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Now showing items 4261-4280 of 95693

Finding equitable solutions to the land-based sources of marine plastic pollution: Sovereignty as a double-edged sword

Guggisberg, Solène (Elsevier Limited, 2023-11-30)

Marine litter is a global and transboundary pollution problem. Recent attention has focused on the impact of this issue on areas beyond national jurisdiction. In many cases, marine litter is traced to a coastal State where ...
Ten-fold Robust Expansion Microscopy

Damstra, Hugo G.J.; Mohar, Boaz; Eddison, Mark; Akhmanova, Anna; Kapitein, Lukas C.; Tillberg, Paul W. (Bio-protocol LLC, 2023-06-20)

Expansion microscopy (ExM) is a powerful technique to overcome the diffraction limit of light microscopy that can be applied in both tissues and cells. In ExM, samples are embedded in a swellable polymer gel to physically ...
CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side

van den Berg, Cyntha M.; Volkov, Vladimir A.; Schnorrenberg, Sebastian; Huang, Ziqiang; Stecker, Kelly E.; Grigoriev, Ilya; Gilani, Sania; Frikstad, Kari Anne M.; Patzke, Sebastian; Zimmermann, Timo; Dogterom, Marileen; Akhmanova, Anna (Rockefeller University Press, 2023-04-03)

Microtubules are dynamic cytoskeletal polymers, and their organization and stability are tightly regulated by numerous cellular factors. While regulatory proteins controlling the formation of interphase microtubule arrays ...
Phase separation on microtubules: from droplet formation to cellular function?

Volkov, Vladimir A.; Akhmanova, Anna (Elsevier Limited, 2024-01)

Microtubules are cytoskeletal polymers that play important roles in numerous cellular processes, ranging from the control of cell shape and polarity to cell division and intracellular transport. Many of these roles rely ...
GelMap: intrinsic calibration and deformation mapping for expansion microscopy

Damstra, Hugo G.J.; Passmore, Josiah B.; Serweta, Albert K.; Koutlas, Ioannis; Burute, Mithila; Meye, Frank J.; Akhmanova, Anna; Kapitein, Lukas C. (Nature Publishing Group, 2023-10)

Expansion microscopy (ExM) is a powerful technique to overcome the diffraction limit of light microscopy by physically expanding biological specimen in three dimensions. Nonetheless, using ExM for quantitative or diagnostic ...
Compressive forces stabilize microtubules in living cells

Li, Yuhui; Kučera, Ondřej; Cuvelier, Damien; Rutkowski, David M.; Deygas, Mathieu; Rai, Dipti; Pavlovič, Tonja; Vicente, Filipe Nunes; Piel, Matthieu; Giannone, Grégory; Vavylonis, Dimitrios; Akhmanova, Anna; Blanchoin, Laurent; Théry, Manuel (Nature Publishing Group SN -, 2023-07)

Microtubules are cytoskeleton components with unique mechanical and dynamic properties. They are rigid polymers that alternate phases of growth and shrinkage. Nonetheless, the cells can display a subset of stable microtubules, ...
Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity

Vennin, Claire; Cattaneo, Chiara M; Bosch, Leontien; Vegna, Serena; Ma, Xuhui; Damstra, Hugo G J; Martinovic, Moreno; Tsouri, Efi; Ilic, Mila; Azarang, Leyla; van Weering, Jan R T; Pulver, Emilia; Zeeman, Amber L; Schelfhorst, Tim; Lohuis, Jeroen O; Rios, Anne C; Dekkers, Johanna F; Akkari, Leila; Menezes, Renee; Medema, Rene; Baglio, Serena R; Akhmanova, Anna; Linn, Sabine C; Lemeer, Simone; Pegtel, Dirk M; Voest, Emile E; van Rheenen, Jacco (Cell Press, 2023-06-12)

Although treatment with taxanes does not always lead to clinical benefit, all patients are at risk of their detrimental side effects such as peripheral neuropathy. Understanding the in vivo mode of action of taxanes can ...
Jérôme Duberry (2022) Artificial Intelligence and Democracy: Risks and Promises of AI-mediated citizen-government relations, Edward Elgar: Cheltenham

Fest, Isabelle (IOS Press, 2023-09-05)
Dipolar tidal effects in gravitational waves from scalarized black hole binary inspirals in quadratic gravity

Gemeren, Iris van; Shiralilou, Banafsheh; Hinderer, Tanja (American Institute of Physics, 2023-07-15)

Gravitational waves (GWs) from merging binary black holes (BHs) enable unprecedented tests of gravitational theories beyond Einstein's General Relativity (GR) in highly nonlinear, dynamical regimes. Such GW measurements ...
Effect of dynamical gravitomagnetic tides on measurability of tidal parameters for binary neutron stars using gravitational waves

Gupta, Pawan Kumar; Steinhoff, Jan; Hinderer, Tanja (American Institute of Physics, 2023-12-15)

