Abstract
Cytosolic phospholipase A2 (cPLA2) plays a critical
role in various neutrophil functions including the generation of
leukotrienes and platelet-activating factor release. Enzyme
activity is regulated both by translocation to the membrane in
a Ca^(2+) -dependent manner and serine phosphorylation by
members of the mitogen-activated protein kinase (MAPK)
family. In this report, we have investigated the role
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