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Utrecht University Repository: Recent submissions

  • Publics of policing: expanding approaches to nodal policing 
    Cooper-Knock, SJ; Berg, Julie; Diphoorn, Tessa (Routledge, 2024)
    The rise of private security across the globe has sparked concerns that a central public good is being corporatized, and that policing will no longer be guided by the interests of ‘the public'. In this article, we argue ...
  • Nitrate isotopes in catchment hydrology: insights, ideas and implications for models 
    Matiatos, Ioannis; Moeck, Christian; Vystavna, Yuliya; Marttila, Hannu; Orlowski, Natalie; Jessen, Søren; Evaristo, Jaivime; Sebilo, Mathieu; Koren, Gerbrand; Dimitriou, Elias; Müller, Sasha; Panagopoulos, Yiannis; Stockinger, Michael P. (Elsevier, 2023-11)
    Models that simulate water flow and quality, particularly related to nitrate ions, are commonly used on a catchment-scale. However, tracking nitrate ions is a challenging task due to the intricate processes that affect ...
  • Costs and benefits of protecting linear landscape elements: Applying systematic conservation planning on a case study in the Netherlands 
    Aschi, Flavia; Dekker, Stefan C; van Vuuren, Detlef P; Bogaart, Patrick W; Rijsdijk, Kenneth F; van Loon, E Emiel (Academic Press Inc., 2023-12-15)
    Protecting and increasing linear landscape elements (LLEs) in agricultural lands is regarded as a possible solution for a transition to a more biodiverse agricultural system. However, optimizing the spatial configuration ...
  • Tuning the Properties of Biobased PU Coatings via Selective Lignin Fractionation and Partial Depolymerization 
    Smit, Arjan T.; Bellinetto, Emanuela; Dezaire, Thomas; Boumezgane, Oussama; Riddell, Luke A.; Turri, Stefano; Hoek, Michiel; Bruijnincx, Pieter C.A.; Griffini, Gianmarco (American Chemical Society, 2023-05-08)
    Polyurethane (PU) coatings with high lignin content and tunable properties were made using a combination of fractionation and partial catalytic depolymerization as a novel strategy to tailor lignin molar mass and hydroxyl ...
  • Deep (phospho)proteomics profiling of pre- treatment needle biopsies identifies signatures of treatment resistance in HER2+ breast cancer 
    Debets, Donna O.; Stecker, Kelly E.; Piskopou, Anastasia; Liefaard, Marte C.; Wesseling, Jelle; Sonke, Gabe S.; Lips, Esther H.; Altelaar, Maarten (Cell Press, 2023-10-17)
    Patients with early-stage HER2-overexpressing breast cancer struggle with treatment resistance in 20%–40% of cases. More information is needed to predict HER2 therapy response and resistance in vivo. In this study, we ...
  • A cyclin-dependent kinase-mediated phosphorylation switch of disordered protein condensation 
    Valverde, Juan Manuel; Dubra, Geronimo; Phillips, Michael; Haider, Austin; Elena-Real, Carlos; Fournet, Aurélie; Alghoul, Emile; Chahar, Dhanvantri; Andrés-Sanchez, Nuria; Paloni, Matteo; Bernadó, Pau; van Mierlo, Guido; Vermeulen, Michiel; van den Toorn, Henk; Heck, Albert J.R.; Constantinou, Angelos; Barducci, Alessandro; Ghosh, Kingshuk; Sibille, Nathalie; Knipscheer, Puck; Krasinska, Liliana; Fisher, Daniel; Altelaar, Maarten (Nature Publishing Group, 2023-10-09)
    Cell cycle transitions result from global changes in protein phosphorylation states triggered by cyclin-dependent kinases (CDKs). To understand how this complexity produces an ordered and rapid cellular reorganisation, we ...
  • Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control 
    Yalçin, Zeliha; Koot, Daniëlle; Bezstarosti, Karel; Salas-Lloret, Daniel; Bleijerveld, Onno B.; Boersma, Vera; Falcone, Mattia; González-Prieto, Román; Altelaar, Maarten; Demmers, Jeroen A.A.; Jacobs, Jacqueline J.L. (American Society for Biochemistry and Molecular Biology Inc., 2023-06)
    Ubiquitination has crucial roles in many cellular processes, and dysregulation of ubiquitin machinery enzymes can result in various forms of pathogenesis. Cells only have a limited set of ubiquitin-conjugating (E2) enzymes ...
  • Regional vulnerability of brain white matter in vanishing white matter 
    Man, Jodie H.K.; van Gelder, Charlotte A.G.H.; Breur, Marjolein; Molenaar, Douwe; Abbink, Truus; Altelaar, Maarten; Bugiani, Marianna; van der Knaap, Marjo S. (BioMed Central, 2023-06-22)
    Vanishing white matter (VWM) is a leukodystrophy that primarily manifests in young children. In this disease, the brain white matter is differentially affected in a predictable pattern with telencephalic brain areas being ...
  • Optimized Suspension Trapping Method for Phosphoproteomics Sample Preparation 
    Wang, Fujia; Veth, Tim; Kuipers, Marije; Altelaar, Maarten; Stecker, Kelly E. (American Chemical Society, 2023-06-27)
    A successful mass spectrometry-based phosphoproteomics analysis relies on effective sample preparation strategies. Suspension trapping (S-Trap) is a novel, rapid, and universal method of sample preparation that is increasingly ...
  • Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development 
    Gan, Changpei; Wang, Jing; Wang, Yaogeng; Martínez-Chávez, Alejandra; Hillebrand, Michel; de Vries, Niels; Beukers, Joke; Lebre, Maria C.; Wagenaar, Els; Rosing, Hilde; Klarenbeek, Sjoerd; Bleijerveld, Onno B.; Song, Ji Ying; Altelaar, Maarten; Beijnen, Jos H.; Schinkel, Alfred H. (Elsevier Masson, 2023-08)
    Mammalian carboxylesterase 1 enzymes can hydrolyze many xenobiotic chemicals and endogenous lipids. We here identified and characterized a mouse strain (FVB/NKI) in which three of the eight Ces1 genes were spontaneously ...
  • How open science can support the 3Rs and improve animal research 
    Janssens, Monique; Gaillard, Stefan; Haan, Judith de; Leeuw, Wim de; Brooke, Matthew; Burke, Maura; Flores, Jacques; Kruijen, Iris; Menon, Julia; Smith, Adrian; Tiebosch, Ivo; Weijdema, Felix (2023-08)
    Open science in its broadest sense can make better science and provide benefits to researchers. When applied to animal experimentation, it can prevent unnecessary use of animals, because knowledge and experiences about ...
  • Development of teixobactin analogues containing hydrophobic, non-proteogenic amino acids that are highly potent against multidrug-resistant bacteria and biofilms 
    Parmar, Anish; Lakshminarayanan, Rajamani; Iyer, Abhishek; Goh, Eunice Tze Leng; To, Tsz Ying; Yam, Joey Kuok Hoong; Yang, Liang; Newire, Enas; Robertson, Maria C.; Prior, Stephen H.; Breukink, Eefjan; Madder, Annemieke; Singh, Ishwar (Elsevier Masson SAS, 2023-12-05)
    Teixobactin is a cyclic undecadepsipeptide that has shown excellent potency against multidrug-resistant pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). In ...
  • Improving the Cycle Life of Solid-State Batteries by Addition of Oxide Nanoparticles to a Complex Hydride Solid Electrolyte 
    de Kort, Laura; Ngene, Peter; Baricco, Marcello; de Jongh, Petra; Gulino, Valerio (American Chemical Society, 2023-03-02)
    We report that the addition of silica nanoparticles to the iodide-substituted LiBH4 (h-Li(BH4)0.8(I)0.2) improves the ion conductivity and, remarkably, the cycle life of the all-solid state batteries. The h-Li(BH4)0.8(I)0.2-SiO2 ...