Gravitational waves (GWs) from binary neutron stars (NSs) have opened unique opportunities to constrain the nuclear equation of state by measuring tidal effects associated with the excitation of characteristic modes of the ...
Classification of Atretic Small Antral Follicles in the Human Ovary

Wei, Fu; Fan, Xueying; Del Valle, Julieta S; Asseler, Joyce D; van der Meeren, Lotte E; Cheng, Hui; Roelen, Bernard A J; Louwe, Leoni A; Pilgram, Gonneke S K; van der Westerlaken, Lucette A J; van Mello, Norah M; Chuva de Sousa Lopes, Susana M (MDPI AG, 2023-12-01)

The reproductive lifespan in humans is regulated by a delicate cyclical balance between follicular recruitment and atresia in the ovary. The majority of the small antral follicles present in the ovary are progressively ...
Inclusive and multiplicity dependent production of electrons from heavy-flavour hadron decays in pp and p-Pb collisions

ALICE Collaboration (Springer Verlag, 2023-08)

Measurements of the production of electrons from heavy-flavour hadron decays in pp collisions at s = 13 TeV at midrapidity with the ALICE detector are presented down to a transverse momentum (p T) of 0.2 GeV/c and up to p ...
Short-term residential exposure to endotoxin emitted from livestock farms in relation to lung function in non-farming residents

de Rooij, Myrna M T; Erbrink, Hans J; Smit, Lidwien A M; Wouters, Inge M; Hoek, Gerard; Heederik, Dick J J (Academic Press Inc., 2024-02-15)

BACKGROUND: Evidence on the public health relevance of exposure to livestock farm emissions is increasing. Research mostly focused on chemical air pollution, less on microbial exposure, while endotoxins are suggested ...
Clarifying and strengthening the role of law and governance in climate scenario frameworks

Triyanti, Annisa; Du, Haomiao; Hegger, Dries L.T.; Driessen, Peter P.J.; van Rijswick, Helena F.M.W.; Scown, Murray; Gilissen, Herman Kasper (Elsevier BV, 2023-12)

Shared socio-economic pathways (SSPs) and shared policy assumptions (SPAs) are lauded as a common basis for climate scenario research across disciplines, yet they lack essential legal and governance elements that are ...
Continued adaptation of A/H2N2 viruses during pandemic circulation in humans

Kutter, Jasmin S.; Linster, Martin; de Meulder, Dennis; Bestebroer, Theo M.; Lexmond, Pascal; Rosu, Miruna E.; Richard, Mathilde; de Vries, Robert P.; Fouchier, Ron A.M.; Herfst, Sander (Society for General Microbiology, 2023-08-31)

Influenza A viruses of the H2N2 subtype sparked a pandemic in 1957 and circulated in humans until 1968. Because A/H2N2 viruses still circulate in wild birds worldwide and human population immunity is low, the transmissibility ...
Martin Brückner; Sandy Isenstadt; Sarah Wasserman (Editors). Modelwork: The Material Culture of Making and Knowing.

Boumans, Marcel (University of Chicago, 2023-12)
Will restricting rural land expropriation reduce rural land value capture? Local government strategies through the lens of policy instruments

Wang, Weifang; Spit, Tejo (Liverpool University Press, 2023-11)

The practice of land value capture (LVC) from collectively owned rural land is undergoing changes in rural land marketisation as local governments are constrained in their power to expropriate rural land. Previous studies ...
Quantification of bone surface textures: exploring a new method of ontogenetic ageing

de Rooij, Jimmy; Vintges, Marleen; Zuidwijk, Thim; Heerkens, Carel; Schulp, Anne (Springer, 2023-12-13)

Identification of ontogenetic age classes plays an important role in the fields of zoology, palaeontology and archaeology, where accurate age classifications of (sub)fossil remains are a crucial component for the reconstruction ...
Resurveying inner-alpine dry grasslands after 70 years calls for integrative conservation efforts

Kindermann, Elisabeth; Ebner, Manuel; Hölzel, Norbert; Bonari, Gianmaria; Wassen, Martin Joseph; Wellstein, Camilla (Elsevier BV, 2024-01)

European inner-alpine dry grasslands face substantial threats within the increasingly human-altered landscape, endangering their persistence. To understand changes in dry grassland communities, we revisited historical ...
Cerebrospinal Fluid Concentration of the RET Inhibitor Pralsetinib: A Case Report

de Jong, Loek A W; Sparidans, Rolf W; van den Heuvel, Michel M (S. Karger AG, 2023-12-13)

INTRODUCTION: Pralsetinib is used to treat metastatic RET fusion-positive non-small cell lung cancer. Preclinical studies of pralsetinib have shown blood-brain barrier (BBB) penetration and intracranial activity. The ...

Now showing items 4261-4280 of 95693