Abstract
To distinguish between antigenic stimulation and CD4+ T-cell homeostasis
as the cause of T-cell hyperactivation in HIV infection, we studied T-cell activation in
47 patients before and during highly active antiretroviral therapy (HAART). We show
that expression of human leukocyte antigen (HLA)-DR, CD38, and Ki67 on T cells
decreased during HAART but remained elevated
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