Abstract
We have isolated a cDNA encoding a transcription
factor that binds to the enhancer of major histocompatibility
complex (MHC) class I genes. MHC-binding protein 2
(MBP-2) is a 275-kDa protein, containing two sets of widely
separated zinc fingers and a stretch of highly acidic amino acids,
a putative transactivation domain. The two zinc ringer regions,
when
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