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Now showing items 7541-7560 of 95693

Busulfan target exposure attainment in children undergoing allogeneic hematopoietic cell transplantation: a single day versus a multiday therapeutic drug monitoring regimen

Bognàr, T. (Tim); Kingma, J.S. (Jurjen); Smeijsters, E. H.(Erin); van der Elst, K. C.M.(Kim); de Kanter, C. T.M.(Klaartje); Lindemans, C. A.(Caroline); Egberts, A. C.G.(Toine); Bartelink, I. H.(Imke); Lalmohamed, A. (Arief) (Nature Publishing Group, 2023-07)

Busulfan exposure has previously been linked to clinical outcomes, hence the need for therapeutic drug monitoring (TDM). Study objective was to evaluate the effect of day 1 TDM-guided dosing (regimen d1) versus days 1 + 2 ...
Durvalumab after chemoradiotherapy in patients with stage III non-small-cell lung cancer: real-world outcomes versus clinical trial results

Verschueren, Marjon V; Dijs, Talitha; Gulikers, Judith L; Veelen, Ard van; Croes, Sander; Hendriks, Lizza El; Smit, Adrianus Aj; Bloem, Lourens T; Egberts, Antoine Cg; van de Garde, Ewoudt Mw; Peters, Bas Jm (BioMed Central, 2023-08-01)

Aim: We investigated the effectiveness of durvalumab post-concurrent CRT (cCRT) and post-sequential CRT (sCRT) versus cCRT and sCRT alone and compared these outcomes with the PACIFIC trial. Methods: Four cohorts of stage ...
Barriers and facilitators for the implementation of the CombiConsultation by general practitioners, pharmacists and practice nurses: a qualitative interview study

Meijvis, Valérie A M; Heringa, Mette; Kwint, Henk-Frans; de Wit, Niek J; Bouvy, Marcel L (Springer, 2023-08)

BACKGROUND: The CombiConsultation is a consultation with the pharmacist for patients with a chronic condition, aligned with the periodic consultation with the practice nurse or general practitioner. Implementation requires ...
Socioeconomic hardship, uncertainty about the future, and adolescent mental wellbeing over a year during the COVID-19 pandemic

Green, Kayla H.; Becht, Andrik; van de Groep, Suzanne; van der Cruijsen, Renske; Sweijen, Sophie W.; Crone, Eveline A (Wiley-Blackwell, 2023-08)

Socioeconomic vulnerabilities put adolescents at risk for mental wellbeing issues, also in times of a pandemic. In the present longitudinal online survey study, we explored changes in mental wellbeing (i.e., mood and life ...
Cruciale tekst: Theodor W. Adorno und Max Horkheimer, Dialektik der Aufklarung, Philosophische Fragmente (1947)

van Liere, Lucien (2014-11)

In 1947, Theodor W. Adorno and Max Horkheimer, two members of the so-called Frankfurt School of Sociology published The Dialectic of Enlightenment. The book, written in exile, did not study national-socialism as an accident ...
Contesting Religious Identities: An Introduction

Korte, A.J.A.C.M.; van Liere, L.M. (BrillBrill, 2017-01-01)
At the Threshold: A Panorama for Future Studies and Challenges to Religious Studies

van Liere, L.M. (BrillBrill, 2017-01-01)
Killing the Heirs of the Killers: Collective Memory, Religion and Violent Conflict

van Liere, L.M. (Cambridge Scholars Publishing, 2017)

This chapter considers the role of collective memory within the frame of religious traditions for the justification of violent conflict. In the first paragraphs, the relevance of the concept of cultural memory is explored ...
Governing systemic and cascading disaster risk in Indonesia: where do we stand and future outlook

Triyanti, Annisa; Surtiari, Gusti Ayu Ketut; Lassa, Jonatan; Rafliana, Irina; Hanifa, Nuraini Rahma; Muhidin, Mohamad Isnaeni; Djalante, Riyanti (Emerald Group Publishing Ltd., 2023-06-14)

Purpose This paper aims to identify key factors for a contextualised Systemic Risk Governance (SRG) framework and subsequently explore how systemic risks can be managed and how local institutional mechanisms can be tweaked ...
COP26 and the dynamics of anti‐fossil fuel norms

Asselt, Harro van; Green, Fergus (Wiley, 2023-05-01)

Notwithstanding the clear contribution of fossil fuel production and consumption to global greenhouse gas emissions, fossil fuels have remained largely outside the focus of the international regime established by the United ...
Developing a material flow monitor for the Netherlands from national statistical data

Delahaye, Roel; Tunn, Vivian S. C.; Tukker, Arnold (Wiley-Blackwell, 2023-04)

Effective monitoring of national circular economy policies requires consistent, national databases of material flows and environmental impacts. Yet, databases and indicators developed so far are scattered and inconsistent. ...
Towards a problem-oriented regional industrial policy: possibilities for public intervention in framing, valuation and market formation

Flanagan, Kieron; Uyarra, Elvira; Wanzenböck, Iris (Routledge, 2023)

Thinking about regional industrial policies remains focused on the supply of new knowledge, and recently also on grand challenges and missions, but takes problems, demand and market formation largely for granted. In this ...
Preductal Segmental Tubular Aortic Hypoplasia in Perinatally Died Stabyhoun Puppies

