Abstract
The adenovirus ElA gene products are nuclear
phosphoproteins that can transactivate the other
adenovirus early genes as well as several cellular genes,
and can transform primary rodent cells in culture.
Transformation and transactivation by ElA proteins
is most likely to be mediated through binding to several
cellular proteins, including the retinoblastoma gene
product pRb, the pRb-related p107
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