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Employee skills for circular business model implementation: A taxonomy

Straub, Lucas; Hartley, Kris; Dyakonov, Ivan; Gupta, Harsh; van Vuuren, Detlef; Kirchherr, Julian (Elsevier, 2023-07)

A growing body of scholarship has examined circular business models as a pathway towards sustainability. However, employee skills to support such business models have been largely overlooked. Addressing this research gap, ...
Efficiently simulating Lagrangian particles in large-scale ocean flows — Data structures and their impact on geophysical applications

Kehl, Christian; Nooteboom, Peter D.; Kaandorp, Mikael L.A.; van Sebille, Erik (Elsevier, 2023-06)

Studying oceanography by using Lagrangian simulations has been adopted for a range of scenarios, such as the determining the fate of microplastics in the ocean, simulating the origin locations of microplankton used for ...
Mechanisms of Sapropel Formation

Dirksen, Jan Pieter (Utrecht UniversityUU Dept of Earth Sciences, 2023-07-06)

In paleoceanography, physical and chemical processes of the oceans are studied throughout geological history. The sediments that constantly accumulate on the sea floor reflect the oceanographic conditions at the time of ...
Beyond the energy transition: Modelling of integrated multi-energy systems for a sustainable industrial transformation

Weimann, Lukas (Utrecht University, 2023-06-06)

This thesis aims to act as a catalyst for research at the intersection of energy transition and industrial transformation by providing a modelling toolbox suited for the application to industrial energy systems. The modelling ...
Change in prescription pattern as a potential marker for adverse drug reactions of angiotensin converting enzyme inhibitors

Mahmoud Pour, S.H.; Asselbergs, Folkert W; de Keyser, Catherine E; Souverein, P.C.; Hofman, A.; Stricker, Bruno H Ch; de Boer, A.; van der Zee, A.H. (Springer, 2015)

Background Angiotensin converting enzyme inhibitors (ACEIs) are among the most frequently prescribed groups of medications. ACEI-induced adverse drug reactions (ADRs) are the main reason to discontinue or switch ACEI ...
Use of antihypertensive agents and the risk of out-of-hospital cardiac arrest: A case control study

Alharbi, Fawaz F.; Souverein, Patrick C.; Blom, Marieke T.; Tan, Hanno L.; De Boer, Anthonius; Klungel, Olaf H. (John Wiley and Sons Ltd, 2015-09-01)

Background: Sudden cardiac arrest (SCA) is a complex multifactorial condition and is commonly caused by ventricular tachycardia/fibrillation (VT/VF). Some antihypertensive agents such as thiazides are associated with ...
Correction: Efficacy and Safety Assessment of the Addition of Bevacizumab to Adjuvant Therapy Agents in Cancer Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Ahmadizar, Fariba; Onland-Moret, N Charlotte; de Boer, Anthonius; Liu, Geoffrey; Maitland-van der Zee, Anke H (Public Library of Science, 2015)
Methods of defining the noninferiority margin: A systematic review

Althunian, Turki A.I.; De Boer, Anthonius; Klungel, Olaf H.; Insani, Widya N.; Groenwold, Rolf H.H. (John Wiley and Sons Ltd, 2016-08-01)

Background: Noninferiority trials are conducted to investigate whether the efficacy of the test drug is not worse than the active comparator based on a predefined noninferiority margin. There is no consensus on a preferred ...
Early life antibiotic exposure is associated with an increased risk of atopic eczema and hay fever

Ahmadizar, F.; Vijverberg, S.; Arets, H.; de Boer, Anthonius; Garssen, J.; Kraneveld, A.D.; Maitland-Van Der Zee, A.-H. (Blackwell Publishing Ltd, 2016-08-01)

Background: Several studies suggested that early life exposure to antibiotics is associated with an increased risk of developing allergies later in life, but results are inconsistent. In this study we aimed to systematically ...
Severity of Diabetes Mellitus and Total Hip or Knee Replacement

Nielen, J.T.H.; Emans, P.J.; Dagnelie, P.C.; Boonen, A.; Lalmohamed, A.; De Boer, A.; Van Den Bemt, B.J.F.; De Vries, F. (Lippincott Williams and Wilkins, 2016)

Permissions RESEARCH ARTICLE: OBSERVATIONAL STUDY Severity of Diabetes Mellitus and Total Hip or Knee Replacement A Population-Based Case–Control Study Nielen, Johannes T.H. MSc; Emans, Pieter J. PhD; Dagnelie, Pieter C. ...
Determinants of angiotensin converting enzyme-inhibitor (ACEI) intolerance and angioedema in the UK clinical practice research datalink

Mahmoud Pour, Seyed Hamidreza; Baranova, E V; Souverein, P C; Asselbergs, F W; de Boer, A; Maitland-van der Zee, A H; PREDICTION-ADR Consortium (NLM (Medline), 2016)

AIM: In this study we aimed to describe the occurrence and determinants of ACE-inhibitor (ACEI) intolerance and angioedema (AE) among patients initiating ACEI therapy in a real-world primary care population. METHODS: Two ...
Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis

