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UMC Repository: Recent submissions

  • Dekkers, Johanna F.; Whittle, James R.; Vaillant, François; Chen, Huei Rong; Dawson, Caleb; Liu, Kevin; Geurts, Maarten H.; Herold, Marco J.; Clevers, Hans|info:eu-repo/dai/nl/07164282X; Lindeman, Geoffrey J.; Visvader, Jane E. (2020-05-01)
    Breast cancer is characterized by histological and functional heterogeneity, posing a clinical challenge for patient treatment. Emerging evidence suggests that the distinct subtypes reflect the repertoire of genetic ...
  • Kops, Geert J.P.L.|info:eu-repo/dai/nl/226311481; Snel, Berend; Tromer, Eelco C. (Cell Press, 2020-05-18)
    The tremendous diversity in eukaryotic life forms can ultimately be traced back to evolutionary modifications at the level of molecular networks. Deep understanding of these modifications will not only explain cellular ...
  • Moris, Lisa; Cumberbatch, Marcus G; Van den Broeck, Thomas; Gandaglia, Giorgio; Fossati, Nicola; Kelly, Brian; Pal, Raj; Briers, Erik; Cornford, Philip; De Santis, Maria; Fanti, Stefano; Gillessen, Silke; Grummet, Jeremy P; Henry, Ann M; Lam, Thomas B L; Lardas, Michael; Liew, Matthew; Mason, Malcolm D; Omar, Muhammad Imran; Rouvière, Olivier; Schoots, Ivo G; Tilki, Derya; van den Bergh, Roderick C N; van Der Kwast, Theodorus H; van Der Poel, Henk G|info:eu-repo/dai/nl/113731469; Willemse, Peter-Paul M; Yuan, Cathy Y; Konety, Badrinath; Dorff, Tanya; Jain, Suneil; Mottet, Nicolas; Wiegel, Thomas (Elsevier, 2020-05)
    CONTEXT: The optimal treatment for men with high-risk localized or locally advanced prostate cancer (PCa) remains unknown. OBJECTIVE: To perform a systematic review of the existing literature on the effectiveness of the ...
  • Wekesah, Frederick M.; Mutua, Martin K.; Boateng, Daniel; Grobbee, Diederick E.|info:eu-repo/dai/nl/071889256; Asiki, Gershim; Kyobutungi, Catherine K.; Klipstein-Grobusch, Kerstin|info:eu-repo/dai/nl/182904156 (2020-06-01)
    Background: Cardiovascular diseases (CVD) cause 18 million deaths annually. Low- and middle-income countries (LMICs) account for 80% of the CVD burden, and the burden is expected to grow in the region in the coming years. ...
  • Duif, Iris; Wegman, Joost; Mars, Monica M; de Graaf, Cees; Smeets, Paul A M|info:eu-repo/dai/nl/304817740; Aarts, Esther (American Society for Nutrition, 2020-05-05)
    BACKGROUND: In the current obesogenic environment we often eat while electronic devices, such as smart phones, computers, or the television, distract us. Such "distracted eating" is associated with increased food intake ...
  • Carotid Stenosis Trialists' Collaboration (John Wiley and Sons Ltd, 2020-05-01)
    Background: The effectiveness of carotid endarterectomy (CEA) for stroke prevention depends on low procedural risks. The aim of this study was to assess the frequency and timing of procedural complications after CEA, which ...
  • Dutch Oligometastatic Prostate Cancer Working Group (2020-04)
    Background: Oligometastatic prostate cancer (OMPC) is a heterogeneous disease state that is imperfectly understood, and its clinical implications are unclear. Objective: To determine the consensus of a Dutch multidisciplinary ...
  • Fernández-Alvarez, Veronica; Suárez, Carlos; de Bree, Remco|info:eu-repo/dai/nl/344696359; Nixon, Iain J; Mäkitie, Antti A; Rinaldo, Alessandra; Downer, Jonathan; Ferlito, Alfio (Elsevier Ireland Ltd, 2020-04)
    The purpose of this study was to review the outcomes of the different therapies for extracranial head and neck arteriovenous malformations (AVMs). AVMs are high-flow congenital vascular anomalies. They are composed of a ...
  • Forsting, Johannes; Rehmann, Robert; Froeling, Martijn|info:eu-repo/dai/nl/413648354; Vorgerd, Matthias; Tegenthoff, Martin; Schlaffke, Lara (Springer Verlag, 2020-05)
    Objectives: To consider the tract-based analysis of DTI parameters in human muscle by assessing different fiber tracking stop criteria settings on diffusion parameters. Materials and methods: 30 healthy volunteers underwent ...
  • Boateng, Daniel; Danquah, Ina; Said-Mohamed, Rihlat; Smeeth, Liam; Nicolaou, Mary; Meeks, Karlijn; Beune, Erik; Addo, Juliet; Bahendeka, Silver; Agyei-Baffour, Peter; Mockenhaupt, Frank P; Spranger, Joachim; Schulze, Matthias B; Grobbee, Diederick E|info:eu-repo/dai/nl/071889256; Agyemang, Charles; Klipstein-Grobusch, Kerstin|info:eu-repo/dai/nl/182904156 (Cambridge University Press, 2020-06)
    Early-life environmental and nutritional exposures are considered to contribute to the differences in cardiovascular disease (CVD) burden. Among sub-Saharan African populations, the association between markers of early-life ...
