Clinical implications of frequency-force relation

Abstract

In order to assess the frequency-force relationship in man, the relation between RR intervals and timing of dosing and opening sounds of a prosthetic mitral valve was studied by means of cross-correlation techniques in eight patients with atrial fibrillation. The relation between RR intervals and aortic blood flow velocity was also studied with the same techniques in three patients with atrial fibrillation during thoracotomy. Frequency-force relation could be demonstrated in the cross-correlograms between RR interval and the interval between the occurrence of the R wave and the mitral valve dosing sound and also in the crosscorrelograms between RR interval and aortic blood flow parameters such as stroke volume.