Ahmadizar, Fariba; Vijverberg, Susanne J H; Arets, Hubertus G M; de Boer, Anthonius; Lang, Jason E; Kattan, Meyer; Palmer, Colin N A; Mukhopadhyay, Somnath; Turner, Steve; Maitland-van der Zee, Anke H (European Respiratory Society, 2016)

To estimate the association between obesity and poor asthma control or risk of exacerbations in asthmatic children and adolescents, and to assess whether these associations are different by sex.A meta-analysis was performed ...
PPAR-α genetic variants influence on-treatment platelet reactivity in patients treated with clopidogrel and lipid-lowering drugs and undergoing non-urgent percutaneous coronary intervention with stent implantation

Yasmina, Alfi; Bergmeijer, Thomas O; Janssen, Paul W A; Vos, Gerrit J.A.; Hackeng, Christian M; De Boer, Anthonius; Klungel, Olaf H.; Ten Berg, Jurrien M; Deneer, Vera H M (John Wiley and Sons Ltd, 2017-08-01)

Background: Response to clopidogrel varies between patients, due to many factors, like polymorphisms in genes encoding for metabolizing enzymes. The CYP3A4∗22 polymorphism has been proven to decrease the expression of ...
Noacs replace VKA as preferred oral anticoagulant among new patients

Van Den Heuvel, Jan Maurik; Hövels, Anke M.; Büller, Harry R; Mantel-Teeuwisse, A.K.; De Boer, A.; Maitland-Van Der Zee, A.H. (John Wiley and Sons Ltd, 2017-08-01)

Background: In 2012, around 400,000 patients in the Netherlands were treated with vitamin K antagonists (VKA) for thromboembolic diseases. Since 2011, non-VKA oral anticoagulants (NOACs) have been available. NOACs do not ...
Patterns of antiplatelet therapy in patients with ischaemic stroke or transient ischaemic attack

Rahman, Norazida A.B.; Yasmina, Alfi; De Boer, Anthonius; Deneer, Vera H M; Souverein, Patrick C.; Klungel, Olaf H. (John Wiley and Sons Ltd, 2017-08-01)

Background: Antiplatelet drugs are indicated for the secondary prevention in ischaemic stroke or transient ischemic attack (TIA) patients. Objectives: This study aimed to assess the trend in antiplatelet drugs utilisation ...
Incidence of bleeding and thrombotic events in non-institutionalized paediatric patients using warfarin in the united kingdom

Maagdenberg, Hedy; Souverein, Patrick C.; Bierings, Marc B; De Boer, Anthonius; Maitland-Van Der Zee, Anke H. (John Wiley and Sons Ltd, 2017-08-01)

Background: Dosing of vitamin K antagonists (VKA) is complex with large inter- and intra-individual variability in patients' required VKA dose. Over- and underdosing can result in bleeding and thrombotic events. The incidence ...
The children anticoagulation and pharmacogenetics study (CAPS): Developing a dosing algorithm for acencocoumarol in paediatric patients

Maagdenberg, Hedy; Bierings, Marc B; De Boer, Anthonius; Maitland-Van Der Zee, Anke H. (John Wiley and Sons Ltd, 2017-08-01)

Background: Dosing of vitamin K antagonists (VKA) in paediatric patients is complex. The large variability in VKA dose requirement asks for elucidating the factors associated with this variability and taking these into ...
Early HTA in pharmacogenomics: A case example in cardiovascular drugs

Baranova, Ekaterina V.; Geenen, Joost W.; Asselbergs, Folkert W; Palmer, Colin Na; De Boer, Anthonius; Maitland-Van Der Zee, Anke-Hilse; Hövels, Anke M. (John Wiley and Sons Ltd, 2017-08-01)

Background: ACE inhibitors (ACEi) are commonly used cardiovascular drugs. In a small percentage (0.2%) of patients, these drugs can cause a severe and possibly lethal adverse drug reaction (ADR), angioedema. A pharmacogenetic ...
The risk of acute myocardial infarction associated with non-steroidal anti-inflammatory drugs users: Impact of additional confounding control for variables collected from self-reported data

Bakhriansyah, Mohammad; Souverein, Patrick; De Boer, Anthonius; Klungel, Olaf H. (John Wiley and Sons Ltd, 2017-08-01)

Background: Several observational studies have employed electronic health databases to study the association between non-steroidal anti-inflammatory drugs (NSAIDs) and myocardial infarction. Because some important potential ...
The impact of raw fermented milk products on perceived health and mood among Dutch adults

Baars, Ton; Berge, Catharina; Garssen, Johan; Verster, Joris (Emerald Group Publishing Ltd., 2019-12-12)

Purpose: The purpose of this paper was to evaluate health conditions prior to and at least two months after the start of consuming raw fermented milk (RFM) products. Design/methodology/approach: One-Item health score, ...

Now showing items 8741-8760 of 95693