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Utrecht University Repository: Recent submissions

  • Osteoimmunomodulatory GelMA/liposome coatings to promote bone regeneration of orthopedic implants 
    Jahanmard, F; Khodaei, A; Flapper, J; Dogan, O; Roohi, K; Taheri, P; Weinans, H; Storm, G; Croes, M; Mastrobattista, E; Amin Yavari, S (Elsevier, 2023-06)
    Despite being the most widely used biomaterials in orthopedic surgery, metallic implants do not induce new bone growth because they are bioinert. Surface biofunctionalization of implants with immunomodulatory mediators is ...
  • How the World Bank engages with the Sustainable Development Goal on reducing inequalities A case of organizational jiu-jitsu 
    Driel, Melanie; Biermann, Frank; Vijge, Marjanneke; Kim, Rakhyun (Oxford University Press, 2023-07-01)
    In 2015, the United Nations agreed on seventeen Sustainable Development Goals (SDGs) to mobilize various actors, including international organizations, for a global transformation toward sustainability. The expectation was ...
  • Translation certification for smart contracts 
    Krijnen, Jacco O.G.; Chakravarty, Manuel M.T.; Keller, Gabriele; Swierstra, Wouter (Elsevier, 2024-03)
    Compiler correctness is an old problem, but with the emergence of smart contracts on blockchains that problem presents itself in a new light. Smart contracts are self-contained pieces of software that control (valuable) ...
  • A correct-by-construction conversion from lambda calculus to combinatory logic 
    Swierstra, Wouter (Cambridge University Press [etc.], 2023)
    This pearl defines a translation from well-typed lambda terms to combinatory logic, where both the preservation of types and the correctness of the translation are enforced statically.
  • Climate change influences the risk of physically harmful human-wildlife interactions 
    Newsom, Amy; Sebesvari, Zita; Dorresteijn, Ine (Elsevier BV, 2023-10)
    Interactions with wildlife can pose substantial physical risk to humans, as well as damage efforts to protect the species involved. News reports of increasing dangerous interactions with animals indicate climate change may ...
  • Goblet cell interactions reorient bundled mucus strands for efficient airway clearance 
    Bos, Meike f; Ermund, Anna; Hansson, Gunnar c; De graaf, Joost (2023-11-01)
    The respiratory tract of larger animals is cleared by sweeping bundled strands along the airway surface. These bundled strands can be millimetric in length and consist of MUC5B mucin. They are produced by submucosal glands, ...
  • Prospective Passion and Social Capital within DotA 2 Players 
    Johnson, Daniel; Frommel, Julian; Louis, Winnifred; Lee, Matthew David; Tanjitpiyanond, Porntida; Mandryk, Regan L. (ACM, 2023-09-29)
    The Dualistic Model of Passion (obsessive and harmonious passion) can explain motivations for videogame play along with associated outcomes, such as the development of social capital; however, existing research exploring ...
  • Children’s domain-specific self-evaluations and global self-worth:: A preregistered cross-cultural meta-analysis 
    Tang, Yixin; Brummelman, Eddie; Novin, Sheida; Assink, Mark; Thomaes, Sander (SAGE Publications Ltd, 2023-11)
    Which domain-specific self-evaluations are most central to children’s global self-worth? And does this differ between countries with different levels of collectivism–individualism? We conducted a preregistered cross-cultural ...
  • Exploiting Substrate Specificities of 6-O-Sulfotransferases to Enzymatically Synthesize Keratan Sulfate Oligosaccharides 
    Wu, Yunfei; Vos, Gaël M.; Huang, Chin; Chapla, Digantkumar; Kimpel, Anne L.M.; Moremen, Kelley W.; de Vries, Robert P.; Boons, Geert Jan (American Chemical Society, 2023-11)
    Keratan sulfate (KS) is a glycosaminoglycan that is widely expressed in the extracellular matrix of various tissue types, where it is involved in many biological processes. Herein, we describe a chemo-enzymatic approach ...
  • Combination of deep XLMS with deep learning reveals an ordered rearrangement and assembly of a major protein component of the vaccinia virion 
    Mirzakhanyan, Yeva; Jankevics, Andris; Scheltema, Richard A; Gershon, Paul David (American Society for Microbiology, 2023-10)
    Vaccinia virus, the prototypical poxvirus and smallpox/monkeypox vaccine, has proven a challenging entity for structural biology, defying many of the approaches leading to molecular and atomic models for other viruses. Via ...
  • CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands 
    Rouillon, Clément; Eckhardt, Bruna V; Kollenstart, Leonie; Gruss, Fabian; Verkennis, Alexander E E; Rondeel, Inge; Krijger, Peter H L; Ricci, Giulia; Biran, Alva; van Laar, Theo; Delvaux de Fenffe, Charlotte M; Luppens, Georgiana; Albanese, Pascal; Sato, Koichi; Scheltema, Richard A; de Laat, Wouter; Knipscheer, Puck; Dekker, Nynke H; Groth, Anja; Mattiroli, Francesca (Oxford University Press, 2023-05-08)
    During every cell cycle, both the genome and the associated chromatin must be accurately replicated. Chromatin Assembly Factor-1 (CAF-1) is a key regulator of chromatin replication, but how CAF-1 functions in relation to ...
  • Revealing determinants of translation efficiency via whole-gene codon randomization and machine learning 
    Nieuwkoop, Thijs; Terlouw, Barbara R; Stevens, Katherine G; Scheltema, Richard A; de Ridder, Dick; van der Oost, John; Claassens, Nico J (Oxford University Press, 2023-03-21)
    It has been known for decades that codon usage contributes to translation efficiency and hence to protein production levels. However, its role in protein synthesis is still only partly understood. This lack of understanding ...
