Abstract
Abstract Interleukin-1ß (IL-1ß) is a potent inflammatory
cytokine involved in type 1 diabetes and acts through defined
IL-1ß signaling pathways. In the present work we describe
induction of DNA binding activity to signal transducer and
activator of transcription (STAT) in response to IL-1ß in clonal
insulin-secreting cells. Moreover, IL-1ß activates a short isoform
of STAT-3 that
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