Shukla, Rhythm; Peoples, Aaron J; Ludwig, Kevin C; Maity, Sourav; Derks, Maik G N; De Benedetti, Stefania; Krueger, Annika M; Vermeulen, Bram J A; Harbig, Theresa; Lavore, Francesca; Kumar, Raj; Honorato, Rodrigo V; Grein, Fabian; Nieselt, Kay; Liu, Yangping; Bonvin, Alexandre M J J; Baldus, Marc; Kubitscheck, Ulrich; Breukink, Eefjan; Achorn, Catherine; Nitti, Anthony; Schwalen, Christopher J; Spoering, Amy L; Ling, Losee Lucy; Hughes, Dallas; Lelli, Moreno; Roos, Wouter H; Lewis, Kim; Schneider, Tanja; Weingarth, Markus
(Cell Press, 2023-09-14)
Antimicrobial resistance is a leading mortality factor worldwide. Here, we report the discovery of clovibactin, an antibiotic isolated from uncultured soil bacteria. Clovibactin efficiently kills drug-resistant Gram-positive ...