  • Towards a structurally resolved human protein interaction network 
    Burke, David F; Bryant, Patrick; Barrio-Hernandez, Inigo; Memon, Danish; Pozzati, Gabriele; Shenoy, Aditi; Zhu, Wensi; Dunham, Alistair S; Albanese, Pascal; Keller, Andrew; Scheltema, Richard A; Bruce, James E; Leitner, Alexander; Kundrotas, Petras; Beltrao, Pedro; Elofsson, Arne (Nature Publishing Group, 2023-02)
    Cellular functions are governed by molecular machines that assemble through protein-protein interactions. Their atomic details are critical to studying their molecular mechanisms. However, fewer than 5% of hundreds of ...
  • Late Cenozoic sea-surface-temperature evolution of the South Atlantic Ocean 
    Hoem, Frida S.; López-Quirós, Adrián; Lagemaat, Suzanna van de; Etourneau, Johan; Sicre, Marie-Alexandrine; Escutia, Carlota; Brinkhuis, Henk; Peterse, Francien; Sangiorgi, Francesca; Bijl, Peter K. (European Geosciences Union, 2023-10-13)
    At present, a strong latitudinal sea-surface-temperature (SST) gradient of g1/4g€¯16g€¯g exists across the Southern Ocean, maintained by the Antarctic Circumpolar Current (ACC) and a set of complex frontal systems. Together ...
  • Isotopic and magnetic proxies are good indicators of millennial-scale variability of the East Asian monsoon 
    Fuchs, Louise; Guo, Jingjing; Schefuß, Enno; Sun, Youbin; Guo, Fei; Ziegler, Martin; Peterse, Francien (Springer Nature, 2023-12)
    Past East Asian Monsoon variability has been reconstructed using oxygen isotopes of cave speleothems as well as proxy indicators from Chinese loess sequences. However, where the speleothem record is dominated by precession ...
  • Clinical management of feline chronic kidney disease in Portugal: a questionnaire-based study 
    Magalhães, Tomás Rodrigues; Lourenço, Ana Luísa; Corbee, Ronald Jan; Queiroga, Felisbina Luísa (W.B. Saunders Ltd, 2023-11-01)
    OBJECTIVES: The aim of the study was to characterise the clinical management of feline chronic kidney disease (CKD) by veterinary practitioners in Portugal. METHODS: A questionnaire-based study was designed to be completed ...
  • Spatial-temporal distribution and potential risk of pesticides in ambient air in the North China Plain 
    Zhao, Mingyu; Wu, Junxue; Figueiredo, Daniel M; Zhang, Yun; Zou, Ziyu; Cao, Yuxuan; Li, Jingjing; Chen, Xue; Shi, Shuping; Wei, Zhiyun; Li, Jindong; Zhang, Hongyan; Zhao, Ercheng; Geissen, Violette; Ritsema, Coen J; Liu, Xuejun; Han, Jiajun; Wang, Kai (Elsevier, 2023-12)
    The intensive use of pesticides in the North China Plain (NCP) has resulted in widespread contamination of pesticides in the local atmosphere, posing risks to air quality and human health. However, the occurrence and ...
  • Pesticide residues with hazard classifications relevant to non-target species including humans are omnipresent in the environment and farmer residences 
    Silva, Vera; Gai, Lingtong; Harkes, Paula; Tan, Gaowei; Ritsema, Coen; Alcon, Francsico; Contreras, Josefa; Abrantes, Nelson; Campos, Isabel; Baldi, Isabelle; Bureau, Mathilde; Christ, Florian; Mandrioli, Daniele; DARIA, SGARGI; Pasković, Igor; Pasković, Marija Polić; Glavan, Matjaž; Hofman, Jakub; Lwanga, Esperanza Huerta; Nørgaard, Trine; Bílková, Zuzana; Osman, Rima; Khurshid, Chrow; Navarro, Irene; Torre, Adrian de la; Sanz, Paloma; Martínez, María Ángeles; Dias, Jonatan; Mol, Hans; Gort, Gerrit; Figueiredo, Daniel Martins; Scheepers, Paul T.J.; Schlünssen, Vivi; Vested, Anne; Alaoui, Abdallah; Geissen, Violette (Elsevier, 2023-11)
    Intensive and widespread use of pesticides raises serious environmental and human health concerns. The presence and levels of 209 pesticide residues (active substances and transformation products) in 625 environmental ...
  • Salivary concentrations of secretory leukocyte protease inhibitor and matrix metallopeptidase-9 following a single bout of exercise are associated with intensity and hydration status 
    Knipping, Karen; Kartaram, Shirley W; Teunis, Marc; Zuithoff, Nicolaas P A; Buurman, Nicole; M'Rabet, Laura; van Norren, Klaske; Witkamp, Renger; Pieters, Raymond; Garssen, Johan (Public Library of Science, 2023)
    AIM: To investigate the effects of exercise on salivary concentrations of inflammatory markers by analyzing a panel of 25 inflammatory markers in subjects who had participated in bicycle ergometer tests varying in workload ...
  • How does it feel?: An exploration of neurobiological and clinical correlates of alexithymia in trauma-exposed police-officers with and without PTSD 
    van Sleeuwen, Cindy; van Zuiden, Mirjam; Koch, Saskia B J; Frijling, Jessie L; Veltman, Dick J; Olff, Miranda; Nawijn, Laura (Co-Action Publishing, 2023-11-23)
    Background: Alexithymia, an inability to recognise one’s emotions, has been associated with trauma-exposure and posttraumatic stress disorder (PTSD). Previous research suggests involvement of the oxytocin system, and ...