Staveren, Marie D. B. van; Grinwis, Guy C. M.; Toom, Marjolein L. den; Szatmári, Viktor (Multidisciplinary Digital Publishing Institute (MDPI), 2023-08)

Background: A high perinatal mortality rate in the Stabyhoun breed prompted one of the Dutch breeding organizations to start an investigation. Preductal segmental tubular aortic hypoplasia is an extremely rarely documented ...
Precision Medicine for More Oxygen (P4O2)-Study Design and First Results of the Long COVID-19 Extension

P4O2 Consortium; Weersink, Els J; van de Werken, Marco; de Wit-van Wijck, Yolanda; Young, Stewart; Nossent, Esther J (Multidisciplinary Digital Publishing Institute (MDPI), 2023-07)

Introduction: The coronavirus disease 2019 (COVID-19) pandemic has led to the death of almost 7 million people, however, with a cumulative incidence of 0.76 billion, most people survive COVID-19. Several studies indicate ...
Vaccination against Extracellular Vimentin for Treatment of Urothelial Cancer of the Bladder in Client-Owned Dogs

Engbersen, Diederik J. M.; Beijnum, Judy R. van; Roos, Arno; Beelen, Marit van; Haan, Jan David de; Grinwis, Guy C. M.; Schalken, Jack A.; Witjes, J. Alfred; Griffioen, Arjan W.; Huijbers, Elisabeth J. M. (Multidisciplinary Digital Publishing Institute (MDPI), 2023-08-03)

It was recently shown that targeting extracellular vimentin (eVim) is safe and effective in preclinical models. Here, we report the safety and efficacy in client-owned dogs with spontaneous bladder cancer of CVx1, an iBoost ...
High-Resolution Genotyping of Expressed Equine MHC Reveals a Highly Complex MHC Structure

Vasoya, Deepali; Tzelos, Thomas; Benedictus, Lindert; Karagianni, Anna Eleonora; Pirie, Scott; Marr, Celia; Oddsdóttir, Charlotta; Fintl, Constanze; Connelley, Timothy (Multidisciplinary Digital Publishing Institute (MDPI), 2023-07-10)

The Major Histocompatibility Complex (MHC) genes play a key role in a number of biological processes, most notably in immunological responses. The MHCI and MHCII genes incorporate a complex set of highly polymorphic and ...
Lipopolysaccharide-binding protein and future Parkinson's disease risk: a European prospective cohort

Zhao, Yujia; Walker, Douglas I; Lill, Christina M; Bloem, Bastiaan R; Darweesh, Sirwan K L; Pinto-Pacheco, Brismar; McNeil, Brooklyn; Miller, Gary W; Heath, Alicia K; Frissen, Myrthe; Petrova, Dafina; Sánchez, Maria-Jose; Chirlaque, María-Dolores; Guevara, Marcela; Zibetti, Maurizio; Panico, Salvatore; Middleton, Lefkos; Katzke, Verena; Kaaks, Rudolf; Riboli, Elio; Masala, Giovanna; Sieri, Sabina; Zamora-Ros, Raul; Amiano, Pilar; Jenab, Mazda; Peters, Susan; Vermeulen, Roel (BioMed Central, 2023-07-21)

INTRODUCTION: Lipopolysaccharide (LPS) is the outer membrane component of Gram-negative bacteria. LPS-binding protein (LBP) is an acute-phase reactant that mediates immune responses triggered by LPS and has been used as a ...
Longitudinal positron emission tomography and postmortem analysis reveals widespread neuroinflammation in SARS-CoV-2 infected rhesus macaques

Nieuwland, Juliana M; Nutma, Erik; Philippens, Ingrid H C H M; Böszörményi, Kinga P; Remarque, Edmond J; Bakker, Jaco; Meijer, Lisette; Woerdman, Noor; Fagrouch, Zahra C; Verstrepen, Babs E; Langermans, Jan A M; Verschoor, Ernst J; Windhorst, Albert D; Bontrop, Ronald E; de Vries, Helga E; Stammes, Marieke A; Middeldorp, Jinte (BioMed Central, 2023-07-29)

BACKGROUND: Coronavirus disease 2019 (COVID-19) patients initially develop respiratory symptoms, but they may also suffer from neurological symptoms. People with long-lasting effects after acute infections with severe ...
Beauveria bassiana rewires molecular mechanisms related to growth and defense in tomato

Proietti, Silvia; Falconieri, Gaia Salvatore; Laura, BERTINI; Pascale, Alberto; Bizzarri, Elisabetta; Morales-Sanfrutos, Julia; Sabidó, Eduard; Ruocco, Michelina; MAURILIA, MARIA MONTI; Russo, Assunta; Dziurka, Kinga; Ceci, Marcello; Loreto, Francesco; Caruso, Carla (Oxford University Press, 2023-08-03)

Plant roots can exploit beneficial associations with soil-inhabiting microbes, promoting growth and expanding the immune capacity of the host plant. In this work, we aimed to provide new information on changes occurring ...
Regelcomplexiteit in de ruimtelijke ordening

Boeve, Marlon; Groothuijse, Frank (Raad van State, 2023)

Now showing items 7541-7560 of 95693