingo-oophorectomy (RRSO) in asymptomatic BRCA1/2-pathogenic variant (PV) carriers. ...
ASO Author Reflections: The Role of Surgeons and Nurse Specialists in the Mainstreaming of Genetic Testing for Breast Cancer Patients

Bokkers, Kyra; Ausems, Margreet G E M (Springer New York, 2023-06)
Epidemiology, Clinical Features, and Antimicrobial Resistance of Invasive Escherichia Coli Disease in Patients Admitted in Tertiary Care Hospitals

Doua, Joachim; Geurtsen, Jeroen; Rodriguez-Baño, Jesus; Cornely, Oliver A; Go, Oscar; Gomila-Grange, Aina; Kirby, Andrew; Hermans, Peter; Gori, Andrea; Zuccaro, Valentina; Gravenstein, Stefan; Bonten, Marc; Poolman, Jan; Sarnecki, Michal (Oxford University Press, 2023-02)

BACKGROUND: Invasive Escherichia coli disease (IED), including bloodstream infection, sepsis, and septic shock, can lead to high hospitalization and mortality rates. This multinational study describes the clinical profile ...

Now showing items 10481-10500 of 40729