  • Kühn, Tilman; Stepien, Magdalena; López-Nogueroles, Marina; Machado, Antje Damms; Sookthai, Disorn; Johnson, Theron; Roca, Marta; Hüsing, Anika; Maldonado, Sandra González; Cross, Amanda J; Murphy, Neil; Freisling, Heinz; Rinaldi, Sabina; Scalbert, Augustin; Fedirco, Veronika; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Sowah, Solomon A; Boeing, Heiner; Jakszyn, Paula; Sánchez, Maria-Jose; Merino, Susana; Colorado-Yohar, Sandra; Barricarte, Aurelio; Khaw, Kay Tee; Schmidt, Julie A; Perez-Cornago, Aurora; Trichopoulou, Antonia; Karakatsani, Anna; Thriskos, Paschalis; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Bueno-de-Mesquita, Bas|info:eu-repo/dai/nl/06929528X; van Gils, Carla H|info:eu-repo/dai/nl/17443068X; Heath, Alicia; Gunter, Marc J; Riboli, Elio; Lahoz, Agustín; Jenab, Mazda; Kaaks, Rudolf (Oxford University Press, 2020-05-01)
    BACKGROUND: Bile acids have been proposed to promote colon carcinogenesis. However, there are limited prospective data on circulating bile acid levels and colon cancer risk in humans. METHODS: Associations between prediagnostic ...
  • Lange, Maria Margaretha Alida de (Utrecht University, )
    Many sheep farm residents and veterinary students experienced a Q fever infection in the past, while only a few have had complaints of the acute illness. However, these people may still be at risk of a chronic infection. ...
  • Hout, Denise van (Utrecht University, )
    The human body is colonised with millions of bacteria, which are usually innocent. These bacteria can also become invasive and cause infections, prompting antibiotic treatment. Bacteria can become resistant to certain or ...
  • Scheele, Levina Geertruida Jacoba (Utrecht University, )
    Over the past decades, researchers have been trying to find the stem cells responsible for the development and homeostasis of the mammary gland. However, because of the lack of stem cell markers, the mammary stem cell ...
  • Abawi, Masieh (Utrecht University, 2020-05-18)
    In Chapter 2 we investigated the incidence, predictors, and prognostic effect of delirium on outcome after TAVR. Interestingly, we observed that delirium occurs among 13.4% of patients undergoing TAVR, and more commonly ...
  • Zwakenberg, Sabine R; Burgess, Stephen; Sluijs, Ivonne; Weiderpass, Elisabete; Beulens, Joline W J; van der Schouw, Yvonne T (Churchill Livingstone, 2020-04-01)
    BACKGROUND AND AIMS: Multiple observational studies and small-scale intervention studies suggest that high vitamin K intake is associated with improved markers for cardiovascular health. Circulating phylloquinone solely ...
  • van Erp, Nicole; Helsper, Charles; Olyhoek, Saskia; Janssen, Ramon; Winsveen, Amber; Peeters, Petra; de Wit, N. J. (Bohn Stafleu van Loghum, 2020-04-04)
    Bij 10 tot 25% van de patiënten met darmkanker duurt het lang voordat de huisarts tot verwijzing overgaat. Dat moet beter, want de ziektelast neemt af wanneer kanker tijdig wordt herkend. Lange duur tot verwijzing kan ...
  • Wekesah, FM; Klipstein-Grobusch, Kerstin; Grobbee, DE; Kadengye, Damazo; Asiki, Gershim; Kyobutungi, Catherine (Elsevier Science & Technology, 2020-04-10)
    Background: Cardiovascular diseases (CVD) comprise eighty percent of non-communicable disease (NCD) burden in low- and middle-income countries and are increasingly impacting the poor inequitably. Traditional and socioeconomic ...
  • Mekelenkamp, Hilda; Lankester, Arjan C; Bierings, Marc B; Smiers, Frans J W; de Vries, Martine C; Kars, Marijke C (Wiley-Liss Inc., 2020-05-01)
    BACKGROUND: In pediatric hematopoietic stem cell transplantation (HSCT), the end-of-life (EOL) phase and the loss of the child is often characterized by a sudden deterioration of the child following a period of intensive ...
  • Antwi, Edward|info:eu-repo/dai/nl/413586928; Amoakoh-Coleman, Mary|info:eu-repo/dai/nl/413586634; Vieira, Dorice L; Madhavaram, Shreya; Koram, Kwadwo A; Grobbee, Diederick E|info:eu-repo/dai/nl/071889256; Agyepong, Irene A; Klipstein-Grobusch, Kerstin|info:eu-repo/dai/nl/182904156 (Public Library of Science, 2020-04-21)
    INTRODUCTION: Prediction models for gestational hypertension and preeclampsia have been developed with data and assumptions from developed countries. Their suitability and application for low resource settings have not ...