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Now showing items 8341-8360 of 95693

Support of working informal caregivers in the Netherlands and in Germany

Heeger-Hertter, S.E.; Koopmans, Ivy (SSRN, 2022-11-15)

The division of responsibilities and organizational structures in the field of long-term care is a subject of much discussion. This is made even more clear by the EU Work-Life Balance Directive of June 2019. In view of the ...
Establishing relationships between particle-induced in vitro and in vivo inflammation endpoints to better extrapolate between in vitro markers and in vivo fibrosis

McLean, Polly; Mueller, William; Gosens, Ilse; Cassee, Flemming R; Rothen-Rutishauser, Barbara; Boyles, Matthew; Tran, Lang (BioMed Central, 2023-02-09)

BACKGROUND: Toxicity assessment for regulatory purposes is starting to move away from traditional in vivo methods and towards new approach methodologies (NAM) such as high-throughput in vitro models and computational tools. ...
Placental-fetal distribution of carbon particles in a pregnant rabbit model after repeated exposure to diluted diesel engine exhaust

Bongaerts, Eva; Nawrot, Tim S; Wang, Congrong; Ameloot, Marcel; Bové, Hannelore; Roeffaers, Maarten Bj; Chavatte-Palmer, Pascale; Couturier-Tarrade, Anne; Cassee, Flemming R (BioMed Central, 2023-05-18)

BACKGROUND: Airborne pollution particles have been shown to translocate from the mother's lung to the fetal circulation, but their distribution and internal placental-fetal tissue load remain poorly explored. Here, we ...
Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model

Warmink, Kelly; Rios, Jaqueline L; Varderidou-Minasian, Suzy; Torres-Torrillas, Marta; van Valkengoed, Devin R; Versteeg, Sabine; Eijkelkamp, Niels; Weinans, Harrie; Korthagen, Nicoline M; Lorenowicz, Magdalena J (BioMed Central, 2023-05-24)

BACKGROUND: Mesenchymal stromal/stem cells (MSCs) and MSC-derived extracellular vesicles (MSC-EVs) hold promise as a disease modifying treatment in osteoarthritis (OA). Obesity, and its associated inflammation, contribute ...
How to power an off-grid telescope?: Comparative life cycle assessment of renewable-based energy systems to power to telescope

Viole, Isabelle; Valenzuela Venegas, Guillermo; Shen, Li; Ramirez Camargo, Luis; Sartori, Sabrina (2023-04-23)
Balancing or prioritising for sustainable development? Perceptions of sustainability integration among professionals

Montesano, Francesco S.; Biermann, Frank; Kalfagianni, Agni; Vijge, Marjanneke J. (Wiley, 2023-06)

The effective integration of the environmental with the economic and social dimensions of sustainability will only succeed when the core problem perceptions of professionals in these fields adjust as well. Yet, while ...
Applications of evidence synthesis in chemical health risk assessment

Scholten, Bernice Jannigje Wilhelmina (Utrecht University, 2023-06-27)

This thesis aimed to combine all available evidence within and across evidence streams, i.e. evidence synthesis, to strengthen chemical risk assessment. The evidence considered was published data of the following evidence ...
Post Migration Parenthood as Social Site for Learning and Negotiation: Understanding Parenting in the Context of a Bottom-Up Programme Evaluation Study

van Beurden, Sparky Lola (Utrecht University, 2023-06-23)

Research shows how migration has a profound impact on people’s parenting experiences and practices, as it disrupts and rearranges social contexts, cultural frames of reference and access to socioeconomic status and resources. ...
Drawing Conclusions from Cross-Lagged Relationships: Re-Considering the Role of the Time-Interval

Kuiper, Rebecca M.; Ryan, Oisín (Psychology Press Ltd, 2018)

The cross-lagged panel model (CLPM), a discrete-time (DT) SEM model, is frequently used to gather evidence for (reciprocal) Granger-causal relationships when lacking an experimental design. However, it is well known that ...
A critique of the cross-lagged panel model

Hamaker, E.L.; Kuiper, R.M.; Grasman, R.P.P.P. (NLM (Medline), 2015)

The cross-lagged panel model (CLPM) is believed by many to overcome the problems associated with the use of cross-lagged correlations as a way to study causal influences in longitudinal panel data. The current article, ...
Adaptation strategies of mutualistic rhizobacteria on Arabidopsis roots

Zhang, Hao (Utrecht University, 2023-07-03)

Beneficial plant root-associated microorganisms carry out a range of functions that are essential for plant performance. To study bacterial adaptation in the rhizosphere, we employed experimental evolution to track the ...
On pole position: new approaches to quantifying polar wander and relative paleomagnetic displacements

Vaes, Bram (Utrecht UniversityUU Dep of Earth Sciences, 2023-06-27)

Paleomagnetism provides the only quantitative tool to reconstruct the position and motion of tectonic plates and continents in deep geological time. These reconstructions often rely on apparent polar wander paths (APWPs), ...
National Institutions and Platform Evolution in the European Gig Economy

Koutsimpogiorgos, Nikolaos (Utrecht University, 2023-06-23)

In the past decade, the widespread use of smartphones, app software, and broadband internet access has led to the rise of internet platforms, particularly online marketplaces that connect job requesters with workers in ...
The flexibility of existing laws is an essential element of environmental governance

Garmestani, Ahjond; Craig, R.; Ruhl, J.B. (National Academy of Sciences, 2020-01-01)
Panarchy and management of lake ecosystems

Garmestani, Ahjond; Angeler, David; Allen, Craig; Gunderson, Lance; Johnson, Richard (The Resilience Alliance, 2021-03-01)

A key challenge of the Anthropocene is to confront the dynamic complexity of systems of people and nature to guide robust interventions and adaptations across spatiotemporal scales. Panarchy, a concept rooted in resilience ...
Uncertainty in non-CO2 greenhouse gas mitigation contributes to ambiguity in global climate policy feasibility

Harmsen, Mathijs; Tabak, Charlotte; Höglund-Isaksson, Lena; Humpenöder, Florian; Purohit, Pallav; van Vuuren, Detlef (Nature Publishing Group, 2023-12)

Despite its projected crucial role in stringent, future global climate policy, non-CO 2 greenhouse gas (NCGG) mitigation remains a large uncertain factor in climate research. A revision of the estimated mitigation potential ...
Individuals challenging directives in EU courts

Prechal, Sacha (Kluwer Law International, 2022)
De reikwijdte van de wettelijke zorgplichten voor de openbare drinkwatervoorziening en de leveringsplicht van drinkwaterbedrijven

Veldkamp, Aster; Gilissen, Herman Kasper; Groothuijse, Frank; van Rijswick, Helena (UCWOSL Utrecht University, 2023)
Impact of different destocking strategies on the resilience of dry rangelands

Vignal, Toyo; Baudena, Mara; Mayor, Angeles Garcia; Sherratt, Jonathan A (Wiley, 2023-05)

Half of the world's livestock live in (semi-)arid regions, where a large proportion of people rely on animal husbandry for their survival. However, overgrazing can lead to land degradation and subsequent socio-economic ...
The role of peatland degradation, protection and restoration for climate change mitigation in the SSP scenarios

Doelman, J C; Verhagen, W; Stehfest, E; Vuuren, D P van (IOP Publishing, 2023-09)

Peatlands only cover a small fraction of the global land surface (∼3%) but store large amounts of carbon (∼600 GtC). Drainage of peatlands for agriculture results in the decomposition of organic matter, leading to greenhouse ...

Now showing items 8341-8360 of 95693