Abstract
1. 1. Sonication of bovine liver microsomes completely solubilized the membrane-bound lysophospholipase II (EC 3.1.1.5). Co-chromatography with purified 125I-labelled lysophospholipase indicated that the enzyme was solubilized from microsomes in a lipid-free state.
2. 2. In the presence of residual microsomal membranes, the solubilized lysophospholipase could only be partly degraded by trypsin
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