  • Influence of carbon support surface modification on the performance of nickel catalysts in carbon dioxide hydrogenation 
    Visser, Nienke L.; Verschoor, Juliette C.; Smulders, Luc C.J.; Mattarozzi, Francesco; Morgan, David J.; Meeldijk, Johannes D.; van der Hoeven, Jessi E.S.; Stewart, Joseph A.; Vandegehuchte, Bart D.; de Jongh, Petra E. (Elsevier, 2023-06-01)
    The interaction between metal nanoparticles and a support is of key importance in catalysis. In this study, we demonstrate that the introduction of oxygen- or nitrogen-containing surface groups on a graphite nanoplatelet ...
  • Carbon nanofiber growth from methane over carbon-supported NiCu catalysts: Two temperature regimes 
    Schoemaker, Suzan E.; Welling, Tom A.J.; Wezendonk, Dennie F.L.; Reesink, Bennie H.; van Bavel, Alexander P.; de Jongh, Petra E. (Elsevier, 2023-06-01)
    An alternative route towards COx-free production of hydrogen is the thermal catalytic decomposition of methane. In addition to hydrogen, valuable carbon nanomaterials can be formed. Carbon nanofiber formation from methane ...
  • Silver Catalysts Supported on High Surface Area α-Alumina: Effect of Carbohydrate Template Size and Heat Treatment on Phase Purity 
    Keijzer, Claudia J.; Dalebout, Remco; de Rijk, Jan Willem; Lockemeyer, John R.; Lohr, Tracy L.; van den Brink, Peter; de Jongh, Petra E. (Wiley - VCH Verlag GmbH & CO. KGaA, 2023-08-07)
    α-Alumina is a non-porous metal oxide with applications in ceramics and catalysis. Introducing pores into this material to create catalytically relevant surface area is challenging due to phase transitions over a wide ...
  • Surface-Modified Carbon Materials for CO2 Electroreduction 
    Mattarozzi, Francesco; Tapia Rosales, Marisol; van de Poll, Rim C.J.; Hensen, Emiel J.M.; Ngene, Peter; de Jongh, Petra E. (Wiley-VCH Verlag, 2023-10-02)
    The electrochemical reduction of CO2 to produce sustainable fuels and chemicals has attracted great attention in recent years. It is shown that surface-modified carbons catalyze the CO2RR. This study reports a strategy to ...
  • Direct Observation of Ni Nanoparticle Growth in Carbon-Supported Nickel under Carbon Dioxide Hydrogenation Atmosphere 
    Visser, Nienke L.; Turner, Savannah J.; Stewart, Joseph A.; Vandegehuchte, Bart D.; van der Hoeven, Jessi E.S.; de Jongh, Petra E. (American Chemical Society, 2023-08-08)
    Understanding nanoparticle growth is crucial to increase the lifetime of supported metal catalysts. In this study, we employ in situ gas-phase transmission electron microscopy to visualize the movement and growth of ensembles ...
  • Carbon Nanofiber Growth Rates on NiCu Catalysts: Quantitative Coupling of Macroscopic and Nanoscale In Situ Studies 
    Welling, Tom A.J.; Schoemaker, Suzan E.; de Jong, Krijn P.; de Jongh, Petra E. (American Chemical Society, 2023-08-17)
    Since recently, gas-cell transmission electron microscopy allows for direct, nanoscale imaging of catalysts during reaction. However, often systems are too perturbed by the imaging conditions to be relevant for real-life ...
  • Alkylamine-Functionalized Carbon Supports to Enhance the Silver Nanoparticles Electrocatalytic Reduction of CO2 to CO 
    Mattarozzi, Francesco; van den Akker, Karen; Peerlings, Matt L.J.; Vink-van Ittersum, Maaike E.T.; Visser, Nienke L.; van de Poll, Rim C.J.; Hensen, Emiel J.M.; Ngene, Peter; de Jongh, Petra E. (John Wiley and Sons Ltd, 2023-10-02)
    Silver electrocatalysts enable the conversion of CO2 to CO, thereby facilitating the transition to a carbon neutral society. To lower the cost of the expensive metal, silver nanostructures are often supported on carbon. ...