Abstract
Twenty-one cases of β⁰- and β⁺-thalassaemia have been
analysed by restriction endonuclease mapping. In most cases
no deletion in the regions surrounding the β- and δ-globin
genes could be detected. However, in a single Asian case of
β⁰-thalassaemia, homozygous clinically, one of the homologous
chromosomes contained a β-globin gene with a deletion of 600
base pairs
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